Sulfur Extrusion with Tin Radical: Synthesis of 4′,5′ -Didehydro-5′-deoxy-5′-(tributylstannyl)adenosine, an Intermediate for Potential Inhibitors against S-Adenosyl Homocysteine Hydrolase

Journal of Organic Chemistry

Volumn 69, Issue 1, 2004, Pages 72-78

  Kumamoto, Hiroki ^a   Onuma, Sayoko ^a   Tanaka, Hiromichi ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CHEMICAL BONDS; ISOMERS; REACTION KINETICS; SUBSTRATES; SULFUR; SYNTHESIS (CHEMICAL);

FLUORINATION; IODINATION;

ORGANIC COMPOUNDS;

2,3 DIHYDRO 4 (TRIBUTYLSTANNYL)FURAN; 2,3 DIHYDRO 4 PHENYLTHIOFURAN; 4',5' DIDEHYDRO 5' DEOXY 5' (PHENYLTHIO)ADENOSINE; 4',5' DIDEHYDRO 5' DEOXY 5' (TRIBUTYLSTANNYL)ADENOSINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 (TRIBUTYLSTANNYL) 5 DEOXY BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 CHLORO 5 DEOXY BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 CYANO 5 DEOXY BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY 5 (PHENYLTHIO) BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY 5 (TRIFLUOROVINYL) BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY 5 (TRIMETHYLSILYLETHYNYL) BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY 5 FLUORO BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY 5 IODO BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY 5 PHENYL BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY 5 VINYL BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; 9 [5 BROMO 2,3 BIS O (TERT BUTYLDIMETHYLSILYL) 5 DEOXY BETA DEXTRO ERYTHRO PENT 4 ENOFURANOSYL]ADENINE; ADENINE DERIVATIVE; ADENOSINE DERIVATIVE; ADENOSYLHOMOCYSTEINASE; ADENOSYLHOMOCYSTEINASE INHIBITOR; FLUORIDE; IODINE DERIVATIVE; NITRILE; PHENYL GROUP; SULFUR; TIN; TRIBUTYL (2 ETHOXYVINYL)TIN; TRIBUTYLTIN; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

ARTICLE; BROMINATION; CHEMICAL BOND; CHEMICAL REACTION; CHLORINATION; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORINATION; IODINATION; ISOMER; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; TECHNIQUE;

ADENOSINE; ADENOSYLHOMOCYSTEINASE; ENZYME INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; SPECTROPHOTOMETRY, ULTRAVIOLET; SULFUR; TIN;

EID: 0346731108     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo030256y     Document Type: Article

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