New Tools Studying Vesicular-Mediated Protein Trafficking: Synthesis and Evaluation of Ilimaquinone Analogs in a Non-Radioisotope-Based Antisecretory Assay

Journal of Organic Chemistry

Volumn 62, Issue 9, 1997, Pages 2823-2831

  Radeke, Heike S ^a   Digits, Cheryl A ^a,b   Bruner, Steven D ^a   Snapper, Marc L ^a  

^a BOSTON COLLEGE   (United States)

^b Department of Education ^*

Author keywords

[No Author keywords available]

Indexed keywords

QUINONE DERIVATIVE; SESQUITERPENE DERIVATIVE; STOMACH SECRETION INHIBITOR;

ANIMAL CELL; ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; GOLGI COMPLEX; NONHUMAN;

EID: 0030984935     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo962292l     Document Type: Article

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41. The Jurkat cells were modified to constituitively express the T-antigen. This allows for replication of the plasmid through its SV40 promoter (Mr. Peter Belshaw, Harvard University).
42. Analog 22 has also been shown to vesiculate the Golgi apparatus in a manner similar to ilimaquinone (C. Jamora and V. Malhotra, UCSD).
43. Radeke, H. S.; Bruner, S. D.; Digits, C. A.; Snapper, M. L. Manuscript in preparation.
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