Absorption of bioactive compounds from steamed broccoli and their effect on plasma glutathione S-transferase activity

International Journal of Food Sciences and Nutrition

Volumn 60, Issue SUPPL. 1, 2009, Pages 56-71

  Riso, Patrizia ^a   Brusamolino, Antonella ^a   Moro, Massimo ^b   Porrini, Marisa ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Bioactive compounds; Biomarker; Humans; Nutritional intervention; Vegetables

Indexed keywords

ALPHA CAROTENE; ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; BETA CRYPTOXANTHIN; CAROTENOID; FOLIC ACID; GLUCOSINOLATE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; ISOTHIOCYANIC ACID; LYCOPENE; RETINOL; THIOGLUCOSIDASE; XANTHOPHYLL; ZEAXANTHIN;

ADULT; ARTICLE; BIOAVAILABILITY; BLOOD LEVEL; BROCCOLI; CHEMICAL REACTION; CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; CYCLOCONDENSATION REACTION; DNA POLYMORPHISM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; FOOD INTAKE; GENOTYPE; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; NUTRIENT CONTENT;

ADULT; ASCORBIC ACID; BRASSICA; CAROTENOIDS; CROSS-OVER STUDIES; FOLIC ACID; GENOTYPE; GLUCOSINOLATES; GLUTATHIONE TRANSFERASE; HUMANS; ISOTHIOCYANATES; MALE; POLYMORPHISM, GENETIC; YOUNG ADULT;

BRASSICA OLERACEA VAR. ITALICA;

EID: 68949191152     PISSN: 09637486     EISSN: 14653478     Source Type: Journal    
DOI: 10.1080/09637480802089751     Document Type: Article

References (29)

1. Ashfield-Watt PA, Whiting JM, Clark ZE, Moat SJ, Newcombe RG, Burr ML, McDowell IF. 2003. A comparison of the effect of advice to eat either '5-a-day' fruit and vegetables or folic acid-fortified foods on plasma folate and homocysteine. Eur J Clin Nutr 57(2):316-323.
2. Blakley RL, Cocco L. 1984. Dismutation of dihydrofolate by dihydrofolate reductase. Biochem 23:2377-2383.
3. Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. 1995. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 274(13):1049-1057.
4. Conaway CC, Getahun SM, Liebes LL, Pusateri DJ, Topham DKW, Botero-Omary M, Chung F-L. 2000. Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli. Nutr Cancer 38(2):168-178.
5. Fimognari C, Hrelia P. 2007. Sulforaphane as a promising molecule for fighting cancer. Mutat Res 635 (2-3):90-104.
6. Gasper AV, Al-Janobi A, Smith JA, Bacon JR, Fortun P, Atheron C, Taylor MA, Hawkey CJ, Barrett DA, Mithen RF. 2005. Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli. Am J Clin Nutr 82(6):1283-1291.
7. Giovannucci E, Rimm EB, Liu Y, Stampfer MJ, Willett WC. 2003. A prospective study of cruciferous vegetables and prostate cancer. Cancer Epidemiol Biomarkers Prev 12(12):1403-1409.
8. Granado F, Olmedilla B, Herrero C, Perez-Sacristan B, Blanco I, Blazquez S. 2006. Bioavailability of carotenoids and tocopherols from broccoli: In vivo and in vitro assessment. Exp Biol Med 231(811):1733-1738.
9. Kim YI. 1999. Folate and carcinogenesis: Evidence, mechanisms, and implications. J Nutr Biochem 10(2):66-88.
10. Lampe JW, Peterson S. 2002. Brassica biotransformation and cancer risk: Genetic polymorphisms alter the preventive effects of cruciferous vegetables. J Nutr 132(10):2991-2994.
11. Liebes L, Conaway CC, Hochster H, Mendoza S, Hecht SS, Crowell J, Chung F-L. 2001. High-performance liquid chromatography-based determination of total isothiocyanate levels in human plasma: Application to studies with 2-phenethyl isothiocyanate. Anal Biochem 291(2):279-289.
12. London SJ, Yuan JM, Chung F-L, Gao YT, Coetzee GA, Ross RK, Yu MC. 2000. Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: A prospective study of men in Shanghai, China. Lancet 356(9231):724-729.
13. Porrini M, Riso P, Testolin G. 1998. Absorption of lycopene from single or daily portions of raw and processed tomato. Br J Nutr 80(4):353-361.
14. Riso P, Visioli F, Erba D, Testolin G, Porrini M. 2004. Lycopene and vitamin C concentrations increase in plasma and lymphocytes after tomato intake. Effects on cellular antioxidant protection. Eur J Clin Nutr 58(10):1350-1358.
15. Seow A, Yuan JM, Sun CL, Van den Berg D, Lee HP, YuMC. 2002. Dietary isothiocyanates, glutathione Stransferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis 23(12):2055-2061.
16. Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P. 1998. Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. Cancer Epidemiol Biomarkers Prev 7(12):1091-1100.
17. Song L, Morrison JJ, Botting NP, Thornalley PJ. 2005. Analysis of glucosinolates, isothiocyanates, and amine degradation products in vegetable extracts and blood plasma by LC-MS/MS. Anal Biochem 347(2):234-243.
18. Song L, Thornalley PJ. 2006. Effect of storage, processing and cooking on glucosinolate content of Brassica vegetables. Food Chem Toxicol 45(2):216-224.
19. Spitz MR, Duphorne CM, Detry MA, Pillow PC, Amos CI, Lei L, de Andrade M, Gu X, Hong WK,Wu X. 2000. Dietary intake of isothiocyanates: Evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk. Cancer Epidemiol. Biomarkers Prev 9(10):1017-1020.
20. Steck SE, Gammon MD, Hebert JR, Wall DE, Zeisel SH. 2007. GSTM1, GSTT1, GSTP1, and GSTA1 polymorphisms and urinary isothiocyanate metabolites following broccoli consumption in humans. J Nutr 137(4):904-909.
21. Thornalley PJ. 2002. Isothiocyanates: Mechanism of cancer chemopreventive action. Anti-Cancer Drugs 13(4):331-338.
22. van het Hof KH, Tijburg LB, Pietrzik K, Weststrate JA. 1999. Influence of feeding different vegetables on plasma levels of carotenoids, folate and vitamin C. Effect of disruption of the vegetable matrix. Br J Nutr 82(3):203-212.
23. van Poppel G, Verhoeven DT, Verhagen H, Goldbohm RA. 1999. Brassica vegetables and cancer prevention. Epidemiology and mechanisms. Adv Exp Med Biol 472:159-168.
24. Verhoeven DT, Goldbohm RA, van Poppel G, Verhagen H, van den Brandt PA. 1996. Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiol Biomark Prev 5(9):733-748.
25. Wang LI, Giovannucci EL, Hunter D, Neuberg GD, Su L, Christiani DC. 2004. Dietary intake of Cruciferous vegetables, glutathione S-transferase (GST) polymorphisms and lung cancer risk in a Caucasian population. Cancer Causes Control 15(10):977-985.
26. Ye L, Dinkova-Kostova AT,Wade KL, Zhang Y, Shapiro TA, Talalay P. 2002. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: Pharmacokinetics of broccoli sprout isothiocyanates in humans. Clin Chim Acta 316(1-2):43-53.
27. Zhang Y. 2001. Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates. Carcinogenesis 22(3):425-431.
28. Zhang Y, Wade KL, Prestera T, Talalay P. 1996. Quantitative determination of isothiocyanates, dithiocarbamates, carbon disulfide, and related thiocarbonyl compounds by cyclocondensation with 1,2-benzenedithiole. Anal Biochem 239(2):160-167.
29. Zhao B, Seow A, Lee EJ, Poh WT, Teh M, Eng P, Wang YT, Tan WC, Yu MC, Lee HP. 2001. Dietary isothiocyanates, glutathione S-transferase-M1, -T1 polymorphisms and lung cancer risk among Chinese women in Singapore. Cancer Epidemiol Biomarkers Prev 10(10):1063-1067.