Brevetoxin B is a clastogen in rats, but lacks mutagenic potential in the SP-98/100 Ames test

Toxicon

Volumn 54, Issue 6, 2009, Pages 851-856

  Leighfield, Tod A ^a   Muha, Noah ^a   Ramsdell, John S ^a  

^a CENTER FOR COASTAL ENVIRONMENTAL HEALTH AND BIOMOLECULAR RESEARCH   (United States)

Author keywords

Brevetoxin; DNA adducts; Epoxidation; Harmful algal bloom; Karenia brevis; Metabolism

Indexed keywords

BREVETOXIN B; CLASTOGEN; HISTIDINE; MARINE TOXIN; NEUROTOXIN; POLYETHER; UNCLASSIFIED DRUG;

AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ASSAY; CHROMOSOME ABERRATION; COMET ASSAY; DINOFLAGELLATE; DNA CONTENT; DNA FRAGMENTATION; DNA STRAND BREAKAGE; EPOXIDATION; FIBROBLAST CULTURE; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LUNG FIBROBLAST; LUNG PARENCHYMA; MALE; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERTANT;

ANIMALS; COMET ASSAY; DNA FRAGMENTATION; LIVER; MALE; MARINE TOXINS; MUTAGENICITY TESTS; MUTAGENS; OXOCINS; RATS; RATS, INBRED F344;

ALGAE; DINOPHYCEAE; KARENIA BREVIS; RATTUS; TRICHECHIDAE;

EID: 68949161817     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.06.018     Document Type: Article

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