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Volumn 53, Issue 1, 2009, Pages 135-145

Cellular metabolism of brevetoxin (PbTx-2) by a monocyte cell line (U-937)

Author keywords

Brevetoxin; Conjugates; Immunotoxicity; Karenia brevis; Metabolites; PbTx 2; Red tide; U 937

Indexed keywords

BREVETOXIN; GLUTATHIONE;

EID: 57749103766     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.10.024     Document Type: Article
Times cited : (15)

References (73)
  • 1
    • 0032794659 scopus 로고    scopus 로고
    • Uptake and tissue distribution and excretion of brevetoxin 3 administered to rats by intratracheal instillation
    • Benson J.M., Tischler D.L., and Baden D.G. Uptake and tissue distribution and excretion of brevetoxin 3 administered to rats by intratracheal instillation. J. Toxicol. Environ. Health A 56 (1999) 345-355
    • (1999) J. Toxicol. Environ. Health A , vol.56 , pp. 345-355
    • Benson, J.M.1    Tischler, D.L.2    Baden, D.G.3
  • 4
    • 0031957397 scopus 로고    scopus 로고
    • Brevetoxicosis in manatees (Trichechus manatus latirostris) from the 1996 epizootic: gross, histopathologic, and immunocytochemical features
    • Bossart G.D., Baden D.G., Ewing R., Roberts B., and Wright S. Brevetoxicosis in manatees (Trichechus manatus latirostris) from the 1996 epizootic: gross, histopathologic, and immunocytochemical features. Toxicol. Pathol. 26 2 (1998) 276-282
    • (1998) Toxicol. Pathol. , vol.26 , Issue.2 , pp. 276-282
    • Bossart, G.D.1    Baden, D.G.2    Ewing, R.3    Roberts, B.4    Wright, S.5
  • 5
    • 0038358133 scopus 로고    scopus 로고
    • Type B brevetoxins show tissue selectively for voltage-gated sodium channels: comparison of brain, skeletal muscle and cardiac sodium channels
    • Bottein-Dechraoui M.Y., and Ramsdell J.S. Type B brevetoxins show tissue selectively for voltage-gated sodium channels: comparison of brain, skeletal muscle and cardiac sodium channels. Toxicon 41 7 (2003) 919-927
    • (2003) Toxicon , vol.41 , Issue.7 , pp. 919-927
    • Bottein-Dechraoui, M.Y.1    Ramsdell, J.S.2
  • 6
    • 9444236827 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B cells
    • Boverhof D.R., Tam E., Harney A.S., Crawford R.B., Kaminski N.E., and Zacharewski T.R. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B cells. Mol. Pharmacol. 66 6 (2004) 1662-1670
    • (2004) Mol. Pharmacol. , vol.66 , Issue.6 , pp. 1662-1670
    • Boverhof, D.R.1    Tam, E.2    Harney, A.S.3    Crawford, R.B.4    Kaminski, N.E.5    Zacharewski, T.R.6
  • 9
    • 0035876315 scopus 로고    scopus 로고
    • Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes. Evidence for catalytic activity and mRNA expression
    • Dey A., Parmar D., Dayal M., Dhawan A., and Seth P.K. Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes. Evidence for catalytic activity and mRNA expression. Life Sci. 69 (2001) 383-393
    • (2001) Life Sci. , vol.69 , pp. 383-393
    • Dey, A.1    Parmar, D.2    Dayal, M.3    Dhawan, A.4    Seth, P.K.5
  • 10
    • 0037063719 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes
    • Dey A., Parmar D., Dhawan A., Dash D., and Seth P.K. Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes. Life Sci. 71 21 (2002) 2509-2519
    • (2002) Life Sci. , vol.71 , Issue.21 , pp. 2509-2519
    • Dey, A.1    Parmar, D.2    Dhawan, A.3    Dash, D.4    Seth, P.K.5
  • 11
    • 20644468612 scopus 로고    scopus 로고
    • Evidence for cytochrome P450 2E1 catalytic activity and expression in rat blood lymphocytes
    • Dey A., Dhawan A., Kishore Seth P., and Parmar D. Evidence for cytochrome P450 2E1 catalytic activity and expression in rat blood lymphocytes. Life Sci. 77 10 (2005) 1082-1093
    • (2005) Life Sci. , vol.77 , Issue.10 , pp. 1082-1093
    • Dey, A.1    Dhawan, A.2    Kishore Seth, P.3    Parmar, D.4
  • 12
    • 33748681783 scopus 로고    scopus 로고
    • Evidence for cytochrome P450 3A expression and catalytic activity in rat blood lymphocytes
    • Dey A., Yadav S., Dhawan A., Seth P.K., and Parmar D. Evidence for cytochrome P450 3A expression and catalytic activity in rat blood lymphocytes. Life Sci. 79 18 (2006) 1729-1735
    • (2006) Life Sci. , vol.79 , Issue.18 , pp. 1729-1735
    • Dey, A.1    Yadav, S.2    Dhawan, A.3    Seth, P.K.4    Parmar, D.5
  • 13
    • 0038890841 scopus 로고    scopus 로고
    • Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction
    • Dröge W., and Holm E. Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction. FASEB J 11 (1997) 1077-1089
    • (1997) FASEB J , vol.11 , pp. 1077-1089
    • Dröge, W.1    Holm, E.2
  • 14
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Dröge W. Free radicals in the physiological control of cell function. Physiol. Rev. 82 (2002) 47-95
    • (2002) Physiol. Rev. , vol.82 , pp. 47-95
    • Dröge, W.1
  • 15
    • 0033038758 scopus 로고    scopus 로고
    • Concise review of the glutathione S-transferases and their significance to toxicology
    • Eaton D.L., and Bammler T.K. Concise review of the glutathione S-transferases and their significance to toxicology. Toxicol. Sci. 49 2 (1999) 156-164
    • (1999) Toxicol. Sci. , vol.49 , Issue.2 , pp. 156-164
    • Eaton, D.L.1    Bammler, T.K.2
  • 17
    • 84870227385 scopus 로고
    • Reaction of glutathione with conjugated carbonyls
    • Esterbauer H., Zollner H., and Scholz N. Reaction of glutathione with conjugated carbonyls. Z. Naturforsch. [C] 30 4 (1975) 466-473
    • (1975) Z. Naturforsch. [C] , vol.30 , Issue.4 , pp. 466-473
    • Esterbauer, H.1    Zollner, H.2    Scholz, N.3
  • 18
    • 1842822873 scopus 로고    scopus 로고
    • 12-O-Tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promoncytic cells
    • Fernández C., Ramos A.M., Sancho P., Amrán D., de Blas E., and Aller P. 12-O-Tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promoncytic cells. J. Biol. Chem. 270 5 (2004) 3877-3884
    • (2004) J. Biol. Chem. , vol.270 , Issue.5 , pp. 3877-3884
    • Fernández, C.1    Ramos, A.M.2    Sancho, P.3    Amrán, D.4    de Blas, E.5    Aller, P.6
  • 19
    • 0023267140 scopus 로고
    • Glutathione and lymphocyte activation: a function of ageing and auto-immune disease
    • Fidelus R.K., and Tsan M.F. Glutathione and lymphocyte activation: a function of ageing and auto-immune disease. Immunology 61 4 (1987) 503-508
    • (1987) Immunology , vol.61 , Issue.4 , pp. 503-508
    • Fidelus, R.K.1    Tsan, M.F.2
  • 25
    • 26944437097 scopus 로고    scopus 로고
    • Cytochrome P450 1B1 is required for 7,12-dimethylbenz(a)-anthracence (DMBA) induced spleen cell immunotoxicity
    • Gao J., Lauer F.T., Dunaway S., and Burchiel S.W. Cytochrome P450 1B1 is required for 7,12-dimethylbenz(a)-anthracence (DMBA) induced spleen cell immunotoxicity. Toxicol. Sci. 86 1 (2005) 68-74
    • (2005) Toxicol. Sci. , vol.86 , Issue.1 , pp. 68-74
    • Gao, J.1    Lauer, F.T.2    Dunaway, S.3    Burchiel, S.W.4
  • 26
    • 0033231162 scopus 로고    scopus 로고
    • Biologic and pharmacologic regulation of mammalian glutathione synthesis
    • Griffith O.W. Biologic and pharmacologic regulation of mammalian glutathione synthesis. Free Radic. Biol. Med. 27 (1999) 922-935
    • (1999) Free Radic. Biol. Med. , vol.27 , pp. 922-935
    • Griffith, O.W.1
  • 27
    • 0037504522 scopus 로고    scopus 로고
    • Effects of brevetoxins on murine myeloma SP2/O cells: aberrant cellular division
    • Han T.K., Derby M., Martin D.F., Wright S.D., and Dao M.L. Effects of brevetoxins on murine myeloma SP2/O cells: aberrant cellular division. Int. J. Toxicol. 22 (2003) 73-80
    • (2003) Int. J. Toxicol. , vol.22 , pp. 73-80
    • Han, T.K.1    Derby, M.2    Martin, D.F.3    Wright, S.D.4    Dao, M.L.5
  • 28
    • 41749098287 scopus 로고    scopus 로고
    • Lymphocyte cytochrome P450 expression: inducibility studies in male Wistar rats
    • Hannon-Fletcher M.P., and Barnett Y.A. Lymphocyte cytochrome P450 expression: inducibility studies in male Wistar rats. Br. J. Biomed. Sci. 65 1 (2008) 1-6
    • (2008) Br. J. Biomed. Sci. , vol.65 , Issue.1 , pp. 1-6
    • Hannon-Fletcher, M.P.1    Barnett, Y.A.2
  • 30
    • 0025611278 scopus 로고
    • The enzymes of detoxication
    • Jakoby W.B., and Ziegler D.M. The enzymes of detoxication. J. Biol. Chem. 265 34 (1990) 20715-20718
    • (1990) J. Biol. Chem. , vol.265 , Issue.34 , pp. 20715-20718
    • Jakoby, W.B.1    Ziegler, D.M.2
  • 31
    • 0037810382 scopus 로고    scopus 로고
    • Insights into the roles of cathepsins in antigen processing and presentation revealed by specific inhibitors
    • Katunuma N., Matsunaga Y., Himeno K., and Hayashi Y. Insights into the roles of cathepsins in antigen processing and presentation revealed by specific inhibitors. Biol. Chem. 384 (2003) 883-890
    • (2003) Biol. Chem. , vol.384 , pp. 883-890
    • Katunuma, N.1    Matsunaga, Y.2    Himeno, K.3    Hayashi, Y.4
  • 32
    • 34247535550 scopus 로고    scopus 로고
    • Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitity: implications for systemic disease and immunosenescence
    • Kim H.J., Baraja B., Chan R.C., and Nel A.E. Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitity: implications for systemic disease and immunosenescence. J. Allergy Clin. Immunol. 119 5 (2007) 1225-1233
    • (2007) J. Allergy Clin. Immunol. , vol.119 , Issue.5 , pp. 1225-1233
    • Kim, H.J.1    Baraja, B.2    Chan, R.C.3    Nel, A.E.4
  • 34
    • 0034671702 scopus 로고    scopus 로고
    • Specific DNA adducts induced by some mono-substituted epoxides in vitro and in vivo
    • Koskinen M., and Plna K. Specific DNA adducts induced by some mono-substituted epoxides in vitro and in vivo. Chem. Biol. Interact. 129 3 (2000) 209-229
    • (2000) Chem. Biol. Interact. , vol.129 , Issue.3 , pp. 209-229
    • Koskinen, M.1    Plna, K.2
  • 35
    • 0036490504 scopus 로고    scopus 로고
    • Clinicopathologic features of suspected brevetoxicosis in double-crested cormorants (Phalacrocorax auritus) along the Florida Gulf coast
    • Kreuder C., Mazet J.A.K., Bossart G.D., Carpenter T.E., Holyoak M., Elie M.S., and Wright S.D. Clinicopathologic features of suspected brevetoxicosis in double-crested cormorants (Phalacrocorax auritus) along the Florida Gulf coast. J. Zoo. Wildl. Med. 33 (2002) 8-15
    • (2002) J. Zoo. Wildl. Med. , vol.33 , pp. 8-15
    • Kreuder, C.1    Mazet, J.A.K.2    Bossart, G.D.3    Carpenter, T.E.4    Holyoak, M.5    Elie, M.S.6    Wright, S.D.7
  • 36
    • 37149046226 scopus 로고    scopus 로고
    • Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by benzo(alpha)pyrene and 2-aminofluorene metabolites
    • Lee M.E., and Urso P. Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by benzo(alpha)pyrene and 2-aminofluorene metabolites. Immunopharmacol. Immunotoxicol. 29 3-4 (2007) 425-438
    • (2007) Immunopharmacol. Immunotoxicol. , vol.29 , Issue.3-4 , pp. 425-438
    • Lee, M.E.1    Urso, P.2
  • 38
    • 24944579458 scopus 로고    scopus 로고
    • 1 toxicity by using buffalo granulocytes and agranulocytes in vitro
    • 1 toxicity by using buffalo granulocytes and agranulocytes in vitro. Altern. Lab. Anim. 33 4 (2005) 387-390
    • (2005) Altern. Lab. Anim. , vol.33 , Issue.4 , pp. 387-390
    • More, T.1    Ramalinga Reddy, G.2    Kumar, S.3
  • 39
    • 0037214849 scopus 로고    scopus 로고
    • Brevetoxin concentrations in marine aerosol: Human exposure levels during a Karenia brevis harmful algal bloom
    • Pierce R.H., Henry M.S., Blum P.C., Lyons J., Cheng Y.S., Yazzie D., and Zhou Y. Brevetoxin concentrations in marine aerosol: Human exposure levels during a Karenia brevis harmful algal bloom. Bull. Environ. Contam. Toxicol. 70 1 (2003) 161-165
    • (2003) Bull. Environ. Contam. Toxicol. , vol.70 , Issue.1 , pp. 161-165
    • Pierce, R.H.1    Henry, M.S.2    Blum, P.C.3    Lyons, J.4    Cheng, Y.S.5    Yazzie, D.6    Zhou, Y.7
  • 41
    • 37349061117 scopus 로고    scopus 로고
    • Brevetoxin abundance and composition during ECOHAB-Florida field monitoring cruises in the Gulf of Mexico
    • Pierce R., Henry M., and Blum P. Brevetoxin abundance and composition during ECOHAB-Florida field monitoring cruises in the Gulf of Mexico. Continental Shelf Res. 28 (2008) 45-58
    • (2008) Continental Shelf Res. , vol.28 , pp. 45-58
    • Pierce, R.1    Henry, M.2    Blum, P.3
  • 42
    • 14244267439 scopus 로고    scopus 로고
    • Brevetoxin metabolism and elimination in the Easter oyster (Crassostrea virginica) after controlled exposures to Karenia brevis
    • Plakas S.M., Wang Z., El Said K.R., Jester E.L.E., Granade H.R., Flewelling L., Scott P., and DickeyDickey R.W. Brevetoxin metabolism and elimination in the Easter oyster (Crassostrea virginica) after controlled exposures to Karenia brevis. Toxicon 44 (2004) 677-685
    • (2004) Toxicon , vol.44 , pp. 677-685
    • Plakas, S.M.1    Wang, Z.2    El Said, K.R.3    Jester, E.L.E.4    Granade, H.R.5    Flewelling, L.6    Scott, P.7    DickeyDickey, R.W.8
  • 43
    • 20544466177 scopus 로고    scopus 로고
    • Rapid identification of a rapid detoxification mechanism for brevetoxin in rats
    • Radwan F.F.Y., Wang Z., and Ramsdell J.S. Rapid identification of a rapid detoxification mechanism for brevetoxin in rats. Toxicol. Sci. 85 (2005) 839-846
    • (2005) Toxicol. Sci. , vol.85 , pp. 839-846
    • Radwan, F.F.Y.1    Wang, Z.2    Ramsdell, J.S.3
  • 44
    • 29544444101 scopus 로고    scopus 로고
    • Characterization of in vitro oxidative and conjugative metabolic pathways for brevetoxin (PbTx-2)
    • Radwan F.F.Y., and Ramsdell J.S. Characterization of in vitro oxidative and conjugative metabolic pathways for brevetoxin (PbTx-2). Toxicol. Sci. 89 1 (2006) 57-65
    • (2006) Toxicol. Sci. , vol.89 , Issue.1 , pp. 57-65
    • Radwan, F.F.Y.1    Ramsdell, J.S.2
  • 45
    • 46749149727 scopus 로고    scopus 로고
    • Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure
    • Radwan F.F.Y., and Ramsdell J.S. Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure. Environ. Health Perspect. 116 7 (2008) 930-936
    • (2008) Environ. Health Perspect. , vol.116 , Issue.7 , pp. 930-936
    • Radwan, F.F.Y.1    Ramsdell, J.S.2
  • 46
    • 0029147217 scopus 로고
    • Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress
    • Rahman I., Li X.Y., Donaldson K., Harrison D.J., and MacNee W. Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress. Am. J. Physiol. 269 (1995) L285-L292
    • (1995) Am. J. Physiol. , vol.269
    • Rahman, I.1    Li, X.Y.2    Donaldson, K.3    Harrison, D.J.4    MacNee, W.5
  • 47
    • 18544374589 scopus 로고    scopus 로고
    • Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukmic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells
    • Ramos A.M., Fernández C., Amrán D., Sancho P., de Blas E., and Aller P. Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukmic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells. Blood 105 (2005) 4013-4020
    • (2005) Blood , vol.105 , pp. 4013-4020
    • Ramos, A.M.1    Fernández, C.2    Amrán, D.3    Sancho, P.4    de Blas, E.5    Aller, P.6
  • 48
    • 27744466223 scopus 로고    scopus 로고
    • The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes
    • Sayer A., Hu Q., Bourdelais A.J., Baden D.G., and Gibson J.E. The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes. Arch. Toxicol. 79 (2005) 683-688
    • (2005) Arch. Toxicol. , vol.79 , pp. 683-688
    • Sayer, A.1    Hu, Q.2    Bourdelais, A.J.3    Baden, D.G.4    Gibson, J.E.5
  • 49
    • 33744903108 scopus 로고    scopus 로고
    • The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro
    • Sayer A.N., Hu Q., Bourdelais A.J., Baden D.G., and Gibson J.E. The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro. Food Chem. Toxicol. 44 7 (2006) 1082-1091
    • (2006) Food Chem. Toxicol. , vol.44 , Issue.7 , pp. 1082-1091
    • Sayer, A.N.1    Hu, Q.2    Bourdelais, A.J.3    Baden, D.G.4    Gibson, J.E.5
  • 51
    • 0033650023 scopus 로고    scopus 로고
    • Cellular thiols and redox-regulated signal transduction
    • Sen C.K. Cellular thiols and redox-regulated signal transduction. Curr. Top. Cell. Regul. 36 (2000) 1-30
    • (2000) Curr. Top. Cell. Regul. , vol.36 , pp. 1-30
    • Sen, C.K.1
  • 52
    • 37549069338 scopus 로고    scopus 로고
    • Transcription factor and drug-metabolizing enzyme gene expression in lymphocytes from healthy human subjects
    • Siest G., Jeannesson E., Marteau J.B., Samara A., Marie B., Pfister M., and Visvikis-Siest S. Transcription factor and drug-metabolizing enzyme gene expression in lymphocytes from healthy human subjects. Drug Metab. Dispos. 36 1 (2008) 182-189
    • (2008) Drug Metab. Dispos. , vol.36 , Issue.1 , pp. 182-189
    • Siest, G.1    Jeannesson, E.2    Marteau, J.B.3    Samara, A.4    Marie, B.5    Pfister, M.6    Visvikis-Siest, S.7
  • 53
    • 0035098162 scopus 로고    scopus 로고
    • Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites
    • Srinivasan A., Lehmler H.J., Robertson L.W., and Ludewig G. Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites. Toxicol. Sci. 60 1 (2001) 92-102
    • (2001) Toxicol. Sci. , vol.60 , Issue.1 , pp. 92-102
    • Srinivasan, A.1    Lehmler, H.J.2    Robertson, L.W.3    Ludewig, G.4
  • 54
    • 0026875036 scopus 로고
    • An approach to computer-aided inhibitor design: application to cathepsin L
    • Sudarsanam S., Virca G.D., March C.J., and Srinivasan S. An approach to computer-aided inhibitor design: application to cathepsin L. J. Comput. Aided Mol. Des. 6 3 (1992) 223-233
    • (1992) J. Comput. Aided Mol. Des. , vol.6 , Issue.3 , pp. 223-233
    • Sudarsanam, S.1    Virca, G.D.2    March, C.J.3    Srinivasan, S.4
  • 55
    • 0017155490 scopus 로고
    • Establishment and characterization of a human lymphoma cell line (U-937)
    • Sundström C., and Nilsson K. Establishment and characterization of a human lymphoma cell line (U-937). Int. J. Cancer 17 5 (1976) 565-577
    • (1976) Int. J. Cancer , vol.17 , Issue.5 , pp. 565-577
    • Sundström, C.1    Nilsson, K.2
  • 56
    • 33746765670 scopus 로고    scopus 로고
    • Uptake, tissue distribution, and excretion of brevetoxin-3 administered to mice by intratracheal instillation
    • Tibbetts B.M., Baden D.G., and Benson J.M. Uptake, tissue distribution, and excretion of brevetoxin-3 administered to mice by intratracheal instillation. J. Toxicol. Environ. Health A 69 14 (2006) 1325-1335
    • (2006) J. Toxicol. Environ. Health A , vol.69 , Issue.14 , pp. 1325-1335
    • Tibbetts, B.M.1    Baden, D.G.2    Benson, J.M.3
  • 57
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Anal. Biochem. 27 (1969) 502-522
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 59
    • 0035861744 scopus 로고    scopus 로고
    • Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells
    • Troyano A., Fernández C., Sancho P., de Blas E., and Aller P. Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. J. Biol. Chem. 276 50 (2001) 47107-47115
    • (2001) J. Biol. Chem. , vol.276 , Issue.50 , pp. 47107-47115
    • Troyano, A.1    Fernández, C.2    Sancho, P.3    de Blas, E.4    Aller, P.5
  • 60
    • 18144430252 scopus 로고    scopus 로고
    • Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: polymorphisms and interindividual variation in expression and inducibility
    • Van Duursen M.B.M., Sanderson J.T., and van den Berg M. Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: polymorphisms and interindividual variation in expression and inducibility. Toxicol. Sci. 85 (2005) 703-712
    • (2005) Toxicol. Sci. , vol.85 , pp. 703-712
    • Van Duursen, M.B.M.1    Sanderson, J.T.2    van den Berg, M.3
  • 61
    • 11144287431 scopus 로고    scopus 로고
    • Effects of environmental stressors on lymphocyte proliferation in the Florida manatee, Trichechus manatus latirostris
    • Walsh C.J., Luer C.A., and Noyes D.R. Effects of environmental stressors on lymphocyte proliferation in the Florida manatee, Trichechus manatus latirostris. Vet. Immunol. Immunopathol. 103 3-4 (2005) 247-256
    • (2005) Vet. Immunol. Immunopathol. , vol.103 , Issue.3-4 , pp. 247-256
    • Walsh, C.J.1    Luer, C.A.2    Noyes, D.R.3
  • 63
    • 46349094954 scopus 로고    scopus 로고
    • Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat)
    • Walsh C.J., Leggett S.R., Strohbehn K., Pierce R.H., and Sleasman J.W. Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat). Mar. Drugs 6 (2008) 291-307
    • (2008) Mar. Drugs , vol.6 , pp. 291-307
    • Walsh, C.J.1    Leggett, S.R.2    Strohbehn, K.3    Pierce, R.H.4    Sleasman, J.W.5
  • 64
    • 1642462821 scopus 로고    scopus 로고
    • LC/MS analysis of brevetoxin metabolites in the Eastern oyster (Crassostrea virginica)
    • Wang Z., Plakas S.M., El Said K.R., Jester E.L.E., Granade H.R., and Dickey R.W. LC/MS analysis of brevetoxin metabolites in the Eastern oyster (Crassostrea virginica). Toxicon 43 (2004) 455-465
    • (2004) Toxicon , vol.43 , pp. 455-465
    • Wang, Z.1    Plakas, S.M.2    El Said, K.R.3    Jester, E.L.E.4    Granade, H.R.5    Dickey, R.W.6
  • 65
    • 0028337323 scopus 로고
    • Brevetoxin: tissue distribution and effect on cytochrome P450 enzymes in fish
    • Washburn B.S., Baden D.G., Gassman N.J., and Walsh P.J. Brevetoxin: tissue distribution and effect on cytochrome P450 enzymes in fish. Toxicon 32 (1994) 799-805
    • (1994) Toxicon , vol.32 , pp. 799-805
    • Washburn, B.S.1    Baden, D.G.2    Gassman, N.J.3    Walsh, P.J.4
  • 66
    • 0030152508 scopus 로고    scopus 로고
    • Differential effects of brevetoxin and beta napthoflavone on xenobiotic metabolizing enzymes in striped bass
    • Washburn B.S., Vines C.A., Baden D.G., Hinton D.E., and Walsh P. Differential effects of brevetoxin and beta napthoflavone on xenobiotic metabolizing enzymes in striped bass. Aquat. Toxins 35 (1996) 1-10
    • (1996) Aquat. Toxins , vol.35 , pp. 1-10
    • Washburn, B.S.1    Vines, C.A.2    Baden, D.G.3    Hinton, D.E.4    Walsh, P.5
  • 67
    • 0142124282 scopus 로고    scopus 로고
    • Measurement of brevetoxin levels by radioimmunoassay of blood collection cards after acute, long-term, and low-dose exposure in mice
    • Woofter R., Dechraoui M.Y., Garthwaite I., Towers N.R., Gordon C.J., Cordova J., and Ramsdell J.S. Measurement of brevetoxin levels by radioimmunoassay of blood collection cards after acute, long-term, and low-dose exposure in mice. Environ. Health Perspect. 111 13 (2003) 1595-1600
    • (2003) Environ. Health Perspect. , vol.111 , Issue.13 , pp. 1595-1600
    • Woofter, R.1    Dechraoui, M.Y.2    Garthwaite, I.3    Towers, N.R.4    Gordon, C.J.5    Cordova, J.6    Ramsdell, J.S.7
  • 68
    • 12744280779 scopus 로고    scopus 로고
    • Uptake and elimination of brevetoxin in blood of striped mullet (Mugil cephalus) after aqueous exposure to Karenia brevis
    • Woofter R., Brendtro K., and Ramsdell J.S. Uptake and elimination of brevetoxin in blood of striped mullet (Mugil cephalus) after aqueous exposure to Karenia brevis. Environ. Health Perspect. 113 1 (2005) 11-16
    • (2005) Environ. Health Perspect. , vol.113 , Issue.1 , pp. 11-16
    • Woofter, R.1    Brendtro, K.2    Ramsdell, J.S.3
  • 69
    • 27744474845 scopus 로고    scopus 로고
    • Distribution of brevetoxin (PbTx-3) in mouse plasma: association with high-density lipoproteins
    • Woofter R.T., Spiess P.C., and Ramsdell J.S. Distribution of brevetoxin (PbTx-3) in mouse plasma: association with high-density lipoproteins. Environ. Health Perspect. 113 11 (2005) 1491-1496
    • (2005) Environ. Health Perspect. , vol.113 , Issue.11 , pp. 1491-1496
    • Woofter, R.T.1    Spiess, P.C.2    Ramsdell, J.S.3
  • 70
    • 34247627860 scopus 로고    scopus 로고
    • Distribution of brevetoxin to lipoproteins in human plasma
    • Woofter R.T., and Ramsdell J.S. Distribution of brevetoxin to lipoproteins in human plasma. Toxicon 49 7 (2007) 1010-1018
    • (2007) Toxicon , vol.49 , Issue.7 , pp. 1010-1018
    • Woofter, R.T.1    Ramsdell, J.S.2
  • 71
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • Wu G., Fang Y., Yang S., Lupton J.R., and Turner N.D. Glutathione metabolism and its implications for health. J. Nutr. 134 (2004) 489-492
    • (2004) J. Nutr. , vol.134 , pp. 489-492
    • Wu, G.1    Fang, Y.2    Yang, S.3    Lupton, J.R.4    Turner, N.D.5
  • 72
    • 0347379850 scopus 로고    scopus 로고
    • Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line
    • Xiao G.G., Wang M., Li N., Loo J.A., and Nel A.E. Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line. J. Biol. Chem. 278 50 (2003) 50781-50790
    • (2003) J. Biol. Chem. , vol.278 , Issue.50 , pp. 50781-50790
    • Xiao, G.G.1    Wang, M.2    Li, N.3    Loo, J.A.4    Nel, A.E.5
  • 73
    • 0036860951 scopus 로고    scopus 로고
    • Dose effect of oxidative stress on signal transduction in aging
    • Yoon S.O., Yun C.H., and Chung A.S. Dose effect of oxidative stress on signal transduction in aging. Mech. Ageing Dev. 123 12 (2002) 1597-1604
    • (2002) Mech. Ageing Dev. , vol.123 , Issue.12 , pp. 1597-1604
    • Yoon, S.O.1    Yun, C.H.2    Chung, A.S.3


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