Characterization of in vitro oxidative and conjugative metabolic pathways for brevetoxin (PbTx-2)

Toxicological Sciences

Volumn 89, Issue 1, 2006, Pages 57-65

  Radwan, Faisal F Y ^a,b   Ramsdell, John S ^a  

^a CENTER FOR COASTAL ENVIRONMENTAL HEALTH AND BIOMOLECULAR RESEARCH   (United States)

^b SOUTH VALLEY UNIVERSITY   (Egypt)

Author keywords

Brevetoxin metabolism; Conjugation; CYP; Cytochrome P450; In vitro; Karenia brevis; Red tide bloom

Indexed keywords

BREVETOXIN; CYSTEINE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2D1; CYTOCHROME P450 2E1; CYTOCHROME P450 3A1; GLUTATHIONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IN VITRO STUDY; LIVER CELL; MASS SPECTROMETRY; METABOLISM; METABOLITE; NONHUMAN; RAT; TOXICITY TESTING;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINOFLAGELLIDA; HEPATOCYTES; MALE; MARINE TOXINS; METABOLIC DETOXICATION, PHASE II; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; DINOPHYCEAE; KARENIA BREVIS;

EID: 29544444101     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj013     Document Type: Article

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