Structural and functional analysis of Campylobacter jejuni PseG. A UDP-sugar hydrolase from the pseudaminic acid biosynthetic pathway

Journal of Biological Chemistry

Volumn 284, Issue 31, 2009, Pages 20989-21000

  Rangarajan, Erumbi S ^a   Proteau, Ariane ^b   Cui, Qizhi ^b   Logan, Susan M ^b   Potetinova, Zhanna ^b   Whitfield, Dennis ^b   Purisima, Enrico O ^b   Cygler, Miroslaw ^a,b   Matte, Allan ^b   Sulea, Traian ^b   Schoenhofen, Ian C ^b  

^a MCGILL UNIVERSITY   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; AMINO ACID SUBSTITUTION; ANOMERICS; BIOSYNTHETIC PATHWAY; CAMPYLOBACTER JEJUNI; CATALYTIC REACTIONS; COORDINATED WATER; GLYCOSYL TRANSFERASE; HELICOBACTER PYLORI; HYDROLASES; MOLECULAR BASIS; NUCLEOTIDE SUGAR; PSEUDAMINIC ACID; SIALIC ACIDS; STRUCTURAL COMPARISON; SUBSTRATE COMPLEXES; TWIST-BOAT CONFORMATIONS; WATER MOLECULE;

AMINES; AMINO ACIDS; CARBOXYLIC ACIDS; CATALYSIS; COORDINATION REACTIONS; ESCHERICHIA COLI; INTERNET PROTOCOLS; MOLECULES; ORGANIC ACIDS; SUGAR (SUCROSE);

SUGARS;

AMINO ACID DERIVATIVE; BACTERIAL ENZYME; GLYCOSYLTRANSFERASE; GLYCOSYLTRANSFERASE MURG; HISTIDINE; LEUCINE; NUCLEOPHILE; PSEUDAMINIC ACID G ENZYME; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; URIDINE DIPHOSPHATE SUGAR; URIDINE DIPHOSPHATE SUGAR HYDROLASE; WATER;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BIOSYNTHESIS; CAMPYLOBACTER JEJUNI; CATALYSIS; CHEMICAL BOND; CONFORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; STRUCTURE ANALYSIS;

BACTERIAL OUTER MEMBRANE PROTEINS; BINDING SITES; BIOCATALYSIS; BIOSYNTHETIC PATHWAYS; CAMPYLOBACTER JEJUNI; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HELICOBACTER PYLORI; KINETICS; MODELS, MOLECULAR; MUTANT PROTEINS; N-ACETYLGLUCOSAMINYLTRANSFERASES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; SUGAR ACIDS; URIDINE DIPHOSPHATE SUGARS;

CAMPYLOBACTER JEJUNI; ESCHERICHIA COLI; HELICOBACTER PYLORI;

EID: 68949117916     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.012351     Document Type: Article

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