Homology between O-linked GlcNAc transferases and proteins of the glycogen phosphorylase superfamily

Journal of Molecular Biology

Volumn 314, Issue 3, 2001, Pages 365-374

  Wrabl, James O ^a   Grishin, Nick V ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Fold prediction; Glycogen phosphorylase; Glycosyl transferase; Homology detection; O linked GlcNAc transferase

Indexed keywords

GLYCOGEN PHOSPHORYLASE; HYDROXYL GROUP; N ACETYLGALACTOSAMINE; N ACETYLGALACTOSAMINYLTRANSFERASE; PEPTIDE DERIVATIVE; URIDINE DIPHOSPHATE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CANCER; CARBOXY TERMINAL SEQUENCE; DIABETES MELLITUS; ENZYME STRUCTURE; ESCHERICHIA COLI; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ESCHERICHIA COLI; EUKARYOTA;

EID: 0035976715     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5151     Document Type: Article

References (44)

1. O-Glycosylation of nuclear and cytosolic proteins. Dynamic interplay between O-GlcNAc and O-phosphate
2. The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny
3. Glycosylation of nucleocytosplasmic proteins: Signal transduction and O-GlcNAc
4. Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins
5. O-glycosylation of nuclear and cytoplasmic proteins: Regulation analogous to phosphorylation?
6. Reciprocity between O-GlcNAc and O-phosphate on the carboxy terminal domain of RNA polymerase II
7. RNA polymerase II is a glycoprotein
8. Structure of O-linked GlcNAc transferase: Mediator of glycan-dependent signaling
9. Gleaning non-trivial structural, functional and evolutionary information about proteins by iterative database searches
10. Homology among (betaalpha)(8) barrels: Implications for the evolution of metabolic pathways
11. GGDEF domain is homologous to adenylyl cyclase
12. A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities
13. Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics
14. Glycosyltransferase structure and mechanism
15. The structures and related functions of phosphorylase a
16. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
17. O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats
18. T-Coffee: A novel method for fast and accurate multiple sequence alignment
19. JPred: A consensus secondary structure prediction server
20. A novel resistance mechanism against beta-lactams in Streptococcus pneumoniae involves CpoA, a putative glycosyltransferase
21. SEALS: A system for easy analysis of lots of sequences
22. Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: Answers to a long outstanding question
23. The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases
24. The 1.9 Å crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis
25. beta-Glucosyltransferase and phosphorylase reveal their common theme
26. Evolutionary link between glycogen phosphorylase and a DNA modifying enzyme
27. The C-terminal domain of HPII catalase is a member of the type I glutamine amidotransferase superfamily
28. Identification of essential amino acids in the bacterial alpha - Mannosyltransferase aceA
29. Conserved domains of glycosyltransferases
30. Hybrid fold recognition: Combining sequence derived properties with evolutionary information
31. Sweet secrets of synthesis
32. Multidomain architecture of beta-glycosyl transferases: Implications for mechanism of action
33. Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs
34. T4 phage beta-glucosyltransferase: Substrate binding and proposed catalytic mechanism
35. Glycoside hydrolases and glycosyltransferases. Families, modules, and implications for genomics
36. The refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex
37. The role of pyridoxal-5′-phosphate in glycogen phosphorylase catalysis
38. Identification of two essential glutamic acid residues in glycogen synthase
39. Structure of the 30S ribosomal subunit
40. High resolution crystal structures of T4 phage beta-glucosyltransferase: Induced fit and effect of substrate and metal binding
41. Ribosomal protein structures: Insights into the architecture, machinery and evolution of the ribosome
42. A protein phosphorylation switch at the conserved allosteric site in GP
43. MOLSCRIPT: A program to produce both detailed and schematic plots of protein stucture
44. An extensively modified version of MolScript that includes greatly enhanced coloring capabilities