IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease

Journal of Immunology

Volumn 183, Issue 1, 2009, Pages 568-577

  Staschke, Kirk A ^a   Dong, Sucai ^a   Saha, Joy ^a   Zhao, Jingyong ^a   Brooks, Nathan A ^a   Hepburn, Deena L ^a   Xia, Jinqi ^a   Gulen, Muhammet F ^b   Kang, Zizhen ^b   Altuntas, Cengiz Z ^b   Tuohy, Vincent K ^b   Gilmour, Raymond ^a   Li, Xiaoxia ^b   Na, Songqing ^a  

^a ELI LILLY AND COMPANY   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 17; INTERLEUKIN 23 RECEPTOR; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; STAT3 PROTEIN; GLYCOPROTEIN; IL17A PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK4 PROTEIN, MOUSE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35 55); MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT;

ADOPTIVE TRANSFER; ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TH17 CELL; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; DRUG ANTAGONISM; ENZYME ACTIVATION; ENZYMOLOGY; FEMALE; GENE TARGETING; GENETICS; HELPER CELL; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MIGRATION INHIBITION; MOLECULAR GENETICS; MONONUCLEAR CELL; PATHOLOGY; PHYSIOLOGY; SPINAL CORD;

AMINO ACID SEQUENCE; ANIMALS; CELL DIFFERENTIATION; CELL MIGRATION INHIBITION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME ACTIVATION; FEMALE; GENE KNOCK-IN TECHNIQUES; GLYCOPROTEINS; IMMUNITY, INNATE; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-17; LEUKOCYTES, MONONUCLEAR; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; SIGNAL TRANSDUCTION; SPINAL CORD; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 68949094003     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802361     Document Type: Article

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