Metabolism of carbosulfan. I. Species differences in the in vitro biotransformation by mammalian hepatic microsomes including human

Chemico-Biological Interactions

Volumn 181, Issue 2, 2009, Pages 210-219

  Abass, Khaled ^a   Reponen, Petri ^a   Mattila, Sampo ^a   Pelkonen, Olavi ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

In vitro; Metabolism; P450; Pesticides; Risk assessment; Toxicokinetics

Indexed keywords

2,3 DIHYDRO 2,2 DIMETHYL 3 OXOBENZOFURAN 7 OL; 2,3 DIHYDRO 2,2 DIMETHYLBENZOFURANY 7 YL METHYLCARBAMATE; 2,3 DIHYDRO 3 HYDROXY 2,2 DIMETHYLBENZOFURAN 7 YLMETHYLCARBAMATE; 2,3 DIHYDRO 3 OXY 2,2 DIMETHYLBENZOFURAN 7 YLMETHYLCARBAMATE; 2,3 DIHYDRO 3,7 DIHYDROXY 2,2 DIMETHYLBENZOFURAN; 2,3 DIHYDRO 7 HYDROXY 2,2 DIMETHYLBENZOFURAN; CARBARIL; CARBOFURAN; CARBOSULFAN; TOXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOTRANSFORMATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOG; HUMAN; HYDROXYLATION; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LIVER CLEARANCE; LIVER MICROSOME METABOLISM; MASS SPECTROMETRY; MINIPIG; MONKEY; MOUSE; NONHUMAN; OXIDATION; RABBIT; RAT; RISK ASSESSMENT; SPECIES DIFFERENCE; TOXICOKINETICS;

ADULT; ANIMALS; BIOTRANSFORMATION; CARBAMATES; CHROMATOGRAPHY, LIQUID; DOGS; FEMALE; HAPLORHINI; HUMANS; MALE; MICE; MICROSOMES, LIVER; MIDDLE AGED; RABBITS; RATS; SPECIES SPECIFICITY; SWINE; SWINE, MINIATURE; TANDEM MASS SPECTROMETRY;

ANIMALIA; CANIS FAMILIARIS; MAMMALIA; ORYCTOLAGUS CUNICULUS; RATTUS;

EID: 68849088479     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.06.001     Document Type: Article

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