Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human α-synuclein in transgenic mouse brain

Human Molecular Genetics

Volumn 18, Issue 17, 2009, Pages 3274-3285

  Cronin, Kenneth D ^a   Ge, Dongliang ^a   Manninger, Paul ^b   Linnertz, Colton ^a   Rossoshek, Anna ^c   Orrison, Bonnie M ^c   Bernard, David J ^c   El Agnaf, Omar M A ^d   Schlossmacher, Michael G ^b   Nussbaum, Robert L ^e   Chiba Falek, Ornit ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; GENE PRODUCT; MESSENGER RNA; PROTEIN REP1; UNCLASSIFIED DRUG;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE LOCUS; GENE SEQUENCE; GENE TARGETING; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PRIORITY JOURNAL; TRANSGENIC MOUSE; UPREGULATION;

ALLELES; ALPHA-SYNUCLEIN; ANIMALS; BRAIN; FEMALE; HUMANS; MALE; MICE; MICE, TRANSGENIC; MICROSATELLITE REPEATS; PARKINSON DISEASE; POLYMORPHISM, GENETIC; UP-REGULATION;

MURINAE; MUS; MUS MUSCULUS;

EID: 68749088554     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp265     Document Type: Article

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