Bioengineered silk protein-based gene delivery systems

Biomaterials

Volumn 30, Issue 29, 2009, Pages 5775-5784

  Numata, Keiji ^a   Subramanian, Balajikarthick ^a   Currie, Heather A ^a   Kaplan, David L ^a  

^a Tufts University   (United States)

Author keywords

Bioengineering; DNA; Gene therapy; Nanoparticle; Silk

Indexed keywords

AGAROSE GEL ELECTROPHORESIS; BIOENGINEERING; CELL TRANSFECTION; CYTOTOXIC; DESIGN FEATURES; GENE DELIVERY; GENE DELIVERY SYSTEMS; GENE THERAPY; HUMAN EMBRYONIC KIDNEYS; IONIC COMPLEX; IONIC INTERACTION; L-LYSINE; LYSINE RESIDUES; MATERIAL SYSTEMS; PLASMID DNA; PLASMID DNA (PDNA); POLYLYSINE; ROBUST MATERIALS; SELF-ASSEMBLE; SELF-ASSEMBLED; SILK FILM; SILK PROTEINS;

AMINO ACIDS; ATOMIC FORCE MICROSCOPY; BLOCK COPOLYMERS; CELL MEMBRANES; COPOLYMERIZATION; DNA; ELECTROPHORESIS; GELATION; GENE TRANSFER; GENES; NANOPARTICLES; NUCLEIC ACIDS; PROTEINS;

SILK;

COPOLYMER; PLASMID DNA; POLYLYSINE; SILK FIBROIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; GENETIC ENGINEERING; HUMAN; HUMAN CELL; KIDNEY CELL; MOLECULAR INTERACTION; NONVIRAL GENE DELIVERY SYSTEM; NUCLEIC ACID IMMOBILIZATION; NUCLEOTIDE SEQUENCE; PARTICLE SIZE; PRIORITY JOURNAL; SILK;

CELL LINE; DNA; DRUG CARRIERS; FIBROINS; HUMANS; KIDNEY; MATERIALS TESTING; TRANSFECTION;

EID: 68549132265     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.06.028     Document Type: Article

References (49)

1. In: Kaplan D.L., Adams W.W., Farmer B., and Viney C. (Eds). Silk polymers: materials science and biotechnology. ACS Symp Ser (1994) 544
2. Altman G.H., Diaz F., Jakuba C., Calabro T., Horan R., Chen J., et al. Silk-based biomaterials. Biomaterials 24 (2003) 401-416
3. Wang Y., Kim H.-J., Vunjak-Novakovic G., and Kaplan D.L. Stem cell-based tissue engineering with silk biomaterials. Biomaterials 27 (2006) 6064-6082
4. Huemmerich D., Helsen C.W., Quedzuweit S., Oschmann J., Rudolph R., and Scheibel T. Primary structure elements of spider dragline silks and their contribution to protein solubility. Biochemistry 43 (2004) 13604-13612
5. Li M., Ogiso M., and Minoura N. Enzymatic degradation behavior of porous silk fibroin sheets. Biomaterials 24 (2003) 357-365
6. Wong C., Foo P., and Kaplan D.L. Genetic engineering of fibrous proteins: spider dragline silk and collagen. Adv Drug Deliv Rev 54 (2002) 1131-1143
7. Cappello J., Crissman J., Dorman M., Mikolajczak M., Textor G., Marquet M., et al. Genetic engineering of structural protein polymers. Biotechnol Prog 6 (1990) 198-202
8. Megeed Z., Cappello J., and Ghandehari H. Genetically engineered silk-elastinlike protein polymers for controlled drug delivery. Adv Drug Deliv Rev 54 (2002) 1075-1091
9. Megeed Z., Haider M., Li D., O'Malley Jr. B.W., Cappello J., and Ghandehari H. In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy. J Control Release 94 (2004) 433-445
10. Bini E., Foo C.W.P., Huang J., Karageorgiou V., Kitchel B., and Kaplan D.L. RGD-functionalized bioengineered spider dragline silk biomaterial. Biomacromolecules 7 (2006) 3139-3145
11. Szela S., Avtges P., Valluzzi R., Winkler S., Wilson D., Kirschner D., et al. Reduction-oxidation control of beta-sheet assembly in genetically engineered silk. Biomacromolecules 1 (2000) 534-542
12. Winkler S., Wilson D., and Kaplan D.L. Controlling beta-sheet assembly in genetically engineered silk by enzymatic phosphorylation/dephosphorylation. Biochemistry 39 (2000) 12739-12746
13. Wong Po Foo C., Patwardhan S.V., Belton D.J., Kitchel B., Anastasiades D., Huang J., et al. Novel nanocomposites from spider silk-silica fusion (chimeric) proteins. Proc Natl Acad Sci U S A 103 (2006) 9428-9433
14. Huang J., Wong C., George A., and Kaplan D.L. The effect of genetically engineered spider silk-dentin matrix protein 1 chimeric protein on hydroxyapatite nucleation. Biomaterials 28 (2007) 2358-2367
15. Rabotyagova O.S., Cebe P., and Kaplan D.L. Self-assembly of genetically engineered spider silk block copolymers. Biomacromolecules 10 (2009) 229-236
16. Zauner W., Ogris M., and Wagner E. Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv Drug Deliv Rev 30 (1998) 97-113
17. Ogris M., Brunner S., Schuller S., Kircheis R., and Wagner E. PEGylated DNA/transferring-PEI components, extended circulation in blood and potential for systemic gene delivery. Gene Ther 6 (1999) 595-605
18. Oupicky D., Konak C., Dash P.R., Seymour L.W., and Ulbrick K. Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block. Bioconjug Chem 10 (1999) 764-772
19. Breitenkamp R.B., and Emrick T. Pentalysine-grafted ROMP polymers for DNA complexation and delivery. Biomacromolecules 9 (2008) 2495-2500
20. Fischer D., Bieber T., Li Y., Elsässer H.-P., and Kissel T. A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency. Pharm Res 16 (1999) 1273-1279
21. Ahn C.-H., Chae S.Y., Bae Y.H., and Kim S.W. Biodegradable poly(ethylenimine) for plasmid DNA delivery. J Control Release 80 (2002) 273-282
22. Lavertu M., Methot S., Tran-Khanh N., and Buschmann M.D. High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation. Biomaterials 27 (2006) 4815-4824
23. Prince J.T., McGrath K.P., DiGirolamo C.M., and Kaplan D.L. Construction, cloning, and expression of synthetic genes encoding spider dragline silk. Biochemistry 34 (1995) 10879-10885
24. Huang J., Valluzzi R., Bini E., Vernaglia B., and Kaplan D.L. Cloning, expression, and assembly of sericin-like protein. J Biol Chem 278 (2003) 46117-46123
25. Yan S.Z., Beeler J.A., Chen Y., Shelton R.K., and Tang W.J. The regulation of type 7 adenylyl cyclase by its C1b region and Escherichia coli peptidylprolyl isomerase, SlyD. J Biol Chem 276 (2001) 8500-8506
26. Numata K., Kikkawa Y., Tsuge T., Iwata T., Doi Y., and Abe H. Adsorption of biopolyester depolymerase on silicon wafer and poly[(R)-3-hydroxybutyric acid] single crystal revealed by real-time AFM. Macromol Biosci 6 (2006) 41-50
27. Jin H.-J., and Kaplan D.L. Mechanism of silk processing in insects and spiders. Nature 424 (2003) 1057-1061
28. Thomas P., and Smart T.G. HEK293 cell line: a vehicle for the expression of recombinant proteins. J Pharmacol Toxicol Methods 51 (2005) 187-200
29. Blessing T., Remy J.-S., and Behr J.-P. Monomolecular collapse of plasmid DNA into stable virus-like particles. Proc Natl Acad Sci U S A 95 (1998) 1427-1431
30. Masotti A., Bordi F., Ortaggi G., Marino F., and Palocci C. A novel method to obtain chitosan/DNA nanospheres and a study of their release properties. Nanotechnology 19 55302 (2008) 6
31. Rejman J., Oberle V., Zuhorn I.S., and Hoekstra D. Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis. Biochem J 377 (2004) 159-169
32. Ross P.C., and Hui S.W. Lipoplex size is a major determinant of in vitro lipofection efficiency. Gene Ther 6 (1999) 651-659
33. Almofti M.R., Harashima H., Shinohara Y., Almofti A., Li W., and Kiwada H. Lipoplex size determines lipofection efficiency with or without serum. Mol Membr Biol 20 (2003) 35-43
34. Sato T., Ishii T., and Okahata Y. In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. Biomaterials 22 (2001) 2075-2080
35. Thanou M., Florea B.I., Geldof M., Junginger H.E., and Borchard G. Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines. Biomaterials 23 (2002) 153-159
36. Kataoka K., Harada A., and Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv Drug Deliv Rev 47 (2001) 113-131
37. Schaffert D., and Wagner E. Gene therapy progress and prospects: synthetic polymer-based systems. Gene Ther 15 (2008) 1131-1138
38. Luten J., van Nostrum C.F., De Smedt S.C., and Hennink W.E. Biodegradable polymers as non-viral carriers for plasmid DNA delivery. J Control Release 126 (2008) 97-110
39. Feng L., Guo M., Zhang S., Chu J., Zhuang Y., and Zhang S. Improvement in the suspension-culture production of recombinant adeno-associated virus-LacZ in HEK-293 cells using polyethyleneimine-DNA complexes in combination with hypothermic treatment. Biotechnol Appl Biochem 50 (2008) 121-132
40. Järver P., Langel K., El-Andaloussi S., and Langel U. Applications of cell-penetrating peptides in regulation of gene expression. Biochem Soc Trans 35 (2007) 770-774
41. Rittner K., Benavente A., Bompard-Sorlet A., Heitz F., Divita G., Brasseur R., et al. New basic membrane-destabilizing peptides for plasmid-based gene delivery in vitro and in vivo. Mol Ther 5 (2002) 104-114
42. Laakkonen P., Akerman M.E., Biliran H., Yang M., Ferrer F., Karpanen T., et al. Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells. Proc Natl Acad Sci U S A 101 (2004) 9381-9386
43. Laakkonen P., Zhang L., and Ruoslahti E. Peptide targeting of tumor lymph vessels. Ann N Y Acad Sci 1131 (2008) 37-43
44. Choi J.S., Lee E.J., Choi Y.H., Jeong Y.J., and Park J.S. Poly(ethylene glycol)-block-poly(l-lysine) dendrimer: novel linear polymer/dendrimer block copolymer forming a spherical water-soluble polyionic complex with DNA. Bioconjug Chem 10 (1999) 62-65
45. Gottschalk S., Sparrow J.T., Hauer J., Mims M.P., Leland F.E., Woo S.L., et al. A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther 3 (1996) 448-457
46. Segura T., and Shea L.D. Surface-tethered DNA complexes for enhanced gene delivery. Bioconjug Chem 13 (2002) 621-629
47. Shen H., Tan J., and Saltzman W.M. Surface-mediated gene transfer from nanocomposites of controlled texture. Nat Mater 3 (2004) 569-574
48. Park I.K., von Recum H.A., Jiang S., and Pun S.H. Supramolecular assembly of cyclodextrin-based nanoparticles on solid surfaces for gene delivery. Langmuir 22 (2006) 8478-8484
49. Jewell C.M., and Lynn D.M. Multilayered polyelectrolyte assemblies as platforms for the delivery of DNA and other nucleic acid-based therapeutics. Adv Drug Deliv Rev 60 (2008) 979-999