P38 mitogen-activated protein kinase (mapk) is activated by noradrenaline and serves a cardioprotective role, whereas adrenaline induces p38 mapk dephosphorylation

Clinical and Experimental Pharmacology and Physiology

Volumn 36, Issue 8, 2009, Pages

  Tsang, Michael Y C ^a   Rabkin, Simon W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

adrenoceptor; adrenoceptor; Extracellular signal regulated kinase 1 2; Heart apoptosis; Noradrenaline; P38 mitogen activated protein kinase

Indexed keywords

ADRENALIN; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BROMINE DERIVATIVE; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NORADRENALIN; PHENYLEPHRINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ASSAY; CELL DEATH; CELL STRUCTURE; CELL VIABILITY; CHICK EMBRYO; CONTROLLED STUDY; DNA FRAGMENTATION; EMBRYO; HEART MUSCLE CELL; HEART PROTECTION; MICROSCOPY; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC BETA-AGONISTS; ANIMALS; APOPTOSIS; CARDIOTONIC AGENTS; CELL SURVIVAL; CHICK EMBRYO; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPINEPHRINE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; NOREPINEPHRINE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, ADRENERGIC, BETA;

EID: 68549111112     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2009.05193.x     Document Type: Article

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