Inhibition of the cardiac p38-MAPK pathway by SB203580 delays ischemic cell death

Journal of Cardiovascular Pharmacology

Volumn 35, Issue 3, 2000, Pages 474-483

  Barancik, Miroslav ^a,b   Htun, Patrik ^a   Strohm, Claudia ^a   Kilian, Sven ^a   Schaper, Wolfgang ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Ischemia reperfusion; p38 MAPK; Pig; Protein kinases; SB203580

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; DIMETHYL SULFOXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME INHIBITION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SWINE;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DEATH; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; HEMODYNAMIC PROCESSES; IMIDAZOLES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRIDINES; SWINE;

EID: 0033998888     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200003000-00019     Document Type: Article

References (4)

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4. Barancik M, Htun P, Maeno Y, Zimmermann R, Schaper W. Differential regulation of distinct protein kinase cascades by ischemia and ischemia/reperfusion in porcine myocardium [Abstract]. Circulation 1997;96(Suppl I):1397.