Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution

AIDS Research and Therapy

Volumn 6, Issue , 2009, Pages

  Andrake, Mark D ^a   Ramcharan, Joseph ^b   Merkel, George ^a   Zhao, Xue Zhi ^c   Burke Jr , Terrence R ^c   Skalka, Anna Marie ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b Locus Pharmaceuticals Inc   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; INTEGRASE; INTEGRASE INHIBITOR; MAGNESIUM ION; MANGANESE; RADIOACTIVE MATERIAL; VIRUS DNA; VIRUS ENZYME;

ACCURACY; ARTICLE; AVIAN SARCOMA VIRUS; BINDING SITE; CATALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; ENZYME KINETICS; FLUORESCENCE ANALYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; INTERMETHOD COMPARISON; NONHUMAN; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; SCALE UP; SENSITIVITY ANALYSIS; SIGNAL NOISE RATIO; SPECIES COMPARISON; VALIDATION PROCESS; WILD TYPE;

EID: 68449101074     PISSN: 17426405     EISSN: None     Source Type: Journal    
DOI: 10.1186/1742-6405-6-14     Document Type: Article

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