Development and application of a high-throughput screening assay for HIV-1 integrase enzyme activities

Journal of Biomolecular Screening

Volumn 10, Issue 6, 2005, Pages 606-614

  John, Sinu ^a   Fletcher III, Thomas M ^b   Jonsson, Colleen B ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Assay development; High throughput screening (HTS); HIV; Integrase (IN)

Indexed keywords

BIOTIN; DIGOXIGENIN; INTEGRASE; NUCLEOSIDE ANALOG; RNA DIRECTED DNA POLYMERASE; STREPTAVIDIN; VIRUS DNA;

ARTICLE; ENZYME ACTIVITY; HIGH THROUGHPUT SCREENING; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; LONG TERMINAL REPEAT; NONHUMAN; PERFORMANCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; STATISTICAL ANALYSIS; VIRUS DNA CELL DNA INTERACTION;

BIOTIN; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; EDETIC ACID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GENOME, VIRAL; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1 REVERSE TRANSCRIPTASE; OLIGONUCLEOTIDES; STREPTAVIDIN; TERMINAL REPEAT SEQUENCES; TRANSCRIPTION, GENETIC;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 24944583304     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057105276318     Document Type: Article

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