2,3-Dihydro-6,7-dihydroxy-1H-isoindol-1-one-based HIV-1 integrase inhibitors

Journal of Medicinal Chemistry

Volumn 51, Issue 2, 2008, Pages 251-259

  Xue, Zhi Zhao ^a   Semenova, Elena A ^b   Vu, B Christie ^a   Maddali, Kasthuraiah ^b   Marchand, Christophe ^b   Hughes, Stephen H ^a   Pommier, Yves ^b   Burke Jr , Terrence R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 6,7 DIHYDROXY 1H ISOINDOL 1 ONE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; HYDRAZIDE DERIVATIVE; INTEGRASE; INTEGRASE INHIBITOR; ISOINDOLE DERIVATIVE; MANGANESE; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG SYNTHESIS; ENZYME INHIBITOR INTERACTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; NONHUMAN; STRUCTURE ACTIVITY RELATION;

BENZAMIDES; CATALYSIS; CATIONS, DIVALENT; CELL LINE; CELL LINE, TUMOR; GENETIC VECTORS; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; HYDRAZINES; ISOINDOLES; MAGNESIUM; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38349107592     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm070715d     Document Type: Article

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