Structural analysis of the human cannabinoid receptor one carboxyl-terminus identifies two amphipathic helices

Biopolymers

Volumn 91, Issue 7, 2009, Pages 565-573

  Ahn, Kwang H ^a   Pellegrini, Maria ^b   Tsomaia, Natia ^b   Yatawara, Achani K ^b   Kendall, Debra A ^a   Mierke, Dale F ^b,c  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b Dartmouth College   (United States)

^c Biomeasure Inc   (United States)

Author keywords

Amphipathic helices; Cannabinoid receptor one; CB1 carboxyl terminus; GPCR

Indexed keywords

AMPHIPATHIC; AQUEOUS SOLUTIONS; C-TERMINUS; CANNABINOID RECEPTOR ONE; CB1 CARBOXYL-TERMINUS; CIRCULAR DICHROISM; DISTAL REGIONS; FIRST DOMAIN; G-PROTEIN COUPLED RECEPTORS; GPCR; HELICAL CONFORMATION; HELICAL DOMAINS; HELICITIES; HELIX FORMATION; HUMAN CANNABINOID RECEPTORS; HYDROPHOBIC AND HYDROPHILIC; LOW CONCENTRATIONS; NMR SPECTROSCOPY; RECEPTOR ACTIVATION; SELF-ASSOCIATIONS; STRUCTURAL INFORMATION; STRUCTURAL MOTIFS; UNORDERED STRUCTURE; ZWITTERIONIC DETERGENTS; CANNABINOID RECEPTORS;

AMINES; ASSOCIATION REACTIONS; CELL MEMBRANES; CIRCULAR DICHROISM SPECTROSCOPY; DICHROISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; SOAPS (DETERGENTS); STRUCTURAL ANALYSIS; BIOMIMETICS;

BIOMIMETICS; CIRCULAR DICHROISM SPECTROSCOPY;

CANNABINOID RECEPTOR; CARBON 13; DODECYLPHOSPHORYLCHOLINE; G PROTEIN COUPLED RECEPTOR; NITROGEN 15; AMPHOLYTE; CANNABINOID 1 RECEPTOR; PEPTIDE;

ALPHA HELIX; AQUEOUS SOLUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; ESCHERICHIA COLI; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR MODEL; NONHUMAN; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; MOLECULAR DYNAMICS; NITROGEN NUCLEAR MAGNETIC RESONANCE; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; CIRCULAR DICHROISM; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CANNABINOID;

EID: 68349132226     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.21179     Document Type: Article

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