메뉴 건너뛰기




Volumn 19, Issue 10, 1999, Pages 3773-3780

Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization

Author keywords

Cannabinoid; Desensitization; G protein coupled receptor; G protein coupled receptor kinase; Inwardly rectifying potassium channel; Phosphorylation; arrestin

Indexed keywords

CANNABINOID RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; POTASSIUM CHANNEL; RETINA S ANTIGEN;

EID: 0033562607     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-10-03773.1999     Document Type: Article
Times cited : (218)

References (33)
  • 2
    • 0030662153 scopus 로고    scopus 로고
    • Agonist-induced phosphorylation of the kappa-opioid receptor
    • Appleyard SM, Patterson TA, Jin WZ, Chavkin C (1997) Agonist-induced phosphorylation of the kappa-opioid receptor. J Neurochem 69:2405-2412.
    • (1997) J Neurochem , vol.69 , pp. 2405-2412
    • Appleyard, S.M.1    Patterson, T.A.2    Jin, W.Z.3    Chavkin, C.4
  • 3
    • 0023897940 scopus 로고
    • Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization
    • Bouvier M, Hausdorff WP. De BA, O'Dowd BF, Kobilka BK, Caron MG, Lefkowitz RJ (1988) Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature 333:370-373.
    • (1988) Nature , vol.333 , pp. 370-373
    • Bouvier, M.1    Hausdorff, W.P.2    De, B.A.3    O'Dowd, B.F.4    Kobilka, B.K.5    Caron, M.G.6    Lefkowitz, R.J.7
  • 4
    • 0027415931 scopus 로고
    • Beta-adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation
    • Chen CY, Dion SB, Kim CM, Benovic JL (1993) Beta-adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation. J Biol Chem 268:7825-7831.
    • (1993) J Biol Chem , vol.268 , pp. 7825-7831
    • Chen, C.Y.1    Dion, S.B.2    Kim, C.M.3    Benovic, J.L.4
  • 6
    • 0022509199 scopus 로고
    • Cannabinoid pharmacology
    • Dewey WL (1986) Cannabinoid pharmacology. Pharmacol Rev 38:151-178.
    • (1986) Pharmacol Rev , vol.38 , pp. 151-178
    • Dewey, W.L.1
  • 8
    • 0023656534 scopus 로고
    • The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis
    • Dohlman HG, Bouvier M, Benovic JL, Caron MG, Lefkowitz RJ (1987) The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis. J Biol Chem 262:14282-14288.
    • (1987) J Biol Chem , vol.262 , pp. 14282-14288
    • Dohlman, H.G.1    Bouvier, M.2    Benovic, J.L.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 9
    • 0029719789 scopus 로고    scopus 로고
    • Desensitization of G protein-coupled receptors
    • Freedman NJ, Lefkowitz RJ (1996) Desensitization of G protein-coupled receptors. Recent Prog Horm Res 51:319-351.
    • (1996) Recent Prog Horm Res , vol.51 , pp. 319-351
    • Freedman, N.J.1    Lefkowitz, R.J.2
  • 10
    • 0032523019 scopus 로고    scopus 로고
    • Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor
    • Garcia DE, Brown S, Hille B, Mackie K (1998) Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor. J Neurosci 18:2834-2841.
    • (1998) J Neurosci , vol.18 , pp. 2834-2841
    • Garcia, D.E.1    Brown, S.2    Hille, B.3    Mackie, K.4
  • 11
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches
    • Hamill OP, Marty A, Neher E, Sakmann B, Sigworth F (1981) Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85-100.
    • (1981) Pflugers Arch , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.5
  • 12
    • 0028928974 scopus 로고
    • Activation of inwardly rectifying potassium channels (GIRK1) by co-expressed rat brain cannabinoid receptors in Xenopus oocyles
    • Henry DJ, Chavkin C ( 1995) Activation of inwardly rectifying potassium channels (GIRK1) by co-expressed rat brain cannabinoid receptors in Xenopus oocyles. Neurosci Lett 186:91-94.
    • (1995) Neurosci Lett , vol.186 , pp. 91-94
    • Henry, D.J.1    Chavkin, C.2
  • 13
    • 0032771955 scopus 로고    scopus 로고
    • Internalization and recycling of the CB1 cannabinoid receptor
    • in press
    • Hsieh C, Brown S, Derleth C, Mackie K (1999) Internalization and recycling of the CB1 cannabinoid receptor. J Neurochem, in press.
    • (1999) J Neurochem
    • Hsieh, C.1    Brown, S.2    Derleth, C.3    Mackie, K.4
  • 14
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 15
    • 0027368165 scopus 로고
    • Structure and mechanism of the G protein-coupled receptor kinases
    • Inglese J, Freedman NJ, Koch WJ, Lefkowitz RJ (1993) Structure and mechanism of the G protein-coupled receptor kinases. J Biol Chem 268:23735-23738.
    • (1993) J Biol Chem , vol.268 , pp. 23735-23738
    • Inglese, J.1    Freedman, N.J.2    Koch, W.J.3    Lefkowitz, R.J.4
  • 16
    • 0028985595 scopus 로고
    • Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1)
    • Kovoor A, Henry DJ, Chavkin C (1995) Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1). J Biol Chem 270:589-595.
    • (1995) J Biol Chem , vol.270 , pp. 589-595
    • Kovoor, A.1    Henry, D.J.2    Chavkin, C.3
  • 17
    • 0030736086 scopus 로고    scopus 로고
    • Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in Xenopus oocytes
    • Kovoor A, Nappey V, Kieffer BL, Chavkin C (1997) Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in Xenopus oocytes. J Biol Chem 272:27605-27611.
    • (1997) J Biol Chem , vol.272 , pp. 27605-27611
    • Kovoor, A.1    Nappey, V.2    Kieffer, B.L.3    Chavkin, C.4
  • 18
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G protein-coupled receptor regulation
    • Krupnick JG, Benovic JL (1998) The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38:289-319.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 19
    • 0026756371 scopus 로고
    • Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism
    • Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ (1992) Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism. J Biol Chem 267:4740-4746.
    • (1992) J Biol Chem , vol.267 , pp. 4740-4746
    • Liggett, S.B.1    Ostrowski, J.2    Chesnut, L.C.3    Kurose, H.4    Raymond, J.R.5    Caron, M.G.6    Lefkowitz, R.J.7
  • 20
    • 0030680131 scopus 로고    scopus 로고
    • Clathrin-mediated endocylosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1
    • Lin FT, Krueger KM, Kendall HE, Daaka Y, Fredericks ZL, Pitcher JA, Lefkowitz RJ (1997) Clathrin-mediated endocylosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1. J Biol Chem 272:31051-31057.
    • (1997) J Biol Chem , vol.272 , pp. 31051-31057
    • Lin, F.T.1    Krueger, K.M.2    Kendall, H.E.3    Daaka, Y.4    Fredericks, Z.L.5    Pitcher, J.A.6    Lefkowitz, R.J.7
  • 21
    • 0028823316 scopus 로고
    • Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor
    • Mackie K, Lai Y, Westenbroek R, Mitchell R (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J Neurosci 15:6552-6561.
    • (1995) J Neurosci , vol.15 , pp. 6552-6561
    • Mackie, K.1    Lai, Y.2    Westenbroek, R.3    Mitchell, R.4
  • 22
    • 0028185941 scopus 로고
    • Progress toward understanding the cannabinoid receptor and its second messenger systems
    • Martin BR, Welch SP, Abood M (1994) Progress toward understanding the cannabinoid receptor and its second messenger systems. Adv Pharmacol 25:341-397.
    • (1994) Adv Pharmacol , vol.25 , pp. 341-397
    • Martin, B.R.1    Welch, S.P.2    Abood, M.3
  • 23
    • 0030690545 scopus 로고    scopus 로고
    • Molecular aspects of cannabinoid receptors
    • Matsuda LA (1997) Molecular aspects of cannabinoid receptors. Crit Rev Neurobiol 11:143-166.
    • (1997) Crit Rev Neurobiol , vol.11 , pp. 143-166
    • Matsuda, L.A.1
  • 24
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 25
    • 0029085874 scopus 로고
    • Agonist-dependent phosphorylation of the mouse delta-opioid receptor: Involvement of G protein-coupled receptor kinases but not protein kinase C
    • Pei G, Kieffer BL, Lefkowitz RJ, Freedman NJ (1995) Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C. Mol Pharmacol 48:173-177.
    • (1995) Mol Pharmacol , vol.48 , pp. 173-177
    • Pei, G.1    Kieffer, B.L.2    Lefkowitz, R.J.3    Freedman, N.J.4
  • 26
    • 0027249634 scopus 로고
    • The evidence for the existence of cannabinoid receptors
    • Pertwee R (1993) The evidence for the existence of cannabinoid receptors. Gen Pharmacol 24:811-824.
    • (1993) Gen Pharmacol , vol.24 , pp. 811-824
    • Pertwee, R.1
  • 27
    • 0030611978 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid CB1 and CB2 receptors
    • Pertwee RG (1997) Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol Ther 74:129-180.
    • (1997) Pharmacol Ther , vol.74 , pp. 129-180
    • Pertwee, R.G.1
  • 29
    • 0029829841 scopus 로고    scopus 로고
    • Effects of chronic treatment with Delta(9)-tetrahydrocannabinol on cannabinoid-stimulated [S-35]GTP gamma S autoradiography in rat brain
    • Sim LJ, Hampson RE, Deadwyler SA, Childers SR (1996) Effects of chronic treatment with Delta(9)-tetrahydrocannabinol on cannabinoid-stimulated [S-35]GTP gamma S autoradiography in rat brain. J Neurosci 16:8057-8066.
    • (1996) J Neurosci , vol.16 , pp. 8057-8066
    • Sim, L.J.1    Hampson, R.E.2    Deadwyler, S.A.3    Childers, S.R.4
  • 31
    • 0030870722 scopus 로고    scopus 로고
    • A second endogenous cannabinoid that modulates long-term potentiation
    • Stella N, Schweitzer P, Piomelli D (1997) A second endogenous cannabinoid that modulates long-term potentiation. Nature 388:773-778.
    • (1997) Nature , vol.388 , pp. 773-778
    • Stella, N.1    Schweitzer, P.2    Piomelli, D.3
  • 32
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu TK, Hung DT, Wheaton VI, Coughlin SR (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64:1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 33
    • 0031393975 scopus 로고    scopus 로고
    • Molecular mechanisms of G protein-coupled receptor signaling: Role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization
    • Zhang J, Ferguson SS, Barak LS, Aber MJ, Giros B, Lefkowitz RJ, Caron MG (1997) Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization. Receptors Channels 5:193-199.
    • (1997) Receptors Channels , vol.5 , pp. 193-199
    • Zhang, J.1    Ferguson, S.S.2    Barak, L.S.3    Aber, M.J.4    Giros, B.5    Lefkowitz, R.J.6    Caron, M.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.