Cannabinoid receptor-G protein interactions: Gαi1-bound structures of IC3 and a mutant with altered G protein specificity

Protein Science

Volumn 11, Issue 10, 2002, Pages 2526-2531

  Ulfers, Amy L ^a   McMurry, Jonathan L ^b   Miller, Alexander ^b   Wang, Ligong ^a   Kendall, Debra A ^a,b   Mierke, Dale F ^a,b  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Cannabinoid receptor (CB1); Constitutively active receptors; G protein association; G protein coupled receptors; Third cytoplasmic loop (IC3); Transferred NOEs

Indexed keywords

ALANINE; AMINO ACID; CANNABINOID RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPROTEIN; LEUCINE; PEPTIDE; RECEPTOR SUBTYPE;

AMINO ACID SEQUENCE; ARTICLE; ATTENUATION; CARBOXY TERMINAL SEQUENCE; CORRELATION ANALYSIS; ENZYME ACTIVITY; IN VITRO STUDY; MUTATION; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; WILD TYPE;

GTP-BINDING PROTEINS; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036784635     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0218402     Document Type: Article

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