Mapping of ligand binding sites of the cholecystokinin-B/gastrin receptor with lipo-gastrin peptides and molecular modeling

Biopolymers

Volumn 41, Issue 7, 1997, Pages 799-817

  Lutz, Jürgen ^a   Romano Götsch, Roberta ^a   Escrieut, Chantal ^b   Fourmy, Daniel ^b   Mathä, Barbara ^c   Müller, Gerhard ^d   Kassler, Horst ^c   Moroder, Luis ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b CHU RANGUEIL   (France)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d BAYER AG   (Germany)

Author keywords

Cholecystokinin B gastrin receptor; Gastrin; Ligand binding sites; Lipo gastrin derivatives; Molecular modeling

Indexed keywords

BINDING ENERGY; BIOLOGY; CHEMICAL BONDS; METABOLISM; MOLECULAR STRUCTURE;

GASTRIN; MOLECULAR MODELING; PEPTIDES;

BIOCHEMISTRY;

CHOLECYSTOKININ B RECEPTOR; FATTY ACID; GASTRIN RECEPTOR; LIPOPEPTIDE; PENTAPEPTIDE; TETRAGASTRIN;

ANIMAL CELL; ARTICLE; BILAYER MEMBRANE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRAIN COS1; CONTROLLED STUDY; DERIVATIZATION; HORMONE RECEPTOR INTERACTION; LIGAND BINDING; LIPID COMPOSITION; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PEPTIDE MAPPING;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COS CELLS; GASTRINS; LIGANDS; LIPOPROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ;

EID: 0031172055     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0282(199706)41:7<799::AID-BIP8>3.0.CO;2-K     Document Type: Article

References (84)

1. Jensen, R. T., Wank, S. A., Rowley, W. H., Sato, S. & Gardner, J. D. (1989) Trends Pharmacol. Sci. 10, 418-423.
2. Walsh, J. H. (1994) Physiology of the Gastrointestinal Hormones, Vols. 1 and 2, Raven Press, New York.
3. Schwyzer, R. (1991) Biopolymers 31, 785-792.
4. Schwyzer, R. (1995) Biopolymers (Peptide Sci.) 37, 5-16.
5. Romano, R., Musiol, H.-J., Weyher, E., Dufresne, M. & Moroder, L. (1992) Biopolymers 32, 1545-1558.
6. Romano, R., Bayerl, T. M. & Moroder, L. (1993) Biochim. Biophys. Acta 1151, 111-119.
7. Moroder, L., Romano, R., Guba, W., Mierke, D. F., Kessler, H., Delporte, C., Winand, J. & Christophe, J. (1993b) Biochemistry 32, 13551-13559.
8. Wank, S. A., Harkins, R., Jensen, R. T., Shapira, H., de Weerth, A. & Slattery, T. (1992) Proc. Natl. Acad. Sci. USA 89, 3125-3129.
9. Wank, S. A., Pisegna, J. R. & de Weerth, A. (1992) Proc. Natl. Acad. Sci. USA 89, 8691-8695.
10. Pisegna, J. R., de Weerth, A., Huppi, K. & Wank, S. A. (1992) Biochem. Biophys. Chem. Commun. 189, 296-303.
11. Pisegna, J. R., de Weerth, A., Huppi, K. & Wank, S. A. (1994) Ann. NY Acad. Sci. 713, 338-342.
12. Kopin, A. S., Lee, Y.-M., McBride, E. W., Miller, L. J., Lu, M., Lin, H. Y., Kolakowski, L. F. & Beinborn, M. (1992) Proc. Natl. Acad. Sci. USA 89, 3605-3609.
13. de Weerth, A., Pisegna, J. R., Huppi, K. & Wank, S. A. (1993) Biochem. Biophys. Res. Commun. 194, 811-818.
14. de Weerth, A., Pisegna, J. R. & Wank, S. A. (1993b) Am. J. Physiol. 265, 1116-G1121.
15. de Weerth, A., Pisegna, J. R. & Wank, S. A. (1993c) Gastroenterology 104, A497.
16. Ulrich, C. D., Ferber, L, Holicky, E., Hadac, E., Buell, G. & Miller, L. J. (1993) Biochem. Biophys. Res. Commun. 193, 204-211.
17. Lee, Y. M., Beinborn, M., McBride, E. W., Lu, M., Kolakowski, L. F. & Kopin, A. S. (1993) J. Biol. Chem. 268, 8164-8169.
18. Ito, M., Matsui, T., Taniguchi, T., Tsukamoto, T., Murayama, T., Arima, N., Nakata, H., Chiba, T. & Chihara, K. (1993) J. Biol. Chem. 268, 18300-18305.
19. Reuben, M., Rising, L., Prinz, C., Hersey, S. & Sachs, G. (1994) Biochim. Biophys. Acta 1219, 321-327.
20. Tracy, H. J. & Gregory, R. A. (1964) Nature 204, 935-938.
21. Kopin, A. S., McBride, E. W., Quinn, S. M., Kolakowski, L. F. & Beinborn, M. (1995) J. Biol. Chem. 270, 5019-5023.
22. Beinborn, M., Lee, Y.-M., McBride, E. W., Quinn, S. M. & Kopin, A. S. (1993) Nature 362, 348-350.
23. Mantamadiotis, T. & Baldwin, G. S. (1994) Biochem. Biophys. Res. Commun. 201, 1382-1389.
24. Kennedy, K., Escrieut, C., Dufresne, M., Clerc, P., Vaysse, N. & Fourmy, D. (1995) Biochem. Biophys. Res. Commun. 213, 845-852.
25. Schmitz, F., Wu, M.-J., Pratt, D. S., Beinborn, M. & Kopin, A. S. (1995) Gastroenterology 108, A1004.
26. Ren, J., Avedian, D., Walsh, J. H. & Wu, S. V. (1995) Gastroenterology 108, A1202.
27. Poirot, S. S. & Wank, S. A. (1995) Gastroenterology 108, A845.
28. Jagerschmidt, A., Guillaume, N., Goudreau, N., Maigret, B. & Roques, B.-P. (1995) Mol. Pharmacol. 48, 783-789.
29. Wünsch, E., Moroder, L., Gillessen, D., Soerensen, U. B. & Bali, J.-P. (1982) Hoppe-Seyler's Z. Physiol. Chem. 363, 665-669.
30. Moroder, L., Göhring, W., Nyfeler, R., Scharf, R., Thamm, P. & Wendlberger, G. (1983) Hoppe-Seyler's Z. Physiol. Chem. 364, 151-171.
31. Dufresne, M., Escrieut, C., Clerc, P., Le Huerou-Luron, I., Prats, H., Bertrand, V., Le Meuth, V., Guilloteau, P., Vaysse, N. & Fourmy, D. (1996) Eur. J. Pharmacol. 297, 165-179.
32. Göhring, W., Moroder, L., Borin, G., Lobbia, A., Bali, J.-P. & Wünsch, E. (1984) Hoppe-Seyler's Z. Physiol. Chem. 365, 83-94.
33. Peggion, E., Jaeger, E., Knof, S., Moroder, L. & Wünsch, E. (1981) Biopolymers 20, 633-652.
34. Moroder, L., Musiol, H.-J. & Siglmüller, G. (1990) Synthesis, 889-892.
35. Lutz, J., Weyher, E. & Moroder, L. (1995) J. Peptide Sci. 1, 360-370.
36. Reindl, H. M. & Bayerl, T. M. (1993) Biochim. Biophys. Acta 1151, 127-136.
37. Koppel, D.E. (1972) J. Chem. Phys. 57, 4814-4820.
38. Degiorgio, V., Corti, M. & Giglio, M. (1980) Light Scattering in Liquids and Macromolecular Solutions, Plenum Press, New York.
39. Plattner, H. & Zingsheim, H. P. (1987) Methoden in der Elektronen-mikroskopie, Springer Verlag, Stuttgart.
40. Patry, V., Arnaud, E., Amalric, F. & Prats, H. (1994) Growth Factors 11, 163-174.
41. Prats, H., Kaghad, M., Prats, A.C., Klaksbrun. M., Léilas, J. M., Liauzun, P., Chalon, P., Tauber, J. P., Amalric, F., Smith, J. A. & Caput, D. (1989) Proc. Natl. Acad. Sci. USA 86, 1836-1840.
42. Hagler, A. T., Lifson, S. & Dauber, P. (1979) J. Am. Chem. Soc. 101, 5122-5130.
43. Kyle, D. J., Chakravarty, S., Sinske, J. A. & Stormann, T. M. (1994) J. Med. Chem. 37, 1347-1354.
44. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703.
45. Schertler, G. F. X., Villa, C. & Henderson, R. (1993) Nature 362, 770-772.
46. Unger, V. M. & Schertler, G. F. X. (1995) J. Biophys. 68, 1776-1786.
47. Baldwin, J. M. (1994) Curr. Opin. Cell Biol 6, 180-190.
48. Wess, J. (1993) Trends Pharmacol Sci. 14, 308-313.
49. Romano, R., Dufresne, M., Prost, M.-C., Bali, J.-P., Bayerl, T. M. & Moroder, L. (1993) Biochim, Biophys. Acta 1145, 235-242.
50. Mannock, D. A., Lewis, R. N. A. H., Sen, A. & Mcelhaney, R. N. (1988) Biochemistry 27, 6852-6859.
51. Hinz, H. J., Kuttenreich, H., Meyer, R., Renner, M. & Fruend, R. (1991) Biochemistry 30, 5125-5138.
52. Silvius, J. R. & Zuckermann, M. J. (1993) Biochemistry 32, 3153-3161.
53. Yamada, K., Ihara, H., Ide, T., Fukumoto, T. & Hirayama, C. (1984) Chem. Lett. 1713-1716.
54. Ihara, H., Fukumoto, T., Hirayama, C. & Yamada, K. (1986) Polym. Comm. 27, 282-285.
55. Murakami, Y., Nakano, A. & Ikeda, H. (1982) J. Org. Chem. 47, 2137-2144.
56. Macquaire, F., Baleux, F., Giaccobi, E., Huynh-Dinh, T., Neuman, J.-M. & Sanson, A. (1992) Biochemistry 31, 2576-2582.
57. Shimizu, T. & Hato, M. (1993) Biochim. Biophys. Acta 1147, 50-58.
58. Tanford, C. (1980) The Hydrophobie Effect: Formation of Micelles and Biological Membranes, 2nd ed., Wiley-Interscience, New York.
59. Nichols, J. W. (1985) Biochemistry 24, 6390-6398.
60. de Haas, G. H., Bonsen, P. P. M., Pieterson, W. A, & van Deenen, L. L. M. (1971) Biochim. Biophys. Ada 239, 252-266.
61. Dufresne, M., Escrieut, C., Clerc, P., Saillan, C., Kennedy, K., Fanjul, M., Mengod, G., Real, F., Moroder, L., Vaysse, N. & Fourmy, D. (1995) Digestion 56, 280.
62. Takeuchi, K., Speir, G. R. & Johnson, L. R. (1980) Am. J. Physiol 239, G395-G399.
63. Magous, R. & Bali, J.-P. (1982) Eur. J. Pharmacol 82, 47-54.
64. L. Moroder & E. Wünsch (1987) in Gastrin and Cholecystokinin: Chemistry, Physiology and Pharmacology, Bali, J.-P. & Martinez, J., Eds., Elsevier, Amsterdam, pp. 21-32.
65. Huang, S.-C., Fortune, K. P., Wank, S. A., Kopin, A. S, & Gardner, J. D. (1994) J. Biol Chem. 269, 26121-26126.
66. Jagerschmidt, A., Guillaume-Rousselet, N., Vikland, M.-L., Goudreau, N., Maigret, B. & Roques, B.-P. (1996) Eur. J. Pharmacol. 296, 97-106.
67. Hibert, M. F., Trumpp-Kallmeyer, S., Hoflack, J. & Bruinvels, A. (1993) Trends Pharmacol. Sci. 14, 7-12.
68. Teeter, M. M., Froimowitz, M., Stec, B. & DuRand, C. J. (1994) J. Med. Chem. 37, 2874-2888.
69. Martinez, J. (1990) in Comprehensive Medicinal Chemistry, Vol. 3, Hansch, C., Sammer, P. G. & Taylor, J. B., Eds., Pergamon Press, New York, pp. 925-959.
70. Moroder, L. & Lutz, J. (1996) in Studies in Natural Products Chemistry, Vol. 18, Attaur-Rahman, Ed., Elsevier Science BV, Amsterdam, pp. 819-873.
71. Wünsch, E., Moroder, L., Göhring, W., Borin, G., Calderan, A. & Bali, J.-P. (1986) FEBS Lett. 206, 203-207.
72. Huang, S. C., Yu, D.-H., Wank, S. A., Mantley, S., Gardner, J. D. & Jensen, R. T. (1989) Peptides 10, 785-789.
73. Silvente-Poirot, S. & Wank, S.A. (1996) J. Biol. Chem. 271, 14698-14706.
74. Ferrell, J. E., Jr., Lee, K.-J. & Huestis, W. (1985) Biochemistry 24, 2857-2864.
75. Silvius, J. R. & Leventis, R. (1993) Biochemistry 32, 13318-13326.
76. Vaz, W. L. C., Goodsaid-Zalduondo, F. & Jacobson, K. (1984) FEBS Lett. 174, 199-207.
77. Balcom, B. J. & Petersen, N. O. (1993) Biophys. J. 65, 630-637.
78. Schram, V. & Thompson, T. E. (1995) Biophys. J. 69, 2517-2520.
79. Mammi, S., Mammi, N.J. & Peggion, E. (1988) Biochemistry 27, 1374-1379.
80. Mammi, S. & Peggion, E. (1990) Biochemistry 29, 5265-5269.
81. Jackson, M. & Mantsch, H. H. (1992) Biochim. Biophys. Acta 1118, 139-143.
82. Quarzago, D. & Moroder, L. (1994) UPS 1, 171-177.
83. Miyake, A. (1995) Biochem. Biophys. Res. Commun. 208, 230-237.
84. Guba, W. & Kessler, H. (1994) J. Phys. Chem. 98, 23-27.