Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment

Journal of Structural Biology

Volumn 159, Issue 3, 2007, Pages 359-368

  Grace, Christy R R ^a   Cowsik, Sudha M ^b   Shim, Joong Youn ^c   Welsh, William J ^d   Howlett, Allyn C ^c  

^a CHRIST DEEMED TO BE UNIVERSITY   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

^c NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

^d RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Cell surface 7 transmembrane receptors; G protein coupled receptors; Signal transduction mechanisms; Sodium dodecyl sulfate (SDS) micelles; Two dimensional proton nuclear magnetic resonance (2D 1H NMR) spectroscopy

Indexed keywords

ARGINYLSERYLLYSYLASPARTYLLEUCYLARGINYLHISTIDYLALANYLPHENYLALANYLARGINYLSERYLMETHIONYLPHENYLALANYLPROLYLSERYLSERYLGLUTAMIC ACID; CANNABINOID 1 RECEPTOR; DODECYL SULFATE SODIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; PEPTIDE; UNCLASSIFIED DRUG;

ALGORITHM; ARTICLE; CARBOXY TERMINAL SEQUENCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CYTOPLASM; ELECTROSTATICS; HUMANS; IMAGING, THREE-DIMENSIONAL; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTOR, CANNABINOID, CB1;

RODENTIA;

EID: 34548386281     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2007.04.004     Document Type: Article

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