Rac-mediated macropinocytosis is a critical route for naked plasmid DNA transfer in mice

Molecular Pharmaceutics

Volumn 6, Issue 4, 2009, Pages 1170-1179

  Fumoto, Shintaro ^a   Nishi, Junya ^a   Ishii, Hiroki ^a   Wang, Xuan ^a   Miyamoto, Hirotaka ^a   Yoshikawa, Naoki ^a   Nakashima, Mikiro ^a   Nakamura, Junzo ^a   Nishida, Koyo ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Macropinocytosis; Mechanism of in vivo gene transfer; Naked plasmid DNA; Rac; Signaling pathway

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MYOSIN; PLASMID DNA; PROTEIN TYROSINE KINASE; RAC PROTEIN;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA TRANSFER; ENDOCYTOSIS; EXPERIMENTAL MOUSE; GENE TRANSFER; GENETIC TRANSFECTION; IN VIVO STUDY; MACROPINOCYTOSIS; MALE; MESOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACTINS; ANIMALS; CAVEOLAE; CLATHRIN-COATED VESICLES; DNA; ENDOCYTOSIS; GENE DOSAGE; GENE TRANSFER TECHNIQUES; IMMUNOENZYME TECHNIQUES; MALE; MICE; MUSCLE CONTRACTION; MYOSINS; P21-ACTIVATED KINASES; PINOCYTOSIS; PLASMIDS; PROTO-ONCOGENE PROTEINS C-AKT; RHO GTP-BINDING PROTEINS; SEROUS MEMBRANE; STOMACH; WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY;

EID: 68249120430     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp900042p     Document Type: Article

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