Noninvasive gene delivery to the liver by mechanical massage

Hepatology

Volumn 35, Issue 6, 2002, Pages 1314-1319

  Liu, Feng ^a   Huang, Leaf ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; GREEN FLUORESCENT PROTEIN; LIVER ENZYME; LUCIFERASE; PLASMID DNA; SCATTER FACTOR; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOMEGALOVIRUS; GENE DELIVERY SYSTEM; GENE TRANSFER; GENETIC TRANSFECTION; LIVER FAILURE; MASSAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; REPRODUCIBILITY; SAFETY; SURVIVAL RATE; TECHNIQUE; TREATMENT OUTCOME;

EID: 0036614368     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.33467     Document Type: Article

References (25)

1. Retroviral-mediated gene transfer into hepatocytes in vivo
2. Persistent gene expression after retroviral gene transfer into liver cells in vivo
3. Adenovirus-mediated in vivo gene transfer and expression in normal rat liver
4. Assessment of recombinant adenoviral vectors for hepatic gene therapy
5. Adeno-associated viral vector-mediated gene transfer results in long-term enzymatic and functional correction in multiple organs of Fabry mice
6. Gene therapy for liver diseases: Recent strategies for treatment of viral hepatitis and liver malignancies
7. Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: Cationic lipid complexes
8. Contribution of plasmid DNA to inflammation in the lung after administration of cationic lipid: pDNA complexes
9. The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo
10. Gene expression following direct injection of DNA into liver
11. 2+ flux
12. In vivo gene electroinjection and expression in rat liver
13. Direct gene transfer into rat liver cells by in vivo electroporation
14. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
15. High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
16. Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth
17. Long-term and therapeutic-level hepatic gene expression of human factor IX after naked plasmid transfer in vivo
18. Time course of gene expression after plasmid DNA gene transfer to the liver
19. Tail-vein injection of mannan-binding lectin DNA leads to high expression levels of multimeric protein in liver
20. Systemic production of IL-12 by naked DNA mediated gene transfer: Toxicity and attenuation of transgene expression in vivo
21. Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice
22. Fulminant hepatic failure: Summary of a workshop
23. A pressure-mediated nonviral method for efficient arterial gene and oligonucleotide transfer
24. Hypothesis: Naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process
25. Improving plasmid DNA-mediated liver gene transfer by prolonging its retention in the hepatic vasculature