-
1
-
-
0032538973
-
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
-
Abo A, Qu J, Cammarano MS, Dan C, Fritsch A, Baud V, Belisle B, Minden A. 1998. PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia. EMBO J 17:6527-6540.
-
(1998)
EMBO J
, vol.17
, pp. 6527-6540
-
-
Abo, A.1
Qu, J.2
Cammarano, M.S.3
Dan, C.4
Fritsch, A.5
Baud, V.6
Belisle, B.7
Minden, A.8
-
2
-
-
0028328250
-
Spreading of differentiating human monocytes is associated with a major increase in membrane-bound CDC42
-
Aepfelbacher M, Vauti F, Weber PC, Glomset JA. 1994. Spreading of differentiating human monocytes is associated with a major increase in membrane-bound CDC42. Proc Natl Acad Sci USA 91:4263-4267.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4263-4267
-
-
Aepfelbacher, M.1
Vauti, F.2
Weber, P.C.3
Glomset, J.A.4
-
3
-
-
0029786313
-
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
-
Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, Kaibuchi K. 1996b. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem 271: 20246-20249.
-
(1996)
J Biol Chem
, vol.271
, pp. 20246-20249
-
-
Amano, M.1
Ito, M.2
Kimura, K.3
Fukata, Y.4
Chihara, K.5
Nakano, T.6
Matsuura, Y.7
Kaibuchi, K.8
-
4
-
-
0345593816
-
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts
-
Angers-Loustau A, Cote JF, Charest A, Dowbenko D, Spencer S, Lasky LA, Tremblay ML. 1999. Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J Cell Biol 144:1019-1031.
-
(1999)
J Cell Biol
, vol.144
, pp. 1019-1031
-
-
Angers-Loustau, A.1
Cote, J.F.2
Charest, A.3
Dowbenko, D.4
Spencer, S.5
Lasky, L.A.6
Tremblay, M.L.7
-
5
-
-
0032565962
-
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
-
Arber S, Barbayannis FA, Hanser H, Schneider C, Stanyon CA, Bernard O, Caroni P. 1998. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393:805-809.
-
(1998)
Nature
, vol.393
, pp. 805-809
-
-
Arber, S.1
Barbayannis, F.A.2
Hanser, H.3
Schneider, C.4
Stanyon, C.A.5
Bernard, O.6
Caroni, P.7
-
6
-
-
0032476646
-
Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B
-
Arregui CO, Balsamo J, Lilien J. 1998. Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B. J Cell Biol 143:861-873.
-
(1998)
J Cell Biol
, vol.143
, pp. 861-873
-
-
Arregui, C.O.1
Balsamo, J.2
Lilien, J.3
-
7
-
-
0029680639
-
Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome
-
Aspenstrom P, Lindberg U, Hall A. 1996. Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome. Curr Biol 6:70-75.
-
(1996)
Curr Biol
, vol.6
, pp. 70-75
-
-
Aspenstrom, P.1
Lindberg, U.2
Hall, A.3
-
8
-
-
0028981365
-
Identification of a mouse p21Cdc42/Rac activated kinase
-
Bagrodia S, Taylor SJ, Creasy CL, Chernoff J, Cerione RA. 1995. Identification of a mouse p21Cdc42/Rac activated kinase. J Biol Chem 270:22731-22737.
-
(1995)
J Biol Chem
, vol.270
, pp. 22731-22737
-
-
Bagrodia, S.1
Taylor, S.J.2
Creasy, C.L.3
Chernoff, J.4
Cerione, R.A.5
-
9
-
-
0028236960
-
The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both p125FAK and protein kinase C-delta to focal adhesions
-
Barry ST, Critchley DR. 1994. The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both p125FAK and protein kinase C-delta to focal adhesions. J Cell Sci 107:1033-1045.
-
(1994)
J Cell Sci
, vol.107
, pp. 1033-1045
-
-
Barry, S.T.1
Critchley, D.R.2
-
10
-
-
0030963016
-
Requirement for Rho in integrin signalling
-
Barry ST, Flinn HM, Humphries MJ, Critchley DR, Ridley AJ. 1997. Requirement for Rho in integrin signalling. Cell Adhes Commun 4:387-398.
-
(1997)
Cell Adhes Commun
, vol.4
, pp. 387-398
-
-
Barry, S.T.1
Flinn, H.M.2
Humphries, M.J.3
Critchley, D.R.4
Ridley, A.J.5
-
11
-
-
0031281898
-
Zyxin: Zinc fingers at sites of cell adhesion
-
Beckerle MC. 1997. Zyxin: zinc fingers at sites of cell adhesion. Bioessays 19:949-957.
-
(1997)
Bioessays
, vol.19
, pp. 949-957
-
-
Beckerle, M.C.1
-
12
-
-
0032411699
-
Spatial control of actin filament assembly: Lessons from Listeria
-
Beckerle MC. 1998. Spatial control of actin filament assembly: lessons from Listeria. Cell 95:741-748.
-
(1998)
Cell
, vol.95
, pp. 741-748
-
-
Beckerle, M.C.1
-
13
-
-
0029146869
-
An examination of focal adhesion formation and tyrosine phosphorylation in fibroblasts isolated from src-, fyn- and yes- mice
-
Bockholt SM, Burridge K. 1995. An examination of focal adhesion formation and tyrosine phosphorylation in fibroblasts isolated from src-, fyn- and yes- mice. Cell Adhes Commun 3:91-100.
-
(1995)
Cell Adhes Commun
, vol.3
, pp. 91-100
-
-
Bockholt, S.M.1
Burridge, K.2
-
14
-
-
0024150623
-
Focal adhesions: Transmembrane junctions between the extracellular matrix and the cytoskeleton
-
Burridge K, Fath K, Kelly T, Nuckolls G, Turner C. 1988. Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu Rev Cell Biol 4:487-525.
-
(1988)
Annu Rev Cell Biol
, vol.4
, pp. 487-525
-
-
Burridge, K.1
Fath, K.2
Kelly, T.3
Nuckolls, G.4
Turner, C.5
-
15
-
-
0026445719
-
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix, a role in cytoskeletal assembly
-
Burridge K, Turner C, Romer L. 1992. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix, a role in cytoskeletal assembly. J Cell Biol 119:893-904.
-
(1992)
J Cell Biol
, vol.119
, pp. 893-904
-
-
Burridge, K.1
Turner, C.2
Romer, L.3
-
16
-
-
0033555070
-
Focal adhesion kinase in integrin-mediated signaling
-
Cary LA, Guan JL. 1999. Focal adhesion kinase in integrin-mediated signaling. Front Biosci 15;4:D102-113.
-
(1999)
Front Biosci
, vol.15
, Issue.4
-
-
Cary, L.A.1
Guan, J.L.2
-
17
-
-
0029948080
-
Stimulation of cells migration by overexpression of focal adhesion kinase and its association with Src and Fyn
-
Cary LA, Chang JF, Guan JL. 1996. Stimulation of cells migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J Cell Sci 109:1787-1794.
-
(1996)
J Cell Sci
, vol.109
, pp. 1787-1794
-
-
Cary, L.A.1
Chang, J.F.2
Guan, J.L.3
-
18
-
-
0032509565
-
Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration
-
Cary LA, Han DC, Polte TR, Hanks SK, Guan JL. 1998. Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration. J Cell Biol 140:211-221.
-
(1998)
J Cell Biol
, vol.140
, pp. 211-221
-
-
Cary, L.A.1
Han, D.C.2
Polte, T.R.3
Hanks, S.K.4
Guan, J.L.5
-
19
-
-
0027477350
-
Fibronectin cell-binding domain triggered transmembrane signal transduction in human monocytes
-
Chang ZL, Beezhold DH, Personius CD, Shen ZL. 1993. Fibronectin cell-binding domain triggered transmembrane signal transduction in human monocytes. J Leukoc Biol 53:79-85.
-
(1993)
J Leukoc Biol
, vol.53
, pp. 79-85
-
-
Chang, Z.L.1
Beezhold, D.H.2
Personius, C.D.3
Shen, Z.L.4
-
20
-
-
0029046858
-
Interaction of focal adhesion kinase with cytoskeletal protein talin
-
Chen HC, Appeddu PA, Parsons JT, Hildebrand JD, Schaller MD, Guan JL. 1995. Interaction of focal adhesion kinase with cytoskeletal protein talin. J Biol Chem 270:16995-16999.
-
(1995)
J Biol Chem
, vol.270
, pp. 16995-16999
-
-
Chen, H.C.1
Appeddu, P.A.2
Parsons, J.T.3
Hildebrand, J.D.4
Schaller, M.D.5
Guan, J.L.6
-
22
-
-
0028036684
-
The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
-
Chong LD, Traynor-Kaplan A, Bokoch GM, Schwartz MA. 1994. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79:507-513.
-
(1994)
Cell
, vol.79
, pp. 507-513
-
-
Chong, L.D.1
Traynor-Kaplan, A.2
Bokoch, G.M.3
Schwartz, M.A.4
-
23
-
-
0028557424
-
Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation
-
Chrzanowska-Wodnicka M, Burridge K. 1994. Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation. J Cell Sci 107:3643-3654.
-
(1994)
J Cell Sci
, vol.107
, pp. 3643-3654
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
24
-
-
0029995797
-
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
-
Chrzanowska-Wodnicka M, Burridge K. 1996. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol 133:1403-1415.
-
(1996)
J Cell Biol
, vol.133
, pp. 1403-1415
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
25
-
-
15844388825
-
Differential translocation of protein kinase C epsilon during HeLa cell adhesion to a gelatin substratum
-
Chun JS, Ha MJ, Jacobson BS. 1996. Differential translocation of protein kinase C epsilon during HeLa cell adhesion to a gelatin substratum. J Biol Chem 271:13008-13012.
-
(1996)
J Biol Chem
, vol.271
, pp. 13008-13012
-
-
Chun, J.S.1
Ha, M.J.2
Jacobson, B.S.3
-
26
-
-
0028987936
-
Integrins and signal transduction pathways: The road taken
-
Clark EA, Brugge JS. 1995. Integrins and signal transduction pathways: the road taken. Science 268:233-239.
-
(1995)
Science
, vol.268
, pp. 233-239
-
-
Clark, E.A.1
Brugge, J.S.2
-
27
-
-
0032572557
-
Integrin-mediated signals regulated by members of the rho family of GTPases
-
Clark EA, King WG, Brugge JS, Symons M, Hynes RO. 1998. Integrin-mediated signals regulated by members of the rho family of GTPases. J Cell Biol 142:573-586.
-
(1998)
J Cell Biol
, vol.142
, pp. 573-586
-
-
Clark, E.A.1
King, W.G.2
Brugge, J.S.3
Symons, M.4
Hynes, R.O.5
-
28
-
-
0028173980
-
Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK
-
Cobb BS, Schaller MD, Leu TH, Parsons JT. 1994. Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK. Mol Cell Biol 14:147-155.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 147-155
-
-
Cobb, B.S.1
Schaller, M.D.2
Leu, T.H.3
Parsons, J.T.4
-
29
-
-
0027333420
-
Life at the leading edge
-
Condeelis J. 1993. Life at the leading edge. Annu Rev Cell Biol 9:411-444.
-
(1993)
Annu Rev Cell Biol
, vol.9
, pp. 411-444
-
-
Condeelis, J.1
-
30
-
-
0031033292
-
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
-
Crespo P, Schuebel KE, Ostrom AA, Gutkind JS, Bustelo XR. 1997. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature 385:169-172.
-
(1997)
Nature
, vol.385
, pp. 169-172
-
-
Crespo, P.1
Schuebel, K.E.2
Ostrom, A.A.3
Gutkind, J.S.4
Bustelo, X.R.5
-
31
-
-
0028237367
-
Integrin-mediated signal transduction in human endothelial cells: Analysis of tyrosine phosphorylation events
-
Defilippi P, Bozzo C, Volpe G, Romano G, Venturino M, Silengo L, Tarone G. 1994. Integrin-mediated signal transduction in human endothelial cells: analysis of tyrosine phosphorylation events. Cell Adhes Commun 2:75-86.
-
(1994)
Cell Adhes Commun
, vol.2
, pp. 75-86
-
-
Defilippi, P.1
Bozzo, C.2
Volpe, G.3
Romano, G.4
Venturino, M.5
Silengo, L.6
Tarone, G.7
-
32
-
-
0028792065
-
p125FAK tyrosine phosphorylation and focal adhesion assembly, studies with phosphotyrosine phosphatase inhibitors
-
Defilippi P, Retta F S, Olivo C, Palmieri M, Venturino M, Silengo L, Tarone G. 1995. p125FAK tyrosine phosphorylation and focal adhesion assembly, studies with phosphotyrosine phosphatase inhibitors. Exp Cell Res 221:141-152.
-
(1995)
Exp Cell Res
, vol.221
, pp. 141-152
-
-
Defilippi, P.1
Retta, F.S.2
Olivo, C.3
Palmieri, M.4
Venturino, M.5
Silengo, L.6
Tarone, G.7
-
34
-
-
0030845282
-
Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly, involvement of protein kinase C, RhoGTPase and tyrosine phosphorylation
-
Defilippi P, Venturino M, Volpe G, Palmieri M, Gulino D, Duperrey A, Boquet P, Fiorentini C, Silengo, L, Tarone G. 1997b. Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly, involvement of protein kinase C, RhoGTPase and tyrosine phosphorylation. J Biol Chem 272:21726-21734.
-
(1997)
J Biol Chem
, vol.272
, pp. 21726-21734
-
-
Defilippi, P.1
Venturino, M.2
Volpe, G.3
Palmieri, M.4
Gulino, D.5
Duperrey, A.6
Boquet, P.7
Fiorentini, C.8
Silengo, L.9
Tarone, G.10
-
35
-
-
0030929154
-
Actin cytoskeleton polymerization in Dbl-transformed NIH/3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins
-
Defilippi P, Olivo C, Tarone G, Mancini P, Torrisi MR, Eva A. 1997c. Actin cytoskeleton polymerization in Dbl-transformed NIH/3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins. Oncogene 14:1933-1943
-
(1997)
Oncogene
, vol.14
, pp. 1933-1943
-
-
Defilippi, P.1
Olivo, C.2
Tarone, G.3
Mancini, P.4
Torrisi, M.R.5
Eva, A.6
-
36
-
-
0029075648
-
WASP gene mutations in Wiskott-Aldrich syndrome and X-linked thrombocytopenia
-
Derry JM, Kerns JA, Weinberg KI, Ochs HD, Volpini V, Estivill X, Walker AP, Francke U. 1995. WASP gene mutations in Wiskott-Aldrich syndrome and X-linked thrombocytopenia. Hum Mol Genet 4:1127-1135.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 1127-1135
-
-
Derry, J.M.1
Kerns, J.A.2
Weinberg, K.I.3
Ochs, H.D.4
Volpini, V.5
Estivill, X.6
Walker, A.P.7
Francke, U.8
-
37
-
-
0032491424
-
Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron
-
Di Cunto F, Calautti E, Hsiao J, Ong L, Topley G, Turco E, Dotto GP. 1998. Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron. J Biol Chem 273:29706-29711.
-
(1998)
J Biol Chem
, vol.273
, pp. 29706-29711
-
-
Di Cunto, F.1
Calautti, E.2
Hsiao, J.3
Ong, L.4
Topley, G.5
Turco, E.6
Dotto, G.P.7
-
38
-
-
0028918391
-
Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK
-
Eide BL, Turck CW, Escobedo JA. 1995. Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK. Mol Cell Biol 15:2819-2827.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2819-2827
-
-
Eide, B.L.1
Turck, C.W.2
Escobedo, J.A.3
-
39
-
-
0029892628
-
Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin
-
Flinn HM, Ridley AJ. 1996. Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin. J Cell Sci 109:1133-1141.
-
(1996)
J Cell Sci
, vol.109
, pp. 1133-1141
-
-
Flinn, H.M.1
Ridley, A.J.2
-
40
-
-
0033524928
-
Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST
-
Garton AJ, Tonks NK. 1999. Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST. J Biol Chem 274:3811-3818.
-
(1999)
J Biol Chem
, vol.274
, pp. 3811-3818
-
-
Garton, A.J.1
Tonks, N.K.2
-
41
-
-
0030753474
-
Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition
-
Garton AJ, Burnham MR, Bouton AH, Tonks NK. 1997. Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition. Oncogene 15: 877-885.
-
(1997)
Oncogene
, vol.15
, pp. 877-885
-
-
Garton, A.J.1
Burnham, M.R.2
Bouton, A.H.3
Tonks, N.K.4
-
42
-
-
0028018234
-
Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture
-
Gates RE, King LE Jr, Hanks SK, Nanney LB. 1994. Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture. Cell Growth Differ 5:891-899.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 891-899
-
-
Gates, R.E.1
King L.E., Jr.2
Hanks, S.K.3
Nanney, L.B.4
-
43
-
-
0031657476
-
Control of cytoskeletal architecture by the src-suppressed C kinase substrate, SSeCKS
-
Gelman IH, Lee K, Tombler E, Gordon R, Lin X. 1998. Control of cytoskeletal architecture by the src-suppressed C kinase substrate, SSeCKS. Cell Motil Cytoskeleton 41:1-17.
-
(1998)
Cell Motil Cytoskeleton
, vol.41
, pp. 1-17
-
-
Gelman, I.H.1
Lee, K.2
Tombler, E.3
Gordon, R.4
Lin, X.5
-
44
-
-
0030592559
-
Mena, a relative of VASP and Drosophila enabled, is implicated in the control of microfilament dynamics
-
Gertler FB, Niebuhr K, Reinhard M, Wehland J, Soriano P. 1996. Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell 87:227-239.
-
(1996)
Cell
, vol.87
, pp. 227-239
-
-
Gertler, F.B.1
Niebuhr, K.2
Reinhard, M.3
Wehland, J.4
Soriano, P.5
-
45
-
-
0029943112
-
Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate
-
Gilmore AP, Burridge K. 1996. Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate. Nature 381: 531-535.
-
(1996)
Nature
, vol.381
, pp. 531-535
-
-
Gilmore, A.P.1
Burridge, K.2
-
46
-
-
0029741102
-
Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
-
Gilmore AP, Romer LH. 1996. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol Biol Cell 7:1209-1224.
-
(1996)
Mol Biol Cell
, vol.7
, pp. 1209-1224
-
-
Gilmore, A.P.1
Romer, L.H.2
-
47
-
-
0028951464
-
Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase
-
Guinebault C, Payrastre B, Racaud-Sultan C, Mazarguil H, Breton M, Mauco G, Plantavid M, Chap H. 1995. Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase. J Cell Biol 129:831-842.
-
(1995)
J Cell Biol
, vol.129
, pp. 831-842
-
-
Guinebault, C.1
Payrastre, B.2
Racaud-Sultan, C.3
Mazarguil, H.4
Breton, M.5
Mauco, G.6
Plantavid, M.7
Chap, H.8
-
48
-
-
0030032942
-
Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen
-
Haimovich B, Kaneshiki N, Ping J. 1996. Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen. Blood 87:152-161.
-
(1996)
Blood
, vol.87
, pp. 152-161
-
-
Haimovich, B.1
Kaneshiki, N.2
Ping, J.3
-
49
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A. 1998. Rho GTPases and the actin cytoskeleton. Science 279:509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
50
-
-
0030585376
-
Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas
-
Hamasaki K, Mimura T, Morino N, Furuya H, Nakamoto T, Aizawa S, Morimoto C, Yazaki Y, Hirai H, Nojima Y. 1996. Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas. Biochem Biophys Res Commun 222:338-343.
-
(1996)
Biochem Biophys Res Commun
, vol.222
, pp. 338-343
-
-
Hamasaki, K.1
Mimura, T.2
Morino, N.3
Furuya, H.4
Nakamoto, T.5
Aizawa, S.6
Morimoto, C.7
Yazaki, Y.8
Hirai, H.9
Nojima, Y.10
-
51
-
-
15144353776
-
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
-
Han J, Luby-Phelps K, Das B, Shu X, Xia Y, Mosteller RD, Krishna UM, Falck JR, White MA, Broek D. 1998. Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science 279:558-560.
-
(1998)
Science
, vol.279
, pp. 558-560
-
-
Han, J.1
Luby-Phelps, K.2
Das, B.3
Shu, X.4
Xia, Y.5
Mosteller, R.D.6
Krishna, U.M.7
Falck, J.R.8
White, M.A.9
Broek, D.10
-
52
-
-
0027958423
-
Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
-
Hart MJ, Eva A, Zangrilli D, Aaronson SA, Evans T, Cerione RA, Zheng Y. 1994. Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J Biol Chem 269:62-65.
-
(1994)
J Biol Chem
, vol.269
, pp. 62-65
-
-
Hart, M.J.1
Eva, A.2
Zangrilli, D.3
Aaronson, S.A.4
Evans, T.5
Cerione, R.A.6
Zheng, Y.7
-
53
-
-
0029666251
-
p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase
-
Harte MT, Hildebrand JD, Burnham MR, Bouton AH, Parsons JT. 1996. p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase. J Biol Chem 271:13649-13655.
-
(1996)
J Biol Chem
, vol.271
, pp. 13649-13655
-
-
Harte, M.T.1
Hildebrand, J.D.2
Burnham, M.R.3
Bouton, A.H.4
Parsons, J.T.5
-
54
-
-
0031720629
-
Integrin associated proteins
-
Hemler ME. 1998. Integrin associated proteins. Curr Opin Cell Biol 10:578-585.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 578-585
-
-
Hemler, M.E.1
-
55
-
-
0029055784
-
Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase
-
Hildebrand JD, Schaller MD, Parsons JT. 1995. Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase. Mol Biol Cell 6:637-647.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 637-647
-
-
Hildebrand, J.D.1
Schaller, M.D.2
Parsons, J.T.3
-
56
-
-
0029955660
-
An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
-
Hildebrand JD, Taylor JM, Parsons JT. 1996. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol Cell Biol 16:3169-3178.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3169-3178
-
-
Hildebrand, J.D.1
Taylor, J.M.2
Parsons, J.T.3
-
59
-
-
0026770377
-
Integrins: Versatility, modulation and signaling in cell adhesion
-
Hynes RO. 1992. Integrins: versatility, modulation and signaling in cell adhesion. Cell 69:11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
60
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
Ilic D, Furuta Y, Kanazawa S, Takeda N, Sobue K, Nakatsuji N, Omura S, Fujimoto J, Okada M, Yamamoto T, et al. 1995. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377:539-544.
-
(1995)
Nature
, vol.377
, pp. 539-544
-
-
Ilic, D.1
Furuta, Y.2
Kanazawa, S.3
Takeda, N.4
Sobue, K.5
Nakatsuji, N.6
Omura, S.7
Fujimoto, J.8
Okada, M.9
Yamamoto, T.10
-
61
-
-
13344270369
-
The molecular architecture of focal adhesions
-
Jockusch BM, Bubeck P, Giehl K, Kroemker M, Moschner J, Rothkegel M, Rudiger M, Schluter K, Stanke G, Winkler J. 1995. The molecular architecture of focal adhesions. Annu Rev Cell Dev Biol 11:379-416.
-
(1995)
Annu Rev Cell Dev Biol
, vol.11
, pp. 379-416
-
-
Jockusch, B.M.1
Bubeck, P.2
Giehl, K.3
Kroemker, M.4
Moschner, J.5
Rothkegel, M.6
Rudiger, M.7
Schluter, K.8
Stanke, G.9
Winkler, J.10
-
62
-
-
0028836195
-
F-actin binding site masked by the intramolecular association of vinculin head and tail domains
-
Johnson RP, Craig SW. 1995. F-actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 373:261-264.
-
(1995)
Nature
, vol.373
, pp. 261-264
-
-
Johnson, R.P.1
Craig, S.W.2
-
63
-
-
0028151515
-
Association of the amino/terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527
-
Kaplan KB, Bibbins KE, Swedlow JR, Arnaud M, Morgan DO, Varmus HE. 1994. Association of the amino/terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO J 13:4745-4756.
-
(1994)
EMBO J
, vol.13
, pp. 4745-4756
-
-
Kaplan, K.B.1
Bibbins, K.E.2
Swedlow, J.R.3
Arnaud, M.4
Morgan, D.O.5
Varmus, H.E.6
-
64
-
-
0029034939
-
C-Src enhances the spreading of Src-/Src-fibroblasts on fibronectin by kinase-independent mechanisms
-
Kaplan KB, Swedlow JR, Morgan DO, Varmus HE. 1995. c-Src enhances the spreading of Src-/Src-fibroblasts on fibronectin by kinase-independent mechanisms. Genes Dev 9:1505-1517.
-
(1995)
Genes Dev
, vol.9
, pp. 1505-1517
-
-
Kaplan, K.B.1
Swedlow, J.R.2
Morgan, D.O.3
Varmus, H.E.4
-
65
-
-
0031459917
-
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K
-
Keely PJ, Westwick JK, Whitehead IP, Der CJ, Parise LV. 1997. Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature 390:632-636.
-
(1997)
Nature
, vol.390
, pp. 632-636
-
-
Keely, P.J.1
Westwick, J.K.2
Whitehead, I.P.3
Der, C.J.4
Parise, L.V.5
-
66
-
-
0032030656
-
Integrins and GTPases in tumour cell growth, motility and invasion
-
Keely P, Parise L, Juliano R. 1998. Integrins and GTPases in tumour cell growth, motility and invasion. Trends Cell Biol 8:101-106.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 101-106
-
-
Keely, P.1
Parise, L.2
Juliano, R.3
-
67
-
-
0022893107
-
Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome
-
Kenney D, Caims L, Remold-O'Donnell E, Peterson J, Rosen FS, Parkman R. 1986. Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome. Blood 68:1329-1332.
-
(1986)
Blood
, vol.68
, pp. 1329-1332
-
-
Kenney, D.1
Caims, L.2
Remold-O'donnell, E.3
Peterson, J.4
Rosen, F.S.5
Parkman, R.6
-
68
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
-
Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. 1996. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273:245-248.
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Chihara, K.4
Fukata, Y.5
Nakafuku, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
Iwamatsu, A.11
Kaibuchi, K.12
-
69
-
-
0032544426
-
Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex
-
Kiyokawa E, Hashimoto Y, Kurata T, Sugimura H, Matsuda M. 1998a. Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex. J Biol Chem 273:24479-24484.
-
(1998)
J Biol Chem
, vol.273
, pp. 24479-24484
-
-
Kiyokawa, E.1
Hashimoto, Y.2
Kurata, T.3
Sugimura, H.4
Matsuda, M.5
-
70
-
-
0032213110
-
Activation of Rac1 by a Crk SH3-binding protein, DOCK180
-
Kiyokawa E, Hashimoto Y, Kobayashi S, Sugimura H, Kurata T, Matsuda M. 1998b. Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev 12:3331-3336.
-
(1998)
Genes Dev
, vol.12
, pp. 3331-3336
-
-
Kiyokawa, E.1
Hashimoto, Y.2
Kobayashi, S.3
Sugimura, H.4
Kurata, T.5
Matsuda, M.6
-
71
-
-
0029953158
-
Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42
-
Kolluri R, Fuchs Tolias K, Carpenter CL, Rosen FS, Kirchhausen T. 1996. Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42. Proc Natl Acad Sci USA 93:5615-5618.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5615-5618
-
-
Kolluri, R.1
Fuchs Tolias, K.2
Carpenter, C.L.3
Rosen, F.S.4
Kirchhausen, T.5
-
72
-
-
0029789678
-
The p160 Roka is a member of a kinase family and is involved in the reorganization of the cytoskeleton
-
Leung T, Chen XQ, Manser E, Lim L. 1996. The p160 Roka is a member of a kinase family and is involved in the reorganization of the cytoskeleton. Mol Cell Biol 16:5313-5327.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5313-5327
-
-
Leung, T.1
Chen, X.Q.2
Manser, E.3
Lim, L.4
-
73
-
-
17544378105
-
Role of MacMARCKS in integrin-dependent macrophage spreading and tyrosine phosphorylation of paxillin
-
Li J, Zhu Z, Bao Z. 1996. Role of MacMARCKS in integrin-dependent macrophage spreading and tyrosine phosphorylation of paxillin. J Biol Chem 271:12985-12990.
-
(1996)
J Biol Chem
, vol.271
, pp. 12985-12990
-
-
Li, J.1
Zhu, Z.2
Bao, Z.3
-
74
-
-
0030756973
-
Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization
-
Machesky LM, Hall A. 1997. Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization. J Cell Biol 138:913-926.
-
(1997)
J Cell Biol
, vol.138
, pp. 913-926
-
-
Machesky, L.M.1
Hall, A.2
-
75
-
-
0029559573
-
A novel partner for the GTP-bound forms of rho and rac
-
Madaule P, Furuyashiki T, Reid T, Ishizaki T, Watanabe G, Morii N, Narumiya S. 1995. A novel partner for the GTP-bound forms of rho and rac. FEBS Lett 377:243-248.
-
(1995)
FEBS Lett
, vol.377
, pp. 243-248
-
-
Madaule, P.1
Furuyashiki, T.2
Reid, T.3
Ishizaki, T.4
Watanabe, G.5
Morii, N.6
Narumiya, S.7
-
76
-
-
0032581530
-
Role of citron kinase as a target of the small GTPase Rho in cytokinesis
-
Madaule P, Eda M, Watanabe N, Fujisawa K, Matsuoka T, Bito H, Ishizaki T, Narumiya S. 1998. Role of citron kinase as a target of the small GTPase Rho in cytokinesis. Nature 394:491-494.
-
(1998)
Nature
, vol.394
, pp. 491-494
-
-
Madaule, P.1
Eda, M.2
Watanabe, N.3
Fujisawa, K.4
Matsuoka, T.5
Bito, H.6
Ishizaki, T.7
Narumiya, S.8
-
77
-
-
0028078824
-
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
-
Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L. 1994. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367:40-46.
-
(1994)
Nature
, vol.367
, pp. 40-46
-
-
Manser, E.1
Leung, T.2
Salihuddin, H.3
Zhao, Z.S.4
Lim, L.5
-
78
-
-
0028862297
-
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
-
Manser E, Chong C, Zhao ZS, Leung T, Michael G, Hall C, Lim L. 1995. Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family. J Biol Chem 270:25070-25078.
-
(1995)
J Biol Chem
, vol.270
, pp. 25070-25078
-
-
Manser, E.1
Chong, C.2
Zhao, Z.S.3
Leung, T.4
Michael, G.5
Hall, C.6
Lim, L.7
-
79
-
-
0029056399
-
A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20
-
Martin GA, Bollag G, McCormick F, Abo A. 1995. A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. EMBO J 14:1970-1978.
-
(1995)
EMBO J
, vol.14
, pp. 1970-1978
-
-
Martin, G.A.1
Bollag, G.2
McCormick, F.3
Abo, A.4
-
80
-
-
0026686182
-
Two species of human CRK cDNA encode proteins with distinct biological activities
-
Matsuda M, Tanaka S, Nagata S, Kojima A, Kurata T, Shibuya M. 1992. Two species of human CRK cDNA encode proteins with distinct biological activities. Mol Cell Biol 12:3482-3489.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3482-3489
-
-
Matsuda, M.1
Tanaka, S.2
Nagata, S.3
Kojima, A.4
Kurata, T.5
Shibuya, M.6
-
81
-
-
9244257348
-
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
-
Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. 1996. Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J 15:2208-2216.
-
(1996)
EMBO J
, vol.15
, pp. 2208-2216
-
-
Matsui, T.1
Amano, M.2
Yamamoto, T.3
Chihara, K.4
Nakafuku, M.5
Ito, M.6
Nakano, T.7
Okawa, K.8
Iwamatsu, A.9
Kaibuchi, K.10
-
82
-
-
0027296039
-
The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion
-
McGlade J, Brunkhorst B, Anderson D, Mbamalu G, Settleman J, Dedhar S, Rozakis-Adcock M, Chen LB, Pawson T. 1993. The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion. EMBO J 12:3073-3081.
-
(1993)
EMBO J
, vol.12
, pp. 3073-3081
-
-
McGlade, J.1
Brunkhorst, B.2
Anderson, D.3
Mbamalu, G.4
Settleman, J.5
Dedhar, S.6
Rozakis-Adcock, M.7
Chen, L.B.8
Pawson, T.9
-
83
-
-
0027176804
-
Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown
-
McNamee HP, Ingber DE, Schwartz MA. 1993. Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown. J Cell Biol 121:673-678.
-
(1993)
J Cell Biol
, vol.121
, pp. 673-678
-
-
McNamee, H.P.1
Ingber, D.E.2
Schwartz, M.A.3
-
84
-
-
0031952518
-
Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP
-
Miki H, Sasaki T, Takai Y, Takenawa T. 1998. Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP. Nature 391:93-96.
-
(1998)
Nature
, vol.391
, pp. 93-96
-
-
Miki, H.1
Sasaki, T.2
Takai, Y.3
Takenawa, T.4
-
85
-
-
0032481142
-
Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vavl
-
Miranti CK, Leng L, Maschberger P, Brugge JS, Shattil SJ. 1998. Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vavl. Curr Biol 8:1289-1299.
-
(1998)
Curr Biol
, vol.8
, pp. 1289-1299
-
-
Miranti, C.K.1
Leng, L.2
Maschberger, P.3
Brugge, J.S.4
Shattil, S.J.5
-
86
-
-
0030049170
-
Actin-based cell motility and cell locomotion
-
Mitchinson TJ, Cramer LP. 1996. Actin-based cell motility and cell locomotion. Cell 84:371-379.
-
(1996)
Cell
, vol.84
, pp. 371-379
-
-
Mitchinson, T.J.1
Cramer, L.P.2
-
87
-
-
0026731846
-
T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome
-
Molina IJ, Kenney DM, Rosen FS, Remold-O'Donnell E. 1992. T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome. J Exp Med 176:867-874.
-
(1992)
J Exp Med
, vol.176
, pp. 867-874
-
-
Molina, I.J.1
Kenney, D.M.2
Rosen, F.S.3
Remold-O'Donnell, E.4
-
88
-
-
0032538798
-
Integrins induce activation of EGF receptor: Role in MAP kinase induction and adhesion-dependent cell survival
-
Moro L, Venturino M, Bozzo C, Silengo L, Altruda F, Beguinot L, Tarone G, Defilippi P. 1998. Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival. EMBO J 17:6622-6632.
-
(1998)
EMBO J
, vol.17
, pp. 6622-6632
-
-
Moro, L.1
Venturino, M.2
Bozzo, C.3
Silengo, L.4
Altruda, F.5
Beguinot, L.6
Tarone, G.7
Defilippi, P.8
-
89
-
-
0030612748
-
Rho effectors and reorganization of actin cytoskeleton
-
Narumiya S, Ishizaki T, Watanabe N. 1997. Rho effectors and reorganization of actin cytoskeleton. FEBS Lett 410:68-72.
-
(1997)
FEBS Lett
, vol.410
, pp. 68-72
-
-
Narumiya, S.1
Ishizaki, T.2
Watanabe, N.3
-
90
-
-
0032559211
-
Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos
-
Nimnual AS, Yatsula BA, Bar-Sagi D. 1998. Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos. Science 279:560-3.
-
(1998)
Science
, vol.279
, pp. 560-563
-
-
Nimnual, A.S.1
Yatsula, B.A.2
Bar-Sagi, D.3
-
91
-
-
0029034873
-
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs
-
Nojima Y, Noritsugo M, Mimura T, Hamasaki K, Furuya H, Sakai R, Sato T, Tachibana K, Morimoto C, Yazaki Y, Hirai H. 1995b. Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs. J Biol Chem 270:15398-15402.
-
(1995)
J Biol Chem
, vol.270
, pp. 15398-15402
-
-
Nojima, Y.1
Noritsugo, M.2
Mimura, T.3
Hamasaki, K.4
Furuya, H.5
Sakai, R.6
Sato, T.7
Tachibana, K.8
Morimoto, C.9
Yazaki, Y.10
Hirai, H.11
-
92
-
-
0032213953
-
Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes
-
Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J. 1998. Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Genes Dev 2:3337-3342.
-
(1998)
Genes Dev
, vol.2
, pp. 3337-3342
-
-
Nolan, K.M.1
Barrett, K.2
Lu, Y.3
Hu, K.Q.4
Vincent, S.5
Settleman, J.6
-
93
-
-
0032576583
-
ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts
-
Norman JC, Jones D, Barry ST, Holt MR, Cockcroft S, Critchley DR. 1998. ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts. J Cell Biol 143:1981-1995.
-
(1998)
J Cell Biol
, vol.143
, pp. 1981-1995
-
-
Norman, J.C.1
Jones, D.2
Barry, S.T.3
Holt, M.R.4
Cockcroft, S.5
Critchley, D.R.6
-
94
-
-
0018834588
-
The Wiskott-Aldrich syndrome: Studies of lymphocytes, granulocytes, and platelets
-
Ochs HD, Slichter SJ, Harker LA, Von Behrens WE, Clark RA, Wedgwood RJ. 1980. The Wiskott-Aldrich syndrome: studies of lymphocytes, granulocytes, and platelets. Blood 55:243-252.
-
(1980)
Blood
, vol.55
, pp. 243-252
-
-
Ochs, H.D.1
Slichter, S.J.2
Harker, L.A.3
Von Behrens, W.E.4
Clark, R.A.5
Wedgwood, R.J.6
-
95
-
-
0030889054
-
Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C
-
Oh ES, Woods A, Couchman JR. 1997. Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C. J Biol Chem 272:8133-8136.
-
(1997)
J Biol Chem
, vol.272
, pp. 8133-8136
-
-
Oh, E.S.1
Woods, A.2
Couchman, J.R.3
-
96
-
-
0029666080
-
pp125FAK in the focal adhesion
-
Otey CA. 1996. pp125FAK in the focal adhesion. Int Rev Cytol 167:161-183.
-
(1996)
Int Rev Cytol
, vol.167
, pp. 161-183
-
-
Otey, C.A.1
-
97
-
-
0027454485
-
Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain
-
Otey CA, Vasquez GB, Burridge K, Erickson BW. 1993. Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain. J Biol Chem 268:21193-21197.
-
(1993)
J Biol Chem
, vol.268
, pp. 21193-21197
-
-
Otey, C.A.1
Vasquez, G.B.2
Burridge, K.3
Erickson, B.W.4
-
98
-
-
0029063584
-
Rac mediates growth factor-induced arachidonic acid release
-
Peppelenbosch MP, Qiu RG, de Vries-Smits AM, Tertoolen LG, de Laat SW, McCormick F, Hall A, Symons MH, Bos JL. 1995. Rac mediates growth factor-induced arachidonic acid release. Cell 81:849-856.
-
(1995)
Cell
, vol.81
, pp. 849-856
-
-
Peppelenbosch, M.P.1
Qiu, R.G.2
De Vries-Smits, A.M.3
Tertoolen, L.G.4
De Laat, S.W.5
McCormick, F.6
Hall, A.7
Symons, M.H.8
Bos, J.L.9
-
99
-
-
0031844821
-
Activation of Rac and Cdc42 by integrins mediates cell spreading
-
Price LS, Leng J, Schwartz MA, Bokoch GM. 1998. Activation of Rac and Cdc42 by integrins mediates cell spreading. Mol Biol Cell 9:1863-1871.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 1863-1871
-
-
Price, L.S.1
Leng, J.2
Schwartz, M.A.3
Bokoch, G.M.4
-
100
-
-
0031283128
-
The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures
-
Rabinovitz I, Mercurio AM. 1997. The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures. J Cell Biol 139:1873-1884.
-
(1997)
J Cell Biol
, vol.139
, pp. 1873-1884
-
-
Rabinovitz, I.1
Mercurio, A.M.2
-
101
-
-
0031446340
-
WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells
-
Ramesh N, Anton IM, Hartwig JH, Geha RS. 1997. WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells. Proc Natl Acad Sci USA 94:14671-14676.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14671-14676
-
-
Ramesh, N.1
Anton, I.M.2
Hartwig, J.H.3
Geha, R.S.4
-
103
-
-
0029025248
-
The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins
-
Reinhard M, Giehl K, Abel K, Haffner C, Jarchau T, Hoppe V, Jockusch BM, Walter U. 1995. The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins. EMBO J 14:1583-1589.
-
(1995)
EMBO J
, vol.14
, pp. 1583-1589
-
-
Reinhard, M.1
Giehl, K.2
Abel, K.3
Haffner, C.4
Jarchau, T.5
Hoppe, V.6
Jockusch, B.M.7
Walter, U.8
-
104
-
-
0031932924
-
Regulation of inositol lipid kinases by Rho and Rac
-
Ren XD, Schwartz MA. 1998. Regulation of inositol lipid kinases by Rho and Rac. Curr Opin Genet Dev 8:63-67.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 63-67
-
-
Ren, X.D.1
Schwartz, M.A.2
-
105
-
-
0029828456
-
Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase
-
Renshaw MW, Toksoz D, Schwartz MA. 1996. Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase. J Biol Chem 271:21691-21694.
-
(1996)
J Biol Chem
, vol.271
, pp. 21691-21694
-
-
Renshaw, M.W.1
Toksoz, D.2
Schwartz, M.A.3
-
106
-
-
0030589481
-
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity
-
Retta SF, Barry ST, Critchley DR, Defilippi P, Silengo L, Tarone G. 1996. Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. Exp Cell Res 229:307-317.
-
(1996)
Exp Cell Res
, vol.229
, pp. 307-317
-
-
Retta, S.F.1
Barry, S.T.2
Critchley, D.R.3
Defilippi, P.4
Silengo, L.5
Tarone, G.6
-
107
-
-
0029971297
-
A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK
-
Richardson A, Parsons T. 1996. A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK. Nature 380:538-540.
-
(1996)
Nature
, vol.380
, pp. 538-540
-
-
Richardson, A.1
Parsons, T.2
-
108
-
-
0028331263
-
Tyrosine kinase activity, cytoskeletal organization and motility in human vascular endothelial cells
-
Romer LH, McLean N, Turner CE, Burridge K. 1994. Tyrosine kinase activity, cytoskeletal organization and motility in human vascular endothelial cells. Mol Biol Cell 6:349-361.
-
(1994)
Mol Biol Cell
, vol.6
, pp. 349-361
-
-
Romer, L.H.1
McLean, N.2
Turner, C.E.3
Burridge, K.4
-
109
-
-
0032583205
-
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
-
Sander EE, van Delft S, ten Klooster JP, Reid T, van der Kammen RA, Michiels F, Collard JG. 1998. Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J Cell Biol 143:1385-1398.
-
(1998)
J Cell Biol
, vol.143
, pp. 1385-1398
-
-
Sander, E.E.1
Van Delft, S.2
Ten Klooster, J.P.3
Reid, T.4
Van Der Kammen, R.A.5
Michiels, F.6
Collard, J.G.7
-
111
-
-
0029087478
-
Modulation of cell spreading and migration by pp125FAK phosphorylation
-
Sankar S, Mahooti-Brooks N, Hu G, Madri JA. 1995. Modulation of cell spreading and migration by pp125FAK phosphorylation. Am J Pathol 147:601-608.
-
(1995)
Am J Pathol
, vol.147
, pp. 601-608
-
-
Sankar, S.1
Mahooti-Brooks, N.2
Hu, G.3
Madri, J.A.4
-
112
-
-
0033017955
-
Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers
-
Saoncella S, Echtermeyer F, Denhez F, Nowlen JK, Mosher DF, Robinson SD, Hynes RO, Goetinck PF. 1999. Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers. Proc Natl Acad Sci 96:2805-2810.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 2805-2810
-
-
Saoncella, S.1
Echtermeyer, F.2
Denhez, F.3
Nowlen, J.K.4
Mosher, D.F.5
Robinson, S.D.6
Hynes, R.O.7
Goetinck, P.F.8
-
113
-
-
0028986116
-
pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
-
Schaller MD, Parsons JT. 1995. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol 15:2635-2345.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2635-12345
-
-
Schaller, M.D.1
Parsons, J.T.2
-
114
-
-
0028350859
-
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60Src
-
Schaller MD, Hildebrand JD, Shannon JD, Fox JW, Vines RR, Parsons JT. 1994. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60Src. Mol Cell Biol 14:1680-1688.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1680-1688
-
-
Schaller, M.D.1
Hildebrand, J.D.2
Shannon, J.D.3
Fox, J.W.4
Vines, R.R.5
Parsons, J.T.6
-
115
-
-
0029150292
-
Focal adhesion kinase and paxillin bind to peptides mimicking beta integral cytoplasmic domains
-
Schaller MD, Otey CA, Hildebrand JD, Parsons JT. 1995. Focal adhesion kinase and paxillin bind to peptides mimicking beta integral cytoplasmic domains. J Cell Biol 130:1181-1187.
-
(1995)
J Cell Biol
, vol.130
, pp. 1181-1187
-
-
Schaller, M.D.1
Otey, C.A.2
Hildebrand, J.D.3
Parsons, J.T.4
-
116
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer DD, Hanks SK, Hunter T, Van der Geer P. 1994. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372:786-791.
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
Van Der Geer, P.4
-
117
-
-
0029832241
-
Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes
-
Schuebel KE, Bustelo XR, Nielsen DA, Song BJ, Barbacid M, Goldman D, Lee IJ. 1996. Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes. Oncogene 13:363-371.
-
(1996)
Oncogene
, vol.13
, pp. 363-371
-
-
Schuebel, K.E.1
Bustelo, X.R.2
Nielsen, D.A.3
Song, B.J.4
Barbacid, M.5
Goldman, D.6
Lee, I.J.7
-
119
-
-
0029827248
-
Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway
-
Schwartz MA, Toksoz D, Khosravi-Far R. 1996. Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway. EMBO J 15:6525-6530.
-
(1996)
EMBO J
, vol.15
, pp. 6525-6530
-
-
Schwartz, M.A.1
Toksoz, D.2
Khosravi-Far, R.3
-
121
-
-
0031456065
-
Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion
-
Shaw LM, Rabinovitz I, Wang HH, Toker A, Mercurio AM. 1997. Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion. Cell 91:949-960.
-
(1997)
Cell
, vol.91
, pp. 949-960
-
-
Shaw, L.M.1
Rabinovitz, I.2
Wang, H.H.3
Toker, A.4
Mercurio, A.M.5
-
122
-
-
0032513047
-
Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin
-
Shen Y, Schneider G, Cloutier JF, Veillette A, Schaller MD. 1998. Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin. J Biol Chem 273:6474-6481.
-
(1998)
J Biol Chem
, vol.273
, pp. 6474-6481
-
-
Shen, Y.1
Schneider, G.2
Cloutier, J.F.3
Veillette, A.4
Schaller, M.D.5
-
123
-
-
0032531732
-
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-/-cell migration
-
Sieg DJ, Ilic D, Jones KC, Damsky CH, Hunter T, Schlaepfer DD. 1998. Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-/-cell migration. EMBO J 17:5933-5947.
-
(1998)
EMBO J
, vol.17
, pp. 5933-5947
-
-
Sieg, D.J.1
Ilic, D.2
Jones, K.C.3
Damsky, C.H.4
Hunter, T.5
Schlaepfer, D.D.6
-
124
-
-
0028450653
-
Lamellipodia architecture: Actin filaments turnover and the lateral flow of actin filaments during motility
-
Small JV. 1994. Lamellipodia architecture: actin filaments turnover and the lateral flow of actin filaments during motility, Sem Cell Biol 5:157-163.
-
(1994)
Sem Cell Biol
, vol.5
, pp. 157-163
-
-
Small, J.V.1
-
125
-
-
0027299745
-
On the crawling of animal cells
-
Stossel TP. 1993. On the crawling of animal cells. Science 260:1086-1094.
-
(1993)
Science
, vol.260
, pp. 1086-1094
-
-
Stossel, T.P.1
-
126
-
-
0030006284
-
Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization
-
Symons M, Derry JM, Karlak B, Jiang S, Lemahieu V, Mccormick F, Francke U, Abo A. 1996. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell 84:723-734.
-
(1996)
Cell
, vol.84
, pp. 723-734
-
-
Symons, M.1
Derry, J.M.2
Karlak, B.3
Jiang, S.4
Lemahieu, V.5
McCormick, F.6
Francke, U.7
Abo, A.8
-
127
-
-
0032991640
-
Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho
-
Taylor JM, Macklem MM, Parsons JT. 1999. Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho. J Cell Sci 112:231-242.
-
(1999)
J Cell Sci
, vol.112
, pp. 231-242
-
-
Taylor, J.M.1
Macklem, M.M.2
Parsons, J.T.3
-
128
-
-
0028289562
-
Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: Identification of a vinculin and pp125Fak-binding region
-
Turner CE, Miller JT. 1994. Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding region. J Cell Sci 107:1583-1591.
-
(1994)
J Cell Sci
, vol.107
, pp. 1583-1591
-
-
Turner, C.E.1
Miller, J.T.2
-
129
-
-
0027373782
-
Activation of protein kinase C precedes alpha5/betal integrin-mediated cell spreading
-
Vuori K, Ruoslahti E. 1993. Activation of protein kinase C precedes alpha5/betal integrin-mediated cell spreading. J Biol Chem 268: 21459-21462.
-
(1993)
J Biol Chem
, vol.268
, pp. 21459-21462
-
-
Vuori, K.1
Ruoslahti, E.2
-
130
-
-
0029664531
-
Induction of p130Cas signaling complex formation upon integrin-mediated cell adhesion: A role for Src family kinases
-
Vuori K, Hirai H, Aizawa S, Ruoslahti E. 1996. Induction of p130Cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases. Mol Cell Biol 16:2606-2613.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2606-2613
-
-
Vuori, K.1
Hirai, H.2
Aizawa, S.3
Ruoslahti, E.4
-
131
-
-
0030584077
-
The adaptor protein She couples a class of integrins to the control of cell cycle progression
-
Wary KK, Mainiero F, Isakoff SJ, Marcantonio EE, Giancotti FG. 1996. The adaptor protein She couples a class of integrins to the control of cell cycle progression. Cell 87:733-743.
-
(1996)
Cell
, vol.87
, pp. 733-743
-
-
Wary, K.K.1
Mainiero, F.2
Isakoff, S.J.3
Marcantonio, E.E.4
Giancotti, F.G.5
-
132
-
-
0030911424
-
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin
-
Watanabe N, Madaule P, Reid T, Ishizaki T, Watanabe G, Kakizuka A, Saito Y, Nakao K, Jockusch BM, Narumiya S. 1997. p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J 16:3044-3056.
-
(1997)
EMBO J
, vol.16
, pp. 3044-3056
-
-
Watanabe, N.1
Madaule, P.2
Reid, T.3
Ishizaki, T.4
Watanabe, G.5
Kakizuka, A.6
Saito, Y.7
Nakao, K.8
Jockusch, B.M.9
Narumiya, S.10
-
133
-
-
0029918344
-
Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites
-
Weekes J, Barry ST, Critchley DR. 1996. Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites. Biochem J 314:827-832.
-
(1996)
Biochem J
, vol.314
, pp. 827-832
-
-
Weekes, J.1
Barry, S.T.2
Critchley, D.R.3
-
134
-
-
0026603414
-
Protein kinase C involvement in focal adhesion formation
-
Woods A, Couchman JR. 1992. Protein kinase C involvement in focal adhesion formation. J Cell Sci 101:277-290.
-
(1992)
J Cell Sci
, vol.101
, pp. 277-290
-
-
Woods, A.1
Couchman, J.R.2
-
135
-
-
0028213641
-
Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component
-
Woods A, Couchman JR. 1994. Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component. Mol Biol Cell 5:183-192.
-
(1994)
Mol Biol Cell
, vol.5
, pp. 183-192
-
-
Woods, A.1
Couchman, J.R.2
-
136
-
-
0032080892
-
Syndecans: Synergistic activators of cell adhesion
-
Woods A, Couchman JR. 1998. Syndecans: synergistic activators of cell adhesion. Trends Cell Biol 8:189-192.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 189-192
-
-
Woods, A.1
Couchman, J.R.2
-
137
-
-
0031048384
-
A three-dimensional collagen lattice induces protein kinase C-zeta activity: Role in alpha2 integrin and collagenase mRNA expression
-
Xu J, Clark RA. 1997. A three-dimensional collagen lattice induces protein kinase C-zeta activity: role in alpha2 integrin and collagenase mRNA expression. J Cell Biol 136:473-483.
-
(1997)
J Cell Biol
, vol.136
, pp. 473-483
-
-
Xu, J.1
Clark, R.A.2
-
138
-
-
0032565769
-
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
-
Yang N, Higuchi O, Ohashi K, Nagata K, Wada A, Kangawa K, Nishida E, Mizuno K. 1998. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393:809-812.
-
(1998)
Nature
, vol.393
, pp. 809-812
-
-
Yang, N.1
Higuchi, O.2
Ohashi, K.3
Nagata, K.4
Wada, A.5
Kangawa, K.6
Nishida, E.7
Mizuno, K.8
-
139
-
-
0029776031
-
Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav
-
Zheng L, Sjolander A, Eckerdal J, Andersson T. 1996. Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav. Proc Natl Acad Sci USA 93:8431-8436.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8431-8436
-
-
Zheng, L.1
Sjolander, A.2
Eckerdal, J.3
Andersson, T.4
|