Cell type-dependent proapoptotic role of Bcl2L12 revealed by a mutation concomitant with the disruption of the juxtaposed Irf3 gene

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 30, 2009, Pages 12448-12452

  Nakajima, Akira ^a   Nishimura, Keishiro ^a   Nakaima, Yukana ^a   Oh, Tomohiko ^a   Noguchi, Shigeru ^b,c   Taniguchi, Tadatsugu ^a   Tamura, Tomohiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY   (Japan)

^c MEIJI DAIRIES CORPORATION   (Japan)

Author keywords

Apoptosis; Golgi; Innate immunity; Mitochondria

Indexed keywords

BCL2L12 PROTEIN; CASPASE; CASPASE 2; INTERFERON; NUCLEIC ACID; PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL TYPE; DNA DAMAGE; FIBROBLAST; GENE ACTIVATION; GENE INDUCTION; GENE LOCUS; GENE MUTATION; IMMUNE RESPONSE; IRF3 GENE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; STIMULUS RESPONSE;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BLOTTING, WESTERN; CASPASES; CELLS, CULTURED; DNA DAMAGE; FIBROBLASTS; INTERFERON REGULATORY FACTOR-3; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MUSCLE PROTEINS; MUTATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYMUS GLAND; TRANSFECTION;

MUS;

EID: 68149159299     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0905702106     Document Type: Article

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