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Volumn 10, Issue 3, 2009, Pages 165-171

Long-term RNA interference and its application to hepatitis B virus

Author keywords

Antiviral agents; Effects; Gene silencing; Hepatitis B virus; Long term; RNA interference

Indexed keywords

APOLIPOPROTEIN A1; DOUBLE STRANDED RNA; LUCIFERASE; RNA POLYMERASE II; SHORT HAIRPIN RNA; TRANSACTIVATOR PROTEIN; VIRUS VECTOR;

EID: 68149158913     PISSN: 17512972     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-2980.2009.00381.x     Document Type: Review
Times cited : (4)

References (64)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998; 391: 806-11.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 2
    • 0036721314 scopus 로고    scopus 로고
    • Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
    • Coburn GA, Cullen BR. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J Virol. 2002; 76: 9225-31.
    • (2002) J Virol , vol.76 , pp. 9225-9231
    • Coburn, G.A.1    Cullen, B.R.2
  • 3
    • 0037418322 scopus 로고    scopus 로고
    • RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
    • Ge Q, McManus MT, Nguyen T et al. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci USA. 2003; 100: 2718-23.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2718-2723
    • Ge, Q.1    McManus, M.T.2    Nguyen, T.3
  • 4
    • 34248176226 scopus 로고    scopus 로고
    • Hepatitis B in China
    • Liu J, Fan D. Hepatitis B in China. Lancet. 2007; 369: 1582-3.
    • (2007) Lancet , vol.369 , pp. 1582-1583
    • Liu, J.1    Fan, D.2
  • 5
    • 33847701354 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • Lok AS, McMahon BJ. Chronic hepatitis B. Hepatology. 2007; 45: 507-39.
    • (2007) Hepatology , vol.45 , pp. 507-539
    • Lok, A.S.1    McMahon, B.J.2
  • 6
    • 13444309139 scopus 로고    scopus 로고
    • A randomized, controlled trial of combination therapy for chronic hepatitis B: Comparing pegylated interferon-alpha2b and lamivudine with lamivudine alone
    • Chan HL, Leung NW, Hui AY et al. A randomized, controlled trial of combination therapy for chronic hepatitis B: Comparing pegylated interferon-alpha2b and lamivudine with lamivudine alone. Ann Intern Med. 2005; 142: 240-50.
    • (2005) Ann Intern Med , vol.142 , pp. 240-250
    • Chan, H.L.1    Leung, N.W.2    Hui, A.Y.3
  • 7
    • 19944428132 scopus 로고    scopus 로고
    • PEGylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: A randomised trial
    • Janssen HL, van Zonneveld M, Senturk H et al. PEGylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: A randomised trial. Lancet. 2005; 365: 123-9.
    • (2005) Lancet , vol.365 , pp. 123-129
    • Janssen, H.L.1    van Zonneveld, M.2    Senturk, H.3
  • 8
    • 0034105307 scopus 로고    scopus 로고
    • Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: A randomised trial
    • Schalm SW, Heathcote J, Cianciara J et al. Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: A randomised trial. Gut. 2000; 46: 562-8.
    • (2000) Gut , vol.46 , pp. 562-568
    • Schalm, S.W.1    Heathcote, J.2    Cianciara, J.3
  • 9
    • 0141755412 scopus 로고    scopus 로고
    • Inhibition of HBV replication by siRNA in a stable HBV-producing cell line
    • Konishi M, Wu CH, Wu GY. Inhibition of HBV replication by siRNA in a stable HBV-producing cell line. Hepatology. 2003; 38: 842-50.
    • (2003) Hepatology , vol.38 , pp. 842-850
    • Konishi, M.1    Wu, C.H.2    Wu, G.Y.3
  • 10
    • 0038023197 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus in mice by RNA interference
    • McCaffrey AP, Nakai H, Pandey K et al. Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol. 2003; 21: 639-44.
    • (2003) Nat Biotechnol , vol.21 , pp. 639-644
    • McCaffrey, A.P.1    Nakai, H.2    Pandey, K.3
  • 11
    • 0041923781 scopus 로고    scopus 로고
    • Selective inhibition of hepatitis B virus replication by RNA interference
    • Ying C, De Clercq E, Neyts J. Selective inhibition of hepatitis B virus replication by RNA interference. Biochem Biophys Res Commun. 2003; 309: 482-4.
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 482-484
    • Ying, C.1    De Clercq, E.2    Neyts, J.3
  • 12
    • 1242316928 scopus 로고    scopus 로고
    • Biodistribution of phosphodiester and phosphorothioate siRNA
    • Braasch DA, Paroo Z, Constantinescu A et al. Biodistribution of phosphodiester and phosphorothioate siRNA. Bioorg Med Chem Lett. 2004; 14: 1139-43.
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 1139-1143
    • Braasch, D.A.1    Paroo, Z.2    Constantinescu, A.3
  • 13
    • 2442669339 scopus 로고    scopus 로고
    • RNA interference
    • Downward J. RNA interference. BMJ. 2004; 328: 1245-8.
    • (2004) BMJ , vol.328 , pp. 1245-1248
    • Downward, J.1
  • 14
    • 6044248871 scopus 로고    scopus 로고
    • Therapeutic potential of RNA interference
    • Stevenson M. Therapeutic potential of RNA interference. N Engl J Med. 2004; 351: 1772-7.
    • (2004) N Engl J Med , vol.351 , pp. 1772-1777
    • Stevenson, M.1
  • 15
    • 21344457432 scopus 로고    scopus 로고
    • RNA interference: From gene silencing to gene-specific therapeutics
    • Leung RK, Whittaker PA. RNA interference: From gene silencing to gene-specific therapeutics. Pharmacol Ther. 2005; 107: 222-39.
    • (2005) Pharmacol Ther , vol.107 , pp. 222-239
    • Leung, R.K.1    Whittaker, P.A.2
  • 16
    • 9144247189 scopus 로고    scopus 로고
    • Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
    • Soutschek J, Akinc A, Bramlage B et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature. 2004; 432: 173-8.
    • (2004) Nature , vol.432 , pp. 173-178
    • Soutschek, J.1    Akinc, A.2    Bramlage, B.3
  • 17
    • 20044396377 scopus 로고    scopus 로고
    • Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication
    • Morrissey DV, Blanchard K, Shaw L et al. Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication. Hepatology. 2005; 41: 1349-56.
    • (2005) Hepatology , vol.41 , pp. 1349-1356
    • Morrissey, D.V.1    Blanchard, K.2    Shaw, L.3
  • 18
    • 2942530436 scopus 로고    scopus 로고
    • Inhibition of influenza virus production in virus-infected mice by RNA interference
    • Ge Q, Filip L, Bai A, Nguyen T, Eisen HN, Chen J. Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc Natl Acad Sci U S A. 2004; 101: 8676-81.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8676-8681
    • Ge, Q.1    Filip, L.2    Bai, A.3    Nguyen, T.4    Eisen, H.N.5    Chen, J.6
  • 20
    • 1642307857 scopus 로고    scopus 로고
    • Transposon-based RNAi delivery system for generating knockdown cell lines
    • Heggestad AD, Notterpek L, Fletcher BS. Transposon-based RNAi delivery system for generating knockdown cell lines. Biochem Biophys Res Commun. 2004; 316: 643-50.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 643-650
    • Heggestad, A.D.1    Notterpek, L.2    Fletcher, B.S.3
  • 21
    • 0347418186 scopus 로고    scopus 로고
    • Tests of cytoplasmic RNA interference (RNAi) and construction of a tetracycline-inducible T7 promoter system in Trypanosoma cruzi
    • DaRocha WD, Otsu K, Teixeira SM, Donelson JE. Tests of cytoplasmic RNA interference (RNAi) and construction of a tetracycline-inducible T7 promoter system in Trypanosoma cruzi. Mol Biochem Parasitol. 2004; 133: 175-86.
    • (2004) Mol Biochem Parasitol , vol.133 , pp. 175-186
    • DaRocha, W.D.1    Otsu, K.2    Teixeira, S.M.3    Donelson, J.E.4
  • 22
    • 4344608398 scopus 로고    scopus 로고
    • An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of Langerhans
    • Bain JR, Schisler JC, Takeuchi K, Newgard CB, Becker TC. An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of Langerhans. Diabetes. 2004; 53: 2190-4.
    • (2004) Diabetes , vol.53 , pp. 2190-2194
    • Bain, J.R.1    Schisler, J.C.2    Takeuchi, K.3    Newgard, C.B.4    Becker, T.C.5
  • 23
    • 1642443401 scopus 로고    scopus 로고
    • Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors
    • Boden D, Pusch O, Lee F, Tucker L, Ramratnam B. Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors. Mol Ther. 2004; 9: 396-402.
    • (2004) Mol Ther , vol.9 , pp. 396-402
    • Boden, D.1    Pusch, O.2    Lee, F.3    Tucker, L.4    Ramratnam, B.5
  • 24
    • 9944230421 scopus 로고    scopus 로고
    • Long-term in vivo and in vitro AAV-2-mediated RNA interference in rat retinal ganglion cells and cultured primary neurons
    • Michel U, Malik I, Ebert S, Bahr M, Kugler S. Long-term in vivo and in vitro AAV-2-mediated RNA interference in rat retinal ganglion cells and cultured primary neurons. Biochem Biophys Res Commun. 2005; 326: 307-12.
    • (2005) Biochem Biophys Res Commun , vol.326 , pp. 307-312
    • Michel, U.1    Malik, I.2    Ebert, S.3    Bahr, M.4    Kugler, S.5
  • 25
    • 3843087480 scopus 로고    scopus 로고
    • Retrovirally mediated RNA interference targeting the M2 subunit of ribonucleotide reductase: A novel therapeutic strategy in pancreatic cancer
    • Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. Retrovirally mediated RNA interference targeting the M2 subunit of ribonucleotide reductase: A novel therapeutic strategy in pancreatic cancer. Surgery. 2004; 136: 261-9.
    • (2004) Surgery , vol.136 , pp. 261-269
    • Duxbury, M.S.1    Ito, H.2    Benoit, E.3    Zinner, M.J.4    Ashley, S.W.5    Whang, E.E.6
  • 26
    • 1842737717 scopus 로고    scopus 로고
    • Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference
    • Schuck S, Manninen A, Honsho M, Fullekrug J, Simons K. Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference. Proc Natl Acad Sci USA. 2004; 101: 4912-7.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4912-4917
    • Schuck, S.1    Manninen, A.2    Honsho, M.3    Fullekrug, J.4    Simons, K.5
  • 28
    • 0042267194 scopus 로고    scopus 로고
    • Efficient lentiviral vectors for short hairpin RNA delivery into human cells
    • An DS, Xie Y, Mao SH, Morizono K, Kung SK, Chen IS. Efficient lentiviral vectors for short hairpin RNA delivery into human cells. Hum Gene Ther. 2003; 14: 1207-12.
    • (2003) Hum Gene Ther , vol.14 , pp. 1207-1212
    • An, D.S.1    Xie, Y.2    Mao, S.H.3    Morizono, K.4    Kung, S.K.5    Chen, I.S.6
  • 29
    • 17644383664 scopus 로고    scopus 로고
    • Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS
    • Raoul C, Abbas-Terki T, Bensadoun JC et al. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS. Nat Med. 2005; 11: 423-8.
    • (2005) Nat Med , vol.11 , pp. 423-428
    • Raoul, C.1    Abbas-Terki, T.2    Bensadoun, J.C.3
  • 30
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson DA, Dillon CP, Kwiatkowski AV et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet. 2003; 33: 401-6.
    • (2003) Nat Genet , vol.33 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3
  • 31
    • 1942437667 scopus 로고    scopus 로고
    • Potato virus X-induced gene silencing in leaves and tubers of potato
    • Faivre-Rampant O, Gilroy EM, Hrubikova K et al. Potato virus X-induced gene silencing in leaves and tubers of potato. Plant Physiol. 2004; 134: 1308-16.
    • (2004) Plant Physiol , vol.134 , pp. 1308-1316
    • Faivre-Rampant, O.1    Gilroy, E.M.2    Hrubikova, K.3
  • 33
    • 0034623009 scopus 로고    scopus 로고
    • Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates
    • Izsvak Z, Ivics Z, Plasterk RH. Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates. J Mol Biol. 2000; 302: 93-102.
    • (2000) J Mol Biol , vol.302 , pp. 93-102
    • Izsvak, Z.1    Ivics, Z.2    Plasterk, R.H.3
  • 34
    • 23744479962 scopus 로고    scopus 로고
    • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
    • Ding S, Wu X, Li G, Han M, Zhuang Y, Xu T. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell. 2005; 122: 473-83.
    • (2005) Cell , vol.122 , pp. 473-483
    • Ding, S.1    Wu, X.2    Li, G.3    Han, M.4    Zhuang, Y.5    Xu, T.6
  • 35
    • 20044378849 scopus 로고    scopus 로고
    • Heritable transposon silencing initiated by a naturally occurring transposon inverted duplication
    • Slotkin RK, Freeling M, Lisch D. Heritable transposon silencing initiated by a naturally occurring transposon inverted duplication. Nat Genet. 2005; 37: 641-4.
    • (2005) Nat Genet , vol.37 , pp. 641-644
    • Slotkin, R.K.1    Freeling, M.2    Lisch, D.3
  • 36
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell. 1993; 72: 971-83.
    • (1993) Cell , vol.72 , pp. 971-983
  • 37
    • 14644445202 scopus 로고    scopus 로고
    • Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference
    • Chen ZJ, Kren BT, Wong PY, Low WC, Steer CJ. Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference. Biochem Biophys Res Commun. 2005; 329: 646-52.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 646-652
    • Chen, Z.J.1    Kren, B.T.2    Wong, P.Y.3    Low, W.C.4    Steer, C.J.5
  • 38
    • 0034103009 scopus 로고    scopus 로고
    • Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
    • Yant SR, Meuse L, Chiu W, Ivics Z, Izsvak Z, Kay MA. Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. Nat Genet. 2000; 25: 35-41.
    • (2000) Nat Genet , vol.25 , pp. 35-41
    • Yant, S.R.1    Meuse, L.2    Chiu, W.3    Ivics, Z.4    Izsvak, Z.5    Kay, M.A.6
  • 39
    • 0038303229 scopus 로고    scopus 로고
    • Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin
    • Wang J, Tekle E, Oubrahim H, Mieyal JJ, Stadtman ER, Chock PB. Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin. Proc Natl Acad Sci USA. 2003; 100: 5103-6.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5103-5106
    • Wang, J.1    Tekle, E.2    Oubrahim, H.3    Mieyal, J.J.4    Stadtman, E.R.5    Chock, P.B.6
  • 40
    • 11144327213 scopus 로고    scopus 로고
    • A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei
    • Alibu VP, Storm L, Haile S, Clayton C, Horn D. A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei. Mol Biochem Parasitol. 2005; 139: 75-82.
    • (2005) Mol Biochem Parasitol , vol.139 , pp. 75-82
    • Alibu, V.P.1    Storm, L.2    Haile, S.3    Clayton, C.4    Horn, D.5
  • 41
    • 18344383777 scopus 로고    scopus 로고
    • Conditional inhibition of cancer cell proliferation by tetracycline-responsive, H1 promoter-driven silencing of PLK1
    • Matthess Y, Kappel S, Spankuch B, Zimmer B, Kaufmann M, Strebhardt K. Conditional inhibition of cancer cell proliferation by tetracycline-responsive, H1 promoter-driven silencing of PLK1. Oncogene. 2005; 24: 2973-80.
    • (2005) Oncogene , vol.24 , pp. 2973-2980
    • Matthess, Y.1    Kappel, S.2    Spankuch, B.3    Zimmer, B.4    Kaufmann, M.5    Strebhardt, K.6
  • 43
    • 18144453718 scopus 로고    scopus 로고
    • Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system
    • Coumoul X, Li W, Wang RH, Deng C. Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system. Nucleic Acids Res. 2004; 32: E85.
    • (2004) Nucleic Acids Res , vol.32
    • Coumoul, X.1    Li, W.2    Wang, R.H.3    Deng, C.4
  • 44
    • 68149111291 scopus 로고    scopus 로고
    • Geneva: World Health Organization, October 2000. Cited 25 Nov. 2008. Available from URL
    • Hepatitis B. Fact sheet WHO No. 204. Geneva: World Health Organization, October 2000. Cited 25 Nov. 2008. Available from URL: http://www.who.int/ mediacentre/factsheets/fs204/en/index.html.
    • Fact Sheet WHO No. 204
    • Hepatitis, B.1
  • 45
    • 20444363583 scopus 로고    scopus 로고
    • Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update
    • Liaw YF, Leung N, Guan R et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update. Liver Int. 2005; 25: 472-89.
    • (2005) Liver Int , vol.25 , pp. 472-489
    • Liaw, Y.F.1    Leung, N.2    Guan, R.3
  • 46
    • 58149291663 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces lipogenic transcription factor SREBP1 and fatty acid synthase through the activation of nuclear receptor LXRalpha
    • Kim K, Kim KH, Kim HH, Cheong J. Hepatitis B virus X protein induces lipogenic transcription factor SREBP1 and fatty acid synthase through the activation of nuclear receptor LXRalpha. Biochem J. 2008; 416: 219-30.
    • (2008) Biochem J , vol.416 , pp. 219-230
    • Kim, K.1    Kim, K.H.2    Kim, H.H.3    Cheong, J.4
  • 47
    • 38349130478 scopus 로고    scopus 로고
    • Effects of HBV X gene and arsenic trioxide on the expression of p53 in cultured HepG2 cells
    • Lei JH, He XE, Yang X et al. Effects of HBV X gene and arsenic trioxide on the expression of p53 in cultured HepG2 cells. Chin Med J (Engl). 2007; 120: 2181-4.
    • (2007) Chin Med J (Engl) , vol.120 , pp. 2181-2184
    • Lei, J.H.1    He, X.E.2    Yang, X.3
  • 48
    • 46249123203 scopus 로고    scopus 로고
    • Long-term suppression of hepatitis B virus replication by short hairpin RNA expression using the scaffold/matrix attachment region-based replicating vector system pEPI-1
    • Jenke AC, Wilhelm AD, Orth V, Lipps HJ, Protzer U, Wirth S. Long-term suppression of hepatitis B virus replication by short hairpin RNA expression using the scaffold/matrix attachment region-based replicating vector system pEPI-1. Antimicrob Agents Chemother. 2008; 52: 2355-9.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2355-2359
    • Jenke, A.C.1    Wilhelm, A.D.2    Orth, V.3    Lipps, H.J.4    Protzer, U.5    Wirth, S.6
  • 49
    • 50549092566 scopus 로고    scopus 로고
    • Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic
    • Giering JC, Grimm D, Storm TA, Kay MA. Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic. Mol Ther. 2008; 16: 1630-6.
    • (2008) Mol Ther , vol.16 , pp. 1630-1636
    • Giering, J.C.1    Grimm, D.2    Storm, T.A.3    Kay, M.A.4
  • 50
    • 34547403273 scopus 로고    scopus 로고
    • Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery
    • Wen WH, Liu JY, Qin WJ et al. Targeted inhibition of HBV gene expression by single-chain antibody mediated small interfering RNA delivery. Hepatology. 2007; 46: 84-94.
    • (2007) Hepatology , vol.46 , pp. 84-94
    • Wen, W.H.1    Liu, J.Y.2    Qin, W.J.3
  • 51
    • 34249279852 scopus 로고    scopus 로고
    • Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I
    • Kim SI, Shin D, Choi TH et al. Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I. Mol Ther. 2007; 15: 1145-52.
    • (2007) Mol Ther , vol.15 , pp. 1145-1152
    • Kim, S.I.1    Shin, D.2    Choi, T.H.3
  • 52
    • 49349104504 scopus 로고    scopus 로고
    • Exploring gene-deleted adenoviral vectors for delivery of short hairpin RNAs and reduction of hepatitis B virus infection in mice
    • Rauschhuber C, Xu H, Salazar FH, Marion PL, Ehrhardt A. Exploring gene-deleted adenoviral vectors for delivery of short hairpin RNAs and reduction of hepatitis B virus infection in mice. J Gene Med. 2008; 10: 878-89.
    • (2008) J Gene Med , vol.10 , pp. 878-889
    • Rauschhuber, C.1    Xu, H.2    Salazar, F.H.3    Marion, P.L.4    Ehrhardt, A.5
  • 53
    • 34848852743 scopus 로고    scopus 로고
    • The short hairpin RNA driven by polymerase II suppresses both wild-type and lamivudine-resistant hepatitis B virus strains
    • Ren GL, Fang Y, Ma HH et al. The short hairpin RNA driven by polymerase II suppresses both wild-type and lamivudine-resistant hepatitis B virus strains. Antivir Ther. 2007; 12: 865-76.
    • (2007) Antivir Ther , vol.12 , pp. 865-876
    • Ren, G.L.1    Fang, Y.2    Ma, H.H.3
  • 54
    • 34249860595 scopus 로고    scopus 로고
    • Combination of small interfering RNA and lamivudine on inhibition of human B virus replication in HepG2.2.15 cells
    • Li GQ, Xu WZ, Wang JX, Deng WW, Li D, Gu HX. Combination of small interfering RNA and lamivudine on inhibition of human B virus replication in HepG2.2.15 cells. World J Gastroenterol. 2007; 13: 2324-7.
    • (2007) World J Gastroenterol , vol.13 , pp. 2324-2327
    • Li, G.Q.1    Xu, W.Z.2    Wang, J.X.3    Deng, W.W.4    Li, D.5    Gu, H.X.6
  • 55
    • 38049177362 scopus 로고    scopus 로고
    • Site-directed, virus-free, and inducible RNAi in embryonic stem cells
    • Wang J, Theunissen TW, Orkin SH. Site-directed, virus-free, and inducible RNAi in embryonic stem cells. Proc Natl Acad Sci USA. 2007; 104: 20850-5.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20850-20855
    • Wang, J.1    Theunissen, T.W.2    Orkin, S.H.3
  • 56
    • 38349135364 scopus 로고    scopus 로고
    • Gene knockdown by ecdysone-based inducible RNAi in stable mammalian cell lines
    • Rangasamy D, Tremethick DJ, Greaves IK. Gene knockdown by ecdysone-based inducible RNAi in stable mammalian cell lines. Nat Protoc. 2008; 3: 79-88.
    • (2008) Nat Protoc , vol.3 , pp. 79-88
    • Rangasamy, D.1    Tremethick, D.J.2    Greaves, I.K.3
  • 57
    • 0037685280 scopus 로고    scopus 로고
    • Expression profiling reveals off-target gene regulation by RNAi
    • Jackson AL, Bartz SR, Schelter J et al. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol. 2003; 21: 635-7.
    • (2003) Nat Biotechnol , vol.21 , pp. 635-637
    • Jackson, A.L.1    Bartz, S.R.2    Schelter, J.3
  • 58
    • 0142173075 scopus 로고    scopus 로고
    • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
    • Saxena S, Jonsson ZO, Dutta A. Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells. J Biol Chem. 2003; 278: 44312-9.
    • (2003) J Biol Chem , vol.278 , pp. 44312-44319
    • Saxena, S.1    Jonsson, Z.O.2    Dutta, A.3
  • 59
    • 17844387370 scopus 로고    scopus 로고
    • A computational study of off-target effects of RNA interference
    • Qiu S, Adema CM, Lane T. A computational study of off-target effects of RNA interference. Nucleic Acids Res. 2005; 33: 1834-47.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1834-1847
    • Qiu, S.1    Adema, C.M.2    Lane, T.3
  • 60
    • 0037448352 scopus 로고    scopus 로고
    • A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
    • Hacein-Bey-Abina S, von Kalle C, Schmidt M et al. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N Engl J Med. 2003; 348: 255-6.
    • (2003) N Engl J Med , vol.348 , pp. 255-256
    • Hacein-Bey-Abina, S.1    von Kalle, C.2    Schmidt, M.3
  • 61
    • 0037449534 scopus 로고    scopus 로고
    • Gene therapy. Second child in French trial is found to have leukemia
    • Marshall E. Gene therapy. Second child in French trial is found to have leukemia. Science. 2003; 299: 320.
    • (2003) Science , vol.299 , pp. 320
    • Marshall, E.1
  • 62
    • 1242319384 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition
    • Das AT, Brummelkamp TR, Westerhout EM et al. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J Virol. 2004; 78: 2601-5.
    • (2004) J Virol , vol.78 , pp. 2601-2605
    • Das, A.T.1    Brummelkamp, T.R.2    Westerhout, E.M.3
  • 63
    • 15744372307 scopus 로고    scopus 로고
    • RNA interference-mediated control of hepatitis B virus and emergence of resistant mutant
    • Wu HL, Huang LR, Huang CC et al. RNA interference-mediated control of hepatitis B virus and emergence of resistant mutant. Gastroenterology. 2005; 128: 708-16.
    • (2005) Gastroenterology , vol.128 , pp. 708-716
    • Wu, H.L.1    Huang, L.R.2    Huang, C.C.3
  • 64
    • 33745299723 scopus 로고    scopus 로고
    • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
    • Grimm D, Streetz KL, Jopling CL et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature. 2006; 441: 537-41.
    • (2006) Nature , vol.441 , pp. 537-541
    • Grimm, D.1    Streetz, K.L.2    Jopling, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.