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Volumn 9, Issue 5, 2009, Pages 543-549

Can the status of the breast and ovarian cancer susceptibility gene 1 product (BRCA1) predict response to taxane-based cancer therapy?

Author keywords

Biomarker; BRCA1; Cancer; Chemotherapy; Microtubule; Taxane; Taxol; Tubulin

Indexed keywords

AURORA KINASE INHIBITOR; BRCA1 PROTEIN; CARBOPLATIN; CHECKPOINT KINASE 1; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FLUOROURACIL; GEMCITABINE; NAVELBINE; PACLITAXEL;

EID: 67651112151     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152009788451798     Document Type: Short Survey
Times cited : (16)

References (75)
  • 1
    • 0015211527 scopus 로고
    • Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
    • Wani, M.C.; Taylor, H.L.; Wall, M.E.; Coggon, P.; McPhail, A.T. Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Chem. Soc. 1971, 93(9), 2325-2327.
    • (1971) J. Am. Chem. Soc , vol.93 , Issue.9 , pp. 2325-2327
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3    Coggon, P.4    McPhail, A.T.5
  • 2
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by taxol
    • Schiff, P.B.; Fant, J.; Horwitz, S.B. Promotion of microtubule assembly in vitro by taxol. Nature 1979, 277(5698), 665-667.
    • (1979) Nature , vol.277 , Issue.5698 , pp. 665-667
    • Schiff, P.B.1    Fant, J.2    Horwitz, S.B.3
  • 3
    • 0000297058 scopus 로고
    • Taxol stabilizes microtubules in mouse fibroblast cells
    • Schiff, P.B.; Horwitz, S.B. Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl. Acad. Sci. USA 1980, 77(3), 1561-1565.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , Issue.3 , pp. 1561-1565
    • Schiff, P.B.1    Horwitz, S.B.2
  • 4
    • 0030709242 scopus 로고    scopus 로고
    • Multiple forms of tubulin: Different gene products and covalent modifications
    • Luduena, R.F. Multiple forms of tubulin: different gene products and covalent modifications. Int. Rev. Cytol. 1998, 178, 207-275.
    • (1998) Int. Rev. Cytol , vol.178 , pp. 207-275
    • Luduena, R.F.1
  • 5
  • 6
    • 0028861177 scopus 로고
    • Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin
    • Rao, S.; Orr, G.A.; Chaudhary, A.G.; Kingston, D.G.; Horwitz, S.B. Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin. J. Biol. Chem. 1995, 270(35), 20235-20238.
    • (1995) J. Biol. Chem , vol.270 , Issue.35 , pp. 20235-20238
    • Rao, S.1    Orr, G.A.2    Chaudhary, A.G.3    Kingston, D.G.4    Horwitz, S.B.5
  • 7
    • 0033621479 scopus 로고    scopus 로고
    • Characterization of the Taxol binding site on the microtubule. Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol
    • Rao, S.; He, L.; Chakravarty, S.; Ojima, I.; Orr, G.A.; Horwitz, S.B. Characterization of the Taxol binding site on the microtubule. Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol. J. Biol. Chem. 1999, 274(53), 37990-37994.
    • (1999) J. Biol. Chem , vol.274 , Issue.53 , pp. 37990-37994
    • Rao, S.1    He, L.2    Chakravarty, S.3    Ojima, I.4    Orr, G.A.5    Horwitz, S.B.6
  • 8
    • 0032495513 scopus 로고    scopus 로고
    • Structure of the alpha beta tubulin dimer by electron crystallography
    • Nogales, E.; Wolf, S.G.; Downing, K.H. Structure of the alpha beta tubulin dimer by electron crystallography. Nature 1998, 391(6663), 199-203.
    • (1998) Nature , vol.391 , Issue.6663 , pp. 199-203
    • Nogales, E.1    Wolf, S.G.2    Downing, K.H.3
  • 9
    • 0030758777 scopus 로고    scopus 로고
    • Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization
    • Giannakakou, P.; Sackett, D.L.; Kang, Y.K.; Zhan, Z.; Buters, J.T.; Fojo, T.; Poruchynsky, M.S. Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization. J. Biol. Chem. 1997, 272(27), 17118-17125.
    • (1997) J. Biol. Chem , vol.272 , Issue.27 , pp. 17118-17125
    • Giannakakou, P.1    Sackett, D.L.2    Kang, Y.K.3    Zhan, Z.4    Buters, J.T.5    Fojo, T.6    Poruchynsky, M.S.7
  • 10
    • 0033588254 scopus 로고    scopus 로고
    • A beta-tubulin leucine cluster involved in microtubule assembly and paclitaxel resistance
    • Gonzalez-Garay, M.L.; Chang, L.; Blade, K.; Menick, D.R.; Cabral, F.A beta-tubulin leucine cluster involved in microtubule assembly and paclitaxel resistance. J. Biol. Chem. 1999, 274(34), 23875-23882.
    • (1999) J. Biol. Chem , vol.274 , Issue.34 , pp. 23875-23882
    • Gonzalez-Garay, M.L.1    Chang, L.2    Blade, K.3    Menick, D.R.4    Cabral, F.5
  • 12
    • 0037445132 scopus 로고    scopus 로고
    • Henderson, I.C.; Berry, D.A.; Demetri, G.D.; Cirrincione, C.T.; Goldstein, L.J.; Martino, S.; Ingle, J.N.; Cooper, M.R.; Hayes, D.F.; Tkaczuk, K.H.; Fleming, G.; Holland, J.F.; Duggan, D.B.; Carpenter, J.T.; Frei, E., III; Schilsky, R.L.; Wood, W.C.; Muss, H.B.; Norton, L. Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J. Clin. Oncol. 2003, 21(6), 976-983.
    • Henderson, I.C.; Berry, D.A.; Demetri, G.D.; Cirrincione, C.T.; Goldstein, L.J.; Martino, S.; Ingle, J.N.; Cooper, M.R.; Hayes, D.F.; Tkaczuk, K.H.; Fleming, G.; Holland, J.F.; Duggan, D.B.; Carpenter, J.T.; Frei, E., III; Schilsky, R.L.; Wood, W.C.; Muss, H.B.; Norton, L. Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J. Clin. Oncol. 2003, 21(6), 976-983.
  • 13
    • 0037687355 scopus 로고    scopus 로고
    • Citron, M.L.; Berry, D.A.; Cirrincione, C.; Hudis, C.; Winer, E.P.; Gradishar, W.J.; Davidson, N.E.; Martino, S.; Livingston, R.; Ingle, J.N.; Perez, E.A.; Carpenter, J.; Hurd, D.; Holland, J.F.; Smith, B.L.; Sartor, C.I.; Leung, E.H.; Abrams, J.; Schilsky, R.L.; Muss, H.B.; Norton, L. Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J. Clin. Oncol. 2003, 21(8), 1431-1439.
    • Citron, M.L.; Berry, D.A.; Cirrincione, C.; Hudis, C.; Winer, E.P.; Gradishar, W.J.; Davidson, N.E.; Martino, S.; Livingston, R.; Ingle, J.N.; Perez, E.A.; Carpenter, J.; Hurd, D.; Holland, J.F.; Smith, B.L.; Sartor, C.I.; Leung, E.H.; Abrams, J.; Schilsky, R.L.; Muss, H.B.; Norton, L. Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J. Clin. Oncol. 2003, 21(8), 1431-1439.
  • 15
    • 21144435932 scopus 로고    scopus 로고
    • Martin, M.; Pienkowski, T.; Mackey, J.; Pawlicki, M.; Guastalla, J.P.; Weaver, C.; Tomiak, E.; Al-Tweigeri, T.; Chap, L.; Juhos, E.; Guevin, R.; Howell, A.; Fornander, T.; Hainsworth, J.; Coleman, R.; Vinholes, J.; Modiano, M.; Pinter, T.; Tang, S.C.; Colwell, B.; Prady, C.; Provencher, L.; Walde, D.; Rodriguez-Lescure, A.; Hugh, J.; Loret, C.; Rupin, M.; Blitz, S.; Jacobs, P.; Murawsky, M.; Riva, A.; Vogel, C. Adjuvant docetaxel for node-positive breast cancer. N. Engl. J. Med. 2005, 352(22), 2302-2313.
    • Martin, M.; Pienkowski, T.; Mackey, J.; Pawlicki, M.; Guastalla, J.P.; Weaver, C.; Tomiak, E.; Al-Tweigeri, T.; Chap, L.; Juhos, E.; Guevin, R.; Howell, A.; Fornander, T.; Hainsworth, J.; Coleman, R.; Vinholes, J.; Modiano, M.; Pinter, T.; Tang, S.C.; Colwell, B.; Prady, C.; Provencher, L.; Walde, D.; Rodriguez-Lescure, A.; Hugh, J.; Loret, C.; Rupin, M.; Blitz, S.; Jacobs, P.; Murawsky, M.; Riva, A.; Vogel, C. Adjuvant docetaxel for node-positive breast cancer. N. Engl. J. Med. 2005, 352(22), 2302-2313.
  • 16
    • 0642347622 scopus 로고    scopus 로고
    • The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: Preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27
    • Bear, H.D.; Anderson, S.; Brown, A.; Smith, R.; Mamounas, E.P.; Fisher, B.; Margolese, R.; Theoret, H.; Soran, A.; Wickerham, D.L.; Wolmark, N. The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27. J. Clin. Oncol. 2003, 21(22), 4165-4174.
    • (2003) J. Clin. Oncol , vol.21 , Issue.22 , pp. 4165-4174
    • Bear, H.D.1    Anderson, S.2    Brown, A.3    Smith, R.4    Mamounas, E.P.5    Fisher, B.6    Margolese, R.7    Theoret, H.8    Soran, A.9    Wickerham, D.L.10    Wolmark, N.11
  • 20
    • 56449124059 scopus 로고    scopus 로고
    • Vinorelbine plus gemcitabine followed by docetaxel versus carboplatin plus paclitaxel in patients with advanced non-small-cell lung cancer: A randomised, open-label, phase III study
    • Kubota, K.; Kawahara, M.; Ogawara, M.; Nishiwaki, Y.; Komuta, K.; Minato, K.; Fujita, Y.; Teramukai, S.; Fukushima, M.; Furuse, K. Vinorelbine plus gemcitabine followed by docetaxel versus carboplatin plus paclitaxel in patients with advanced non-small-cell lung cancer: a randomised, open-label, phase III study. Lancet Oncol. 2008, 9(12), 1135-1142.
    • (2008) Lancet Oncol , vol.9 , Issue.12 , pp. 1135-1142
    • Kubota, K.1    Kawahara, M.2    Ogawara, M.3    Nishiwaki, Y.4    Komuta, K.5    Minato, K.6    Fujita, Y.7    Teramukai, S.8    Fukushima, M.9    Furuse, K.10
  • 21
    • 56449114914 scopus 로고    scopus 로고
    • Lung cancer: Moving forward with tailored strategies
    • Barlesi, F. Lung cancer: moving forward with tailored strategies. Lancet Oncol. 2008, 9(12), 1116-1117.
    • (2008) Lancet Oncol , vol.9 , Issue.12 , pp. 1116-1117
    • Barlesi, F.1
  • 22
    • 42249094731 scopus 로고    scopus 로고
    • Pharmaceutical management of ovarian cancer: Current status
    • Markman, M. Pharmaceutical management of ovarian cancer: current status. Drugs 2008, 68(6), 771-789.
    • (2008) Drugs , vol.68 , Issue.6 , pp. 771-789
    • Markman, M.1
  • 23
    • 0034600305 scopus 로고    scopus 로고
    • Piccart, M.J.; Bertelsen, K.; James, K.; Cassidy, J.; Mangioni, C.; Simonsen, E.; Stuart, G.; Kaye, S.; Vergote, I.; Blom, R.; Grimshaw, R.; Atkinson, R.J.; Swenerton, K.D.; Trope, C.; Nardi, M.; Kaern, J.; Tumolo, S.; Timmers, P.; Roy, J.A.; Lhoas, F.; Lindvall, B.; Bacon, M.; Birt, A.; Andersen, J.E.; Zee, B.; Paul, J.; Baron, B.; Pecorelli, S. Randomized intergroup trial of cisplatinpaclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: three-year results. J. Natl. Cancer Inst. 2000, 92(9), 699-708.
    • Piccart, M.J.; Bertelsen, K.; James, K.; Cassidy, J.; Mangioni, C.; Simonsen, E.; Stuart, G.; Kaye, S.; Vergote, I.; Blom, R.; Grimshaw, R.; Atkinson, R.J.; Swenerton, K.D.; Trope, C.; Nardi, M.; Kaern, J.; Tumolo, S.; Timmers, P.; Roy, J.A.; Lhoas, F.; Lindvall, B.; Bacon, M.; Birt, A.; Andersen, J.E.; Zee, B.; Paul, J.; Baron, B.; Pecorelli, S. Randomized intergroup trial of cisplatinpaclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: three-year results. J. Natl. Cancer Inst. 2000, 92(9), 699-708.
  • 24
    • 9744223515 scopus 로고    scopus 로고
    • Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma
    • Vasey, P.A.; Jayson, G.C.; Gordon, A.; Gabra, H.; Coleman, R.; Atkinson, R.; Parkin, D.; Paul, J.; Hay, A.; Kaye, S.B. Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma. J. Natl. Cancer Inst. 2004, 96(22), 1682-1691.
    • (2004) J. Natl. Cancer Inst , vol.96 , Issue.22 , pp. 1682-1691
    • Vasey, P.A.1    Jayson, G.C.2    Gordon, A.3    Gabra, H.4    Coleman, R.5    Atkinson, R.6    Parkin, D.7    Paul, J.8    Hay, A.9    Kaye, S.B.10
  • 25
    • 36049015023 scopus 로고    scopus 로고
    • A systematic review of platinum and taxane resistance from bench to clinic: An inverse relationship
    • Stordal, B.; Pavlakis, N.; Davey, R.A systematic review of platinum and taxane resistance from bench to clinic: an inverse relationship. Cancer Treat. Rev. 2007, 33(8), 688-703.
    • (2007) Cancer Treat. Rev , vol.33 , Issue.8 , pp. 688-703
    • Stordal, B.1    Pavlakis, N.2    Davey, R.3
  • 26
    • 0344820767 scopus 로고    scopus 로고
    • Docetaxel and cisplatin: An active regimen in patients with locally advanced, recurrent or metastatic squamous cell carcinoma of the head and neck. Results of a phase II study of the EORTC Early Clinical Studies Group
    • Schoffski, P.; Catimel, G.; Planting, A.S.; Droz, J.P.; Verweij, J.; Schrijvers, D.; Gras, L.; Schrijvers, A.; Wanders, J.; Hanauske, A.R. Docetaxel and cisplatin: an active regimen in patients with locally advanced, recurrent or metastatic squamous cell carcinoma of the head and neck. Results of a phase II study of the EORTC Early Clinical Studies Group. Ann. Oncol. 1999, 10(1), 119-122.
    • (1999) Ann. Oncol , vol.10 , Issue.1 , pp. 119-122
    • Schoffski, P.1    Catimel, G.2    Planting, A.S.3    Droz, J.P.4    Verweij, J.5    Schrijvers, D.6    Gras, L.7    Schrijvers, A.8    Wanders, J.9    Hanauske, A.R.10
  • 27
    • 35548972994 scopus 로고    scopus 로고
    • Posner, M.R.; Hershock, D.M.; Blajman, C.R.; Mickiewicz, E.; Winquist, E.; Gorbounova, V.; Tjulandin, S.; Shin, D.M.; Cullen, K.; Ervin, T.J.; Murphy, B.A.; Raez, L.E.; Cohen, R.B.; Spaulding, M.; Tishler, R.B.; Roth, B.; Viroglio, R.C.; Venkatesan, V.; Romanov, I.; Agarwala, S.; Harter, K.W.; Dugan, M.; Cmelak, A.; Markoe, A.M.; Read, P.W.; Steinbrenner, L.; Colevas, A.D.; Norris, C.M., Jr.; Haddad, R.I. Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N. Engl. J. Med. 2007, 357(17), 1705-1715.
    • Posner, M.R.; Hershock, D.M.; Blajman, C.R.; Mickiewicz, E.; Winquist, E.; Gorbounova, V.; Tjulandin, S.; Shin, D.M.; Cullen, K.; Ervin, T.J.; Murphy, B.A.; Raez, L.E.; Cohen, R.B.; Spaulding, M.; Tishler, R.B.; Roth, B.; Viroglio, R.C.; Venkatesan, V.; Romanov, I.; Agarwala, S.; Harter, K.W.; Dugan, M.; Cmelak, A.; Markoe, A.M.; Read, P.W.; Steinbrenner, L.; Colevas, A.D.; Norris, C.M., Jr.; Haddad, R.I. Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N. Engl. J. Med. 2007, 357(17), 1705-1715.
  • 29
    • 66349099167 scopus 로고    scopus 로고
    • Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma
    • Mazumdar, A.; Henderson, Y.C.; El-Naggar, A.K.; Sen, S.; Clayman, G.L. Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma. Head Neck 2008, 31(5), 625-634.
    • (2008) Head Neck , vol.31 , Issue.5 , pp. 625-634
    • Mazumdar, A.1    Henderson, Y.C.2    El-Naggar, A.K.3    Sen, S.4    Clayman, G.L.5
  • 30
  • 32
    • 0028111802 scopus 로고
    • Has the breast cancer gene been found?
    • Vogelstein, B.; Kinzler, K.W. Has the breast cancer gene been found? Cell 1994, 79(1), 1-3.
    • (1994) Cell , vol.79 , Issue.1 , pp. 1-3
    • Vogelstein, B.1    Kinzler, K.W.2
  • 36
    • 4544374528 scopus 로고    scopus 로고
    • BRCA1 and BRCA2: 1994 and beyond
    • Narod, S.A.; Foulkes, W.D. BRCA1 and BRCA2: 1994 and beyond. Nat. Rev. Cancer 2004, 4(9), 665-676.
    • (2004) Nat. Rev. Cancer , vol.4 , Issue.9 , pp. 665-676
    • Narod, S.A.1    Foulkes, W.D.2
  • 37
    • 0034707053 scopus 로고    scopus 로고
    • In search of the tumour-suppressor functions of BRCA1 and BRCA2
    • Scully, R.; Livingston, D. In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature 2000, 408, 429-432.
    • (2000) Nature , vol.408 , pp. 429-432
    • Scully, R.1    Livingston, D.2
  • 38
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman, A.R. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 2002, 108(2), 171-182.
    • (2002) Cell , vol.108 , Issue.2 , pp. 171-182
    • Venkitaraman, A.R.1
  • 39
    • 13944281226 scopus 로고    scopus 로고
    • Molecular functions of BRCA1 in the DNA damage response
    • Scully, R.; Xie, A.; Nagaraju, G. Molecular functions of BRCA1 in the DNA damage response. Cancer Biol. Ther. 2004, 3(6), 521-527.
    • (2004) Cancer Biol. Ther , vol.3 , Issue.6 , pp. 521-527
    • Scully, R.1    Xie, A.2    Nagaraju, G.3
  • 40
    • 21644469743 scopus 로고    scopus 로고
    • BRCA1 and transcription
    • Lane, T.F. BRCA1 and transcription. Cancer Biol. Ther. 2004, 3(6), 528-533.
    • (2004) Cancer Biol. Ther , vol.3 , Issue.6 , pp. 528-533
    • Lane, T.F.1
  • 46
    • 33646409883 scopus 로고    scopus 로고
    • BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance
    • Chabalier, C.; Lamare, C.; Racca, C.; Privat, M.; Valette, A.; Larminat, F. BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance. Cell Cycle 2006, 5(9), 1001-1007.
    • (2006) Cell Cycle , vol.5 , Issue.9 , pp. 1001-1007
    • Chabalier, C.1    Lamare, C.2    Racca, C.3    Privat, M.4    Valette, A.5    Larminat, F.6
  • 47
    • 0035807219 scopus 로고    scopus 로고
    • Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway
    • Lafarge, S.; Sylvain, V.; Ferrara, M.; Bignon, Y.J. Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway. Oncogene 2001, 20(45), 6597-6606.
    • (2001) Oncogene , vol.20 , Issue.45 , pp. 6597-6606
    • Lafarge, S.1    Sylvain, V.2    Ferrara, M.3    Bignon, Y.J.4
  • 48
    • 0038031592 scopus 로고    scopus 로고
    • Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1
    • Zhou, C.; Smith, J.L.; Liu, J. Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1. Oncogene 2003, 22(16), 2396-2404.
    • (2003) Oncogene , vol.22 , Issue.16 , pp. 2396-2404
    • Zhou, C.1    Smith, J.L.2    Liu, J.3
  • 49
    • 0345254953 scopus 로고    scopus 로고
    • Enhanced sensitivity of peripheral blood lymphocytes from women carrying a BRCA1 mutation towards the mutagenic effects of various cytostatics
    • Trenz, K.; Lugowski, S.; Jahrsdorfer, U.; Jainta, S.; Vogel, W.; Speit, G. Enhanced sensitivity of peripheral blood lymphocytes from women carrying a BRCA1 mutation towards the mutagenic effects of various cytostatics. Mutat. Res. 2003, 544(2-3), 279-288.
    • (2003) Mutat. Res , vol.544 , Issue.2-3 , pp. 279-288
    • Trenz, K.1    Lugowski, S.2    Jahrsdorfer, U.3    Jainta, S.4    Vogel, W.5    Speit, G.6
  • 50
    • 34547504504 scopus 로고    scopus 로고
    • Rottenberg, S.; Nygren, A.O. H.; Pajic, M.; van Leeuwen, F.W. B.; van der Heijden, I.; van de Wetering, K.; Liu, X.; de Visser, K.E.; Gilhuijs, K.G.; van Tellingen, O.; Schouten, J.P.; Jonkers, J.; Borst, P. Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer. Proc. Natl. Acad. Sci. USA 2007, 0702955104.
    • Rottenberg, S.; Nygren, A.O. H.; Pajic, M.; van Leeuwen, F.W. B.; van der Heijden, I.; van de Wetering, K.; Liu, X.; de Visser, K.E.; Gilhuijs, K.G.; van Tellingen, O.; Schouten, J.P.; Jonkers, J.; Borst, P. Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer. Proc. Natl. Acad. Sci. USA 2007, 0702955104.
  • 51
    • 0036463949 scopus 로고    scopus 로고
    • Induction of ovarian cancer by defined multiple genetic changes in a mouse model system
    • Orsulic, S.; Li, Y.; Soslow, R.A.; Vitale-Cross, L.A.; Gutkind, J.S.; Varmus, H.E. Induction of ovarian cancer by defined multiple genetic changes in a mouse model system. Cancer Cell 2002, 1(1), 53-62.
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 53-62
    • Orsulic, S.1    Li, Y.2    Soslow, R.A.3    Vitale-Cross, L.A.4    Gutkind, J.S.5    Varmus, H.E.6
  • 52
    • 33749482498 scopus 로고    scopus 로고
    • A Mouse model for the molecular characterization of brca1-associated ovarian carcinoma
    • Xing, D.; Orsulic, S.A Mouse model for the molecular characterization of brca1-associated ovarian carcinoma. Cancer Res. 2006, 66(18), 8949-8953.
    • (2006) Cancer Res , vol.66 , Issue.18 , pp. 8949-8953
    • Xing, D.1    Orsulic, S.2
  • 53
    • 0034721885 scopus 로고    scopus 로고
    • BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines
    • Thangaraju, M.; Kaufmann, S.H.; Couch, F.J. BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines. J. Biol. Chem. 2000, 275(43), 33487-33496.
    • (2000) J. Biol. Chem , vol.275 , Issue.43 , pp. 33487-33496
    • Thangaraju, M.1    Kaufmann, S.H.2    Couch, F.J.3
  • 54
    • 0035253403 scopus 로고    scopus 로고
    • Mitotic checkpoints: From yeast to cancer
    • Wassmann, K.; Benezra, R. Mitotic checkpoints: from yeast to cancer. Curr. Opin. Genet. Dev. 2001, 11(1), 83-90.
    • (2001) Curr. Opin. Genet. Dev , vol.11 , Issue.1 , pp. 83-90
    • Wassmann, K.1    Benezra, R.2
  • 55
    • 10344230981 scopus 로고    scopus 로고
    • A requirement for breast-cancer-associated gene 1(BRCA1) in the spindle checkpoint
    • Wang, R.H.; Yu, H.; Deng, C.X. A requirement for breast-cancer-associated gene 1(BRCA1) in the spindle checkpoint. Proc. Natl. Acad. Sci. USA 2004, 101(49), 17108-17113.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.49 , pp. 17108-17113
    • Wang, R.H.1    Yu, H.2    Deng, C.X.3
  • 57
    • 1942474378 scopus 로고    scopus 로고
    • Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint
    • Sudo, T.; Nitta, M.; Saya, H.; Ueno, N.T. Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint. Cancer Res. 2004, 64(7), 2502-2508.
    • (2004) Cancer Res , vol.64 , Issue.7 , pp. 2502-2508
    • Sudo, T.1    Nitta, M.2    Saya, H.3    Ueno, N.T.4
  • 58
    • 0037586498 scopus 로고    scopus 로고
    • AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
    • Anand, S.; Penrhyn-Lowe, S.; Venkitaraman, A.R. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell 2003, 3(1), 51-62.
    • (2003) Cancer Cell , vol.3 , Issue.1 , pp. 51-62
    • Anand, S.1    Penrhyn-Lowe, S.2    Venkitaraman, A.R.3
  • 59
    • 22244478043 scopus 로고    scopus 로고
    • Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death
    • Weaver, B.A.; Cleveland, D.W. Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell 2005, 8(1), 7-12.
    • (2005) Cancer Cell , vol.8 , Issue.1 , pp. 7-12
    • Weaver, B.A.1    Cleveland, D.W.2
  • 60
    • 35349024501 scopus 로고    scopus 로고
    • Pujana, M.A.; Han, J.D.; Starita, L.M.; Stevens, K.N.; Tewari, M.; Ahn, J.S.; Rennert, G.; Moreno, V.; Kirchhoff, T.; Gold, B.; Assmann, V.; Elshamy, W.M.; Rual, J.F.; Levine, D.; Rozek, L.S.; Gelman, R.S.; Gunsalus, K.C.; Greenberg, R.A.; Sobhian, B.; Bertin, N.; Venkatesan, K.; yivi-Guedehoussou, N.; Sole, X.; Hernandez, P.; Lazaro, C.; Nathanson, K.L.; Weber, B.L.; Cusick, M.E.; Hill, D.E.; Offit, K.; Livingston, D.M.; Gruber, S.B.; Parvin, J.D.; Vidal, M. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat. Genet. 2007, 39(11), 1338-1349.
    • Pujana, M.A.; Han, J.D.; Starita, L.M.; Stevens, K.N.; Tewari, M.; Ahn, J.S.; Rennert, G.; Moreno, V.; Kirchhoff, T.; Gold, B.; Assmann, V.; Elshamy, W.M.; Rual, J.F.; Levine, D.; Rozek, L.S.; Gelman, R.S.; Gunsalus, K.C.; Greenberg, R.A.; Sobhian, B.; Bertin, N.; Venkatesan, K.; yivi-Guedehoussou, N.; Sole, X.; Hernandez, P.; Lazaro, C.; Nathanson, K.L.; Weber, B.L.; Cusick, M.E.; Hill, D.E.; Offit, K.; Livingston, D.M.; Gruber, S.B.; Parvin, J.D.; Vidal, M. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat. Genet. 2007, 39(11), 1338-1349.
  • 61
    • 0032573068 scopus 로고    scopus 로고
    • BRCA1 is associated with the centrosome during mitosis
    • Hsu, L.C.; White, R.L. BRCA1 is associated with the centrosome during mitosis. Proc. Natl. Acad. Sci. USA 1998, 95(22), 12983-12988.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.22 , pp. 12983-12988
    • Hsu, L.C.1    White, R.L.2
  • 62
    • 0035502955 scopus 로고    scopus 로고
    • Identification of a gamma-tubulin-binding domain in BRCA1
    • Hsu, L.C.; Doan, T.P.; White, R.L. Identification of a gamma-tubulin-binding domain in BRCA1. Cancer Res. 2001, 61(21), 7713-7718.
    • (2001) Cancer Res , vol.61 , Issue.21 , pp. 7713-7718
    • Hsu, L.C.1    Doan, T.P.2    White, R.L.3
  • 64
    • 25444455576 scopus 로고    scopus 로고
    • Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination
    • Sankaran, S.; Starita, L.M.; Groen, A.C.; Ko, M.J.; Parvin, J.D. Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination. Mol. Cell. Biol. 2005, 25(19), 8656-8668.
    • (2005) Mol. Cell. Biol , vol.25 , Issue.19 , pp. 8656-8668
    • Sankaran, S.1    Starita, L.M.2    Groen, A.C.3    Ko, M.J.4    Parvin, J.D.5
  • 65
    • 32144439074 scopus 로고    scopus 로고
    • Loss of BRCA1 expression may predict shorter time-to-progression in metastatic breast cancer patients treated with taxanes
    • Kurebayashi, J.; Yamamoto, Y.; Kurosumi, M.; Okubo, S.; Nomura, T.; Tanaka, K.; Sonoo, H. Loss of BRCA1 expression may predict shorter time-to-progression in metastatic breast cancer patients treated with taxanes. Anticancer Res. 2006, 26(1B), 695-701.
    • (2006) Anticancer Res , vol.26 , Issue.1 B , pp. 695-701
    • Kurebayashi, J.1    Yamamoto, Y.2    Kurosumi, M.3    Okubo, S.4    Nomura, T.5    Tanaka, K.6    Sonoo, H.7
  • 66
    • 28544450990 scopus 로고    scopus 로고
    • High thioredoxin expression is associated with resistance to docetaxel in primary breast cancer
    • Kim, S.J.; Miyoshi, Y.; Taguchi, T.; Tamaki, Y.; Nakamura, H.; Yodoi, J.; Kato, K.; Noguchi, S. High thioredoxin expression is associated with resistance to docetaxel in primary breast cancer. Clin. Cancer Res. 2005, 11(23), 8425-8430.
    • (2005) Clin. Cancer Res , vol.11 , Issue.23 , pp. 8425-8430
    • Kim, S.J.1    Miyoshi, Y.2    Taguchi, T.3    Tamaki, Y.4    Nakamura, H.5    Yodoi, J.6    Kato, K.7    Noguchi, S.8
  • 68
    • 0037288936 scopus 로고    scopus 로고
    • Frequent disease progression and early recurrence in patients with familial ovarian cancer primarily treated with paclitaxel and cis- or carboplatin (preliminary report)
    • Wojciechowska-Lacka, A.; Markowska, J.; Skasko, E.; Kruczek, A.; Steffen, J. Frequent disease progression and early recurrence in patients with familial ovarian cancer primarily treated with paclitaxel and cis- or carboplatin (preliminary report). Eur. J. Gynaecol. Oncol. 2003, 24(1), 21-24.
    • (2003) Eur. J. Gynaecol. Oncol , vol.24 , Issue.1 , pp. 21-24
    • Wojciechowska-Lacka, A.1    Markowska, J.2    Skasko, E.3    Kruczek, A.4    Steffen, J.5
  • 70
    • 33847355994 scopus 로고    scopus 로고
    • Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer
    • Lee, M.N.; Tseng, R.C.; Hsu, H.S.; Chen, J.Y.; Tzao, C.; Ho, W.L.; Wang, Y.C. Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer. Clin. Cancer Res. 2007, 13(3), 832-838.
    • (2007) Clin. Cancer Res , vol.13 , Issue.3 , pp. 832-838
    • Lee, M.N.1    Tseng, R.C.2    Hsu, H.S.3    Chen, J.Y.4    Tzao, C.5    Ho, W.L.6    Wang, Y.C.7
  • 72
    • 26444598043 scopus 로고    scopus 로고
    • ERCC1, hRad51, and BRCA1 protein expression in relation to tumour response and survival of stage III/IV NSCLC patients treated with chemotherapy
    • Wachters, F.M.; Wong, L.S. M.; Timens, W.; Kampinga, H.H.; Groen, H.J. M. ERCC1, hRad51, and BRCA1 protein expression in relation to tumour response and survival of stage III/IV NSCLC patients treated with chemotherapy. Lung Cancer 2005, 50(2), 211-219.
    • (2005) Lung Cancer , vol.50 , Issue.2 , pp. 211-219
    • Wachters, F.M.1    Wong, L.S.M.2    Timens, W.3    Kampinga, H.H.4    Groen, H.J.M.5
  • 73
    • 44349090911 scopus 로고    scopus 로고
    • ERCC1 and BRCA1 mRNA expression levels in metastatic malignant effusions is associated with chemosensitivity to cisplatin and/or docetaxel
    • Wang, L.; Wei, J.; Qian, X.; Yin, H.; Zhao, Y.; Yu, L.; Wang, T.; Liu, B. ERCC1 and BRCA1 mRNA expression levels in metastatic malignant effusions is associated with chemosensitivity to cisplatin and/or docetaxel. BMC Cancer 2008, 8(1), 97.
    • (2008) BMC Cancer , vol.8 , Issue.1 , pp. 97
    • Wang, L.1    Wei, J.2    Qian, X.3    Yin, H.4    Zhao, Y.5    Yu, L.6    Wang, T.7    Liu, B.8


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