Metallothionein inhibits doxorubicin-induced mitochondrial cytochrome c release and caspase-3 activation in cardiomyocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 298, Issue 2, 2001, Pages 461-468

  Wang, Guang Wu ^a   Klein, Jon B ^a,b   Kang, Y James ^a,c  

^a University of Louisville School of Medicine   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOCHROME C; DNA NUCLEOTIDYLEXOTRANSFERASE; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; METALLOTHIONEIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; HEART INJURY; HEART MUSCLE CELL; HEART PROTECTION; MITOCHONDRION; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANNEXIN A5; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CASPASE 3; CASPASES; CYTOCHROME C GROUP; DOXORUBICIN; ENZYME ACTIVATION; FLUORESCEIN-5-ISOTHIOCYANATE; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; METALLOTHIONEIN; MICE; MICE, TRANSGENIC; MITOCHONDRIA, HEART; MYOCARDIUM; REACTIVE OXYGEN SPECIES;

EID: 0034913884     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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