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Volumn 280, Issue 5 49-5, 2001, Pages

Inhibition of hypoxia/reoxygenation-induced apoptosis in metallothionein-overexpressing cardiomyocytes

Author keywords

Caspase 3 activation; Cell culture; Cell death; Cytochrome c release

Indexed keywords

CASPASE 3; CYTOCHROME C; LACTATE DEHYDROGENASE; METALLOTHIONEIN;

EID: 0035031486     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.5.h2292     Document Type: Article
Times cited : (67)

References (54)
  • 1
    • 0024523351 scopus 로고
    • Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein
    • Abel J and de Ruiter N. Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein. Toxicol Lett 47: 191-196, 1989.
    • (1989) Toxicol Lett , vol.47 , pp. 191-196
    • Abel, J.1    De Ruiter, N.2
  • 3
    • 0023192195 scopus 로고
    • Myocardial consequences of reperfusion
    • Becker LC and Ambrosio G. Myocardial consequences of reperfusion. Prog Cardiovasc Dis 30: 23-44, 1987.
    • (1987) Prog Cardiovasc Dis , vol.30 , pp. 23-44
    • Becker, L.C.1    Ambrosio, G.2
  • 4
    • 0015150006 scopus 로고
    • Requirements for spontaneous contractility in isolated adult mammalian heart muscle cells
    • Bloom S. Requirements for spontaneous contractility in isolated adult mammalian heart muscle cells. Exp Cell Res 69: 17-24, 1971.
    • (1971) Exp Cell Res , vol.69 , pp. 17-24
    • Bloom, S.1
  • 5
    • 0024455053 scopus 로고
    • Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury
    • Bolli R, Jeroudi MO, Patel BS, Aruoma OI, Halliwell B, Lai EK, and McCay PB. Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury. Circ Res 65: 607-622, 1989.
    • (1989) Circ Res , vol.65 , pp. 607-622
    • Bolli, R.1    Jeroudi, M.O.2    Patel, B.S.3    Aruoma, O.I.4    Halliwell, B.5    Lai, E.K.6    McCay, P.B.7
  • 6
    • 0021484980 scopus 로고
    • Effect of epinephrine and norepinephrine on zinc thionein levels and induction in rat liver
    • Brady FO and Helvig B. Effect of epinephrine and norepinephrine on zinc thionein levels and induction in rat liver. Am J Physlol Endocrinol Metab 247: E318-E322, 1984.
    • (1984) Am J Physlol Endocrinol Metab , vol.247
    • Brady, F.O.1    Helvig, B.2
  • 7
    • 0034671886 scopus 로고    scopus 로고
    • Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage
    • Cai L, Klein JB, and Kang YJ. Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage. J Biol Chem 275: 38957-38960, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 38957-38960
    • Cai, L.1    Klein, J.B.2    Kang, Y.J.3
  • 9
    • 0026336011 scopus 로고
    • Determination of metallothionein in tissue by cadmium-hemoglobin affinity assay
    • Eaton DL and Cherian MG. Determination of metallothionein in tissue by cadmium-hemoglobin affinity assay. Methods Enzymol 205: 83-88, 1991.
    • (1991) Methods Enzymol , vol.205 , pp. 83-88
    • Eaton, D.L.1    Cherian, M.G.2
  • 10
    • 0029129279 scopus 로고
    • Metabolic disturbances during myocardial ischemia and reperfusion
    • Ferrari R. Metabolic disturbances during myocardial ischemia and reperfusion. Am J Cardiol 76: 17B-24B, 1995.
    • (1995) Am J Cardiol , vol.76
    • Ferrari, R.1
  • 11
    • 0029956792 scopus 로고    scopus 로고
    • Apoptosis in ischemic and reperfused rat myocardium
    • Fliss H and Gattinger D. Apoptosis in ischemic and reperfused rat myocardium. Cire Res 79: 949-956, 1996.
    • (1996) Cire Res , vol.79 , pp. 949-956
    • Fliss, H.1    Gattinger, D.2
  • 12
    • 0343883506 scopus 로고    scopus 로고
    • Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation
    • Garcia-Ruiz C, Colell A, Paris R, and Fernandez-Checa JC. Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation. FASEB J 14: 847-858, 2000.
    • (2000) FASEB J , vol.14 , pp. 847-858
    • Garcia-Ruiz, C.1    Colell, A.2    Paris, R.3    Fernandez-Checa, J.C.4
  • 13
    • 0032777020 scopus 로고    scopus 로고
    • Apoptosis in myocardial ischemia-reperfusion
    • Gottlieb RA and Engler RL. Apoptosis in myocardial ischemia-reperfusion. Ann NY Acad Sci 874: 412-426, 1999.
    • (1999) Ann NY Acad Sci , vol.874 , pp. 412-426
    • Gottlieb, R.A.1    Engler, R.L.2
  • 14
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR and Reed JC. Mitochondria and apoptosis. Science 281: 1309-1312, 1998.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 16
    • 0022555879 scopus 로고
    • Metallothionein
    • Hamer DH. Metallothionein. Annu Rev Biochem 55: 913-951, 1986.
    • (1986) Annu Rev Biochem , vol.55 , pp. 913-951
    • Hamer, D.H.1
  • 17
    • 0028196994 scopus 로고
    • Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants
    • Jeroudi MO, Hartley CJ, and Bolli R. Myocardial reperfusion injury: role of oxygen radicals and potential therapy with antioxidants. Am J Cardiol 73: 2B-7B, 1994.
    • (1994) Am J Cardiol , vol.73
    • Jeroudi, M.O.1    Hartley, C.J.2    Bolli, R.3
  • 18
    • 0026353521 scopus 로고
    • Overview of metallothionein
    • Kagi JHR. Overview of metallothionein. Methods Enzymol 205: 613-626, 1991.
    • (1991) Methods Enzymol , vol.205 , pp. 613-626
    • Kagi, J.H.R.1
  • 20
    • 0032756355 scopus 로고    scopus 로고
    • The antioxidant function of metallothionein in the heart
    • Kang YJ. The antioxidant function of metallothionein in the heart. Proc Soc Exp Biol Med 222: 263-273, 1999.
    • (1999) Proc Soc Exp Biol Med , vol.222 , pp. 263-273
    • Kang, Y.J.1
  • 21
    • 0030803635 scopus 로고    scopus 로고
    • Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity
    • Kang YJ, Chen Y, Yu A, Voss-McCowan M, and Epstein PN. Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity. J Clin Invest 100: 1501-1506, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 1501-1506
    • Kang, Y.J.1    Chen, Y.2    Yu, A.3    Voss-McCowan, M.4    Epstein, P.N.5
  • 22
    • 0032955692 scopus 로고    scopus 로고
    • Metallothionein inhibits ischemia-reperfusion injury in mouse heart
    • Kang YJ, Li G, and Saari JT. Metallothionein inhibits ischemia-reperfusion injury in mouse heart. Am J Physiol Heart Circ Physiol 276: H993-H997, 1999.
    • (1999) Am J Physiol Heart Circ Physiol , vol.276
    • Kang, Y.J.1    Li, G.2    Saari, J.T.3
  • 23
    • 0034608083 scopus 로고    scopus 로고
    • Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases
    • Kang YJ, Zhou ZX, Wang GW, Buridi A, and Klein JB. Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. J Biol Chem 275: 13690-13698, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 13690-13698
    • Kang, Y.J.1    Zhou, Z.X.2    Wang, G.W.3    Buridi, A.4    Klein, J.B.5
  • 24
    • 0034079383 scopus 로고    scopus 로고
    • Metallothionein inhibits myocardial apoptosis in copper-deficient mice: Role of atrial natriuretic peptide
    • Kang YJ, Zhou ZX, Wu HY, Wang GW, Saari JT, and Klein JB. Metallothionein inhibits myocardial apoptosis in copper-deficient mice: role of atrial natriuretic peptide. Lab Invest 80: 745-757, 2000.
    • (2000) Lab Invest , vol.80 , pp. 745-757
    • Kang, Y.J.1    Zhou, Z.X.2    Wu, H.Y.3    Wang, G.W.4    Saari, J.T.5    Klein, J.B.6
  • 25
    • 0030843575 scopus 로고    scopus 로고
    • L inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
    • L inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res 57: 3115-3120, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3115-3120
    • Kim, C.N.1    Wang, X.2    Huang, Y.3    Ibrado, A.M.4    Liu, L.5    Fang, G.6    Bhalla, K.7
  • 27
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Almemri ES, and Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91: 479-489, 1997.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Almemri, E.S.6    Wang, X.7
  • 28
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R, and Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86: 147-157, 1996.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 29
    • 0031930041 scopus 로고    scopus 로고
    • Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction
    • Lucas DT and Szweda LI. Cardiac reperfusion injury: aging, lipid peroxidation, and mitochondrial dysfunction. Proc Natl Acad Sci USA 95: 510-514, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 510-514
    • Lucas, D.T.1    Szweda, L.I.2
  • 30
    • 0025369854 scopus 로고
    • Myocardial ischemia, reperfusion and free radical injury
    • Lucchesi BR. Myocardial ischemia, reperfusion and free radical injury. Am J Cardiol 65: 141-231, 1990.
    • (1990) Am J Cardiol , vol.65 , pp. 141-231
    • Lucchesi, B.R.1
  • 31
    • 0033617296 scopus 로고    scopus 로고
    • Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes
    • Malhotra R and Brosius FC III. Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes. J Biol Chem 274: 12567-12575, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 12567-12575
    • Malhotra, R.1    Brosius F.C. III2
  • 32
    • 0021690255 scopus 로고
    • Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol
    • Manning AS, Coltart DJ, and Hearse DJ. Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol. Circ Res 55: 544-548, 1984.
    • (1984) Circ Res , vol.55 , pp. 544-548
    • Manning, A.S.1    Coltart, D.J.2    Hearse, D.J.3
  • 33
    • 0023893395 scopus 로고
    • Specific reduction of toxic side effects of adriamycin by induction of metallothionein in mice
    • Naganuma A, Satoh M, and Imura N. Specific reduction of toxic side effects of adriamycin by induction of metallothionein in mice. Jpn J Cancer Res 79: 406-411, 1988.
    • (1988) Jpn J Cancer Res , vol.79 , pp. 406-411
    • Naganuma, A.1    Satoh, M.2    Imura, N.3
  • 35
    • 0032502855 scopus 로고    scopus 로고
    • Activation of caspase triggered by cytochrome c in vitro
    • Pan G, Humke EW, and Dixit VM. Activation of caspase triggered by cytochrome c in vitro. FEBS Lett 426: 151-154, 1998.
    • (1998) FEBS Lett , vol.426 , pp. 151-154
    • Pan, G.1    Humke, E.W.2    Dixit, V.M.3
  • 37
    • 0032409943 scopus 로고    scopus 로고
    • Mechanisms of cell death in hypoxia/reoxygenation injury
    • Saikumar P, Dong Z, Weinberg JM, and Venkatachalam MA. Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene 17: 3341-3349, 1998.
    • (1998) Oncogene , vol.17 , pp. 3341-3349
    • Saikumar, P.1    Dong, Z.2    Weinberg, J.M.3    Venkatachalam, M.A.4
  • 38
    • 0027979893 scopus 로고
    • Differential induction of metallothionein synthesis by interleukin-6 and tumor necrosis factor-alpha in rat tissues
    • Sato M, Sasaki M, and Hojo H. Differential induction of metallothionein synthesis by interleukin-6 and tumor necrosis factor-alpha in rat tissues. Int J Immunopharmacol 16: 187-195, 1994.
    • (1994) Int J Immunopharmacol , vol.16 , pp. 187-195
    • Sato, M.1    Sasaki, M.2    Hojo, H.3
  • 39
    • 0023845630 scopus 로고
    • Metallothionein induction prevents toxic side effects of cisplatin and adriamycin used in combination
    • Satoh M, Naganuma A, and Imura N. Metallothionein induction prevents toxic side effects of cisplatin and adriamycin used in combination. Cancer Chemother Pharmacol 21: 176-178, 1988.
    • (1988) Cancer Chemother Pharmacol , vol.21 , pp. 176-178
    • Satoh, M.1    Naganuma, A.2    Imura, N.3
  • 40
    • 0023709360 scopus 로고
    • Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia-reperfusion injury in canine heart
    • Tamura Y, Chi L, Driscoll EJ Jr, Hott PT, Freeman BM, Gallagher KP, and Lucchesi BR. Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia-reperfusion injury in canine heart. Circ Res 63: 944-959, 1988.
    • (1988) Circ Res , vol.63 , pp. 944-959
    • Tamura, Y.1    Chi, L.2    Driscoll E.J., Jr.3    Hott, P.T.4    Freeman, B.M.5    Gallagher, Kp.6    Lucchesi, B.R.7
  • 41
    • 0026346240 scopus 로고
    • Toxicological significance of metallothionein
    • Templeton DM and Cherian MG. Toxicological significance of metallothionein. Methods Enzymol 205: 11-24, 1991.
    • (1991) Methods Enzymol , vol.205 , pp. 11-24
    • Templeton, D.M.1    Cherian, M.G.2
  • 42
    • 0022908892 scopus 로고
    • Inhibition of cell membrane lipid peroxidation by cadmium- and zinc-metallothionein
    • Thomas JP, Bachowski GL, and Girotti AW. Inhibition of cell membrane lipid peroxidation by cadmium- and zinc-metallothionein. Biochim Biophys Acta 884: 448-461, 1986.
    • (1986) Biochim Biophys Acta , vol.884 , pp. 448-461
    • Thomas, J.P.1    Bachowski, G.L.2    Girotti, A.W.3
  • 43
    • 0021944046 scopus 로고
    • Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals
    • Thornalley PJ and Vasak M. Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. Biochim Biophys Acta 827: 36-44, 1985.
    • (1985) Biochim Biophys Acta , vol.827 , pp. 36-44
    • Thornalley, P.J.1    Vasak, M.2
  • 44
    • 0031811526 scopus 로고    scopus 로고
    • Metallothionein expression prevents apoptosis: A study with antisense phosphorothioate oligodeoxynucleotides in human T cell line
    • Tsangaris GT and Tzortzatou-Statopoulou F. Metallothionein expression prevents apoptosis: a study with antisense phosphorothioate oligodeoxynucleotides in human T cell line. Anticancer Res 18: 2423-2433, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 2423-2433
    • Tsangaris, G.T.1    Tzortzatou-Statopoulou, F.2
  • 45
    • 0033535974 scopus 로고    scopus 로고
    • Signaling pathway in reactive oxygen species-induced cardiomyocyte apoptosis
    • von Harsdorf R, Li PF, and Dietz R. Signaling pathway in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation 99: 2934-2941, 1999.
    • (1999) Circulation , vol.99 , pp. 2934-2941
    • Von Harsdorf, R.1    Li, P.F.2    Dietz, R.3
  • 46
    • 0033054346 scopus 로고    scopus 로고
    • Inhibition of doxorubicin toxicity in cultured neonatal mouse cardiomyocytes with elevated metallothionein levels
    • Wang GW and Kang YJ. Inhibition of doxorubicin toxicity in cultured neonatal mouse cardiomyocytes with elevated metallothionein levels. J Pharmacol Exp Ther 288: 938-944, 1999.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 938-944
    • Wang, G.W.1    Kang, Y.J.2
  • 48
    • 0026332817 scopus 로고
    • A primary culture system of adult rat heart cells for the study of toxicologic agent
    • Welder AA, Grant R, Bradlaw J, and Acosta D. A primary culture system of adult rat heart cells for the study of toxicologic agent. In Vitro Cell Dev Biol 27A: 921-926, 1991.
    • (1991) In Vitro Cell Dev Biol , vol.27 A , pp. 921-926
    • Welder, A.A.1    Grant, R.2    Bradlaw, J.3    Acosta, D.4
  • 49
    • 0032463529 scopus 로고    scopus 로고
    • Inhibition of buthionein sulfoximine-enhanced doxorubicin toxicity in metallothionein overexpressing transgenic mouse heart
    • Wu HY and Kang YJ. Inhibition of buthionein sulfoximine-enhanced doxorubicin toxicity in metallothionein overexpressing transgenic mouse heart. J Pharmacol Exp Ther 287: 515-520, 1998.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 515-520
    • Wu, H.Y.1    Kang, Y.J.2
  • 50
    • 0032693943 scopus 로고    scopus 로고
    • Hypoxia-reoxygenation-induced apoptosis in cultured adult rat myocytes and the protective effect of platelets and transforming growth factor-β1
    • Yang BC, Zander DS, and Mehta JL. Hypoxia-reoxygenation-induced apoptosis in cultured adult rat myocytes and the protective effect of platelets and transforming growth factor-β1. J Pharmacol Exp Ther 291: 733-738, 1999.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 733-738
    • Yang, B.C.1    Zander, D.S.2    Mehta, J.L.3
  • 53
    • 0033838708 scopus 로고    scopus 로고
    • Immunocytochemical localization of metallothionein and its relation to doxorubicin toxicity in transgenic mouse heart
    • Zhou ZX and Kang YJ. Immunocytochemical localization of metallothionein and its relation to doxorubicin toxicity in transgenic mouse heart. Am J Pathol 156: 1653-1662, 2000.
    • (2000) Am J Pathol , vol.156 , pp. 1653-1662
    • Zhou, Z.X.1    Kang, Y.J.2
  • 54
    • 0033542780 scopus 로고    scopus 로고
    • Caspase-8 mediates caspase-3 activation and cytochrome c release during singlet oxygen-induced apoptosis of HL-60 cells
    • Zhuang S, Lynch MC, and Kochevar IE. Caspase-8 mediates caspase-3 activation and cytochrome c release during singlet oxygen-induced apoptosis of HL-60 cells. Exp Cell Res 250: 203-212, 1999.
    • (1999) Exp Cell Res , vol.250 , pp. 203-212
    • Zhuang, S.1    Lynch, M.C.2    Kochevar, I.E.3


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