Myocyte death in streptozotocin-induced diabetes in rats is angiotensin II- dependent

Laboratory Investigation

Volumn 80, Issue 4, 2000, Pages 513-527

  Fiordaliso, Fabio ^a   Li, Baosheng ^a   Latini, Roberto ^b   Sonnenblick, Edmund H ^a   Anversa, Piero ^a   Leri, Annarosa ^a   Kajstura, Jan ^a,c  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c Vosburgh Pavilion ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSINOGEN; RENIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CELL DEATH; CELL LOSS; CELL VIABILITY; CELL VOLUME; CONTROLLED STUDY; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; STREPTOZOCIN DIABETES;

EID: 0034050078     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780057     Document Type: Article

References (47)

1. Anversa P, Hiler B, Ricci R, Guideri G, and Olivetti G (1986). Myocyte cell loss and myocyte hypertrophy in the aging rat heart. J Am Coll Cardiol 8:1441-1448.
2. Anversa P and Kajstura J (1998). Myocyte cell death in the diseased heart. Circ Res 82:1231-1233.
3. Anversa P, Leri A, Beltrami CA, Guerra S, and Kajstura J (1998). Myocyte death and growth in the failing heart. Lab Invest 78:676-786.
4. Anversa P, Zhang X, Li P, and Capasso JM (1992). Chronic coronary artery constriction leads to moderate myocyte loss and left ventricular dysfunction and failure in rats. J Clin Invest 89:618-629.
5. Baker KM, Booz GW, and Dostal DE (1992). Cardiac actions of angiotensin II: Role of an intracardiac renin-angiotensin system. Annu Rev Physiol 54:227-241.
6. Bell DSH (1995). Diabetic cardiomyopathy: A unique entity or a complication of coronary artery disease? Diabetes Care 18:708-714.
7. Beltrami CA, Finato N, Rocco M, Feruglio GA, Puricelli C, Cigola E, Quaini F, Sonnenblick EH, Olivetti G, and Anversa P (1994). Structural basis of end-stage failure in ischemic cardiomyopathy in humans. Circulation 89:151-163.
8. Cheng W, Kajstura J, Nitahara JA, Li B, Reiss K, Liu Y, Clark WA, Krajewski S, Reed JC, Olivetti G, and Anversa P. (1996a). Programmed myocyte cell death affects the viable myocardium after infarction in rats. Exp Cell Res 226:316-327.
9. Cheng W, Reiss K, Li P, Chun MJ, Kajstura J, Olivetti G, and Anversa P. (1996b). Aging does not affect the activation of the myocyte insulin-like growth factor-1 autocrine system after infarction and ventricular failure in Fischer 344 rats. Circ Res 78:536-546.
10. Cohn JN, Bristow MR, Chien KR, Colucci WS, Frazier OH, Leinwand LA, Lorell BH, Moss AJ, Sonnenblick EH, Walsh RA, Mockrin SC, and Reinlib L (1997). Report of the National Heart, Lung, and Blood Institute special emphasis panel on heart failure research. Circulation 95:766-770.
11. Didenko VV and Hornsby PJ (1996). Presence of double-strand breaks with single-base 3′ overhangs in cells undergoing apoptosis but not necrosis. J Cell Biol 135:1369-1376.
12. Didenko VV, Tunstead JR, and Hornsby PJ (1998). Biotinlabeled hairpin oligonucleotides. Probes to detect double-strand breaks in DNA in apoptotic cells. Am J Pathol 152: 897-902.
13. Fein FS and Sonnenblick EH (1985). Diabetic cardiomyopathy. Prog Cardiovasc Dis 27:255-270.
14. Fuller JH, Shipley MJ, Rose G, Jarret RJ, and Keen H (1980). Coronary heart disease risk and impaired glucose tolerance: The Whitehall Study. Lancet i: 1373-1376.
15. Garcia MJ, McNamara PM, Gordon T, and Kannell WB (1974). Morbidity and mortality in diabetics in the Framingham population: Sixteen-year follow-up study. Diabetes 23: 105-111.
16. Gerschenson LE and Rotello RJ (1992). Apoptosis: A different type of cell death. FASEB J 6:2450-2455.
17. Hardin NJ (1996). The myocardial and vascular pathology of diabetic cardiomyopathy. Coron Artery Dis 7:99-108.
18. Haunstetter A and Izumo S (1998). Apoptosis: Basic mechanisms and implications for cardiovascular disease. Circ Res 82:1111-1129.
19. Kajstura J, Cigola E, Malhotra A, Li P, Cheng W, Meggs LG, and Anversa P (1997). Angiotensin II induces apoptosis of adult ventricular myocytes in vitro. J Mol Cell Cardiol 29:859-870.
20. Kajstura J, Zhang X, Reiss K, Szoke E, Li P, Lagrasta C, Cheng W, Darzynkiewicz Z, Olivetti G, and Anversa P (1994). Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats. Circ Res 74:383-400.
21. Kannel WB and McGee DL (1979). Diabetes and cardiovascular disease: The Framingham study. JAMA 241:2035-2038.
22. Leri A, Claudio PP, Li Q, Wang X, Reiss K, Wang S, Malhotra A, Kajstura J, and Anversa P (1998). Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest 101:1326-1342.
23. Leri A, Liu Y, Claudio PP, Kajstura J, Wang X, Wang S, Kang P, Malhotra A, and Anversa P (1999a). Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis. Am J Pathol 154:567-580.
24. Leri A, Liu Y, Wang X, Kajstura J, Malhotra A, Meggs LG, and Anversa P (1999b). Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice. Circ Res 84:752-762.
25. Lewis EJ, Hunsicker LG, Bain RP, and Rohde RD (1993). The effect of angiotensin-coverting enzyme inhibition on diabetic nephropathy. N Engl J Med 329:1456-1462.
26. Li Z, Bing OHL, Long X, Robinson KG, and Lakatta EG (1997a). Increased cardiomyocyte apoptosis during the transition of heart failure in the spontaneously hypertensive rat. Am J Physiol 272:H2313-H2319.
27. Li Q, Li B, Wang X, Leri A, Jana KP, Liu Y, Kajstura J, Baserga R, and Anversa P (1997b). Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest 100:1991-1999.
28. Li B, Setoguchi M, Wang X, Andreoli AM, Leri A, Malhotra A, Kajstura J, and Anversa P (1999). Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart. Circ Res 84:1007-1019.
29. Liu Y, Leri A, Li B, Wang X, Cheng W, Kajstura J, and Anversa P (1998). Angiotensin II stimulation in vitro induces hypertrophy of normal and postinfarcted ventricular myocytes. Circ Res 82:1145-1159.
30. Malhotra A, Penpargkul S, Fein FS, Sonnenblick EH, and Scheuer J (1981). The effect of streptozotocin induced diabetes in rats on cardiac contractile proteins. Circ Res 49: 1243-1250.
31. Malhotra A, Reich D, Reich D, Nakouzi A, Sanghi V, Geenen DL, and Buttrick PM (1997). Experimental diabetes is associated with functional activation of protein kinase C∈ and phosphorylation of troponin I in the heart, which are prevented by angiotensin II receptor blockade. Circ Res 81: 1027-1033.
32. Meng QC, Durand J, Chen YF, and Oparil S (1993). Simplified method for quantitation of angiotensin peptides in tissue. J Chromatogr 614:19-25.
33. Oemar BS, Foellmer HG, Hodgdon-Anandant L, and Rosenzweig SA (1991). Regulation of insulin-like growth factor I receptors in diabetic mesangial cells. J Biol Chem 266:2369-2373.
34. Olivetti G, Giordano G, Corradi D, Melissari M, Lagrasta C, Gambert SR, and Anversa P (1995). Gender differences and aging: Effects on the human heart. J Am Coll Cardiol 26: 1068-1079.
35. Olivetti G, Melissari M, Capasso JM, and Anversa P (1991). Cardiomyopathy of the aging human heart: Myocyte loss and reactive cellular hypertrophy. Circ Res 68:1560-1568.
36. Pfeffer MA and Braunwald E (1990). Ventricular remodeling after myocardial infarction. Circulation 81:1161-1172.
37. Pierce GN and Dhalla NS (1981). Cardiac myofibrillar ATPase activity in diabetic rats. J Mol Cell Cardiol 13:1063-1069.
38. Pierzchalski P, Reiss K, Cheng W, Cirielli C, Kajstura J, Nitahara JA, Rizk M, Capogrossi MC, and Anversa P (1997). p53 induces myocyte apoptosis via the activation of the renin-angiotensin system. Exp Cell Res 234:57-65.
39. Rockman HA, Wachhorst SP, Mao L, and Ross J (1994). ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice. Am J Physiol 266:H2468-H2475.
40. Rodrigues B, Cam MC, and McNeill JH (1998). Metabolic disturbances in diabetic cardiomyopathy. Mol Cell Biochem 180:53-57.
41. Rodrigues B and McNeill JH (1992). The diabetic heart: Metabolic causes for the development of a cardiomyopathy. Cardiovasc Res 26:913-922.
42. Shaw P, Freeman J, Bovey R, and Iggo R (1996). Regulation of specific DNA binding by p53: Evidence for a role for O-glycosylation and charged residues at the carboxyterminus. Oncogene 12:921-930.
43. 1-receptor blockade on progression of left ventricular dysfunction in dogs with heart failure. Am J Physiol 276:H1385-H1392.
44. Wallenstein S, Zucker CL, and Fleiss JL (1980). Some statistical methods useful in circulation research. Circ Res 47:1-9.
45. Weber KT and Brilla CG (1991). Pathological hypertrophy and cardiac interstitium. Circulation 83:1849-1865.
46. Zuanetti G, Latini R, Maggioni AP, Franzosi MG, Santoro L, and Tognoni G (1997). Effect of the ACE inhibitor lisinopril on mortality in diabetic patients with acute myocardial infarction. Circulation 96:4239-4245.
47. Zutz R, Dunn BR, Meyer TW, Anderson S, Renneker H, and Brenner BM (1986). Prevention of diabetic glomerulopathy by pharmacological amelioration of capillary hypertension. J Clin Invest 77:1925-1930.