Fast, adaptive evolution at a bacterial host-resistance locus: The PFam54 gene array in Borrelia burgdorferi

Gene

Volumn 445, Issue 1-2, 2009, Pages 26-37

  Wywial, Ewa ^a,b   Haven, James ^a,c   Casjens, Sherwood R ^d   Hernandez, Yozen A ^c   Singh, Shaneen ^a,b   Mongodin, Emmanuel F ^e   Fraser Liggett, Claire M ^e   Luft, Benjamin J ^f   Schutzer, Steven E ^g   Qiu, Wei Gang ^a,c  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^f STONY BROOK UNIVERSITY   (United States)

^g RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Borrelia burgdorferi; Complement regulator acquiring surface protein 1; cspA; Factor H; Immune evasion; Lyme disease

Indexed keywords

BACTERIAL PROTEIN; MEMBRANE PROTEIN; PROTEIN PFAM54; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BORRELIA BURGDORFERI; GENE DUPLICATION; GENE FUNCTION; GENE LOCUS; GENE LOSS; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC CODE; GENETIC POLYMORPHISM; HOST RESISTANCE; INNATE IMMUNITY; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SYNTENY; TANDEM REPEAT;

ADAPTATION, BIOLOGICAL; BACTERIAL INFECTIONS; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; BORRELIA BURGDORFERI; COMPLEMENT FACTOR H; EVOLUTION, MOLECULAR; GENES, BACTERIAL; GENETIC VARIATION; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; LYME DISEASE; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PHYLOGENY; SEQUENCE HOMOLOGY, NUCLEIC ACID; TIME FACTORS;

BACTERIA (MICROORGANISMS); BORRELIA BURGDORFERI;

EID: 67650694737     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2009.05.017     Document Type: Article

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