A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi

Nature Structural and Molecular Biology

Volumn 12, Issue 3, 2005, Pages 276-277

  Cordes, Frank S ^a   Roversi, Pietro ^a   Kraiczy, Peter ^c   Simon, Markus M ^d   Brade, Volker ^c   Jahraus, Oliver ^e   Wallis, Russell ^b   Skerka, Christine ^f   Zipfel, Peter F ^f   Wallich, Reinhard ^e   Lea, Susan M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^d MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f HANS KNÖLL INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT FACTOR H; COMPLEMENT FACTOR H BBCRASP 1; HOMODIMER; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; COMPLEMENT FACTOR H, HUMAN; COMPLEMENT REGULATOR ACQUIRING SURFACE PROTEINS, BORRELIA BURGDORFERI; COMPLEMENT REGULATOR-ACQUIRING SURFACE PROTEINS, BORRELIA BURGDORFERI; FHL 1 (FACTOR H LIKE) PROTEIN, HUMAN; FHL-1 (FACTOR H-LIKE) PROTEIN, HUMAN; MEMBRANE PROTEIN; PLASMA PROTEIN;

ARTICLE; BACTERIAL STRAIN; BORRELIA BURGDORFERI; CRYSTAL STRUCTURE; DRUG DESIGN; IXODES; LYME DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STRUCTURE; CHEMISTRY; DIMERIZATION; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

ACARI; BACTERIA (MICROORGANISMS); BORRELIA BURGDORFERI; IXODES; SPIROCHAETALES;

BACTERIAL PROTEINS; BLOOD PROTEINS; COMPLEMENT FACTOR H; DIMERIZATION; LYME DISEASE; MEMBRANE PROTEINS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY;

EID: 20244363221     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb902     Document Type: Article

References (14)

1. Barbour, A.G. & Hayes, S.F. Microbiol. Rev. 50, 381-400 (1986).
2. Steere, A.C. N. Engl. J. Med. 321, 586-596 (1989).
3. Wang, G.Q., van Dam, A.P., Schwartz, I. & Dankert, J. Clin. Microbiol. Rev. 12, 633-653 (1999).
4. Centers for Disease Control and Prevention (CDC). MMWR Morb. Mortal. Wkly Rep. 51, 29-31 (2002).
5. O'Connell, S., Granstrom, M., Gray, J.S. & Stanek, G. Zentralbi. Bakteriol. 287, 229-240 (1998).
6. Stanek, G. & Strle, F. Lancet 362, 1639-1647 (2003).
7. Kraiczy, P. et al. J. Biol. Chem. 279, 2421-2429 (2004).
8. Kraiczy, P., Skerka, C., Brade, V. & Zipfel, P.F. Infect. Immun. 69, 7800-7809 (2001).
9. Kraiczy, P., Skerka, C., Kirschfink, M., Brade, V. & Zipfel, P.F. Eur. J. Immunol. 31, 1674-1684 (2001).
10. Kraiczy, P., Skerka, C., Kirschfink, M., Zipfel, P.F. & Brade, V. Int. Immunopharmacol. 1, 393-401 (2001).
11. Lea, S.M. et al. J. Biol. Chem. 273, 30443-30447 (1998).
12. Cordes, F.S. et al. Acta Crystallogr. D 60, 929-932 (2004).
13. Holm, L. & Sander, C. J. Mol. Biol. 233, 123-138 (1993).
14. Lesk, A. Introduction to Protein Science: Architecture, Function, and Genomics (Oxford Univ. Press, Oxford, 2004).