Substituted cysteine accessibility method analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F)

Journal of Biological Chemistry

Volumn 284, Issue 25, 2009, Pages 17281-17292

  Slugoski, Melissa D ^a   Ng, Amy M L ^a   Yao, Sylvia Y M ^a   Lin, Colin C ^a   Mulinta, Ras ^a   Cass, Carol E ^a,b   Baldwin, Stephen A ^c   Young, James D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b CROSS CANCER INSTITUTE   (Canada)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CONCENTRATIVE NUCLEOSIDE TRANSPORTERS; ELECTROCHEMICAL GRADIENTS; EXTRACELLULAR; GLYCOSYLATED; HETEROLOGOUS EXPRESSION; INTEGRAL MEMBRANE; METHOD ANALYSIS; TOPOLOGY MODEL; TRANSMEMBRANE HELICES; XENOPUS OOCYTE;

SODIUM;

BIOMOLECULES;

ALANINE; ASPARAGINE; CHLOROMERCURIBENZENESULFONIC ACID; CONCENTRATIVE NUCLEOSIDE TRANSPORTER 3; CYSTEINE; GLUTAMIC ACID; GLYCINE; METHIONINE; NUCLEOSIDE TRANSPORTER; PHENYLALANINE; SERINE; TYROSINE; UNCLASSIFIED DRUG; VALINE;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HETEROLOGOUS EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STRUCTURE;

4-CHLOROMERCURIBENZENESULFONATE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CYSTEINE; FEMALE; HUMANS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEOSIDES; OOCYTES; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; URIDINE; XENOPUS LAEVIS;

EUKARYOTA;

EID: 67650541847     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.009704     Document Type: Article

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