Conserved glutamate residues are critically involved in Na +/nucleoside cotransport by human concentrative nucleoside transporter 1 (hCNT1)

Journal of Biological Chemistry

Volumn 282, Issue 42, 2007, Pages 30607-30617

  Yao, Sylvia Y M ^a   Ng, Amy M L ^a   Slugoski, Melissa D ^a   Smith, Kyla M ^a   Mulinta, Ras ^a   Karpinski, Edward ^a   Cass, Carol E ^a,b   Baldwin, Stephen A ^c   Young, James D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b CROSS CANCER INSTITUTE   (Canada)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RESIDUES; HUMAN CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1 (HCNT1); INTRACELLULAR MEMBRANES; XENOPUS OOCYTES;

AMINO ACIDS; CELL MEMBRANES; CHARGE TRANSFER; ENZYME INHIBITION; MUTAGENESIS; NUCLEOTIDES;

GENE EXPRESSION;

ASPARTIC ACID; CARRIER PROTEIN; GLUTAMIC ACID; MUTANT PROTEIN; NUCLEOSIDE TRANSPORTER 1; SODIUM ION; UNCLASSIFIED DRUG; URIDINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL SURFACE; CHANNEL GATING; FEMALE; GENETIC CONSERVATION; NONHUMAN; NUCLEOSIDE TRANSPORT; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; SODIUM TRANSPORT; TRANSPORT KINETICS; WILD TYPE; XENOPUS;

4-CHLOROMERCURIBENZENESULFONATE; AMINO ACID SUBSTITUTION; AMINO ACIDS; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELL MEMBRANE; ENZYME INHIBITORS; ETHYL METHANESULFONATE; HUMANS; INDICATORS AND REAGENTS; ION CHANNEL GATING; KINETICS; MEMBRANE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; OOCYTES; RECOMBINANT PROTEINS; SODIUM; URIDINE; XENOPUS LAEVIS;

EID: 35649019182     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703285200     Document Type: Article

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