메뉴 건너뛰기




Volumn 20, Issue 13, 2009, Pages 3125-3141

Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the ph regulation of endocytic organelles

Author keywords

[No Author keywords available]

Indexed keywords

COUNTERION; DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; TRANSFERRIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 67650436090     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E09-01-0061     Document Type: Article
Times cited : (68)

References (101)
  • 1
    • 0025784535 scopus 로고
    • Defective acidification of intracellular organelles in cystic fibrosis
    • Barasch, J., Kiss, B., Prince, A., Saiman, L., Gruenert, D., and al-Awqati, Q. (1991). Defective acidification of intracellular organelles in cystic fibrosis. Nature 352, 70-73.
    • (1991) Nature , vol.352 , pp. 70-73
    • Barasch, J.1    Kiss, B.2    Prince, A.3    Saiman, L.4    Gruenert, D.5    al-Awqati, Q.6
  • 2
    • 58749104212 scopus 로고    scopus 로고
    • Analysis of endocytic trafficking by single-cell fluorescence ratio imaging. Curr. Protoc. Cell Biol. Chapter
    • Unit 15 13
    • Barriere, H., and Lukacs, G. L. (2008). Analysis of endocytic trafficking by single-cell fluorescence ratio imaging. Curr. Protoc. Cell Biol. Chapter 15, Unit 15 13.
    • (2008) , vol.15
    • Barriere, H.1    Lukacs, G.L.2
  • 3
    • 34948905713 scopus 로고    scopus 로고
    • Plasticity of polyubiquitin recognition as lysosomal targeting signals by the endosomal sorting machinery
    • Barriere, H., Nemes, C., Du, K., and Lukacs, G. L. (2007). Plasticity of polyubiquitin recognition as lysosomal targeting signals by the endosomal sorting machinery. Mol. Biol. Cell 18, 3952-3965.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 3952-3965
    • Barriere, H.1    Nemes, C.2    Du, K.3    Lukacs, G.L.4
  • 4
    • 33644529627 scopus 로고    scopus 로고
    • Molecular basis of oligoubiquitin-dependent internalization of membrane proteins in mammalian cells
    • Barriere, H., Nemes, C., Lechardeur, D., Khan-Mohammad, M., Fruh, K., and Lukacs, G. L. (2006). Molecular basis of oligoubiquitin-dependent internalization of membrane proteins in mammalian cells. Traffic 7, 282-297.
    • (2006) Traffic , vol.7 , pp. 282-297
    • Barriere, H.1    Nemes, C.2    Lechardeur, D.3    Khan-Mohammad, M.4    Fruh, K.5    Lukacs, G.L.6
  • 5
    • 29244446796 scopus 로고    scopus 로고
    • Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers
    • Bebok, Z., Collawn, J. F., Wakefield, J., Parker, W., Li, Y., Varga, K., Sorscher, E. J., and Clancy, J. P. (2005). Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers. J. Physiol. 569, 601-615.
    • (2005) J. Physiol , vol.569 , pp. 601-615
    • Bebok, Z.1    Collawn, J.F.2    Wakefield, J.3    Parker, W.4    Li, Y.5    Varga, K.6    Sorscher, E.J.7    Clancy, J.P.8
  • 7
    • 0035947777 scopus 로고    scopus 로고
    • COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments
    • Benharouga, M., Haardt, M., Kartner, N., and Lukacs, G. L. (2001). COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments. J. Cell Biol. 153, 957-970.
    • (2001) J. Cell Biol , vol.153 , pp. 957-970
    • Benharouga, M.1    Haardt, M.2    Kartner, N.3    Lukacs, G.L.4
  • 8
    • 0038158316 scopus 로고    scopus 로고
    • The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia
    • Benharouga, M., Sharma, M., So, J., Haardt, M., Drzymala, L., Popov, M., Schwapach, B., Grinstein, S., Du, K., and Lukacs, G. L. (2003). The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia. J. Biol. Chem. 278, 22079-22089.
    • (2003) J. Biol. Chem , vol.278 , pp. 22079-22089
    • Benharouga, M.1    Sharma, M.2    So, J.3    Haardt, M.4    Drzymala, L.5    Popov, M.6    Schwapach, B.7    Grinstein, S.8    Du, K.9    Lukacs, G.L.10
  • 9
    • 0028045712 scopus 로고
    • Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells
    • Biwersi, J., and Verkman, A. S. (1994). Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells. Am J. Physiol. 266, C149-C156.
    • (1994) Am J. Physiol , vol.266
    • Biwersi, J.1    Verkman, A.S.2
  • 10
    • 33947725805 scopus 로고    scopus 로고
    • G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defects
    • Bompadre, S. G., Sohma, Y., Li, M., and Hwang, T. C. (2007). G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defects. J. Gen. Physiol. 129, 285-298.
    • (2007) J. Gen. Physiol , vol.129 , pp. 285-298
    • Bompadre, S.G.1    Sohma, Y.2    Li, M.3    Hwang, T.C.4
  • 12
    • 34249662628 scopus 로고    scopus 로고
    • Cystic fibrosis: A disease of vulnerability to airway surface dehydration
    • Boucher, R. C. (2007). Cystic fibrosis: a disease of vulnerability to airway surface dehydration. Trends Mol. Med. 13, 231-240.
    • (2007) Trends Mol. Med , vol.13 , pp. 231-240
    • Boucher, R.C.1
  • 13
    • 0036272055 scopus 로고    scopus 로고
    • Isolation of CF cell lines corrected at DeltaF508-CFTR locus by SFHR-mediated targeting
    • Bruscia, E., Sangiuolo, F., Sinibaldi, P., Goncz, K. K., Novelli, G., and Gruenert, D. C. (2002). Isolation of CF cell lines corrected at DeltaF508-CFTR locus by SFHR-mediated targeting. Gene Ther. 9, 683-685.
    • (2002) Gene Ther , vol.9 , pp. 683-685
    • Bruscia, E.1    Sangiuolo, F.2    Sinibaldi, P.3    Goncz, K.K.4    Novelli, G.5    Gruenert, D.C.6
  • 15
    • 40649112565 scopus 로고    scopus 로고
    • Airway epithelial control of Pseudomonas aeruginosa infection in cystic fibrosis
    • Campodonico, V. L., Gadjeva, M., Paradis-Bleau, C., Uluer, A., and Pier, G. B. (2008). Airway epithelial control of Pseudomonas aeruginosa infection in cystic fibrosis. Trends Mol. Med. 14, 120-133.
    • (2008) Trends Mol. Med , vol.14 , pp. 120-133
    • Campodonico, V.L.1    Gadjeva, M.2    Paradis-Bleau, C.3    Uluer, A.4    Pier, G.B.5
  • 16
    • 0034830361 scopus 로고    scopus 로고
    • Proton leak and CFTR in regulation of Golgi pH in respiratory epithelial cells
    • Chandy, G., Grabe, M., Moore, H. P., and Machen, T. E. (2001). Proton leak and CFTR in regulation of Golgi pH in respiratory epithelial cells. Am J. Physiol. Cell Physiol. 281, C908-C921.
    • (2001) Am J. Physiol. Cell Physiol , vol.281
    • Chandy, G.1    Grabe, M.2    Moore, H.P.3    Machen, T.E.4
  • 17
    • 84934434216 scopus 로고    scopus 로고
    • EM analysis of phagosomes
    • Chastellier, C. D. (2008). EM analysis of phagosomes. Methods Mol. Biol. 445, 261-285.
    • (2008) Methods Mol. Biol , vol.445 , pp. 261-285
    • Chastellier, C.D.1
  • 19
    • 33748146503 scopus 로고    scopus 로고
    • CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
    • Di, A., et al. (2006). CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nat. Cell Biol. 8, 933-944.
    • (2006) Nat. Cell Biol , vol.8 , pp. 933-944
    • Di, A.1
  • 20
    • 54049156405 scopus 로고    scopus 로고
    • The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel
    • Dong, X. P., Cheng, X., Mills, E., Delling, M., Wang, F., Kurz, T., and Xu, H. (2008). The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel. Nature 455, 992-996.
    • (2008) Nature , vol.455 , pp. 992-996
    • Dong, X.P.1    Cheng, X.2    Mills, E.3    Delling, M.4    Wang, F.5    Kurz, T.6    Xu, H.7
  • 21
    • 56049103965 scopus 로고    scopus 로고
    • Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: Mutations in MLC1 cause folding defects
    • Duarri, A., et al. (2008). Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: mutations in MLC1 cause folding defects. Hum Mol. Genet 17, 3728-3739.
    • (2008) Hum Mol. Genet , vol.17 , pp. 3728-3739
    • Duarri, A.1
  • 22
    • 0028111942 scopus 로고
    • Regulation of endocytic trafficking and acidification are independent of the cystic fibrosis transmembrane regulator
    • Dunn, K. W., Park, J., Semrad, C. E., Gelman, D. L., Shevell, T., and McGraw, T. E. (1994). Regulation of endocytic trafficking and acidification are independent of the cystic fibrosis transmembrane regulator. J. Biol. Chem. 269, 5336-5345.
    • (1994) J. Biol. Chem , vol.269 , pp. 5336-5345
    • Dunn, K.W.1    Park, J.2    Semrad, C.E.3    Gelman, D.L.4    Shevell, T.5    McGraw, T.E.6
  • 23
    • 0032407699 scopus 로고    scopus 로고
    • Structure, function and regulation of the vacuolar (H+)-ATPases
    • Forgac, M. (1998). Structure, function and regulation of the vacuolar (H+)-ATPases. FEBS Lett. 440, 258-263.
    • (1998) FEBS Lett , vol.440 , pp. 258-263
    • Forgac, M.1
  • 24
    • 0019513926 scopus 로고
    • Temporal changes of lysosome and phagosome pH during phagolysosome formation in macrophages: Studies by fluorescence spectroscopy
    • Geisow, M. J., D'Arcy Hart, P., and Young, M. R. (1981). Temporal changes of lysosome and phagosome pH during phagolysosome formation in macrophages: studies by fluorescence spectroscopy. J. Cell Biol. 89, 645-652.
    • (1981) J. Cell Biol , vol.89 , pp. 645-652
    • Geisow, M.J.1    D'Arcy Hart, P.2    Young, M.R.3
  • 25
    • 33847357783 scopus 로고    scopus 로고
    • Misassembled mutant DeltaF508 CFTR in the distal secretory pathway alters cellular lipid trafficking
    • Gentzsch, M., Choudhury, A., Chang, X. B., Pagano, R. E., and Riordan, J. R. (2007). Misassembled mutant DeltaF508 CFTR in the distal secretory pathway alters cellular lipid trafficking. J. Cell Sci. 120, 447-455.
    • (2007) J. Cell Sci , vol.120 , pp. 447-455
    • Gentzsch, M.1    Choudhury, A.2    Chang, X.B.3    Pagano, R.E.4    Riordan, J.R.5
  • 26
    • 0033696130 scopus 로고    scopus 로고
    • Evidence against the acidification hypothesis in cystic fibrosis
    • Gibson, G. A., Hill, W. G., and Weisz, O. A. (2000). Evidence against the acidification hypothesis in cystic fibrosis. Am J. Physiol. Cell Physiol. 279, C1088-C1099.
    • (2000) Am J. Physiol. Cell Physiol , vol.279
    • Gibson, G.A.1    Hill, W.G.2    Weisz, O.A.3
  • 27
    • 64049096002 scopus 로고    scopus 로고
    • N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic
    • Glozman, R., Okiyoneda, T., Mulvihill, C. M., Rini, J. M., Barriere, H., and Lukacs, G. L. (2009). N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic. J. Cell Biol. 184, 847-862.
    • (2009) J. Cell Biol , vol.184 , pp. 847-862
    • Glozman, R.1    Okiyoneda, T.2    Mulvihill, C.M.3    Rini, J.M.4    Barriere, H.5    Lukacs, G.L.6
  • 28
    • 0035024033 scopus 로고    scopus 로고
    • Regulation of organelle acidity
    • Grabe, M., and Oster, G. (2001). Regulation of organelle acidity. J. Gen Physiol. 117, 329-344.
    • (2001) J. Gen Physiol , vol.117 , pp. 329-344
    • Grabe, M.1    Oster, G.2
  • 29
    • 44849107047 scopus 로고    scopus 로고
    • The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes
    • Graves, A. R., Curran, P. K., Smith, C. L., and Mindell, J. A. (2008). The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes. Nature 453, 788-792.
    • (2008) Nature , vol.453 , pp. 788-792
    • Graves, A.R.1    Curran, P.K.2    Smith, C.L.3    Mindell, J.A.4
  • 30
    • 0024787848 scopus 로고
    • A quantitative analysis of the endocytic pathway in baby hamster kidney cells
    • Griffiths, G., Back, R., and Marsh, M. (1989). A quantitative analysis of the endocytic pathway in baby hamster kidney cells. J. Cell Biol. 109, 2703-2720.
    • (1989) J. Cell Biol , vol.109 , pp. 2703-2720
    • Griffiths, G.1    Back, R.2    Marsh, M.3
  • 31
    • 0028933682 scopus 로고
    • Culture and transformation of human airway epithelial cells
    • Gruenert, D. C., Finkbeiner, W. E., and Widdicombe, J. H. (1995). Culture and transformation of human airway epithelial cells. Am J. Physiol. 268, L347-L360.
    • (1995) Am J. Physiol , vol.268
    • Gruenert, D.C.1    Finkbeiner, W.E.2    Widdicombe, J.H.3
  • 32
    • 37549012987 scopus 로고    scopus 로고
    • Fenretinide corrects newly found ceramide deficiency in cystic fibrosis
    • Guilbault, C., et al. (2008). Fenretinide corrects newly found ceramide deficiency in cystic fibrosis. Am J. Respir Cell. Mol. Biol. 38, 47-56.
    • (2008) Am J. Respir Cell. Mol. Biol , vol.38 , pp. 47-56
    • Guilbault, C.1
  • 33
    • 0032493276 scopus 로고    scopus 로고
    • ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells
    • Gunther, W., Luchow, A., Cluzeaud, F., Vandewalle, A., and Jentsch, T. J. (1998). ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells. Proc. Natl. Acad. Sci. USA 95, 8075-8080.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8075-8080
    • Gunther, W.1    Luchow, A.2    Cluzeaud, F.3    Vandewalle, A.4    Jentsch, T.J.5
  • 34
    • 0030662045 scopus 로고    scopus 로고
    • Regulation of phagosomal acidification. Differential targeting of Na+/H+ exchangers, Na+/K+-ATPases, and vacuolar-type H+-ATPases
    • Hackam, D. J., Rotstein, O. D., Zhang, W. J., Demaurex, N., Woodside, M., Tsai, O., and Grinstein, S. (1997). Regulation of phagosomal acidification. Differential targeting of Na+/H+ exchangers, Na+/K+-ATPases, and vacuolar-type H+-ATPases. J. Biol. Chem. 272, 29810-29820.
    • (1997) J. Biol. Chem , vol.272 , pp. 29810-29820
    • Hackam, D.J.1    Rotstein, O.D.2    Zhang, W.J.3    Demaurex, N.4    Woodside, M.5    Tsai, O.6    Grinstein, S.7
  • 35
    • 35748973573 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages
    • Haggie, P. M., and Verkman, A. S. (2007). Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages. J. Biol. Chem. 282, 31422-31428.
    • (2007) J. Biol. Chem , vol.282 , pp. 31422-31428
    • Haggie, P.M.1    Verkman, A.S.2
  • 36
    • 67049172475 scopus 로고    scopus 로고
    • Defective Organellar Acidification as a Cause of Cystic Fibrosis Lung Disease - Re-Examination of a Recurring Hypothesis
    • Haggie, P. M., and Verkman, A. S. (2009a). Defective Organellar Acidification as a Cause of Cystic Fibrosis Lung Disease - Re-Examination of a Recurring Hypothesis. Am J. Physiol. Lung Cell Mol. Physiol. 296, L859-L867.
    • (2009) Am J. Physiol. Lung Cell Mol. Physiol , vol.296
    • Haggie, P.M.1    Verkman, A.S.2
  • 37
    • 65549134742 scopus 로고    scopus 로고
    • Unimpaired lysosomal acidification in respiratory epithelial cells in cystic fibrosis
    • Haggie, P. M., and Verkman, A. S. (2009b). Unimpaired lysosomal acidification in respiratory epithelial cells in cystic fibrosis. J. Biol. Chem. 284, 7681-7686.
    • (2009) J. Biol. Chem , vol.284 , pp. 7681-7686
    • Haggie, P.M.1    Verkman, A.S.2
  • 39
    • 12544249991 scopus 로고    scopus 로고
    • ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation
    • Hara-Chikuma, M., Yang, B., Sonawane, N. D., Sasaki, S., Uchida, S., and Verkman, A. S. (2005b). ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation. J. Biol. Chem. 280, 1241-1247.
    • (2005) J. Biol. Chem , vol.280 , pp. 1241-1247
    • Hara-Chikuma, M.1    Yang, B.2    Sonawane, N.D.3    Sasaki, S.4    Uchida, S.5    Verkman, A.S.6
  • 40
    • 0023578990 scopus 로고
    • Inhibition of phagosome-lysosome fusion in macrophages by certain mycobacteria can be explained by inhibition of lysosomal movements observed after phagocytosis
    • Hart, P. D., Young, M. R., Gordon, A. H., and Sullivan, K. H. (1987). Inhibition of phagosome-lysosome fusion in macrophages by certain mycobacteria can be explained by inhibition of lysosomal movements observed after phagocytosis. J. Exp. Med. 166, 933-946.
    • (1987) J. Exp. Med , vol.166 , pp. 933-946
    • Hart, P.D.1    Young, M.R.2    Gordon, A.H.3    Sullivan, K.H.4
  • 41
    • 0035013543 scopus 로고    scopus 로고
    • The ΔF508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells
    • Heda, G., Tanwani, M., and Marino, C. (2001). The ΔF508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells. Am J. Physiol. Cell Physiol. 49, C166-C174.
    • (2001) Am J. Physiol. Cell Physiol , vol.49
    • Heda, G.1    Tanwani, M.2    Marino, C.3
  • 42
    • 33645152194 scopus 로고    scopus 로고
    • V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway
    • Hurtado-Lorenzo, A., et al. (2006). V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat. Cell Biol. 8, 124-136.
    • (2006) Nat. Cell Biol , vol.8 , pp. 124-136
    • Hurtado-Lorenzo, A.1
  • 43
    • 46049100082 scopus 로고    scopus 로고
    • Function, structure and regulation of the vacuolar (H+)-ATPases
    • Jefferies, K. C., Cipriano, D. J., and Forgac, M. (2008). Function, structure and regulation of the vacuolar (H+)-ATPases. Arch. Biochem. Biophys. 476, 33- 42.
    • (2008) Arch. Biochem. Biophys , vol.476 , pp. 33-42
    • Jefferies, K.C.1    Cipriano, D.J.2    Forgac, M.3
  • 44
    • 33846517681 scopus 로고    scopus 로고
    • Chloride and the endosomal-lysosomal pathway: Emerging roles of CLC chloride transporters
    • Jentsch, T. J. (2007). Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters. J. Physiol. 578, 633-640.
    • (2007) J. Physiol , vol.578 , pp. 633-640
    • Jentsch, T.J.1
  • 45
    • 15544362767 scopus 로고    scopus 로고
    • Physiological functions of CLC Cl- channels gleaned from human genetic disease and mouse models
    • Jentsch, T. J., Poet, M., Fuhrmann, J. C., and Zdebik, A. A. (2005). Physiological functions of CLC Cl- channels gleaned from human genetic disease and mouse models. Annu. Rev. Physiol. 67, 779-807.
    • (2005) Annu. Rev. Physiol , vol.67 , pp. 779-807
    • Jentsch, T.J.1    Poet, M.2    Fuhrmann, J.C.3    Zdebik, A.A.4
  • 47
    • 0028015883 scopus 로고
    • Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation
    • Konstan, M. W., Hilliard, K. A., Norvell, T. M., and Berger, M. (1994). Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation. Am J. Respir. Crit. Care Med. 150, 448-454.
    • (1994) Am J. Respir. Crit. Care Med , vol.150 , pp. 448-454
    • Konstan, M.W.1    Hilliard, K.A.2    Norvell, T.M.3    Berger, M.4
  • 48
    • 36849091453 scopus 로고    scopus 로고
    • Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis
    • Kumar, K. G., et al. (2007). Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. J. Cell Biol. 179, 935-950.
    • (2007) J. Cell Biol , vol.179 , pp. 935-950
    • Kumar, K.G.1
  • 49
    • 58949097885 scopus 로고    scopus 로고
    • Burkholderia cenocepacia-induced delay of acidification and phagolysosomal fusion in cystic fibrosis transmembrane conductance regulator (CFTR)-defective macrophages
    • Lamothe, J., and Valvano, M. A. (2008). Burkholderia cenocepacia-induced delay of acidification and phagolysosomal fusion in cystic fibrosis transmembrane conductance regulator (CFTR)-defective macrophages. Microbiology 154, 3825-3834.
    • (2008) Microbiology , vol.154 , pp. 3825-3834
    • Lamothe, J.1    Valvano, M.A.2
  • 50
    • 10344262595 scopus 로고    scopus 로고
    • Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells
    • Lechardeur, D., Xu, M., and Lukacs, G. L. (2004). Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells. J. Cell Biol. 167, 851-862.
    • (2004) J. Cell Biol , vol.167 , pp. 851-862
    • Lechardeur, D.1    Xu, M.2    Lukacs, G.L.3
  • 51
    • 0036086313 scopus 로고    scopus 로고
    • The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells
    • Li, X., Wang, T., Zhao, Z., and Weinman, S. A. (2002). The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells. Am J. Physiol. Cell Physiol. 282, C1483-C1491.
    • (2002) Am J. Physiol. Cell Physiol , vol.282
    • Li, X.1    Wang, T.2    Zhao, Z.3    Weinman, S.A.4
  • 52
    • 0032499784 scopus 로고    scopus 로고
    • Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
    • Llopis, J., McCaffery, J. M., Miyawaki, A., Farquhar, M. G., and Tsien, R. Y. (1998). Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins. Proc. Natl. Acad. Sci. USA 95, 6803-6808.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6803-6808
    • Llopis, J.1    McCaffery, J.M.2    Miyawaki, A.3    Farquhar, M.G.4    Tsien, R.Y.5
  • 53
    • 0026777811 scopus 로고
    • The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH
    • Lukacs, G. L., Chang, X. B., Kartner, N., Rotstein, O. D., Riordan, J. R., and Grinstein, S. (1992). The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH. J. Biol. Chem. 267, 14568-14572.
    • (1992) J. Biol. Chem , vol.267 , pp. 14568-14572
    • Lukacs, G.L.1    Chang, X.B.2    Kartner, N.3    Rotstein, O.D.4    Riordan, J.R.5    Grinstein, S.6
  • 54
    • 0025614488 scopus 로고
    • Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages
    • Lukacs, G. L., Rotstein, O. D., and Grinstein, S. (1990). Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages. J. Biol. Chem. 265, 21099-21107.
    • (1990) J. Biol. Chem , vol.265 , pp. 21099-21107
    • Lukacs, G.L.1    Rotstein, O.D.2    Grinstein, S.3
  • 55
    • 0026348650 scopus 로고    scopus 로고
    • Lukacs, G. L., Rotstein, O. D., and Grinstein, S. (1991). Determinants of the phagosomal pH in macrophages. In situ assessment of vacuolar H(+)-ATPase activity, counterion conductance, and H+ leak. J. Biol. Chem. 266, 24540-24548.
    • Lukacs, G. L., Rotstein, O. D., and Grinstein, S. (1991). Determinants of the phagosomal pH in macrophages. In situ assessment of vacuolar H(+)-ATPase activity, counterion conductance, and H+ "leak." J. Biol. Chem. 266, 24540-24548.
  • 56
    • 0035411564 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator and H+ permeability in regulation of Golgi pH
    • Machen, T. E., Chandy, G., Wu, M., Grabe, M., and Moore, H. P. (2001). Cystic fibrosis transmembrane conductance regulator and H+ permeability in regulation of Golgi pH. J. Pancreas 2, 229-236.
    • (2001) J. Pancreas , vol.2 , pp. 229-236
    • Machen, T.E.1    Chandy, G.2    Wu, M.3    Grabe, M.4    Moore, H.P.5
  • 57
    • 0038339673 scopus 로고    scopus 로고
    • pH of TGN and recycling endosomes of H+/K+-ATPase- transfected HEK-293 cells: Implications for pH regulation in the secretory pathway
    • Machen, T. E., Leigh, M. J., Taylor, C., Kimura, T., Asano, S., and Moore, H. P. (2003). pH of TGN and recycling endosomes of H+/K+-ATPase- transfected HEK-293 cells: implications for pH regulation in the secretory pathway. Am J. Physiol. Cell Physiol. 285, C205-C214.
    • (2003) Am J. Physiol. Cell Physiol , vol.285
    • Machen, T.E.1    Leigh, M.J.2    Taylor, C.3    Kimura, T.4    Asano, S.5    Moore, H.P.6
  • 58
    • 54849412682 scopus 로고    scopus 로고
    • Role of the vesicular chloride transporter ClC-3 in neuroendocrine tissue
    • Maritzen, T., Keating, D. J., Neagoe, I., Zdebik, A. A., and Jentsch, T. J. (2008). Role of the vesicular chloride transporter ClC-3 in neuroendocrine tissue. J. Neurosci. 28, 10587-10598.
    • (2008) J. Neurosci , vol.28 , pp. 10587-10598
    • Maritzen, T.1    Keating, D.J.2    Neagoe, I.3    Zdebik, A.A.4    Jentsch, T.J.5
  • 59
    • 0036736777 scopus 로고    scopus 로고
    • Physiological importance of endosomal acidification: Potential role in proximal tubulopathies
    • Marshansky, V., Ausiello, D. A., and Brown, D. (2002). Physiological importance of endosomal acidification: potential role in proximal tubulopathies. Curr. Opin. Nephrol. Hypertens. 11, 527-537.
    • (2002) Curr. Opin. Nephrol. Hypertens , vol.11 , pp. 527-537
    • Marshansky, V.1    Ausiello, D.A.2    Brown, D.3
  • 60
    • 47349120492 scopus 로고    scopus 로고
    • The V-type H+-ATPase in vesicular trafficking: Targeting, regulation and function
    • Marshansky, V., and Futai, M. (2008). The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function. Curr. Opin. Cell Biol. 20, 415-426.
    • (2008) Curr. Opin. Cell Biol , vol.20 , pp. 415-426
    • Marshansky, V.1    Futai, M.2
  • 61
    • 0022555867 scopus 로고
    • Acidification of the endocytic and exocytic pathways
    • Mellman, I., Fuchs, R., and Helenius, A. (1986). Acidification of the endocytic and exocytic pathways. Annu. Rev. Biochem. 55, 663-700.
    • (1986) Annu. Rev. Biochem , vol.55 , pp. 663-700
    • Mellman, I.1    Fuchs, R.2    Helenius, A.3
  • 62
    • 0344390884 scopus 로고    scopus 로고
    • A PDZ-interacting domain in CFTR is an apical membrane polarization signal
    • Moyer, B. D., et al. (1999). A PDZ-interacting domain in CFTR is an apical membrane polarization signal. J. Clin. Invest. 104, 1353-1361.
    • (1999) J. Clin. Invest , vol.104 , pp. 1353-1361
    • Moyer, B.D.1
  • 63
    • 3843066593 scopus 로고    scopus 로고
    • Discovery of glycine hydrazide pore-occluding CFTR inhibitors: Mechanism, structure-activity analysis, and in vivo efficacy
    • Muanprasat, C., Sonawane, N. D., Salinas, D., Taddei, A., Galietta, L. J., and Verkman, A. S. (2004). Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J. Gen Physiol. 124, 125-137.
    • (2004) J. Gen Physiol , vol.124 , pp. 125-137
    • Muanprasat, C.1    Sonawane, N.D.2    Salinas, D.3    Taddei, A.4    Galietta, L.J.5    Verkman, A.S.6
  • 65
    • 44349171796 scopus 로고    scopus 로고
    • Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor
    • Olson, L. J., Hindsgaul, O., Dahms, N. M., and Kim, J. J. (2008). Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor. J. Biol. Chem. 283, 10124-10134.
    • (2008) J. Biol. Chem , vol.283 , pp. 10124-10134
    • Olson, L.J.1    Hindsgaul, O.2    Dahms, N.M.3    Kim, J.J.4
  • 66
    • 34547963769 scopus 로고    scopus 로고
    • Emerging roles of alkali cation/proton exchangers in organellar homeostasis
    • Orlowski, J., and Grinstein, S. (2007). Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Curr. Opin. Cell Biol. 19, 483-492.
    • (2007) Curr. Opin. Cell Biol , vol.19 , pp. 483-492
    • Orlowski, J.1    Grinstein, S.2
  • 67
    • 24644464284 scopus 로고    scopus 로고
    • Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening
    • Pedemonte, N., Lukacs, G. L., Du, K., Caci, E., Zegarra-Moran, O., Galietta, L. J., and Verkman, A. S. (2005). Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. J. Clin. Invest. 115, 2564-2571.
    • (2005) J. Clin. Invest , vol.115 , pp. 2564-2571
    • Pedemonte, N.1    Lukacs, G.L.2    Du, K.3    Caci, E.4    Zegarra-Moran, O.5    Galietta, L.J.6    Verkman, A.S.7
  • 68
    • 22944475536 scopus 로고    scopus 로고
    • Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5
    • Picollo, A., and Pusch, M. (2005). Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5. Nature 436, 420-423.
    • (2005) Nature , vol.436 , pp. 420-423
    • Picollo, A.1    Pusch, M.2
  • 69
    • 0029961331 scopus 로고    scopus 로고
    • How mutant CFTR may contribute to Pseudomonas aeruginosa infection in cystic fibrosis
    • Pier, G. B., Grout, M., Zaidi, T. S., and Goldberg, J. B. (1996). How mutant CFTR may contribute to Pseudomonas aeruginosa infection in cystic fibrosis. Am J. Respir. Crit. Care Med. 154, S175-S182.
    • (1996) Am J. Respir. Crit. Care Med , vol.154
    • Pier, G.B.1    Grout, M.2    Zaidi, T.S.3    Goldberg, J.B.4
  • 71
    • 33745196486 scopus 로고    scopus 로고
    • Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade
    • Poschet, J. F., Fazio, J. A., Timmins, G. S., Ornatowski, W., Perkett, E., Delgado, M., and Deretic, V. (2006). Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade. EMBO Rep. 7, 553-559.
    • (2006) EMBO Rep , vol.7 , pp. 553-559
    • Poschet, J.F.1    Fazio, J.A.2    Timmins, G.S.3    Ornatowski, W.4    Perkett, E.5    Delgado, M.6    Deretic, V.7
  • 72
    • 0037134419 scopus 로고    scopus 로고
    • Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells
    • Poschet, J. F., Skidmore, J., Boucher, J. C., Firoved, A. M., Van Dyke, R. W., and Deretic, V. (2002). Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells. J. Biol. Chem. 277, 13959-13965.
    • (2002) J. Biol. Chem , vol.277 , pp. 13959-13965
    • Poschet, J.F.1    Skidmore, J.2    Boucher, J.C.3    Firoved, A.M.4    Van Dyke, R.W.5    Deretic, V.6
  • 73
    • 50649123290 scopus 로고    scopus 로고
    • CFTR function and prospects for therapy
    • Riordan, J. R. (2008). CFTR function and prospects for therapy. Annu. Rev. Biochem. 77, 701-726.
    • (2008) Annu. Rev. Biochem , vol.77 , pp. 701-726
    • Riordan, J.R.1
  • 74
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
    • Riordan, J. R., et al. (1989). Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245, 1066-1073.
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1
  • 75
    • 0019554835 scopus 로고
    • Intracellular pH
    • Roos, A., and Boron, W. F. (1981). Intracellular pH. Physiol. Rev. 61, 296-434.
    • (1981) Physiol. Rev , vol.61 , pp. 296-434
    • Roos, A.1    Boron, W.F.2
  • 78
    • 34548282581 scopus 로고    scopus 로고
    • Sputum biomarkers of inflammation in cystic fibrosis lung disease
    • Sagel, S. D., Chmiel, J. F., and Konstan, M. W. (2007). Sputum biomarkers of inflammation in cystic fibrosis lung disease. Proc. Am Thorac. Soc. 4, 406-417.
    • (2007) Proc. Am Thorac. Soc , vol.4 , pp. 406-417
    • Sagel, S.D.1    Chmiel, J.F.2    Konstan, M.W.3
  • 79
    • 34848916433 scopus 로고    scopus 로고
    • Luminal chloride-dependent activation of endosome calcium channels: Patch clamp study of enlarged endosomes
    • Saito, M., Hanson, P. I., and Schlesinger, P. (2007). Luminal chloride-dependent activation of endosome calcium channels: patch clamp study of enlarged endosomes. J. Biol. Chem. 282, 27327-27333.
    • (2007) J. Biol. Chem , vol.282 , pp. 27327-27333
    • Saito, M.1    Hanson, P.I.2    Schlesinger, P.3
  • 80
    • 22944479662 scopus 로고    scopus 로고
    • Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins
    • Scheel, O., Zdebik, A. A., Lourdel, S., and Jentsch, T. J. (2005). Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins. Nature 436, 424-427.
    • (2005) Nature , vol.436 , pp. 424-427
    • Scheel, O.1    Zdebik, A.A.2    Lourdel, S.3    Jentsch, T.J.4
  • 81
    • 58849125253 scopus 로고    scopus 로고
    • A chloride conductance in VGLUT1 underlies maximal glutamate loading into synaptic vesicles
    • Schenck, S., Wojcik, S. M., Brose, N., and Takamori, S. (2009). A chloride conductance in VGLUT1 underlies maximal glutamate loading into synaptic vesicles. Nat. Neurosci. 12, 156-162.
    • (2009) Nat. Neurosci , vol.12 , pp. 156-162
    • Schenck, S.1    Wojcik, S.M.2    Brose, N.3    Takamori, S.4
  • 82
    • 0029984180 scopus 로고    scopus 로고
    • Evidence against defective trans-Golgi acidification in cystic fibrosis
    • Seksek, O., Biwersi, J., and Verkman, A. S. (1996). Evidence against defective trans-Golgi acidification in cystic fibrosis. J. Biol. Chem. 271, 15542-15548.
    • (1996) J. Biol. Chem , vol.271 , pp. 15542-15548
    • Seksek, O.1    Biwersi, J.2    Verkman, A.S.3
  • 83
    • 0035937847 scopus 로고    scopus 로고
    • Conformational and temperature-sensitive stability defects of the delta F508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments
    • Sharma, M., Benharouga, M., Hu, W., and Lukacs, G. L. (2001). Conformational and temperature-sensitive stability defects of the delta F508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments. J. Biol. Chem. 276, 8942-8950.
    • (2001) J. Biol. Chem , vol.276 , pp. 8942-8950
    • Sharma, M.1    Benharouga, M.2    Hu, W.3    Lukacs, G.L.4
  • 84
    • 12144287602 scopus 로고    scopus 로고
    • Misfolding diverts CFTR from recycling to degradation: Quality control at early endosomes
    • Sharma, M., et al. (2004). Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes. J. Cell Biol. 164, 923-933.
    • (2004) J. Cell Biol , vol.164 , pp. 923-933
    • Sharma, M.1
  • 85
    • 0037417419 scopus 로고    scopus 로고
    • Determinants of [Cl-] in recycling and late endosomes and Golgi complex measured using fluorescent ligands
    • Sonawane, N. D., and Verkman, A. S. (2003). Determinants of [Cl-] in recycling and late endosomes and Golgi complex measured using fluorescent ligands. J. Cell Biol. 160, 1129-1138.
    • (2003) J. Cell Biol , vol.160 , pp. 1129-1138
    • Sonawane, N.D.1    Verkman, A.S.2
  • 86
    • 47049088617 scopus 로고    scopus 로고
    • Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides
    • Sonawane, N. D., Zhao, D., Zegarra-Moran, O., Galietta, L. J., and Verkman, A. S. (2008). Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides. Chem. Biol 15, 718-728.
    • (2008) Chem. Biol , vol.15 , pp. 718-728
    • Sonawane, N.D.1    Zhao, D.2    Zegarra-Moran, O.3    Galietta, L.J.4    Verkman, A.S.5
  • 87
    • 45549083364 scopus 로고    scopus 로고
    • Assessment of phagosome formation and maturation by fluorescence microscopy
    • Steinberg, B. E., and Grinstein, S. (2007). Assessment of phagosome formation and maturation by fluorescence microscopy. Methods Mol. Biol. 412, 289-300.
    • (2007) Methods Mol. Biol , vol.412 , pp. 289-300
    • Steinberg, B.E.1    Grinstein, S.2
  • 88
    • 36749083072 scopus 로고    scopus 로고
    • Phagosomal acidification: Measurement, manipulation and functional consequences
    • Steinberg, B. E., Huynh, K. K., and Grinstein, S. (2007a). Phagosomal acidification: measurement, manipulation and functional consequences. Biochem. Soc. Trans. 35, 1083-1087.
    • (2007) Biochem. Soc. Trans , vol.35 , pp. 1083-1087
    • Steinberg, B.E.1    Huynh, K.K.2    Grinstein, S.3
  • 89
    • 34547230720 scopus 로고    scopus 로고
    • In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force
    • Steinberg, B. E., Touret, N., Vargas-Caballero, M., and Grinstein, S. (2007b). In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force. Proc. Natl. Acad. Sci. USA 104, 9523-9528.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 9523-9528
    • Steinberg, B.E.1    Touret, N.2    Vargas-Caballero, M.3    Grinstein, S.4
  • 90
    • 17744375755 scopus 로고    scopus 로고
    • Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus
    • Stobrawa, S. M., et al. (2001). Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus. Neuron 29, 185-196.
    • (2001) Neuron , vol.29 , pp. 185-196
    • Stobrawa, S.M.1
  • 91
    • 31944449588 scopus 로고    scopus 로고
    • Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers
    • Suzuki, T., Rai, T., Hayama, A., Sohara, E., Suda, S., Itoh, T., Sasaki, S., and Uchida, S. (2006). Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers. J. Cell. Physiol. 206, 792-798.
    • (2006) J. Cell. Physiol , vol.206 , pp. 792-798
    • Suzuki, T.1    Rai, T.2    Hayama, A.3    Sohara, E.4    Suda, S.5    Itoh, T.6    Sasaki, S.7    Uchida, S.8
  • 92
    • 27744482654 scopus 로고    scopus 로고
    • The short apical membrane half-life of rescued ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of ΔF508-CFTR in polarized human airway epithelial cells
    • Swiatecka-Urban, A., et al. (2005). The short apical membrane half-life of rescued ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of ΔF508-CFTR in polarized human airway epithelial cells. J. Biol. Chem. 280, 36762-36772.
    • (2005) J. Biol. Chem , vol.280 , pp. 36762-36772
    • Swiatecka-Urban, A.1
  • 93
    • 41849092177 scopus 로고    scopus 로고
    • Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis
    • Teichgraber, V., et al. (2008). Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat. Med. 14, 382-391.
    • (2008) Nat. Med , vol.14 , pp. 382-391
    • Teichgraber, V.1
  • 94
    • 0035830835 scopus 로고    scopus 로고
    • Growth hormone receptor ubiquitination coincides with recruitment to clathrin-coated membrane domains
    • van Kerkhof, P., Sachse, M., Klumperman, J., and Strous, G. J. (2001). Growth hormone receptor ubiquitination coincides with recruitment to clathrin-coated membrane domains. J. Biol. Chem. 276, 3778-3784.
    • (2001) J. Biol. Chem , vol.276 , pp. 3778-3784
    • van Kerkhof, P.1    Sachse, M.2    Klumperman, J.3    Strous, G.J.4
  • 95
    • 41149113942 scopus 로고    scopus 로고
    • Enhanced cell-surface stability of rescued ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones
    • Varga, K., Goldstein, R. F., Jurkuvenaite, A., Chen, L., Matalon, S., Sorscher, E. J., Bebok, Z., and Collawn, J. F. (2008). Enhanced cell-surface stability of rescued ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones. Biochem. J. 410, 555-564.
    • (2008) Biochem. J , vol.410 , pp. 555-564
    • Varga, K.1    Goldstein, R.F.2    Jurkuvenaite, A.3    Chen, L.4    Matalon, S.5    Sorscher, E.J.6    Bebok, Z.7    Collawn, J.F.8
  • 96
    • 50249171794 scopus 로고    scopus 로고
    • Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway
    • Varghese, B., et al. (2008). Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway. Mol. Cell. Biol. 28, 5275-5287.
    • (2008) Mol. Cell. Biol , vol.28 , pp. 5275-5287
    • Varghese, B.1
  • 97
    • 0038731763 scopus 로고    scopus 로고
    • Acidification and protein traffic
    • Weisz, O. A. (2003a). Acidification and protein traffic. Int. Rev. Cytol. 226, 259-319.
    • (2003) Int. Rev. Cytol , vol.226 , pp. 259-319
    • Weisz, O.A.1
  • 98
    • 0038105847 scopus 로고    scopus 로고
    • Organelle acidification and disease
    • Weisz, O. A. (2003b). Organelle acidification and disease. Traffic 4, 57-64.
    • (2003) Traffic , vol.4 , pp. 57-64
    • Weisz, O.A.1
  • 99
    • 0035980029 scopus 로고    scopus 로고
    • Mechanisms of pH regulation in the regulated secretory pathway
    • Wu, M. M., Grabe, M., Adams, S., Tsien, R. Y., Moore, H. P., and Machen, T. E. (2001). Mechanisms of pH regulation in the regulated secretory pathway. J. Biol. Chem. 276, 33027-33035.
    • (2001) J. Biol. Chem , vol.276 , pp. 33027-33035
    • Wu, M.M.1    Grabe, M.2    Adams, S.3    Tsien, R.Y.4    Moore, H.P.5    Machen, T.E.6
  • 100
    • 17444415369 scopus 로고    scopus 로고
    • The kinetics of phagosome maturation as a function of phagosome/lysosome fusion and acquisition of hydrolytic activity
    • Yates, R. M., Hermetter, A., and Russell, D. G. (2005). The kinetics of phagosome maturation as a function of phagosome/lysosome fusion and acquisition of hydrolytic activity. Traffic 6, 413-420.
    • (2005) Traffic , vol.6 , pp. 413-420
    • Yates, R.M.1    Hermetter, A.2    Russell, D.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.