The short apical membrane half-life of rescued ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of ΔF508H-CFTR in polarized human airway epithelial cells

Journal of Biological Chemistry

Volumn 280, Issue 44, 2005, Pages 36762-36772

  Swiatecka Urban, Agnieszka ^a   Brown, Andrea ^a   Moreau Marquis, Sophie ^a   Renuka, Janhavi ^a   Coutermarsh, Bonita ^a   Barnaby, Roxanna ^a   Karlson, Katherine H ^a   Flotte, Terence R ^b   Fukuda, Mitsunori ^c   Langford, George M ^d   Stanton, Bruce A ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d Dartmouth College   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; CELLS; GENES; POLARIZATION; PROTEINS; THERMAL EFFECTS;

APICAL MEMBRANE; CELLULAR DEFECTS; CYSTIC FIBROSIS; MUTATION;

CELL MEMBRANES;

TRANSMEMBRANE CONDUCTANCE REGULATOR;

APICAL MEMBRANE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; TEMPERATURE;

ATP-BINDING CASSETTE TRANSPORTERS; CELL MEMBRANE; CELL POLARITY; CELLS, CULTURED; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOCYTOSIS; EPITHELIAL CELLS; HALF-LIFE; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MUTATION; NEOPLASM PROTEINS; PLASMIDS; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS; RESPIRATORY MUCOSA; RNA, SMALL INTERFERING;

EID: 27744482654     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M508944200     Document Type: Article

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