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Volumn 77, Issue 7, 2009, Pages 2773-2782

CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C6; COMPLEMENT FACTOR H; COMPLEMENT MEMBRANE ATTACK COMPLEX; PROTEIN CSPA; UNCLASSIFIED DRUG;

EID: 67650070597     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00318-09     Document Type: Article
Times cited : (68)

References (71)
  • 3
    • 0036784619 scopus 로고    scopus 로고
    • Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs
    • Alitalo, A., T. Meri, H. Lankinen, I. Seppala, P. Lahdenne, P. S. Hefty, D. R. Akins, and S. Meri. 2002. Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs. J. Immunol. 169:3847-3853.
    • (2002) J. Immunol , vol.169 , pp. 3847-3853
    • Alitalo, A.1    Meri, T.2    Lankinen, H.3    Seppala, I.4    Lahdenne, P.5    Hefty, P.S.6    Akins, D.R.7    Meri, S.8
  • 5
    • 0021671855 scopus 로고
    • Isolation and cultivation of Lyme disease spirochetes
    • Barbour, A. G. 1984. Isolation and cultivation of Lyme disease spirochetes. Yale J. Biol. Med. 57:521-525.
    • (1984) Yale J. Biol. Med , vol.57 , pp. 521-525
    • Barbour, A.G.1
  • 6
    • 0026784998 scopus 로고
    • Differences of two Borrelia burgdorferi strains in complement activation and serum resistance
    • Brade, V., I. Kleber, and G. Acker. 1992. Differences of two Borrelia burgdorferi strains in complement activation and serum resistance. Immunobiology 185:453-465.
    • (1992) Immunobiology , vol.185 , pp. 453-465
    • Brade, V.1    Kleber, I.2    Acker, G.3
  • 7
    • 0030418391 scopus 로고    scopus 로고
    • Heterogeneity in the complement-dependent bacteriolysis within the species of Borrelia burgdorferi
    • Breitner-Ruddock, S., R. Wurzner, J. Schulze, and V. Brade. 1997. Heterogeneity in the complement-dependent bacteriolysis within the species of Borrelia burgdorferi. Med. Microbiol. Immunol. 185:253-260.
    • (1997) Med. Microbiol. Immunol , vol.185 , pp. 253-260
    • Breitner-Ruddock, S.1    Wurzner, R.2    Schulze, J.3    Brade, V.4
  • 8
    • 0038104769 scopus 로고    scopus 로고
    • Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals
    • Brooks, C. S., P. S. Hefty, S. E. Jolliff, and D. R. Akins. 2003. Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect. Immun. 71:3371-3383.
    • (2003) Infect. Immun , vol.71 , pp. 3371-3383
    • Brooks, C.S.1    Hefty, P.S.2    Jolliff, S.E.3    Akins, D.R.4
  • 9
    • 29644440332 scopus 로고    scopus 로고
    • Identification of Borrelia burgdorferi outer surface proteins
    • Brooks, C. S., S. R. Vuppala, A. M. Jett, and D. R. Akins. 2006. Identification of Borrelia burgdorferi outer surface proteins. Infect. Immun. 74:296-304.
    • (2006) Infect. Immun , vol.74 , pp. 296-304
    • Brooks, C.S.1    Vuppala, S.R.2    Jett, A.M.3    Akins, D.R.4
  • 10
    • 23844518311 scopus 로고    scopus 로고
    • Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi
    • Brooks, C. S., S. R. Vuppala, A. M. Jett, A. Alitalo, S. Meri, and D. R. Akins. 2005. Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi. J. Immunol. 175:3299-3308.
    • (2005) J. Immunol , vol.175 , pp. 3299-3308
    • Brooks, C.S.1    Vuppala, S.R.2    Jett, A.M.3    Alitalo, A.4    Meri, S.5    Akins, D.R.6
  • 11
    • 34548478386 scopus 로고    scopus 로고
    • Coordinated expression of Borrelia burgdorferi complement regulator-acquiring surface proteins during the Lyme disease spirochete's mammal-tick infection cycle
    • Bykowski, T., M. E. Woodman, A. E. Cooley, C. A. Brissette, V. Brade, R. Wallich, P. Kraiczy, and B. Stevenson. 2007. Coordinated expression of Borrelia burgdorferi complement regulator-acquiring surface proteins during the Lyme disease spirochete's mammal-tick infection cycle. Infect. Immun. 75:4227-4236.
    • (2007) Infect. Immun , vol.75 , pp. 4227-4236
    • Bykowski, T.1    Woodman, M.E.2    Cooley, A.E.3    Brissette, C.A.4    Brade, V.5    Wallich, R.6    Kraiczy, P.7    Stevenson, B.8
  • 12
    • 2442645223 scopus 로고    scopus 로고
    • The essential nature of the ubiquitous 26-kilobase circular replicon of Borrelia burgdorferi
    • Byram, R., P. E. Stewart, and P. Rosa. 2004. The essential nature of the ubiquitous 26-kilobase circular replicon of Borrelia burgdorferi. J. Bacteriol. 186:3561-3569.
    • (2004) J. Bacteriol , vol.186 , pp. 3561-3569
    • Byram, R.1    Stewart, P.E.2    Rosa, P.3
  • 14
  • 18
    • 0036166738 scopus 로고    scopus 로고
    • Identification of loci critical for replication and compatibility of a Borrelia burgdorferi cp32 plasmid and use of a cp32-based shuttle vector for the expression of fluorescent reporters in the Lyme disease spirochaete
    • Eggers, C. H., M. J. Caimano, M. L. Clawson, W. G. Miller, D. S. Samuels, and J. D. Radolf. 2002. Identification of loci critical for replication and compatibility of a Borrelia burgdorferi cp32 plasmid and use of a cp32-based shuttle vector for the expression of fluorescent reporters in the Lyme disease spirochaete. Mol. Microbiol. 43:281-295.
    • (2002) Mol. Microbiol , vol.43 , pp. 281-295
    • Eggers, C.H.1    Caimano, M.J.2    Clawson, M.L.3    Miller, W.G.4    Samuels, D.S.5    Radolf, J.D.6
  • 19
    • 33645467256 scopus 로고    scopus 로고
    • Sigma factor selectivity in Borrelia burgdorferi: RpoS recognition of the ospE/ospF/elp promoters is dependent on the sequence of the -10 region
    • Eggers, C. H., M. J. Caimano, and J. D. Radolf. 2006. Sigma factor selectivity in Borrelia burgdorferi: RpoS recognition of the ospE/ospF/elp promoters is dependent on the sequence of the -10 region. Mol. Microbiol. 59:1859-875.
    • (2006) Mol. Microbiol , vol.59 , pp. 1859-1875
    • Eggers, C.H.1    Caimano, M.J.2    Radolf, J.D.3
  • 23
    • 0031470826 scopus 로고    scopus 로고
    • Fraser, C. M., S. Casjens, W. M. Huang, G. G. Sutton, R. Clayton, R. Lathigra, O. White, K. A. Ketchum, R. Dodson, E. K. Hickey, M. Gwinn, B. Dougherty, J.-F. Tomb, R. D. Fleischmann, D. Richardson, J. Peterson, A. R. Kerlavage, J. Quackenbush, S. Salzberg, M. Hanson, R. van Vugt, N. Palmer, M. D. Adams, J. Gocayne, J. Weidman, T. Utterback, L. Watthey, L. McDonald, P. Artiach, C. Bowman, S. Garland, C. Fujii, M. D. Cotton, K. Horst, K. Roberts, B. Hatch, H. O. Smith, and J. C. Venter. 1997. Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390:580-586.
    • Fraser, C. M., S. Casjens, W. M. Huang, G. G. Sutton, R. Clayton, R. Lathigra, O. White, K. A. Ketchum, R. Dodson, E. K. Hickey, M. Gwinn, B. Dougherty, J.-F. Tomb, R. D. Fleischmann, D. Richardson, J. Peterson, A. R. Kerlavage, J. Quackenbush, S. Salzberg, M. Hanson, R. van Vugt, N. Palmer, M. D. Adams, J. Gocayne, J. Weidman, T. Utterback, L. Watthey, L. McDonald, P. Artiach, C. Bowman, S. Garland, C. Fujii, M. D. Cotton, K. Horst, K. Roberts, B. Hatch, H. O. Smith, and J. C. Venter. 1997. Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390:580-586.
  • 25
    • 34250872420 scopus 로고    scopus 로고
    • Binding of human factor H-related protein 1 to serum-resistant Borrelia burgdorferi is mediated by borrelial complement regulator-acquiring surface proteins
    • Haupt, K., P. Kraiczy, R. Wallich, V. Brade, C. Skerka, and P. F. Zipfel. 2007. Binding of human factor H-related protein 1 to serum-resistant Borrelia burgdorferi is mediated by borrelial complement regulator-acquiring surface proteins. J. Infect. Dis. 196:124-133.
    • (2007) J. Infect. Dis , vol.196 , pp. 124-133
    • Haupt, K.1    Kraiczy, P.2    Wallich, R.3    Brade, V.4    Skerka, C.5    Zipfel, P.F.6
  • 26
    • 0036840122 scopus 로고    scopus 로고
    • OspE-related, OspF-related, and Elp lipoproteins are immunogenic in baboons experimentally infected with Borrelia burgdorferi and in human Lyme disease patients
    • Hefty, P. S., C. S. Brooks, A. M. Jett, G. L. White, S. K. Wikel, R. C. Kennedy, and D. R. Akins. 2002. OspE-related, OspF-related, and Elp lipoproteins are immunogenic in baboons experimentally infected with Borrelia burgdorferi and in human Lyme disease patients. J. Clin. Microbiol. 40:4256-4265.
    • (2002) J. Clin. Microbiol , vol.40 , pp. 4256-4265
    • Hefty, P.S.1    Brooks, C.S.2    Jett, A.M.3    White, G.L.4    Wikel, S.K.5    Kennedy, R.C.6    Akins, D.R.7
  • 27
    • 0036084295 scopus 로고    scopus 로고
    • Changes in temporal and spatial patterns of outer surface lipoprotein expression generate population heterogeneity and antigenic diversity in the Lyme disease spirochete, Borrelia burgdorferi
    • Hefty, P. S., S. E. Jolliff, M. J. Caimano, S. K. Wikel, and D. R. Akins. 2002. Changes in temporal and spatial patterns of outer surface lipoprotein expression generate population heterogeneity and antigenic diversity in the Lyme disease spirochete, Borrelia burgdorferi. Infect. Immun. 70:3468-3478.
    • (2002) Infect. Immun , vol.70 , pp. 3468-3478
    • Hefty, P.S.1    Jolliff, S.E.2    Caimano, M.J.3    Wikel, S.K.4    Akins, D.R.5
  • 28
    • 0035019732 scopus 로고    scopus 로고
    • Regulation of OspE-related, OspF-related, and Elp lipoproteins of Borrelia burgdorferi strain 297 by mammalian host-specific signals
    • Hefty, P. S., S. E. Jolliff, M. J. Caimano, S. K. Wikel, J. D. Radolf, and D. R. Akins. 2001. Regulation of OspE-related, OspF-related, and Elp lipoproteins of Borrelia burgdorferi strain 297 by mammalian host-specific signals. Infect. Immun. 69:3618-3627.
    • (2001) Infect. Immun , vol.69 , pp. 3618-3627
    • Hefty, P.S.1    Jolliff, S.E.2    Caimano, M.J.3    Wikel, S.K.4    Radolf, J.D.5    Akins, D.R.6
  • 31
    • 33644780179 scopus 로고    scopus 로고
    • Selective binding of Borrelia burgdorferi OspE paralogs to factor H and serum proteins from diverse animals: Possible expansion of the role of OspE in Lyme disease pathogenesis
    • Hovis, K. M., E. Tran, C. M. Sundy, E. Buckles, J. V. McDowell, and R. T. Marconi. 2006. Selective binding of Borrelia burgdorferi OspE paralogs to factor H and serum proteins from diverse animals: possible expansion of the role of OspE in Lyme disease pathogenesis. Infect. Immun. 74:1967-1972.
    • (2006) Infect. Immun , vol.74 , pp. 1967-1972
    • Hovis, K.M.1    Tran, E.2    Sundy, C.M.3    Buckles, E.4    McDowell, J.V.5    Marconi, R.T.6
  • 32
    • 0043066684 scopus 로고    scopus 로고
    • Complement resistance mechanisms of streptococci
    • Jarva, H., T. S. Jokiranta, R. Wurzner, and S. Meri. 2003. Complement resistance mechanisms of streptococci. Mol. Immunol. 40:95-107.
    • (2003) Mol. Immunol , vol.40 , pp. 95-107
    • Jarva, H.1    Jokiranta, T.S.2    Wurzner, R.3    Meri, S.4
  • 34
    • 9244239222 scopus 로고    scopus 로고
    • BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype
    • Kawabata, H., S. J. Norris, and H. Watanabe. 2004. BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype. Infect. Immun. 72:7147-7154.
    • (2004) Infect. Immun , vol.72 , pp. 7147-7154
    • Kawabata, H.1    Norris, S.J.2    Watanabe, H.3
  • 36
    • 1642535449 scopus 로고    scopus 로고
    • Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins
    • Kraiczy, P., J. Hellwage, C. Skerka, H. Becker, M. Kirschfink, M. M. Simon, V. Brade, P. F. Zipfel, and R. Wallich. 2004. Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins. J. Biol. Chem. 279:2421-2429.
    • (2004) J. Biol. Chem , vol.279 , pp. 2421-2429
    • Kraiczy, P.1    Hellwage, J.2    Skerka, C.3    Becker, H.4    Kirschfink, M.5    Simon, M.M.6    Brade, V.7    Zipfel, P.F.8    Wallich, R.9
  • 37
    • 0037351707 scopus 로고    scopus 로고
    • Immune evasion of Borrelia burgdorferi: Mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family
    • Kraiczy, P., J. Hellwage, C. Skerka, M. Kirschfink, V. Brade, P. F. Zipfel, and R. Wallich. 2003. Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family. Eur. J. Immunol. 33:697-707.
    • (2003) Eur. J. Immunol , vol.33 , pp. 697-707
    • Kraiczy, P.1    Hellwage, J.2    Skerka, C.3    Kirschfink, M.4    Brade, V.5    Zipfel, P.F.6    Wallich, R.7
  • 38
  • 39
    • 0035185119 scopus 로고    scopus 로고
    • Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferi
    • Kraiczy, P., C. Skerka, V. Brade, and P. F. Zipfel. 2001. Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferi. Infect. Immun. 69:7800-7809.
    • (2001) Infect. Immun , vol.69 , pp. 7800-7809
    • Kraiczy, P.1    Skerka, C.2    Brade, V.3    Zipfel, P.F.4
  • 40
    • 0034977067 scopus 로고    scopus 로고
    • Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and factor H
    • Kraiczy, P., C. Skerka, M. Kirschfink, V. Brade, and P. F. Zipfel. 2001. Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and factor H. Eur. J. Immunol. 31:1674-1684.
    • (2001) Eur. J. Immunol , vol.31 , pp. 1674-1684
    • Kraiczy, P.1    Skerka, C.2    Kirschfink, M.3    Brade, V.4    Zipfel, P.F.5
  • 41
    • 0035095224 scopus 로고    scopus 로고
    • Mechanism of complement resistance of pathogenic Borrelia burgdorferi isolates
    • Kraiczy, P., C. Skerka, M. Kirschfink, P. F. Zipfel, and V. Brade. 2001. Mechanism of complement resistance of pathogenic Borrelia burgdorferi isolates. Int. Immunopharmacol. 1:393-401.
    • (2001) Int. Immunopharmacol , vol.1 , pp. 393-401
    • Kraiczy, P.1    Skerka, C.2    Kirschfink, M.3    Zipfel, P.F.4    Brade, V.5
  • 43
    • 0035168567 scopus 로고    scopus 로고
    • Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1
    • Labandeira-Rey, M., and J. T. Skare. 2001. Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1. Infect. Immun. 69:446-455.
    • (2001) Infect. Immun , vol.69 , pp. 446-455
    • Labandeira-Rey, M.1    Skare, J.T.2
  • 44
    • 0026039295 scopus 로고
    • Lyme borreliosis: Relation of its causative agent to its vectors and hosts in North America and Europe
    • Lane, R. S., J. Piesman, and W. Burgdorfer. 1991. Lyme borreliosis: relation of its causative agent to its vectors and hosts in North America and Europe. Annu. Rev. Entomol. 36:587-609.
    • (1991) Annu. Rev. Entomol , vol.36 , pp. 587-609
    • Lane, R.S.1    Piesman, J.2    Burgdorfer, W.3
  • 45
    • 11244308148 scopus 로고    scopus 로고
    • Quantitative analysis of Borrelia burgdorferi gene expression in naturally (tick) infected mouse strains
    • Lederer, S., C. Brenner, T. Stehle, L. Gern, R. Wallich, and M. M. Simon. 2005. Quantitative analysis of Borrelia burgdorferi gene expression in naturally (tick) infected mouse strains. Med. Microbiol. Immunol. 194:81-90.
    • (2005) Med. Microbiol. Immunol , vol.194 , pp. 81-90
    • Lederer, S.1    Brenner, C.2    Stehle, T.3    Gern, L.4    Wallich, R.5    Simon, M.M.6
  • 46
    • 33646370724 scopus 로고    scopus 로고
    • Evidence that the BBA68 protein (BbCRASP-1) of the Lyme disease spirochetes does not contribute to factor H-mediated immune evasion in humans and other animals
    • McDowell, J. V., K. M. Hovis, H. Zhang, E. Tran, J. Lankford, and R. T. Marconi. 2006. Evidence that the BBA68 protein (BbCRASP-1) of the Lyme disease spirochetes does not contribute to factor H-mediated immune evasion in humans and other animals. Infect. Immun. 74:3030-3034.
    • (2006) Infect. Immun , vol.74 , pp. 3030-3034
    • McDowell, J.V.1    Hovis, K.M.2    Zhang, H.3    Tran, E.4    Lankford, J.5    Marconi, R.T.6
  • 47
    • 0035010058 scopus 로고    scopus 로고
    • Analysis of mechanisms associated with loss of infectivity of clonal populations of Borrelia burgdorferi B31MI
    • McDowell, J. V., S. Y. Sung, M. Labandeira-Rey, J. T. Skare, and R. T. Marconi. 2001. Analysis of mechanisms associated with loss of infectivity of clonal populations of Borrelia burgdorferi B31MI. Infect. Immun. 69:3670-3677.
    • (2001) Infect. Immun , vol.69 , pp. 3670-3677
    • McDowell, J.V.1    Sung, S.Y.2    Labandeira-Rey, M.3    Skare, J.T.4    Marconi, R.T.5
  • 48
    • 0037512361 scopus 로고    scopus 로고
    • Comprehensive analysis of the factor H binding capabilities of Borrelia species associated with Lyme disease: Delineation of two distinct classes of factor H binding proteins
    • McDowell, J. V., J. Wolfgang, E. Tran, M. S. Metts, D. Hamilton, and R. T. Marconi. 2003. Comprehensive analysis of the factor H binding capabilities of Borrelia species associated with Lyme disease: delineation of two distinct classes of factor H binding proteins. Infect. Immun. 71:3597-3602.
    • (2003) Infect. Immun , vol.71 , pp. 3597-3602
    • McDowell, J.V.1    Wolfgang, J.2    Tran, E.3    Metts, M.S.4    Hamilton, D.5    Marconi, R.T.6
  • 49
    • 0037512362 scopus 로고    scopus 로고
    • Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice
    • Metts, M. S., J. V. McDowell, M. Theisen, P. R. Hansen, and R. T. Marconi. 2003. Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice. Infect. Immun. 71:3587-3596.
    • (2003) Infect. Immun , vol.71 , pp. 3587-3596
    • Metts, M.S.1    McDowell, J.V.2    Theisen, M.3    Hansen, P.R.4    Marconi, R.T.5
  • 51
    • 0017704496 scopus 로고
    • Human complement C3b inactivator: Isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution
    • Pangburn, M. K., R. D. Schreiber, and H. J. Muller-Eberhard. 1977. Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution. J. Exp. Med. 146:257-270.
    • (1977) J. Exp. Med , vol.146 , pp. 257-270
    • Pangburn, M.K.1    Schreiber, R.D.2    Muller-Eberhard, H.J.3
  • 52
    • 0036699540 scopus 로고    scopus 로고
    • Uncontrolled C3 activation causes membrano-proliferative glomerulonephritis in mice deficient in complement factor H
    • Pickering, M. C., H. T. Cook, J. Warren, A. E. Bygrave, J. Moss, M. J. Walport, and M. Botto. 2002. Uncontrolled C3 activation causes membrano-proliferative glomerulonephritis in mice deficient in complement factor H. Nat. Genet. 31:424-428.
    • (2002) Nat. Genet , vol.31 , pp. 424-428
    • Pickering, M.C.1    Cook, H.T.2    Warren, J.3    Bygrave, A.E.4    Moss, J.5    Walport, M.J.6    Botto, M.7
  • 53
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser, J. E., and S. J. Norris. 2000. Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc. Natl. Acad. Sci. USA 97:13865-13870.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 54
    • 0028057599 scopus 로고
    • Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy
    • Radolf, J. D., K. W. Bourell, D. R. Akins, J. S. Brusca, and M. V. Norgard. 1994. Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy. J. Bacteriol. 176:21-31.
    • (1994) J. Bacteriol , vol.176 , pp. 21-31
    • Radolf, J.D.1    Bourell, K.W.2    Akins, D.R.3    Brusca, J.S.4    Norgard, M.V.5
  • 55
    • 0032473556 scopus 로고    scopus 로고
    • A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae
    • Ram, S., A. K. Sharma, S. D. Simpson, S. Gulati, D. P. McQuillen, M. K. Pangburn, and P. A. Rice. 1998. A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae. J. Exp. Med. 187:743-752.
    • (1998) J. Exp. Med , vol.187 , pp. 743-752
    • Ram, S.1    Sharma, A.K.2    Simpson, S.D.3    Gulati, S.4    McQuillen, D.P.5    Pangburn, M.K.6    Rice, P.A.7
  • 56
    • 35648980024 scopus 로고    scopus 로고
    • Delineation of species-specific binding properties of the CspZ protein (BBH06) of Lyme disease spirochetes: Evidence for new contributions to the pathogenesis of Borrelia spp
    • Rogers, E. A., and R. T. Marconi. 2007. Delineation of species-specific binding properties of the CspZ protein (BBH06) of Lyme disease spirochetes: evidence for new contributions to the pathogenesis of Borrelia spp. Infect. Immun. 75:5272-5281.
    • (2007) Infect. Immun , vol.75 , pp. 5272-5281
    • Rogers, E.A.1    Marconi, R.T.2
  • 57
    • 33845509034 scopus 로고    scopus 로고
    • Borrelia burgdorferi complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes is expressed in humans and induces antibody responses restricted to nondenatured structural determinants
    • Rossmann, E., V. Kitiratschky, H. Hofmann, P. Kraiczy, M. M. Simon, and R. Wallich. 2006. Borrelia burgdorferi complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes is expressed in humans and induces antibody responses restricted to nondenatured structural determinants. Infect. Immun. 74:7024-7028.
    • (2006) Infect. Immun , vol.74 , pp. 7024-7028
    • Rossmann, E.1    Kitiratschky, V.2    Hofmann, H.3    Kraiczy, P.4    Simon, M.M.5    Wallich, R.6
  • 58
    • 0029200874 scopus 로고
    • Electrotransformation of the spirochete Borrelia burgdorferi
    • Samuels, D. S. 1995. Electrotransformation of the spirochete Borrelia burgdorferi. Methods Mol. Biol. 47:253-259.
    • (1995) Methods Mol. Biol , vol.47 , pp. 253-259
    • Samuels, D.S.1
  • 59
    • 58049216337 scopus 로고    scopus 로고
    • Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1
    • Siegel, C., J. Schreiber, K. Haupt, C. Skerka, V. Brade, M. M. Simon, B. Stevenson, R. Wallich, P. F. Zipfel, and P. Kraiczy. 2008. Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1. J. Biol. Chem. 283:34855-34863.
    • (2008) J. Biol. Chem , vol.283 , pp. 34855-34863
    • Siegel, C.1    Schreiber, J.2    Haupt, K.3    Skerka, C.4    Brade, V.5    Simon, M.M.6    Stevenson, B.7    Wallich, R.8    Zipfel, P.F.9    Kraiczy, P.10
  • 60
    • 0024362494 scopus 로고
    • Lyme disease
    • Steere, A. C. 1989. Lyme disease. N. Engl. J. Med. 321:586-597.
    • (1989) N. Engl. J. Med , vol.321 , pp. 586-597
    • Steere, A.C.1
  • 61
    • 0001955132 scopus 로고    scopus 로고
    • Borrelia burgdorferi (Lyme disease, Lyme borreliosis)
    • G. L. Mandell, J. E. Bennett, and R. Dolin ed, Churchill Livingstone, Philadelphia, PA
    • Steere, A. C. 2005. Borrelia burgdorferi (Lyme disease, Lyme borreliosis), p. 2798-2809. In G. L. Mandell, J. E. Bennett, and R. Dolin (ed.), Principles and practice of infectious diseases. Churchill Livingstone, Philadelphia, PA.
    • (2005) Principles and practice of infectious diseases , pp. 2798-2809
    • Steere, A.C.1
  • 63
    • 0036156137 scopus 로고    scopus 로고
    • Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: A possible mechanism underlying the expansive host range of Lyme disease spirochetes
    • Stevenson, B., N. El Hage, M. A. Hines, J. C. Miller, and K. Babb. 2002. Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: a possible mechanism underlying the expansive host range of Lyme disease spirochetes. Infect. Immun. 70:491-497.
    • (2002) Infect. Immun , vol.70 , pp. 491-497
    • Stevenson, B.1    El Hage, N.2    Hines, M.A.3    Miller, J.C.4    Babb, K.5
  • 64
    • 0028828202 scopus 로고
    • Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi
    • Stevenson, B., T. G. Schwan, and P. A. Rosa. 1995. Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi. Infect. Immun. 63:4535-4539.
    • (1995) Infect. Immun , vol.63 , pp. 4535-4539
    • Stevenson, B.1    Schwan, T.G.2    Rosa, P.A.3
  • 65
    • 33749019718 scopus 로고    scopus 로고
    • Comparative genome hybridization reveals substantial variation among clinical isolates of Borrelia burgdorferi sensu stricto with different pathogenic properties
    • Terekhova, D., R. Iyer, G. P. Wormser, and I. Schwartz. 2006. Comparative genome hybridization reveals substantial variation among clinical isolates of Borrelia burgdorferi sensu stricto with different pathogenic properties. J. Bacteriol. 188:6124-6134.
    • (2006) J. Bacteriol , vol.188 , pp. 6124-6134
    • Terekhova, D.1    Iyer, R.2    Wormser, G.P.3    Schwartz, I.4
  • 66
    • 33847718736 scopus 로고    scopus 로고
    • Rapid clearance of Lyme disease spirochetes lacking OspC from skin
    • Tilly, K., A. Bestor, M. W. Jewett, and P. Rosa. 2007. Rapid clearance of Lyme disease spirochetes lacking OspC from skin. Infect. Immun. 75:1517-1519.
    • (2007) Infect. Immun , vol.75 , pp. 1517-1519
    • Tilly, K.1    Bestor, A.2    Jewett, M.W.3    Rosa, P.4
  • 67
    • 16244399154 scopus 로고    scopus 로고
    • Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia afzelii and Borrelia garinii
    • Wallich, R., J. Pattathu, V. Kitiratschky, C. Brenner, P. F. Zipfel, V. Brade, M. M. Simon, and P. Kraiczy. 2005. Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia afzelii and Borrelia garinii. Infect. Immun. 73:2351-2359.
    • (2005) Infect. Immun , vol.73 , pp. 2351-2359
    • Wallich, R.1    Pattathu, J.2    Kitiratschky, V.3    Brenner, C.4    Zipfel, P.F.5    Brade, V.6    Simon, M.M.7    Kraiczy, P.8
  • 69
    • 45149123209 scopus 로고    scopus 로고
    • Essential protective role attributed to the surface lipoproteins of Borrelia burgdorferi against innate defences
    • Xu, Q., K. McShan, and F. T. Liang. 2008. Essential protective role attributed to the surface lipoproteins of Borrelia burgdorferi against innate defences. Mol. Microbiol. 69:15-29.
    • (2008) Mol. Microbiol , vol.69 , pp. 15-29
    • Xu, Q.1    McShan, K.2    Liang, F.T.3
  • 70
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang, X. F., U. Pal, S. M. Alani, E. Fikrig, and M. V. Norgard. 2004. Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J. Exp. Med. 199:641-648.
    • (2004) J. Exp. Med , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5


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