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Volumn 74, Issue 12, 2006, Pages 7024-7028

Borrelia burgdorferi complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes is expressed in humans and induces antibody responses restricted to nondenatured structural determinants

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BACTERIAL PROTEIN; COMPLEMENT FACTOR H; COMPLEMENT REGULATOR ACQUIRING SURFACE PROTEIN 1;

EID: 33845509034     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01028-06     Document Type: Article
Times cited : (23)

References (29)
  • 1
    • 0036784619 scopus 로고    scopus 로고
    • Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs
    • Alitalo, A., T. Meri, H. Lankinen, I. Seppala, P. Lahdenne, P. S. Hefty, D. Akins, and S. Meri. 2002. Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs. J. Immunol. 169:3847-3853.
    • (2002) J. Immunol. , vol.169 , pp. 3847-3853
    • Alitalo, A.1    Meri, T.2    Lankinen, H.3    Seppala, I.4    Lahdenne, P.5    Hefty, P.S.6    Akins, D.7    Meri, S.8
  • 3
    • 0037447108 scopus 로고    scopus 로고
    • Serodiagnosis of Lyme disease by kinetic enzyme-linked immunosor-bent assay using recombinant VlsE1 or peptide antigens of Borrelia burgdor-feri compared with 2-tiered testing using whole-cell lysates
    • Bacon, R. M., B. J. Biggerstaff, M. E. Schriefer, R. D. Gilmore, Jr., M. T. Philipp, A. C. Steere, G. P. Wormser, A. R. Marques, and B. J. Johnson. 2003. Serodiagnosis of Lyme disease by kinetic enzyme-linked immunosor-bent assay using recombinant VlsE1 or peptide antigens of Borrelia burgdor-feri compared with 2-tiered testing using whole-cell lysates. J. Infect. Dis. 187:1187-1199.
    • (2003) J. Infect. Dis. , vol.187 , pp. 1187-1199
    • Bacon, R.M.1    Biggerstaff, B.J.2    Schriefer, M.E.3    Gilmore Jr., R.D.4    Philipp, M.T.5    Steere, A.C.6    Wormser, G.P.7    Marques, A.R.8    Johnson, B.J.9
  • 4
    • 0038104769 scopus 로고    scopus 로고
    • Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals
    • Brooks, C. S., P. S. Hefty, S. E. Jolliff, and D. R. Akins. 2003. Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect Immun. 71:3371-3383.
    • (2003) Infect Immun. , vol.71 , pp. 3371-3383
    • Brooks, C.S.1    Hefty, P.S.2    Jolliff, S.E.3    Akins, D.R.4
  • 5
    • 23844518311 scopus 로고    scopus 로고
    • Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi
    • Brooks, C. S., S. R. Vuppala, A. M. Jett, A. Alitalo, S. Meri, and D. R. Akins. 2005. Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi. J. Immunol. 175:3299-3308.
    • (2005) J. Immunol. , vol.175 , pp. 3299-3308
    • Brooks, C.S.1    Vuppala, S.R.2    Jett, A.M.3    Alitalo, A.4    Meri, S.5    Akins, D.R.6
  • 7
    • 23744471632 scopus 로고    scopus 로고
    • Evaluation of a novel line blot immunoassay for the detection of antibodies to extractable nuclear antigens
    • Damoiseaux, J., K. Boesten, J. Giesen, J. Austen, and J. W. Tervaert. 2005. Evaluation of a novel line blot immunoassay for the detection of antibodies to extractable nuclear antigens. Ann. N. Y. Acad. Sci. 1050:340-347.
    • (2005) Ann. N. Y. Acad. Sci. , vol.1050 , pp. 340-347
    • Damoiseaux, J.1    Boesten, K.2    Giesen, J.3    Austen, J.4    Tervaert, J.W.5
  • 9
    • 0027969061 scopus 로고
    • Demonstration of Borrelia burgdorferi DNA in urine samples from healthy humans whose sera contain B. burgdorferi-specific antibodies
    • Karch, H., H. I. Huppertz, M. Bohme, H. Schmidt, D. Wiebecke, and A. Schwarzkopf. 1994. Demonstration of Borrelia burgdorferi DNA in urine samples from healthy humans whose sera contain B. burgdorferi-specific antibodies. J. Clin. Microbiol. 32:2312-2314.
    • (1994) J. Clin. Microbiol. , vol.32 , pp. 2312-2314
    • Karch, H.1    Huppertz, H.I.2    Bohme, M.3    Schmidt, H.4    Wiebecke, D.5    Schwarzkopf, A.6
  • 10
    • 1642535449 scopus 로고    scopus 로고
    • Complement resistance of Bonella burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins
    • Kraiczy, P., J. Hellwage, C. Skerka, H. Becker, M. Kirschfink, M. M. Simon, V. Brade, P. F. Zipfel, and R. Wallich. 2004. Complement resistance of Bonella burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins. J. Biol. Chem. 279:2421-2429.
    • (2004) J. Biol. Chem. , vol.279 , pp. 2421-2429
    • Kraiczy, P.1    Hellwage, J.2    Skerka, C.3    Becker, H.4    Kirschfink, M.5    Simon, M.M.6    Brade, V.7    Zipfel, P.F.8    Wallich, R.9
  • 11
    • 0037351707 scopus 로고    scopus 로고
    • Immune evasion of Borrelia burgdorferi: Mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family
    • Kraiczy, P., J. Hellwage, C. Skerka, M. Kirschfink, V. Brade, P. F. Zipfel, and R. Wallich. 2003. Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family. Eur. J. Immunol. 33:697-707.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 697-707
    • Kraiczy, P.1    Hellwage, J.2    Skerka, C.3    Kirschfink, M.4    Brade, V.5    Zipfel, P.F.6    Wallich, R.7
  • 12
    • 0035185119 scopus 로고    scopus 로고
    • Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferi
    • Kraiczy, P., C. Skerka, V. Brade, and P. F. Zipfel. 2001. Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferi. Infect. Immun. 69:7800-7809.
    • (2001) Infect. Immun. , vol.69 , pp. 7800-7809
    • Kraiczy, P.1    Skerka, C.2    Brade, V.3    Zipfel, P.F.4
  • 13
    • 0034977067 scopus 로고    scopus 로고
    • Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and factor H
    • Kraiczy, P., C. Skerka, M. Kirschfink, V. Brade, and P. F. Zipfel. 2001. Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and factor H. Eur. J. Immunol. 31:1674-1684.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1674-1684
    • Kraiczy, P.1    Skerka, C.2    Kirschfink, M.3    Brade, V.4    Zipfel, P.F.5
  • 14
    • 0037205672 scopus 로고    scopus 로고
    • Complement regulator-acquiring surface proteins of Borrelia burgdorferi: A new protein family involved in complement resistance
    • Kraiczy, P., C. Skerka, P. F. Zipfel, and V. Brade. 2002. Complement regulator-acquiring surface proteins of Borrelia burgdorferi: a new protein family involved in complement resistance. Wien. Klin. Wochenschr. 114:568-573.
    • (2002) Wien. Klin. Wochenschr. , vol.114 , pp. 568-573
    • Kraiczy, P.1    Skerka, C.2    Zipfel, P.F.3    Brade, V.4
  • 15
    • 0028875543 scopus 로고
    • Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H1
    • Kuhn, S., C. Skerka, and P. F. Zipfel. 1995. Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H1. J. Immunol. 155:5663-5670.
    • (1995) J. Immunol. , vol.155 , pp. 5663-5670
    • Kuhn, S.1    Skerka, C.2    Zipfel, P.F.3
  • 17
    • 0042967596 scopus 로고    scopus 로고
    • Simultaneous identification of various antinuclear antibodies using an automated multiparameter line immunoassay system
    • Lopez-Longo, F. J., M. Rodriguez-Mahou, M. Escalona-Monge, C. M. Gonzalez, I. Monteagudo, and L. Carreno-Perez. 2003. Simultaneous identification of various antinuclear antibodies using an automated multiparameter line immunoassay system. Lupus 12:623-629.
    • (2003) Lupus , vol.12 , pp. 623-629
    • Lopez-Longo, F.J.1    Rodriguez-Mahou, M.2    Escalona-Monge, M.3    Gonzalez, C.M.4    Monteagudo, I.5    Carreno-Perez, L.6
  • 18
    • 33646370724 scopus 로고    scopus 로고
    • Evidence that the BBA68 protein (BbCRASP-1) of the Lyme disease spirochetes does not contribute to factor H-mediated immune evasion in humans and other animals
    • McDowell, J. V., K. M. Hovis, H. Zhang, E. Tran, J. Lankford, and R. T. Marconi. 2006. Evidence that the BBA68 protein (BbCRASP-1) of the Lyme disease spirochetes does not contribute to factor H-mediated immune evasion in humans and other animals. Infect. Immun. 74:3030-3034.
    • (2006) Infect. Immun. , vol.74 , pp. 3030-3034
    • McDowell, J.V.1    Hovis, K.M.2    Zhang, H.3    Tran, E.4    Lankford, J.5    Marconi, R.T.6
  • 19
    • 0037512361 scopus 로고    scopus 로고
    • Comprehensive analysis of the factor H binding capabilities of Borrelia species associated with Lyme disease: Delineation of two distinct classes of factor H binding proteins
    • McDowell, J. V., J. Wolfgang, E. Tran, M. S. Metts, D. Hamilton, and R. T. Marconi. 2003. Comprehensive analysis of the factor H binding capabilities of Borrelia species associated with Lyme disease: delineation of two distinct classes of factor H binding proteins. Infect. Immun. 71:3597-3602.
    • (2003) Infect. Immun. , vol.71 , pp. 3597-3602
    • McDowell, J.V.1    Wolfgang, J.2    Tran, E.3    Metts, M.S.4    Hamilton, D.5    Marconi, R.T.6
  • 20
    • 0037512362 scopus 로고    scopus 로고
    • Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice
    • Metts, M. S., J. V. McDowell, M. Theisen, P. R. Hansen, and R. T. Marconi. 2003. Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice. Infect. Immun. 71:3587-3596.
    • (2003) Infect. Immun. , vol.71 , pp. 3587-3596
    • Metts, M.S.1    McDowell, J.V.2    Theisen, M.3    Hansen, P.R.4    Marconi, R.T.5
  • 21
    • 0017704496 scopus 로고
    • Human complement C3b inactivator: Isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution
    • Pangburn, M. K., R. D. Schreiber, and H. J. Muller-Eberhard. 1977. Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution. J. Exp. Med. 146:257-270.
    • (1977) J. Exp. Med. , vol.146 , pp. 257-270
    • Pangburn, M.K.1    Schreiber, R.D.2    Muller-Eberhard, H.J.3
  • 22
    • 0024362494 scopus 로고
    • Lyme disease
    • Steere, A. C. 1989. Lyme disease. N. Engl. J. Med. 321:586-596.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 586-596
    • Steere, A.C.1
  • 23
    • 0036156137 scopus 로고    scopus 로고
    • Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: A possible mechanism underlying the expansive host range of Lyme disease spirochetes
    • Stevenson, B., N. El-Hage, M. A. Hines, J. C. Miller, and K. Babb. 2002. Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: a possible mechanism underlying the expansive host range of Lyme disease spirochetes. Infect. Immun. 70:491-497.
    • (2002) Infect. Immun. , vol.70 , pp. 491-497
    • Stevenson, B.1    El-Hage, N.2    Hines, M.A.3    Miller, J.C.4    Babb, K.5
  • 24
    • 27744573129 scopus 로고    scopus 로고
    • Borrelia burgdorferi regulates expression of complement regulator-acquiring surface protein 1 during the mammal-tick infection cycle
    • von Lackum, K., J. C. Miller, T. Bykowski, S. P. Riley, M. E. Woodman, V. Brade, P. Kraiczy, B. Stevenson, and R. Wallich. 2005. Borrelia burgdorferi regulates expression of complement regulator-acquiring surface protein 1 during the mammal-tick infection cycle. Infect. Immun. 73:7398-7405.
    • (2005) Infect. Immun. , vol.73 , pp. 7398-7405
    • Von Lackum, K.1    Miller, J.C.2    Bykowski, T.3    Riley, S.P.4    Woodman, M.E.5    Brade, V.6    Kraiczy, P.7    Stevenson, B.8    Wallich, R.9
  • 25
    • 0029122852 scopus 로고
    • Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo
    • Wallich, R., C. Brenner, M. D. Kramer, and M. M. Simon. 1995. Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo. Infect. Immun. 63:3327-3335.
    • (1995) Infect. Immun. , vol.63 , pp. 3327-3335
    • Wallich, R.1    Brenner, C.2    Kramer, M.D.3    Simon, M.M.4
  • 26
    • 0037352748 scopus 로고    scopus 로고
    • Artificial-infection protocols allow immuno-detection of novel Borrelia burgdorferi antigens suitable as vaccine candidates against Lyme disease
    • Wallich, R., O. Jahraus, T. Stehle, T. T. Tran, C. Brenner, H. Hofmann, L. Gern, and M. M. Simon. 2003. Artificial-infection protocols allow immuno-detection of novel Borrelia burgdorferi antigens suitable as vaccine candidates against Lyme disease. Eur. J. Immunol. 33:708-719.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 708-719
    • Wallich, R.1    Jahraus, O.2    Stehle, T.3    Tran, T.T.4    Brenner, C.5    Hofmann, H.6    Gern, L.7    Simon, M.M.8
  • 27
    • 16244399154 scopus 로고    scopus 로고
    • Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia aftelii and Borrelia garinii
    • Wallich, R., J. Pattathu, V. Kitiratschky, C. Brenner, P. F. Zipfel, V. Brade, M. M. Simon, and P. Kraiczy. 2005. Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia aftelii and Borrelia garinii. Infect. Immun. 73:2351-2359.
    • (2005) Infect. Immun. , vol.73 , pp. 2351-2359
    • Wallich, R.1    Pattathu, J.2    Kitiratschky, V.3    Brenner, C.4    Zipfel, P.F.5    Brade, V.6    Simon, M.M.7    Kraiczy, P.8
  • 28
    • 0027427164 scopus 로고
    • Molecular and immunological characterization of a novel polymorphic lipoprotein of Borrelia burgdorferi
    • Wallich, R., M. M. Simon, H. Hofmann, S. E. Moter, U. E. Schaible, and M. D. Kramer. 1993. Molecular and immunological characterization of a novel polymorphic lipoprotein of Borrelia burgdorferi. Infect. Immun. 61:4158-4166.
    • (1993) Infect. Immun. , vol.61 , pp. 4158-4166
    • Wallich, R.1    Simon, M.M.2    Hofmann, H.3    Moter, S.E.4    Schaible, U.E.5    Kramer, M.D.6


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