Error-protein metabolism and ageing

Biogerontology

Volumn 10, Issue 4, 2009, Pages 523-529

  Hipkiss, Alan R ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Aging; Chaperone proteins; Error proteins; Mis translation; Mitochondria; Proteases; Proteasomes; Proteolysis; Ribosomes

Indexed keywords

CHAPERONE; MITOCHONDRIAL PROTEIN; PROTEIN; PROTEINASE; REACTIVE OXYGEN METABOLITE; SIRTUIN;

AEROBIC EXERCISE; AGING; ARTICLE; BACTERIAL GROWTH; BIOACCUMULATION; BIOGENESIS; BIOLOGICAL ACTIVITY; CELL AGING; CELL DAMAGE; DIET RESTRICTION; GROWTH RATE; HUMAN; MITOCHONDRIAL RESPIRATION; MOLECULAR DYNAMICS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RIBOSOME;

AGE FACTORS; AGING; ANIMALS; BACTERIA; CALORIC RESTRICTION; CELL PROLIFERATION; DISEASE SUSCEPTIBILITY; EXERCISE; HUMANS; MITOCHONDRIA; MOLECULAR CHAPERONES; PEPTIDE HYDROLASES; PROTEIN BIOSYNTHESIS; PROTEIN STABILITY; PROTEINS; RIBOSOMES; SIRTUINS;

EID: 67649652245     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-008-9188-9     Document Type: Article

References (81)

1. Alemi M, Prigione A, Wong A, Schoenfeld R, DiMauro S, Hirano M, Taroni F, Cortopassi G (2007) Mitochondrial DNA deletions inhibit proteasomal activity and stimulate an autophagic transcript. Free Radic Biol Med 42:32-43
2. Anderson RM, Barger JL, Edwards MG, Braun KH, O'Conner CE, Prolla TA, Weindruch R (2008) Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in caloric restriction and the stress response. Aging Cell 7:101-111
3. Ayala V, Naudi A, Sanz A, Caro P, Portero-Otin M, Barja G, Pamplona R (2007) Dietary protein restriction decreases oxidative damage, peroxidizability index, and mitochondrial complex 1 content in rat liver. J Gerontol A Biol Sci Med Sci 62:352-360
4. Bali P, Pranpat M, Bradner J, Balasis M, Fiscus W, Gua F, Rocha K, Kumaraswamy S, Boyapalle S, Atadja P, Seto E, Bhalla K (2005) Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90. J Biol Chem 250:28729-28734
5. Bergamini E, Cavallini G, Donati A, Gori Z (2007) The role of autophagy in aging. Its essential part in the anti-aging mechanism of caloric restriction. Ann N Y Acad Sci 1114:69-78
6. Bonawitz ND, Chatenay-Lapointe M, Pan Y, Shadel GS (2007) Reduced TOR signalling extends chronological life span via increased respiration and upregulated mitochondrial gene expression. Cell Metab 5:265-277
7. Bota DA, Davies KJA (2001) Protein degradation in mitochondria: implications for oxidative stress, aging and disease: A novel etiological classification of mitochondrial proteolytic disorders. Mitochondrion 1:33-49
8. Bowerman B (2007) C. elegans aging: Proteolysis cuts both ways. Curr Biol 17:R514-R516
9. Broadley SA, Hartl FU (2007) Mitochondrial stress signalling: A pathway unfolds. Trends Cell Biol 18:1-4
10. Bulteau AL, Szweda LI, Friguet B (2006) Mitochondrial protein oxidation and degradation in response to oxidative stress and aging. Exp Gerontol 41:653-657
11. Carrard G, Bulteau A-L, Petropoulos I, Friguet B (2002) Impairment of proteasome structure and function in aging. Int J Biochem Cell Biol 34:1461-1474
12. Chiocchetti A, Zhou J, Zhu H, Karl T, Haubenreisser O, Rinnerthaler M, Heeren G, Oender K, Bauer J, Hintner H, Breitenbach M, Breitenbach-Koller L (2007) Ribosomal proteins Rp110 and Rps6 are potent regulators of yeast replicative life span. Exp Gerontol 42:275-286
13. Chondrogianni N, Gonos ES (2007) Overexpression of hUMP11/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence. Exp Gerontol 42:899-903
14. Chuang SM, Chen L, Lambertson D, Anand M, Kinzy TG, Madura K (2005) Proteasome-mediated degradation of cotranslationally damaged proteins involves translation elongation factor 1A. Mol Cell Biol 25:403-413
15. Conley KE, Marcinek DJ, Villarin J (2007) Mitochondrial dysfunction and age. Curr Opin Clin Nutr Metab Care 10:688-692
16. Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P (2007) mTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcription complex. Nature 450:736-740
17. Dahlmann B (2007) Role of proteasomes in disease. BMC Biochem 8:S3-S15
18. Das R, Ponnappan S, Ponnappan U (2007) Redox regulation of the proteasome in T lymphocytes during aging. Free Radic Biol Med 42:541-551
19. Ding Q, Keller JN (2001) Proteasome inhibition in oxidative stress neurotoxicity: Implications for heat shock proteins. J Neurochem 77:1010-1017
20. Ding Q, Dimayuga E, Markesbery WR, Keller JN (2006) Proteasome inhibition induces reversible impairments in protein synthesis. FASEB J 20:1055-1063
21. Ding Q, Cecarini V, Keller JN (2007) Interplay between protein synthesis and degradation in the CNS: Physiological and pathological implications. Trends Neurosci 30:31-36
22. Dohmen RJ, Willers I, Marques AJ (2007) Biting the hands that feeds: Rpn4-dependent feedback regulation of proteasome function. Biochim Biophys Acta 1773:1599-1604
23. Donati A (2006) The involvement of macroautophagy in aging and anti-aging interventions. Mol Aspects Med 27:455-470
24. Erjavec N, Larsson L, Grantham J, Nystrom T (2007) Accelerated aging and failure to segregate damaged protein in Sir2 mutants can be suppressed by overproducing the protein aggregation remodelling factor Hsp 104p. Genes Dev 21:2410-2422
25. Frier CF, Locke M (2007) Heat stress inhibits skeletal muscle hypertrophy. Cell Stress Chaperones 12:132-141
26. Glickman MH, Raveh D (2005) Proteasome plasticity. FEBS Lett 579:3214-3223
27. Guarente L (2008) Mitochondria - a nexus for aging, calorie restriction and sirtuins. Cell 132:171-175
28. Hansen M, Taubert T, Crawford D, Libina N, Lee S-J, Kenyon C (2007) Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6:95-110
29. Haynes CM, Petrova K, Benedetti C, Yang Y, Ron D (2007) ClpP mediates activation of a mitochondrial unfolded response in C. elegans. Dev Cell 4:467-480
30. Hellstrom-Lindahl E, Ravid R, Nordberg A (2008) Age-dependent decline of neprilysin in Alzheimer's disease and normal brain: Inverse correlation with Aβ levels. Neurobiol Aging 29:210-221
31. Hiona A, Leeuwenburgh C (2008) The role of mitochondrial DNA mutations in aging and sarcopenia: Implications for the mitochondrial vicious cycle theory of aging. Exp Gerontol 43:24-33
32. Hipkiss AR (2003a) Do developmentally-related changes in constitutive proteolysis affect aberrant protein accumulation and generation of the aged phenotype? Mech Ageing Dev 124:575-579
33. Hipkiss AR (2003b) Errors, mitochondrial dysfunction and ageing. Biogerontology 4:397-400
34. Hipkiss AR (2006) Accumulation of altered proteins and ageing: Causes and effects. Exp Gerontol 41:464-473
35. Hipkiss AR (2007) On why decreasing protein synthesis can increase lifespan. Mech Ageing Dev 128:412-414
36. Holbrook MA, Menninger JR (2002) Erythromycin slows aging in Saccharomyces cerevisiae. J Gerontol A Biol Sci Med Sci 57A:B29-B36
37. Holliday R, Rattan SIS (1984) Evidence that paromomycin induces premature ageing in human fibroblasts. Monogr Dev Biol 17:221-233
38. Howell N, Elson JL, Chinnery PF, Turnbull DM (2005) mtDNA mutations and common neurodegenerative disorders. Trends Genet 21:583-586
39. Ingraham JL, Maaloe D, Neidhardt FC (1983) Growth of the bacterial cell. Sinauer Associates, Sunderland
40. Ju D, Wang L, Mao X, Xie Y (2004) Homeostatic regulation of the proteasome via an Rpn4-dependent feedback circuit. Biochem Biophys Res Commun 321:51-57
41. Kalogeraki A, Giannikaki E, Tzardi M, Kafousi M, Ieromonachou P, Dariviannaki K, Askoxylakis J, Tsiftsis D, Stathopoulos E, Zoras O (2007) Correlation of heat shock protein (HSP70) expression with cell proliferation (MIB1), estrogen receptors (ER) and clinicopathological variables in invasive ductal breast carcinomas. J Exp Clin Cancer Res 26:367-368
42. Kim I, Rodriguex-Enriquez S, Lemasters JJ (2007) Selective degradation of mitochondria by mitophagy. Arch Biochem Biophys 462:245-253
43. Kirkwood TBL, Holliday R, Rosenberger RF (1984) The stability of the cellular translation process. Int Rev Cytol 92:93-132
44. Kleijnen MF, Roelofs J, Park S, Hathaway N, Glickman M, King RW, Finley D (2007) Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites. Nat Struct Mol Biol 14:1180-1186
45. Ksiazek K, Passos J, Olijslagers S, von Zglinicki T (2008) Mitochondrial dysfunction is a possible cause of accelerated senescence of mesothelial cells exposed to high glucose. Biochem Biophys Res Commun 366:793-799
46. Kusmierczyk AR, Kunjappu MJ, Funakoshi M, Hochstrasser M (2008) A multimeric assembly factor controls the formation of alternative 20S proteasomes. Nat Struct Mol Biol 15:237-244
47. Leidhold C, Voos W (2007) Chaperones and proteases - guardians of protein integrity in eukaryotic organelles. Ann N Y Acad Sci 1113:72-86
48. Le Tallec B, Barrault MB, Courbeyrette R, Guerois R, Marsolier-Kerqoat MC, Peyroche A (2007) 20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals. Mol Cell 27:660-674
49. London MK, Keck BI, Ramos PC, Dohmen RJ (2004) Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome. FEBS Lett 567:259-264
50. Major T, von Janowsky B, Ruppert T, Mogk A, Voos W (2006) Proteomic analysis of mitochondrial protein turnover: Identification of novel substrate proteins of the matrix protease Pim1. Mol Cell Biol 26:762-776
51. Martinez-Vicente M, Cuervo AM (2007) Autophagy and neurodegeneration: when the cleaning crew goes on strike. Lancet Neurol 6:352-362
52. Meyer-Luehmann M, Spire-Jones TL, Prada C, Garcia-Alloza M, de Caligon A, Rozkalne A, Koenigsknecht-Talboo J, Holtzman H, Bacskai BJ, Hyman BT (2008) Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer's disease. Nature 451:720-724
53. Miller RA, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock M (2005) Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-1 and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 4:119-125
54. Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thormalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, Hamann A, Becker C, Zeier M, Schwenger V, Miftari N, Humpert P, Hammes HP, Buechler M, Bierhaus A, Brownlee M, Nawroth PP (2008) Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in C. elegans. Aging Cell 7:260-269
55. Naudi A, Caro P, Jove M, Gomez J, Boada J, Ayala V, Portero-Otin M, Barja G, Pamplona R (2007) Methionine restriction decreases endogenous oxidative molecular damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain. Rejuv Res 10:1-11
56. Ngo JK, Davies KJ (2007) Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging. Ann N Y Acad Sci 1119:78-87
57. Otto H, Conz C, Maier P, Suzuki CK, Jeno P, Rucknagel P, Stahl J, Rospert S (2005) The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. Proc Natl Acad Sci USA 102:100064-100069
58. Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, Lithgow GJ, Kapahi P (2007) Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6:111-119
59. Passos JF, Saretzki G, Ahmed S, Nelson G, Richter T, Peters H, Wappler I, Birket MJ, Harold G, Schaeuble K, Birch-Machin MA, Kirkwood TBL, von Zglinicki T (2007) Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol 5:1138-1152
60. Qian S-B, Princiotta MF, Bennink JR, Yewdell JW (2006) Characterization of rapidly degraded polypeptides in mammalian cells reveals a novel layer of nascent protein quality control. J Biol Chem 281:392-400
61. Qiu WQ, Folstein MF (2006) Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: Review and hypothesis. Neurobiol Aging 27:190-198
62. Rakwalska M, Rospert S (2004) The ribosome-bound chaperones RAC and Ssb1/ 2p are required for accurate translation in Saccharomyces cerevisiae. Mol Cell Biol 24:9186-9197
63. Rattan SIS (2003) Transcriptional and translational dysregulation during aging. In: Von Zglinicki T (ed) Aging at the molecular level. Kluwer, Dordrecht, pp 179-191
64. Rattan SIS (2008) Increased molecular damage and heterogeneity as the basis of aging. Biol Chem 389:267-272
65. Reddy PH, Beal MF (2008) Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med 14:45-53
66. Richie JP Jr, Leutzinger Y, Parthasarathy S, Malloy V, Orentreich N, Zimmerman JA (1994) Methionine restriction increases blood glutathione and longevity in F344 rats. FASEB J 8:1303-1307
67. Rodgers JT, Lerin C, Gerhart-Hines Z, Puigserver P (2008) Metabolic adaptations through PGC-1α and SIRT1 pathways. FEBS Lett 582:46-53
68. - cells. FEMS Microbiol Lett 68:19-25
69. Roy H, Ling J, Alfonzo J, Ibba M (2005) Loss of editing activity during the evolution of mitochondria phenylalanyl-tRNA synthetase. J Biol Chem 280:38186-38192
70. Sanz A, Caro P, Ayala V, Portero-Otin M, Pamplona R, Barja G (2006) Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins. FASEB J 20:1064-1073
71. Soh JW, Hotic S, Arking R (2007) Dietary restriction in Drosophila is dependent on mitochondrial efficiency and constrained by pre-existing extended longevity. Mech Ageing Dev 128:581-593
72. Soskic V, Groebe K, Schrattenholz A (2007) Non-enzymic posttranslational protein modification in aging. Exp Gerontol 43:247-257
73. Spence J, Gali RR, Dittmer G, Sherman F, Karin M, Finley D (2000) Cell cycle-regulated modification of the ribosome by a variant multi-ubiquitin chain. Cell 107:67-76
74. Stavreva DA, Kawasaki M, Dundr M, Koberna K, Muller WG, Tsujimura-Takahashi T, Komatsu W, Hayano T, Isobe T, Raska I, Misteli T, Takahashi N, McNally JG (2006) Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol 26:5131-5145
75. Syntichaki P, Troulinaki K, Tavernarakis N (2007) eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature 445:922-926
76. Tatsuta T, Langer T (2008) Quality control of mitochondria: Protection against neurodegeneration and ageing. EMBO J 27:306-314
77. Vernace VA, Arnaud L, Schmidt-Glenewinkel T, Figueiredo-Pereira ME (2007a) Aging perturbs 26S proteasome assembly in Drosophila melanogaster. FASEB J 21:2672-2682
78. Vernace VA, Schmidt-Glenewinkel T, Figueiredo-Pereira ME (2007b) Aging and regulated protein degradation: Who has the UPPer hand? Aging Cell 6:599-606
79. von Janowsky B, Major T, Knapp K, Voos W (2006) The disaggregation activity of the mitochondrial ClpB homolog Hsp78 maintains Hsp70 function during heat stress. J Mol Biol 357:793-807
80. Voos W, Rottgers K (2002) Molecular chaperones as essential mediators of mitochondrial biogenesis. Biochim Biophys Acta 1592:51-62
81. Yashiroda H, Mizushima T, Okamto K, Kameyama T, Hayashi H, Kishimoto T, Niwa S, Kasahara M, Kurimoto E, Sakata E, Takagi K, Suzuki A, Hirana Y, Murata S, Kato K, Yamane T, Tanaka K (2008) Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes. Nat Struct Mol Biol 15:228-236