Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain

Developmental Dynamics

Volumn 238, Issue 7, 2009, Pages 1803-1812

  Moran, Jennifer L ^b,c   Shifley, Emily T ^a   Levorse, John M ^b   Mani, Shyamala ^b,f   Ostmann, Kristin ^a   Perez Balaguer, Ariadna ^a,e   Walker, Dawn M ^a   Vogt, Thomas F ^b,d   Cole, Susan E ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^f NATIONAL BRAIN RESEARCH CENTRE   (India)

Author keywords

Fringe genes; Limb development; Manic fringe knockout; Notch pathway; Somitogenesis

Indexed keywords

COMPLEMENTARY DNA; GENOMIC DNA; GLYCOSYLTRANSFERASE; MESSENGER RNA; NOTCH RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BRAIN DEVELOPMENT; CRANIAL NERVE; EMBRYO; EMBRYO DEVELOPMENT; FRINGE GENE; GENE; GENE DELETION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KNOCKOUT MOUSE; LIMB DEVELOPMENT; MANIC FRINGE GENE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHOMBENCEPHALON; SKELETON;

ANIMALS; BODY PATTERNING; BONE AND BONES; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; EXTREMITIES; FERTILITY; FETAL VIABILITY; GENE DELETION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MULTIGENE FAMILY; PROTEINS; RHOMBENCEPHALON;

MUS; VERTEBRATA;

EID: 67649588261     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21982     Document Type: Article

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