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Volumn 122, Issue 12, 1996, Pages 3851-3861

The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: Implications for the mechanism of apical ridge formation

Author keywords

AER; Apical ectodermal ridge; D V patterning; EN1; FGF8; Limb development; Limbless; SHH; Sonic hedgehog; WNT7A

Indexed keywords

ARTICLE; CHICK EMBRYO; CHICKEN; ECTODERM; EMBRYO; GENE EXPRESSION; LIMB BUD; LIMB DEVELOPMENT; MESODERM; NONHUMAN; PRIORITY JOURNAL;

EID: 0030477866     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (93)

References (65)
  • 1
    • 0344166668 scopus 로고
    • Inbred lines as genetic resources of chickens
    • Abplanalp, H. (1992). Inbred lines as genetic resources of chickens. Poultry Science Review 4, 29-39.
    • (1992) Poultry Science Review , vol.4 , pp. 29-39
    • Abplanalp, H.1
  • 2
    • 0024268322 scopus 로고
    • Initial limb budding is independent of apical ectodermal ridge activity; evidence from a limbless mutant
    • Carrington, J. L. and Fallon. J. F. (1988). Initial limb budding is independent of apical ectodermal ridge activity; evidence from a limbless mutant. Development 104, 361-367.
    • (1988) Development , vol.104 , pp. 361-367
    • Carrington, J.L.1    Fallon, J.F.2
  • 4
    • 0025770771 scopus 로고
    • Expression of the chicken homeobox-containing gene GHox-8 during embryonic chick limb development
    • Coelho, C. N. D., Sumoy, L., Rodgers, B. J., Davidson, D. R., Hill, R. E., Upholt, W. B. and Kosher, R. A. (199la). Expression of the chicken homeobox-containing gene GHox-8 during embryonic chick limb development. Mech. Dev. 34, 143-154.
    • (1991) Mech. Dev. , vol.34 , pp. 143-154
    • Coelho, C.N.D.1    Sumoy, L.2    Rodgers, B.J.3    Davidson, D.R.4    Hill, R.E.5    Upholt, W.B.6    Kosher, R.A.7
  • 5
    • 0026315619 scopus 로고
    • Altered expression of the chicken homeobox-containing genes GHox-7 and Ghox-8 in the limb buds of limbless mutant chick embryos
    • Coelho, C. N. D., Krabbenhoft, K. M., Upholt, W. B., Fallon, J. F. and Kosher, R. A. (1991b). Altered expression of the chicken homeobox-containing genes GHox-7 and Ghox-8 in the limb buds of limbless mutant chick embryos. Development 113, 1487-1293.
    • (1991) Development , vol.113 , pp. 1487-11293
    • Coelho, C.N.D.1    Krabbenhoft, K.M.2    Upholt, W.B.3    Fallon, J.F.4    Kosher, R.A.5
  • 6
    • 0028946304 scopus 로고
    • Fibroblast growth factors induce additional limb development from the flank of chick embryos
    • Cohn, M. J., Izpisúa-Belmonte, J. C., Abud, H., Heath, J. K. and Tickle, C. (1995). Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.
    • (1995) Cell , vol.80 , pp. 739-746
    • Cohn, M.J.1    Izpisúa-Belmonte, J.C.2    Abud, H.3    Heath, J.K.4    Tickle, C.5
  • 7
    • 0030034731 scopus 로고    scopus 로고
    • Roles for FGF8 in the induction, initiation, and maintenance of chick limb development
    • Crossley, P. H., Minowada, G., MacArthur, C. A. and Martin, G. R. (1996a). Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84, 127-136.
    • (1996) Cell , vol.84 , pp. 127-136
    • Crossley, P.H.1    Minowada, G.2    MacArthur, C.A.3    Martin, G.R.4
  • 8
    • 0029960330 scopus 로고    scopus 로고
    • Midbrain development induced by FGF8 in the chick embryo
    • Crossley, P. H., Martinez, S. and Martin, G. R. (1996b). Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.
    • (1996) Nature , vol.380 , pp. 66-68
    • Crossley, P.H.1    Martinez, S.2    Martin, G.R.3
  • 9
    • 0028085623 scopus 로고
    • Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11
    • Davis, A. P. and Capecchi, M. R. (1994). Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Development 120, 2187-2198.
    • (1994) Development , vol.120 , pp. 2187-2198
    • Davis, A.P.1    Capecchi, M.R.2
  • 10
    • 0029963585 scopus 로고    scopus 로고
    • A mutational analysis of the 5′ HoxD genes: Dissection of genetic interactions during limb development in the mouse
    • Davis, A. P. and Capecchi, M. R. (1996). A mutational analysis of the 5′ HoxD genes: dissection of genetic interactions during limb development in the mouse. Development 122, 1175-1185.
    • (1996) Development , vol.122 , pp. 1175-1185
    • Davis, A.P.1    Capecchi, M.R.2
  • 11
    • 0026101890 scopus 로고
    • Examining pattern formation in mouse, chicken and frog embryos with an En-specitic antiserum
    • Davis, C. A., Holmyard, D. P., Millen, K. J. and Joyner, A. L. (1991) Examining pattern formation in mouse, chicken and frog embryos with an En-specitic antiserum. Development 111, 287-298.
    • (1991) Development , vol.111 , pp. 287-298
    • Davis, C.A.1    Holmyard, D.P.2    Millen, K.J.3    Joyner, A.L.4
  • 12
    • 0029911618 scopus 로고    scopus 로고
    • IGF-I, insulin and Fgfs induce outgrowth of the limb buds of amelic mutant chick embryos
    • Dealy, C.N. and Kosher, R.A. (1996). IGF-I, insulin and Fgfs induce outgrowth of the limb buds of amelic mutant chick embryos. Development 122, 1323-1330.
    • (1996) Development , vol.122 , pp. 1323-1330
    • Dealy, C.N.1    Kosher, R.A.2
  • 13
    • 0027441061 scopus 로고
    • Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes
    • Dealy, C. N., Roth, A., Ferrari, D., Brown, A. M. C. and Kosher, R. A. (1993). Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes. Mech. Dev. 43, 175-186.
    • (1993) Mech. Dev. , vol.43 , pp. 175-186
    • Dealy, C.N.1    Roth, A.2    Ferrari, D.3    Brown, A.M.C.4    Kosher, R.A.5
  • 14
    • 0027358721 scopus 로고
    • Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
    • Dollé, P., Dierich, A., LeMeur, M., Schimmang, T., Schuhbaur, N., Chambon. P. and Duboule, D. (1993). Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell 75, 431-441.
    • (1993) Cell , vol.75 , pp. 431-441
    • Dollé, P.1    Dierich, A.2    LeMeur, M.3    Schimmang, T.4    Schuhbaur, N.5    Chambon, P.6    Duboule, D.7
  • 16
    • 0028266824 scopus 로고
    • FGF-2: Apical ectodermal ridge growth signal for chick limb development
    • Fallon, J. F., López., A., Ros, M. A., Savage. M. P., Olwin, B. B. and Simandl, B. K. (1994). FGF-2: Apical ectodermal ridge growth signal for chick limb development. Science 264, 104-107.
    • (1994) Science , vol.264 , pp. 104-107
    • Fallon, J.F.1    López, A.2    Ros, M.A.3    Savage, M.P.4    Olwin, B.B.5    Simandl, B.K.6
  • 17
    • 0028921493 scopus 로고
    • Axial skeletal homeosis and forelimb malformations in Hoxd-11 mutant mice
    • Favier, B., LeMeur, M., Chambon, P. and Dollé, P. (1995). Axial skeletal homeosis and forelimb malformations in Hoxd-11 mutant mice. Proc, Natl. Acad. Sci. USA 92, 310-314.
    • (1995) Proc, Natl. Acad. Sci. USA , vol.92 , pp. 310-314
    • Favier, B.1    LeMeur, M.2    Chambon, P.3    Dollé, P.4
  • 18
    • 0028137737 scopus 로고
    • Bone morphogenetic proteins and a signaling pathway that controls patterning in the developing chick limb
    • Francis, P. H., Richardson, M. K., Brickell, P. M. and Tickle, C. (1994). Bone morphogenetic proteins and a signaling pathway that controls patterning in the developing chick limb. Development 120, 209-218.
    • (1994) Development , vol.120 , pp. 209-218
    • Francis, P.H.1    Richardson, M.K.2    Brickell, P.M.3    Tickle, C.4
  • 19
    • 0029034805 scopus 로고
    • Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta3) limb buds: Their relationships in the signalling cascade involved in limb patterning
    • Francis-West, P. H., Robertson, K. E., Ede, D. A., Rodriguez, C., Izpisúa-Belmonte, J.-C., Houston, B., Burt, D. W., Gribbin, C., Brickell, P. M. and Tickle, C. (1995). Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta3) limb buds: their relationships in the signalling cascade involved in limb patterning. Dev. Dynamics 203, 187-197.
    • (1995) Dev. Dynamics , vol.203 , pp. 187-197
    • Francis-West, P.H.1    Robertson, K.E.2    Ede, D.A.3    Rodriguez, C.4    Izpisúa-Belmonte, J.-C.5    Houston, B.6    Burt, D.W.7    Gribbin, C.8    Brickell, P.M.9    Tickle, C.10
  • 20
    • 0026653410 scopus 로고
    • Expression patterns of Engrailed-like proteins inthe chick embryo
    • Gardner, C. A. and Barald, K. F. (1992). Expression patterns of Engrailed-like proteins inthe chick embryo. Dev. Dynamics 193, 370-388.
    • (1992) Dev. Dynamics , vol.193 , pp. 370-388
    • Gardner, C.A.1    Barald, K.F.2
  • 21
    • 0023490460 scopus 로고
    • The ectodermal control of mesodermal patterns of differentiation in the developing chick wing
    • Geduspan, J. S. and MacCabe, J. A. (1987). The ectodermal control of mesodermal patterns of differentiation in the developing chick wing. Dev. Biol. 124, 398-408.
    • (1987) Dev. Biol. , vol.124 , pp. 398-408
    • Geduspan, J.S.1    MacCabe, J.A.2
  • 22
    • 0024344580 scopus 로고
    • Transfer of dorsoventral information from mesoderm to ectoderm at the onset of limb development
    • Geduspan, J. S. and MacCabe, J. A. (1989). Transfer of dorsoventral information from mesoderm to ectoderm at the onset of limb development. Anal. Rec. 224, 79-87.
    • (1989) Anal. Rec. , vol.224 , pp. 79-87
    • Geduspan, J.S.1    MacCabe, J.A.2
  • 23
    • 0026537348 scopus 로고
    • A growth-promoting influence from the mesonephros during limb outgrowth
    • Geduspan, J. S. and Solursh, M. (1992), A growth-promoting influence from the mesonephros during limb outgrowth. Dev. Biol. 151, 212-250.
    • (1992) Dev. Biol. , vol.151 , pp. 212-250
    • Geduspan, J.S.1    Solursh, M.2
  • 24
    • 84924926133 scopus 로고
    • A series of normal stages in the development of the chick emhyros
    • Hamburger, V. and Hamilton, H. (1951). A series of normal stages in the development of the chick emhyros. J. Morphot. 88, 49-92. Reprinted in Dev. Dynamics 195, 231-272 (1992).
    • (1951) J. Morphot. , vol.88 , pp. 49-92
    • Hamburger, V.1    Hamilton, H.2
  • 25
    • 0027018236 scopus 로고
    • Hamburger, V. and Hamilton, H. (1951). A series of normal stages in the development of the chick emhyros. J. Morphot. 88, 49-92. Reprinted in Dev. Dynamics 195, 231-272 (1992).
    • (1992) Dev. Dynamics , vol.195 , pp. 231-272
  • 27
    • 0027996964 scopus 로고
    • Molecular cloning and expression of bone morphogenetic protein-7 in the chick epiphyseal growth plate
    • Houston, B., Thorp, B. H. and Burt, D. W. (1994). Molecular cloning and expression of bone morphogenetic protein-7 in the chick epiphyseal growth plate. J. Mol. Endocrin. 13, 289-301.
    • (1994) J. Mol. Endocrin. , vol.13 , pp. 289-301
    • Houston, B.1    Thorp, B.H.2    Burt, D.W.3
  • 28
    • 0026427261 scopus 로고
    • Expression of the homeobox Hox-4 genes and the specification of position in chick wing development
    • Izpisúa-Belmonte, J.-C., Tickle, C., Dollé, P., Wolpert. L. and Duboule, D. (1991). Expression of the homeobox Hox-4 genes and the specification of position in chick wing development. Nature 350, 585-589.
    • (1991) Nature , vol.350 , pp. 585-589
    • Izpisúa-Belmonte, J.-C.1    Tickle, C.2    Dollé, P.3    Wolpert, L.4    Duboule, D.5
  • 29
    • 0026753812 scopus 로고
    • Homeobox genes and pattern formation in the vertebrate limb
    • Izpisúa-Belmonte, J.-C. and Duboule, D. (1992). Homeobox genes and pattern formation in the vertebrate limb. Dev. Biol. 152, 26-36.
    • (1992) Dev. Biol. , vol.152 , pp. 26-36
    • Izpisúa-Belmonte, J.-C.1    Duboule, D.2
  • 31
    • 0028569704 scopus 로고
    • Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud
    • Laufer, E., Nelson, C. E., Johnson, R. I., Morgan, B. A. and Tabin, C. (1994). Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.
    • (1994) Cell , vol.79 , pp. 993-1003
    • Laufer, E.1    Nelson, C.E.2    Johnson, R.I.3    Morgan, B.A.4    Tabin, C.5
  • 32
    • 0027054925 scopus 로고
    • Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions
    • Logan, C., Hanks, M., Noble-Topham, S., Nallainathan, D., Provart, N. and Joyner, A. (1992). Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions. Dev. Genet. 13, 345-358.
    • (1992) Dev. Genet. , vol.13 , pp. 345-358
    • Logan, C.1    Hanks, M.2    Noble-Topham, S.3    Nallainathan, D.4    Provart, N.5    Joyner, A.6
  • 34
    • 0029328583 scopus 로고
    • Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage
    • López-Martinez, A., Chang, D. T., Chiang, C., Porter, J. A., Ros, M. A., Simandl, B. K., Beachy, P. A. and Kallon. J. F. (1995). Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage. Curr. Biol. 5, 791-796.
    • (1995) Curr. Biol. , vol.5 , pp. 791-796
    • López-Martinez, A.1    Chang, D.T.2    Chiang, C.3    Porter, J.A.4    Ros, M.A.5    Simandl, B.K.6    Beachy, P.A.7    Kallon, J.F.8
  • 36
    • 0028962789 scopus 로고
    • Why thumbs are up. News and Views
    • Martin, G. R. (1995). Why thumbs are up. News and Views. Nature 374, 410-411.
    • (1995) Nature , vol.374 , pp. 410-411
    • Martin, G.R.1
  • 37
    • 0020642725 scopus 로고
    • A boundary model for pattern formation in vertebrate limbs
    • Meinhardt, H. (1983a). A boundary model for pattern formation in vertebrate limbs. J. Embryol. Exp. Morph. 76, 115-137.
    • (1983) J. Embryol. Exp. Morph. , vol.76 , pp. 115-137
    • Meinhardt, H.1
  • 38
    • 0020743875 scopus 로고
    • Cell determination boundaries as organizing regions for secondary embryonic fields
    • Meinhardt, H. (1983b). Cell determination boundaries as organizing regions for secondary embryonic fields. Dev. Biol. 96, 375-385.
    • (1983) Dev. Biol. , vol.96 , pp. 375-385
    • Meinhardt, H.1
  • 40
    • 0001311398 scopus 로고
    • In situ hybridization analysis of chick embryos in whole mount and tissue sections
    • ed. M. Bronner-Fraser, San Diego: Academic Press
    • Nieto, M. A., Patel, K. and Wilkinson, D. G. (1995). In situ hybridization analysis of chick embryos in whole mount and tissue sections. In Methods in Avian Embryology, (ed. M. Bronner-Fraser), San Diego: Academic Press.
    • (1995) Methods in Avian Embryology
    • Nieto, M.A.1    Patel, K.2    Wilkinson, D.G.3
  • 41
    • 0027436330 scopus 로고
    • FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb
    • Niswander, L., Tickle, C., Vogel, A., Booth, I. and Martin, G. R. (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587.
    • (1993) Cell , vol.75 , pp. 579-587
    • Niswander, L.1    Tickle, C.2    Vogel, A.3    Booth, I.4    Martin, G.R.5
  • 42
    • 0028149891 scopus 로고
    • Signaling in vertebrate limb development: A positive feedback loop between sonichedgehog and FGF4
    • Niswander, L., Jeffrey, S., Martin, G. and Tickle, C. (1994). Signaling in vertebrate limb development: a positive feedback loop between sonichedgehog and FGF4. Nature 371, 609-612.
    • (1994) Nature , vol.371 , pp. 609-612
    • Niswander, L.1    Jeffrey, S.2    Martin, G.3    Tickle, C.4
  • 44
    • 0028951117 scopus 로고
    • Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb
    • Parr, B. A. and McMahon, A. P. (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374, 350-353.
    • (1995) Nature , vol.374 , pp. 350-353
    • Parr, B.A.1    McMahon, A.P.2
  • 46
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C. (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75,1401-1416.
    • (1993) Cell , vol.75 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 47
    • 0028848301 scopus 로고
    • Induction of the LIM homeobox gene Lmx 1 by Wnt7a establishes dorsoventral pattern in the vertebrate limb
    • Riddle, R. D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T. M. and Tabin, C. (1995). Induction of the LIM homeobox gene Lmx 1 by Wnt7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640.
    • (1995) Cell , vol.83 , pp. 631-640
    • Riddle, R.D.1    Ensini, M.2    Nelson, C.3    Tsuchida, T.4    Jessell, T.M.5    Tabin, C.6
  • 48
    • 0026267740 scopus 로고
    • The apical eclodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds
    • Robert, B., Lyons, G., Simandl, B. K., Kuroiwa, A. and Buckingham, M. (1991). The apical eclodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes Dev. 5, 2363-2374.
    • (1991) Genes Dev. , vol.5 , pp. 2363-2374
    • Robert, B.1    Lyons, G.2    Simandl, B.K.3    Kuroiwa, A.4    Buckingham, M.5
  • 49
    • 0029790405 scopus 로고    scopus 로고
    • The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions
    • Ros, M. A., López-Martínez, A., Simandl, B. K., Rodriguez, C., Izpisúa-Belmonte, J.-C, Dahn, R. and Fallen, J. F. (1996). The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. Development 122, 2319-2330.
    • (1996) Development , vol.122 , pp. 2319-2330
    • Ros, M.A.1    López-Martínez, A.2    Simandl, B.K.3    Rodriguez, C.4    Belmonte, J.-C.5    Dahn, R.6    Fallen, J.F.7
  • 50
    • 0020118107 scopus 로고
    • The proximodistal determination of skeletal parts in the developing chick leg
    • Rowe, D. A. and Fallon, J. F. (1982). The proximodistal determination of skeletal parts in the developing chick leg. J. Embryol. Exp. Morph. 68, 1 -7.
    • (1982) J. Embryol. Exp. Morph. , vol.68 , pp. 1-7
    • Rowe, D.A.1    Fallon, J.F.2
  • 51
    • 84924843883 scopus 로고
    • The proximo-distal sequence of the origin of the parts of the chick wing and the role of the ectoderm
    • Saunders, J. W., Jr. (1948). The proximo-distal sequence of the origin of the parts of the chick wing and the role of the ectoderm. J. Exp. Zool. 108, 363-403.
    • (1948) J. Exp. Zool. , vol.108 , pp. 363-403
    • Saunders Jr., J.W.1
  • 52
    • 0016166304 scopus 로고
    • Inductive and axial properties of prospective wing-bud mesoderm in the chick embryo
    • Saunders, J. W. J. and Reuss, C. (1974). Inductive and axial properties of prospective wing-bud mesoderm in the chick embryo. Dev. Biol. 38, 41-50.
    • (1974) Dev. Biol. , vol.38 , pp. 41-50
    • Saunders, J.W.J.1    Reuss, C.2
  • 53
    • 0342381832 scopus 로고
    • Regeneration of the apical ectodermal ridge of the chick limb bud
    • Searls, R. L. and Zwilling, E. (1964). Regeneration of the apical ectodermal ridge of the chick limb bud. Dev. Biol. 9, 38-55.
    • (1964) Dev. Biol. , vol.9 , pp. 38-55
    • Searls, R.L.1    Zwilling, E.2
  • 54
    • 0015012597 scopus 로고
    • The initiation of limb bud outgrowth in the embryonic chick
    • Searls, R. L. and Janners, M. Y. (1971 ). The initiation of limb bud outgrowth in the embryonic chick. Dev. Biol. 24, 198-213.
    • (1971) Dev. Biol. , vol.24 , pp. 198-213
    • Searls, R.L.1    Janners, M.Y.2
  • 55
    • 0019390408 scopus 로고
    • Evidence for a metameric pattern in the development of the chick humerus
    • Stephens, T. D. and McNulty, T. R. (1981 ). Evidence for a metameric pattern in the development of the chick humerus. J. Emhryol. Exp. Morph. 61, 191-205.
    • (1981) J. Emhryol. Exp. Morph. , vol.61 , pp. 191-205
    • Stephens, T.D.1    McNulty, T.R.2
  • 56
    • 0020622206 scopus 로고
    • Peripheral nerves do not play a trophic role in limb skeletal morphogenesis
    • Strecker, T. R. and Stephens, T. D. (1983). Peripheral nerves do not play a trophic role in limb skeletal morphogenesis. Teratology 27, 159-167.
    • (1983) Teratology , vol.27 , pp. 159-167
    • Strecker, T.R.1    Stephens, T.D.2
  • 57
    • 0016309037 scopus 로고
    • A quantitative analysis of the effect of excision of the AER from the chick limb bud
    • Summerbell, D. (1974). A quantitative analysis of the effect of excision of the AER from the chick limb bud. J. Emhryol. Exp. Morph. 32, 651-660.
    • (1974) J. Emhryol. Exp. Morph. , vol.32 , pp. 651-660
    • Summerbell, D.1
  • 58
    • 0015803611 scopus 로고
    • Positional information in chick limb morphogenesis
    • Summerbell, D., Lewis, J. H. and Wolpert, L. (1973) Positional information in chick limb morphogenesis. Nature 224, 492-496.
    • (1973) Nature , vol.224 , pp. 492-496
    • Summerbell, D.1    Lewis, J.H.2    Wolpert, L.3
  • 60
    • 0021289206 scopus 로고
    • Development of the apical ectodermal ridge in the chick wing bud
    • Todt, W. L. and Fallon, J. F. (1984). Development of the apical ectodermal ridge in the chick wing bud. J. Emhryol. Exp. Morph. 80, 21-41.
    • (1984) J. Emhryol. Exp. Morph. , vol.80 , pp. 21-41
    • Todt, W.L.1    Fallon, J.F.2
  • 61
    • 0027165874 scopus 로고
    • FGF-4 maintains polarizing activity of posterior limb bud cells in vivo and in vitro
    • Vogel, A. and Tickle, C. (1993). FGF-4 maintains polarizing activity of posterior limb bud cells in vivo and in vitro. Development 119, 199-206.
    • (1993) Development , vol.119 , pp. 199-206
    • Vogel, A.1    Tickle, C.2
  • 62
    • 0029563650 scopus 로고
    • Dorsal cell fate specified by chick Lmxl during vertebrate limb development
    • Vogel, A., Rodriguez, C., Warnken, W. and Izpisúa-Belmonte, J.-C. (1995).Dorsal cell fate specified by chick Lmxl during vertebrate limb development. Nature 378, 716-720.
    • (1995) Nature , vol.378 , pp. 716-720
    • Vogel, A.1    Rodriguez, C.2    Warnken, W.3    Izpisúa-Belmonte, J.-C.4
  • 63
    • 0029944234 scopus 로고    scopus 로고
    • Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb
    • Vogel, A., Rodriguez, C. and Izpisua-Belmonte, J.-C. (1996). Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122, 1737-1750.
    • (1996) Development , vol.122 , pp. 1737-1750
    • Vogel, A.1    Rodriguez, C.2    Izpisua-Belmonte, J.-C.3
  • 64
    • 0028930947 scopus 로고
    • Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: Dorsal signals regulate anteroposterior patterning
    • Yang, Y. and Niswander, L. (1995). Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell 80, 939-947.
    • (1995) Cell , vol.80 , pp. 939-947
    • Yang, Y.1    Niswander, L.2
  • 65
    • 0025947972 scopus 로고
    • Chicken homeobox gene Msx-1: Structure, expression in limb buds and effect of retinoic acid
    • Yokouchi, Y., Ohsugi, K., Sasaki, H. and Kuroiwa, A. (1991). Chicken homeobox gene Msx-1: structure, expression in limb buds and effect of retinoic acid. Development 113, 431-444.
    • (1991) Development , vol.113 , pp. 431-444
    • Yokouchi, Y.1    Ohsugi, K.2    Sasaki, H.3    Kuroiwa, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.