Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb

Nature

Volumn 386, Issue 6623, 1997, Pages 360-366

  Rodriguez Esteban, Concepción ^a   Schwabe, John W R ^a   De La Peña, Jennifer ^a   Foys, Bryon ^a   Eshelman, Brian ^a   Izpisúa Belmonte, Juan Carlos ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHICK EMBRYO; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EVOLUTION; GENE EXPRESSION REGULATION; LIMB DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AVIAN PROTEINS; BODY PATTERNING; CHICK EMBRYO; CLONING, MOLECULAR; DROSOPHILA; DROSOPHILA PROTEINS; ECTODERM; EMBRYONIC INDUCTION; EVOLUTION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOSYLTRANSFERASES; GLYCOSYLTRANSFERASES; HOMEODOMAIN PROTEINS; INSECT PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIMB BUD; MOLECULAR SEQUENCE DATA; N-ACETYLGLUCOSAMINYLTRANSFERASES; PHENOTYPE; PROTEINS; PROTO-ONCOGENE PROTEINS; RETROVIRIDAE; SEQUENCE HOMOLOGY, NUCLEIC ACID; SIGNAL TRANSDUCTION; WING; WNT PROTEINS;

EID: 0030953531     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/386360a0     Document Type: Article

References (51)

1. Saunders, J. W. & Gasseling, M. T. in Epithelial-Mesenchymal Interactions (eds Fleischmajer, R. & Billingham, R. E.) 78-97 (Baltimore, 1968).
2. Tickle, C., Summerbell, D. & Wolpert, L. Positional signalling and specification of digits in chick limb morphogenesis. Nature 254, 199-202 (1975).
3. Pautou, M. P. & Kieny, M. Interaction ec-mesodermique dans l'establissement de la polarité dorso-ventrale du pied de l'embryon de poulet. C. r. hebd Séanc. Acad. Sci., Paris D 277, 1225-1228 (1973).
4. MacCabe, J. A., Errick, J. E. & Saunders, J. W. J. Ectodermal control of the dorso-ventral axis in the leg bud of the chick embryo. Dev. Biol. 39, 69-82 (1974).
5. Saunders, J. W. J. The proximo-distal sequence of the origin of the parts of the chick wing and the role of the ectoderm. J. Exp. Zool. 108, 363-404 (1948).
6. Todt, W. & Fallon, J. F. Development of the apical ectodermal ridge in the chick wing bud. J. Embryol. Exp. Morphol. 80, 21-41 (1984).
7. Duboule, D. How to make a limb? Science 266, 575-576 (1994).
8. Maden, M. The limb bud - part two. Nature 371, 560-561 (1994).
9. Martin, G. Why thumbs are up. Nature 374, 410-411 (1995).
10. Tabin, C. The initiation of the limb bud: Growth factors, Hox genes, and retinoids. Cell 80, 671-674 (1995).
11. Parr, B. A. & McMahon, A. P. Dorsalizing signal Wnt-7a required for normal polarity of D-Vand A-P axes of mouse limb. Nature 374, 350-353 (1995).
12. Yang, Y. Z. & Niswander, L. Interaction between the signaling molecules Wnt7a and shh during vertebrate limb development-dorsal signals regulated anteroposterior patterning. Cell 80, 939-947 (1995).
13. Riddle, R. et al. Induction of the LIM Homeobox gene Lmx-1 by Wnt7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640 (1995).
14. Vogel, A., Rodriguex, C., Warnken, W. & Izpisúa Belmonte, J. C. Dotsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 378, 716-720 (1995).
15. Loomis, C. A. et al. The mouse Engrailed-1 gene and ventral limb patterning. Nature 382, 360-363 (1996).
16. Niswander, L., Tickle, C., Vogel, A., Booth, I. & Martin, G. R. FGF-4-replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 73, 579-587 (1993).
17. Niswander, L., Jeffrey, S., Martin, G. R. & Tickle, C. A. A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612 (1994).
18. Fallon, J. F. et al. FGF-2: Apical ectodermal ridge growth signal for chick limb development. Science 264, 104-107 (1994).
19. Ohuchi, H. et al. An additional limb can be induced form the flank of the chick embryo by FGF4. Biochem. Biophys. Res. Commun. 209, 809-816 (1995).
20. Cohn, M., Izpisúa Belmonte, J. C., Abud, H., Heath, J. K. & Tickle, C. FGF-2 application can induce additional limb formation from the flank of chick embryos. Cell 80, 739-746 (1995).
21. Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. & Tabin, C. Sonic hedgehog and Fgf-4 act through a signalling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003 (1994).
22. Mahmood, R. et al. A role for FGF8 in the initiation and maintenance of vertebrate limb bud outgrowth. Curr. Biol. 5, 797-806 (1995).
23. Crossley, P. H., Minowada, G., MacArthur, C. A. & Martin, G. R. Roles for FGF-8 in the induction, initiation and maintenance ot chick limb development. Cell 84, 127-136 (1996).
24. Vogel, A., Rodriguez, C. & Izpisúa Belmonte, J. C. Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122, 1737-1750 (1996).
25. Irvine, K. D. & Wieschaus, E. Fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79, 595-606 (1994).
26. Kim, J., Irvine, K. D. & Carroll, S. B. Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802 (1995).
27. Diaz-Benjumea, F. J. & Cohen, S. M. Serrate signals through Notch to establish a Windless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225 (1995).
28. Kim, J. et al. Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382, 133-138 (1996).
29. Neumann, C. J. & Cohen, S. M. A hierarchy of cross-regulation involving Notch, wingless, vestigal and cut organizes the dorsal-ventral axis of the Drosophila wing. Development 122, 3477-3485 (1996).
30. De Celis, J. F., Garcia-Bellido, A. & Bray, S. J. Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122, 359-369 (1996).
31. Wu, J. Y., Wen, L., Zhang, W.-J. & Rao, Y. The secreted product of Xenopus gene lunatic fringe, a vertebrate signaling molecule. Science 273, 355-358 (1996).
32. Yuan, Y. P., Schultz, J., Mlodzik, M. & Bork, P. Secreted Fringe-like signalling molecules may be glycosyltransferases. Cell 88, 9-11 (1997).
33. Cope, L. D. et al. Molecular cloning of a gene involved in lipooligosaccharide biosynthesis and virulence expression by Haemophilus influenzae type B. Mol Microbiol. 5, 1113-1124 (1991).
34. Hamburger, V. & Hamilton, H. A series of normal stages in the development of the chick embryo. J. Morphol. 88, 49-92 (1951).
35. Ros, M. A. et al. The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. Development 122, 2319-2330 (1996).
36. Laufer, E. et al. Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation. Nature 386, 366-373 (1997).
37. Couso, J. P., Kust, E. & Martinez Arias, A. Serrate und wingless in Drosophila wing development. Curr. Biol. 5, 1437-1448 (1995).
38. Goodrich, L. V., Johnson, R. L., Milenkovic, L., McMahon, J. A. & Scott, M. P. Conservation of the Hedgehog/patched/signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog. Genes Dev. 10, 301-312 (1996).
39. Riddle, R. D., Johnson, R. L., Laufer, E. & Tabin, C. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416 (1993).
40. Francis, P. H., Richardson, M. K., Brickell, P. M. & Tickle, C. Bone morphogenetic proteins and a signaling pathway that controls pattern in the developing chick limb. Development 120, 209-218 (1994).
41. Mango, V., Scott, M. P., Johnson, R. L., Goodrich, L. V. & Tabin, C. J. Conservation in hedgehog signaling: induction of a chicken patched homolog by sonic hedgehog in the developing limb. Development 122, 1225-1233 (1996).
42. Zecca, M., Basler, K. & Struhl, G. Sequential organizing activities of engrailed hedgehog and decapentaplegic in the Drosophila wing. Development 121, 2265-2278 (1995).
43. Myat, A., Henrique, D., Ish-Horowicz, D. & Lewis, J. A chick homologue of serrate and its relationship with notch and delta homologues during central neurogenesis. Dev. Biol. 174, 233-247 (1996).
44. Shawber, C. J., Boulter, J. & Weinmaster, G. Jagged2: a serrate-like gene expressed during rat embryogenesis. Dev. Biol. 180, 370-376 (1996).
45. Garcia-Bellido, A. How organisms are put together. Eur. Rev. 2, 15-21 (1994).
46. Izpisúa Belmonte, J. C., Falkenstein, H., Dolle, P., Renucci, A. & Duboule, D. Murine genes related to the Drosophila AbdB homeotic gene are sequentially expressed during development of the posterior part of the body. EMBO J. 10, 2279-2289 (1991).
47. Izpisúa Belmonte, J. C., De Robertis, E. M., Storey, K. G. & Stern, C. The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm. Cell 74, 645-659 (1993).
48. Izpisúa Belmonte, J. C., Tickle, C., Dolle, P., Wolpert, L. & Duboule, D. Expression of the homeobox Hox-4 genes and the specification of position in chick wing development. Nature 350, 585-589 (1991).
49. Morgan, B. A., Izpisúa Belmonte, J. C., Duboule, D. & Tabin, C. J. Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations. Nature 358, 236-239 (1992).
50. Hughes, S., Greenhouse, J., Petropoulos, J. & Sutrave, P. Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors. J. Virol. 61, 3004-3012 (1987).
51. Gilbert, S. F. Dev. Biol. (Sinauer, Sunderland, MA, 1995).