메뉴 건너뛰기




Volumn 125, Issue 6, 1998, Pages 1137-1148

Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs

Author keywords

AER; Engrailed 1; Limb development; Lmx1b; Mouse; Wnt7a

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; ECTODERM; ECTOPIC TISSUE; EMBRYO; EMBRYO PATTERN FORMATION; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; LIMB BUD; LIMB DEVELOPMENT; MESENCHYME; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0031919712     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (146)

References (61)
  • 1
    • 0029865439 scopus 로고    scopus 로고
    • The effect of the ectoderm on the dorsoventral pattern of epidermis, muscles and joints in the developing chick leg: A new model
    • Akita, K. (1996). The effect of the ectoderm on the dorsoventral pattern of epidermis, muscles and joints in the developing chick leg: a new model. Anatomv & Embryology 193, 377-386.
    • (1996) Anatomv & Embryology , vol.193 , pp. 377-386
    • Akita, K.1
  • 2
    • 0030725130 scopus 로고    scopus 로고
    • Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb
    • Altabef, M., Clarke, J. D. W. and Tickle, C. (1997). Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb. Development 124, 4547-4556.
    • (1997) Development , vol.124 , pp. 4547-4556
    • Altabef, M.1    Clarke, J.D.W.2    Tickle, C.3
  • 3
    • 0027479055 scopus 로고
    • The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos
    • Bulfone, A., Kim, H. J., Puelles, L., Porteus, M. H., Grippo, J. F. and Rubenstein, J. L. (1993). The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos. Mech. Dev. 40, 129-140.
    • (1993) Mech. Dev. , vol.40 , pp. 129-140
    • Bulfone, A.1    Kim, H.J.2    Puelles, L.3    Porteus, M.H.4    Grippo, J.F.5    Rubenstein, J.L.6
  • 4
    • 0029005575 scopus 로고
    • Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity
    • Chan, D. C., Laufer, E., Tabin, C. and Leder, P. (1995). Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity. Development 121, 1971-1978.
    • (1995) Development , vol.121 , pp. 1971-1978
    • Chan, D.C.1    Laufer, E.2    Tabin, C.3    Leder, P.4
  • 5
    • 0028959288 scopus 로고
    • The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
    • Crossley, P. H. and Martin, G. R. (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.
    • (1995) Development , vol.121 , pp. 439-451
    • Crossley, P.H.1    Martin, G.R.2
  • 6
    • 0030034731 scopus 로고    scopus 로고
    • Roles for FGF8 in the induction, initiation, and maintenance of chick limb development
    • Crossley, P. H., Minowada, G., MacArthur, C. A. and Martin, G. R. (1996). Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84, 127-136.
    • (1996) Cell , vol.84 , pp. 127-136
    • Crossley, P.H.1    Minowada, G.2    MacArthur, C.A.3    Martin, G.R.4
  • 7
    • 0031454063 scopus 로고    scopus 로고
    • Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants
    • Cygan, J. A., Johnson, R. L. and McMahon, A. P. (1997). Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development 124, 5021-5032.
    • (1997) Development , vol.124 , pp. 5021-5032
    • Cygan, J.A.1    Johnson, R.L.2    McMahon, A.P.3
  • 8
    • 0026101890 scopus 로고
    • Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum
    • Davis, C. A., Holmyard, D. P., Millen, K. J. and Joyner, A. L. (1991). Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development 111, 287-298.
    • (1991) Development , vol.111 , pp. 287-298
    • Davis, C.A.1    Holmyard, D.P.2    Millen, K.J.3    Joyner, A.L.4
  • 9
    • 0026653410 scopus 로고
    • Expression patterns of engrailed-like proteins in the chick embryo
    • Gardner, C. A. and Barald, K. F. (1992). Expression patterns of engrailed-like proteins in the chick embryo. Dev. Dynamics 193, 370-388.
    • (1992) Dev. Dynamics , vol.193 , pp. 370-388
    • Gardner, C.A.1    Barald, K.F.2
  • 10
    • 0023490460 scopus 로고
    • The ectodermal control of mesodermal patterns of differentiation in the developing chick wing
    • Geduspan, J. S. and MacCabe, J. A. (1987). The ectodermal control of mesodermal patterns of differentiation in the developing chick wing. Dev. Biol. 124, 398-408.
    • (1987) Dev. Biol. , vol.124 , pp. 398-408
    • Geduspan, J.S.1    MacCabe, J.A.2
  • 11
    • 0024344580 scopus 로고
    • Transfer of dorsoventral information from mesoderm to ectoderm at the onset of limb development
    • Geduspan, J. S. and MacCabe, J. A. (1989). Transfer of dorsoventral information from mesoderm to ectoderm at the onset of limb development. Anatomical Record 224, 79-87.
    • (1989) Anatomical Record , vol.224 , pp. 79-87
    • Geduspan, J.S.1    MacCabe, J.A.2
  • 12
    • 0030477866 scopus 로고    scopus 로고
    • The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: Implications for the mechanism of apical ridge formation
    • Grieshammer, U., Minowada, G., Pisenti, J. M., Abbott, U. K. and Martin, G. R. (1996). The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: implications for the mechanism of apical ridge formation. Development 122, 3851-3861.
    • (1996) Development , vol.122 , pp. 3851-3861
    • Grieshammer, U.1    Minowada, G.2    Pisenti, J.M.3    Abbott, U.K.4    Martin, G.R.5
  • 13
    • 0029059790 scopus 로고
    • Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
    • Hanks, M., Wurst, W., Anson-Cartwright, L., Auerbach, A. B. and Joyner, A. L. (1995). Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2 [see comments]. Science 269, 679-682.
    • (1995) Science , vol.269 , pp. 679-682
    • Hanks, M.1    Wurst, W.2    Anson-Cartwright, L.3    Auerbach, A.B.4    Joyner, A.L.5
  • 14
    • 0029589439 scopus 로고
    • The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5′ HoxD genes during limb pattern formation
    • Haramis, A. G., Brown, J. M. and Zeller, R. (1995). The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5′ HoxD genes during limb pattern formation. Development 121, 4237-4245.
    • (1995) Development , vol.121 , pp. 4237-4245
    • Haramis, A.G.1    Brown, J.M.2    Zeller, R.3
  • 16
    • 0001698807 scopus 로고
    • Ultrastructural aspects of early development of the forelimb buds in the chick and the mouse
    • Jurand, A. (1965). Ultrastructural aspects of early development of the forelimb buds in the chick and the mouse. Proc. Royal Soc. 162, 387-405.
    • (1965) Proc. Royal Soc. , vol.162 , pp. 387-405
    • Jurand, A.1
  • 17
    • 0020670744 scopus 로고
    • A freeze-fracture and morphometric analysis of gap junctions of limb bud cells: Initial studies on a possible mechanism for morphogenetic signalling during development
    • Kelley, R. O. and Fallon, J. F. (1983). A freeze-fracture and morphometric analysis of gap junctions of limb bud cells: initial studies on a possible mechanism for morphogenetic signalling during development. Progress in Clinical & Biological Research 110, 119-130.
    • (1983) Progress in Clinical & Biological Research , vol.110 , pp. 119-130
    • Kelley, R.O.1    Fallon, J.F.2
  • 18
    • 0030907433 scopus 로고    scopus 로고
    • Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation
    • Laufer, E., Dahn, R., Orozco, O. E., Yeo, C. Y., Pisenti, J., Henrique, D., Abbott, U. K., Fallon, J. F. and Tabin, C. (1997). Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation [see comments]. Nature 386, 366-373.
    • (1997) Nature , vol.386 , pp. 366-373
    • Laufer, E.1    Dahn, R.2    Orozco, O.E.3    Yeo, C.Y.4    Pisenti, J.5    Henrique, D.6    Abbott, U.K.7    Fallon, J.F.8    Tabin, C.9
  • 19
    • 0028569704 scopus 로고
    • Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud
    • Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. and Tabin, C. (1994). Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.
    • (1994) Cell , vol.79 , pp. 993-1003
    • Laufer, E.1    Nelson, C.E.2    Johnson, R.L.3    Morgan, B.A.4    Tabin, C.5
  • 20
    • 0028950732 scopus 로고
    • Jagged: A mammalian ligand that activates Notch 1
    • Lindsell, C. E., Shawber, C. J., Boulter, J. and Weinmaster, G. (1995). Jagged: a mammalian ligand that activates Notch 1. Cell 80, 909-917.
    • (1995) Cell , vol.80 , pp. 909-917
    • Lindsell, C.E.1    Shawber, C.J.2    Boulter, J.3    Weinmaster, G.4
  • 21
    • 0030855266 scopus 로고    scopus 로고
    • The role of Engrailed in establishing the dorsoventral axis of the chick limb
    • Logan, C., Hornbruch, A., Campbell, I. and Lumsden, A. (1997). The role of Engrailed in establishing the dorsoventral axis of the chick limb. Development 124, 2317-2324.
    • (1997) Development , vol.124 , pp. 2317-2324
    • Logan, C.1    Hornbruch, A.2    Campbell, I.3    Lumsden, A.4
  • 23
    • 0024991197 scopus 로고
    • Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A)
    • Lyons, K. M., Pelton, R. W. and Hogan, B. L. (1990). Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 109, 833-844.
    • (1990) Development , vol.109 , pp. 833-844
    • Lyons, K.M.1    Pelton, R.W.2    Hogan, B.L.3
  • 24
    • 0016197076 scopus 로고
    • Ectodermal control of the dorsoventral axis in the leg bud of the chick embryo
    • MacCabe, J. A., Errick, J. and Saunders, J. W., Jr. (1974). Ectodermal control of the dorsoventral axis in the leg bud of the chick embryo. Dev. Biol. 39, 69-82.
    • (1974) Dev. Biol. , vol.39 , pp. 69-82
    • MacCabe, J.A.1    Errick, J.2    Saunders Jr., J.W.3
  • 25
    • 0029328540 scopus 로고
    • A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth
    • Mahmood, R., et al. (1995). A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth. Current Biology 5, 797-806.
    • (1995) Current Biology , vol.5 , pp. 797-806
    • Mahmood, R.1
  • 26
    • 0028962789 scopus 로고
    • Why thumbs are up
    • Martin, G. R. (1995). Why thumbs are up. Nature 374, 410-411.
    • (1995) Nature , vol.374 , pp. 410-411
    • Martin, G.R.1
  • 27
    • 0030774912 scopus 로고    scopus 로고
    • Expression patterns of developmental control genes in normal and Engrailed-1 mutant mouse spinal cord reveal early diversity in developing interneurons
    • Matise, M. P. and Joyner, A. L. (1997). Expression patterns of developmental control genes in normal and Engrailed-1 mutant mouse spinal cord reveal early diversity in developing interneurons. J. Neurosci. 17, 7805-7816.
    • (1997) J. Neurosci. , vol.17 , pp. 7805-7816
    • Matise, M.P.1    Joyner, A.L.2
  • 28
    • 0020743875 scopus 로고
    • Cell determination boundaries as organizing regions for secondary embryonic fields
    • Meinhardt, H. (1983). Cell determination boundaries as organizing regions for secondary embryonic fields. Dev. Biol. 96, 375-385.
    • (1983) Dev. Biol. , vol.96 , pp. 375-385
    • Meinhardt, H.1
  • 29
    • 0030982018 scopus 로고    scopus 로고
    • The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure
    • Michaud, J. L., Lapointe, F. and Le Douarin, N. M. (1997). The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure. Development 124, 1453-1463.
    • (1997) Development , vol.124 , pp. 1453-1463
    • Michaud, J.L.1    Lapointe, F.2    Le Douarin, N.M.3
  • 30
    • 0242549754 scopus 로고
    • Histochemical aspects of organogenesis in vertrebrates. Part I. The skeletal system. Limb morphogenesis. The sense organs
    • Stuttgart: Gustav Fischer Verlag
    • Milaire, J. (1974). Histochemical aspects of organogenesis in vertrebrates. Part I. The skeletal system. Limb morphogenesis. The sense organs. In Handbuch der Histochemie pp. 38-60., Stuttgart: Gustav Fischer Verlag.
    • (1974) Handbuch der Histochemie , pp. 38-60
    • Milaire, J.1
  • 31
    • 0028988980 scopus 로고
    • A Xenopus distalless gene in transgenic mice: Conserved regulation in distal limb epidermis and other sites of epithelial-mesenchymal interaction
    • Morasso, M. I., Mahon, K. A. and Sargent, T. D. (1995). A Xenopus distalless gene in transgenic mice: conserved regulation in distal limb epidermis and other sites of epithelial-mesenchymal interaction. Proc. Natl. Acad. Sci. USA 92, 3968-3972.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3968-3972
    • Morasso, M.I.1    Mahon, K.A.2    Sargent, T.D.3
  • 32
    • 0029743225 scopus 로고    scopus 로고
    • Growth factor interactions in limb development
    • Niswander, L. (1996). Growth factor interactions in limb development. Ann. N.Y. Acad. Sci. 785, 23-26.
    • (1996) Ann. N.Y. Acad. Sci. , vol.785 , pp. 23-26
    • Niswander, L.1
  • 33
    • 0028149891 scopus 로고
    • A positive feedback loop coordinates growth and patterning in the vertebrate limb
    • Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C. (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb [see comments]. Nature 371, 609-612.
    • (1994) Nature , vol.371 , pp. 609-612
    • Niswander, L.1    Jeffrey, S.2    Martin, G.R.3    Tickle, C.4
  • 34
    • 0026532352 scopus 로고
    • Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse
    • Niswander, L. and Martin, G. R. (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.
    • (1992) Development , vol.114 , pp. 755-768
    • Niswander, L.1    Martin, G.R.2
  • 35
    • 0027227968 scopus 로고
    • FGF-4 regulates expression of Evx-1 in the developing mouse limb
    • Niswander, L. and Martin, G. R. (1993). FGF-4 regulates expression of Evx-1 in the developing mouse limb. Development 119, 287-294.
    • (1993) Development , vol.119 , pp. 287-294
    • Niswander, L.1    Martin, G.R.2
  • 36
    • 0027436330 scopus 로고
    • FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb
    • Niswander, L., Tickle, C., Vogel, A., Booth, I. and Martin, G. R. (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587.
    • (1993) Cell , vol.75 , pp. 579-587
    • Niswander, L.1    Tickle, C.2    Vogel, A.3    Booth, I.4    Martin, G.R.5
  • 38
    • 0030297469 scopus 로고    scopus 로고
    • Gene expression in the limbless mutant: Polarized gene expression in the absence of Shh and an AER
    • Noramly, S., Pisenti, J., Abbott, U. and Morgan, B. (1996). Gene expression in the limbless mutant: polarized gene expression in the absence of Shh and an AER. Dev. Biol. 179, 339-346.
    • (1996) Dev. Biol. , vol.179 , pp. 339-346
    • Noramly, S.1    Pisenti, J.2    Abbott, U.3    Morgan, B.4
  • 39
    • 17544386960 scopus 로고    scopus 로고
    • A chick wingless mutation causes abnormality in maintenance of Fgf8 expression in the wing apical ridge, resulting in loss of the dorsoventral boundary
    • Ohuchi, H., Shibusawa, M., Nakagawa, T., Ohata, T., Yoshioka, H., Hirai, Y., Nohno, T., Noji, S. and Kondo, N. (1997). A chick wingless mutation causes abnormality in maintenance of Fgf8 expression in the wing apical ridge, resulting in loss of the dorsoventral boundary. Mech. Dev. 62, 3-13.
    • (1997) Mech. Dev. , vol.62 , pp. 3-13
    • Ohuchi, H.1    Shibusawa, M.2    Nakagawa, T.3    Ohata, T.4    Yoshioka, H.5    Hirai, Y.6    Nohno, T.7    Noji, S.8    Kondo, N.9
  • 40
    • 0028126669 scopus 로고
    • Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis
    • Ohuchi, H., Yoshioka, H., Tanaka, A., Kawakami, Y., Nohno, T. and Noji, S. (1994). Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis. Biochem. Biophys. Res. Comm. 204, 882-888.
    • (1994) Biochem. Biophys. Res. Comm. , vol.204 , pp. 882-888
    • Ohuchi, H.1    Yoshioka, H.2    Tanaka, A.3    Kawakami, Y.4    Nohno, T.5    Noji, S.6
  • 41
    • 0028951117 scopus 로고
    • Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb
    • Parr, B. A. and McMahon, A. P. (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374, 350-353.
    • (1995) Nature , vol.374 , pp. 350-353
    • Parr, B.A.1    McMahon, A.P.2
  • 42
    • 0027201903 scopus 로고
    • Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds
    • Parr, B. A., Shea, M. J., Vassileva, G. and McMahon, A. P. (1993). Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119, 247-261.
    • (1993) Development , vol.119 , pp. 247-261
    • Parr, B.A.1    Shea, M.J.2    Vassileva, G.3    McMahon, A.P.4
  • 43
    • 0142170113 scopus 로고
    • ed. Ede, D. A., Hinchliffe, J. R. and Balls, M., Cambridge: Cambridge University Press
    • Pautau, M. P. (1977). Vertebrate Limb and Somite Morphogenesis (ed. Ede, D. A., Hinchliffe, J. R. and Balls, M.) Cambridge: Cambridge University Press.
    • (1977) Vertebrate Limb and Somite Morphogenesis
    • Pautau, M.P.1
  • 44
    • 0011313349 scopus 로고
    • Interaction ec-mesodermique dans l'etablissement de la polarite dorso-ventrale du pied de l'embryon de poulet. C.r. hebd Seanc
    • Pautou, M. P. and Kieny, M. (1973). Interaction ec-mesodermique dans l'etablissement de la polarite dorso-ventrale du pied de l'embryon de poulet. C.r. hebd Seanc. Acad. Sci., Paris D277.
    • (1973) Acad. Sci., Paris , vol.D277
    • Pautou, M.P.1    Kieny, M.2
  • 46
    • 0028848301 scopus 로고
    • Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb
    • Riddle, R. D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T. M. and Tabin, C. (1995). Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640.
    • (1995) Cell , vol.83 , pp. 631-640
    • Riddle, R.D.1    Ensini, M.2    Nelson, C.3    Tsuchida, T.4    Jessell, T.M.5    Tabin, C.6
  • 47
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C. (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.
    • (1993) Cell , vol.75 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 48
    • 0028080191 scopus 로고
    • Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distalless homeobox genes in craniofacial development
    • Robinson, G. W. and Mahon, K. A. (1994). Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distalless homeobox genes in craniofacial development. Mech. Dev. 48, 199-215.
    • (1994) Mech. Dev. , vol.48 , pp. 199-215
    • Robinson, G.W.1    Mahon, K.A.2
  • 49
    • 0030953531 scopus 로고    scopus 로고
    • Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb
    • Rodriguez-Esteban, C., Schwabe, J. W., De La Pena, J., Foys, B., Eshelman, B. and Belmonte, J. C. (1997). Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb [see comments]. Nature 386, 360-366.
    • (1997) Nature , vol.386 , pp. 360-366
    • Rodriguez-Esteban, C.1    Schwabe, J.W.2    De La Pena, J.3    Foys, B.4    Eshelman, B.5    Belmonte, J.C.6
  • 50
    • 0029790405 scopus 로고    scopus 로고
    • The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions
    • Ros, M. A., Lopez-Martinez, A., Simandl, B. K., Rodriguez, C., Izpisua Belmonte, J. C., Dahn, R. and Fallon, J. F. (1996). The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. Development 122, 2319-2330.
    • (1996) Development , vol.122 , pp. 2319-2330
    • Ros, M.A.1    Lopez-Martinez, A.2    Simandl, B.K.3    Rodriguez, C.4    Izpisua Belmonte, J.C.5    Dahn, R.6    Fallon, J.F.7
  • 51
    • 84924843883 scopus 로고
    • The proximo-distal sequence of the origin of the parts of the chick wing and the role of th ectoderm
    • Saunders, J. W., Jr. (1948). The proximo-distal sequence of the origin of the parts of the chick wing and the role of th ectoderm. J. Exp. Zool. 108, 363-404.
    • (1948) J. Exp. Zool. , vol.108 , pp. 363-404
    • Saunders Jr., J.W.1
  • 53
    • 0030725263 scopus 로고    scopus 로고
    • Serrate2 is disrupted in the mouse limb-development mutant syndactylism
    • Sidow, A., et al. (1997). Serrate2 is disrupted in the mouse limb-development mutant syndactylism. Nature 389, 722-725.
    • (1997) Nature , vol.389 , pp. 722-725
    • Sidow, A.1
  • 54
    • 0031081037 scopus 로고    scopus 로고
    • Induction of additional limb at the dorsal-ventral boundary of a chick embryo
    • Tanaka, M., Tamura, K., Noji, S., Nohno, T. and Ide, H. (1997). Induction of additional limb at the dorsal-ventral boundary of a chick embryo. Dev. Biol. 182, 191-203.
    • (1997) Dev. Biol. , vol.182 , pp. 191-203
    • Tanaka, M.1    Tamura, K.2    Noji, S.3    Nohno, T.4    Ide, H.5
  • 55
    • 0029100040 scopus 로고
    • Vertebrate limb development
    • Tickle, C. (1995). Vertebrate limb development. Curr. Opin. Genet. Dev. 5, 478-484.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 478-484
    • Tickle, C.1
  • 56
    • 0029944234 scopus 로고    scopus 로고
    • Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb
    • Vogel, A., Rodriguez, C. and Izpisua-Belmonte, J. C. (1996). Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122, 1737-1750.
    • (1996) Development , vol.122 , pp. 1737-1750
    • Vogel, A.1    Rodriguez, C.2    Izpisua-Belmonte, J.C.3
  • 57
    • 0029563650 scopus 로고
    • Dorsal cell fate specified by chick Lmx1 during vertebrate limb development
    • Vogel, A., Rodriguez, C., Warnken, W. and Izpisua Belmonte, J. C. (1995). Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 378, 716-720.
    • (1995) Nature , vol.378 , pp. 716-720
    • Vogel, A.1    Rodriguez, C.2    Warnken, W.3    Izpisua Belmonte, J.C.4
  • 59
    • 0028310311 scopus 로고
    • Multiple developmental defects in Engrailed-1 mutant mice: An early mid-hindbrain deletion and patterning defects in forelimbs and sternum
    • Wurst, W., Auerbach, A. B. and Joyner, A. L. (1994). Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development 120, 2065-2075.
    • (1994) Development , vol.120 , pp. 2065-2075
    • Wurst, W.1    Auerbach, A.B.2    Joyner, A.L.3
  • 60
    • 0028930947 scopus 로고
    • Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: Dorsal signals regulate anteroposterior patterning
    • Yang, Y. and Niswander, L. (1995). Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell 80, 939-947.
    • (1995) Cell , vol.80 , pp. 939-947
    • Yang, Y.1    Niswander, L.2
  • 61
    • 0031194570 scopus 로고    scopus 로고
    • Dorso-ventral limb polarity and origin of the ridge: On the fringe of independence?
    • Zeller, R. and Duboule, D. (1997). Dorso-ventral limb polarity and origin of the ridge: on the fringe of independence? BioEssays 19, 541-546.
    • (1997) BioEssays , vol.19 , pp. 541-546
    • Zeller, R.1    Duboule, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.