Lipid rafts constrain basal α1A-adrenergic receptor signaling by maintaining receptor in an inactive conformation

Cellular Signalling

Volumn 21, Issue 10, 2009, Pages 1532-1539

  Lei, Beilei ^a   Morris, Daniel P ^a   Smith, Michael P ^a   Schwinn, Debra A ^b,c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Adrenergic receptor; GPCR; Lipid rafts; Preassembled receptor G protein complexes; Signal transduction

Indexed keywords

ALPHA 1A ADRENERGIC RECEPTOR; CHOLESTEROL; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; METHYL BETA CYCLODEXTRIN; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST CULTURE; INTERNALIZATION; LIPID RAFT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN INTERACTION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; BETA-CYCLODEXTRINS; FIBROBLASTS; GTP-BINDING PROTEINS; HUMANS; INOSITOL PHOSPHATES; MEMBRANE MICRODOMAINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; SIGNAL TRANSDUCTION;

RATTUS;

EID: 67649236110     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2009.06.001     Document Type: Article

References (55)

1. Pike L.J. J. Lipid. Res. 44 4 (2003) 655
2. Parton R.G., and Simons K. Nat. Rev. Mol. Cell. Biol. 8 3 (2007) 185
3. Insel P.A., Head B.P., Patel H.H., Roth D.M., Bundey R.A., and Swaney J.S. Biochem. Soc. Trans. 33 Pt 5 (2005) 1131
4. Pike L.J., and Casey L. Biochemistry 41 32 (2002) 10315
5. Rybin V.O., Xu X., Lisanti M.P., and Steinberg S.F. J. Biol. Chem. 275 52 (2000) 41447
6. Rudner X.L., Berkowitz D.E., Booth J.V., Funk B.L., Cozart K.L., D'Amico E.B., El-Moalem H., Page S.O., Richardson C.D., Winters B., Marucci L., and Schwinn D.A. Circulation 100 23 (1999) 2336
7. Michelotti G.A., Price D.T., and Schwinn D.A. Pharmacol. Ther. 88 3 (2000) 281
8. Morris D.P., Lei B., Wu Y.X., Michelotti G.A., and Schwinn D.A. J. Biol. Chem. 283 5 (2008) 2973
9. Huang Y., Wright C.D., Merkwan C.L., Baye N.L., Liang Q., Simpson P.C., and O'Connell T.D. Circulation 115 6 (2007) 763
10. Fujita T., Toya Y., Iwatsubo K., Onda T., Kimura K., Umemura S., and Ishikawa Y. Cardiovasc. Res. 51 4 (2001) 709
11. Lanzafame A.A., Turnbull L., Amiramahdi F., Arthur J.F., Huynh H., and Woodcock E.A. Am. J. Physiol, Heart Circ. Physiol. 290 5 (2006) H2059
12. Hein P., and Bunemann M. Naunyn-Schmiedeberg's. Arch. Pharmacol. 379 5 (2009) 435
13. Philip F., Sengupta P., and Scarlata S. J. Biol. Chem. 282 26 (2007) 19203
14. Nobles M., Benians A., and Tinker A. Proc. Natl. Acad. Sci. U. S. A. 102 51 (2005) 18706
15. Lei B., Morris D.P., Smith M.P., Svetkey L.P., Newman M.F., Rotter J.I., Buchanan T.A., Beckstrom-Sternberg S.M., Green E.D., and Schwinn D.A. Naunyn-Schmiedeberg's. Arch. Pharmacol. 371 3 (2005) 229
16. Morris J.B., Huynh H., Vasilevski O., and Woodcock E.A. J. Mol. Cell. Cardiol. 41 1 (2006) 17
17. Cotecchia S. Biochem. Pharmacol. 73 8 (2007) 1076
18. Zidovetzki R., and Levitan I. Biochim. Biophys. Acta 1768 6 (2007) 1311
19. Williams N.G., Zhong H., and Minneman K.P. J. Biol. Chem. 273 38 (1998) 24624
20. Alexandrov A., Keffel S., Goepel M., and Michel M.C. Biochem. Biophys. Res. Commun. 261 2 (1999) 372
21. Lefkowitz R.J., Cotecchia S., Samama P., and Costa T. Trends. Pharmacol. Sci. 14 8 (1993) 303
22. Kobilka B.K., and Deupi X. Trends. Pharmacol. Sci. 28 8 (2007) 397
23. Morris D.P., Price R.R., Smith M.P., Lei B., and Schwinn D.A. Mol. Pharmacol. 66 4 (2004) 843
24. Pediani J.D., Colston J.F., Caldwell D., Milligan G., Daly C.J., and McGrath J.C. Mol. Pharmacol. 67 4 (2005) 992
25. Miura Y., Hanada K., and Jones T.L. Biochemistry 40 50 (2001) 15418
26. Calaghan S., and White E. Cardiovasc. Res. 69 4 (2006) 816
27. Xu W., Yoon S.I., Huang P., Wang Y., Chen C., Chong P.L., and Liu-Chen L.Y. J. Pharmacol. Exp. Ther. 317 3 (2006) 1295
28. Whetton A.D., Gordon L.M., and Houslay M.D. Biochem. J. 210 2 (1983) 437
29. Whetton A.D., Gordon L.M., and Houslay M.D. Biochem. J. 212 2 (1983) 331
30. Xiang Y., Rybin V.O., Steinberg S.F., and Kobilka B. J. Biol. Chem. 277 37 (2002) 34280
31. Pontier S.M., Percherancier Y., Galandrin S., Breit A., Gales C., and Bouvier M. J. Biol. Chem. 283 36 (2008) 24659
32. Oh P., and Schnitzer J.E. Mol. Biol. Cell. 12 3 (2001) 685
33. Chini B., and Parenti M. J. Mol. Endocrinol. 32 2 (2004) 325
34. Clarke C.J., Ohanian V., and Ohanian J. Am. J. Physiol, Heart Circ. Physiol. 292 5 (2007) H2248
35. van Rheenen J., Achame E.M., Janssen H., Calafat J., and Jalink K. Embo. J. 24 9 (2005) 1664
36. Gamper N., and Shapiro M.S. J. Physiol. 582 Pt 3 (2007) 967
37. Sengupta P., Philip F., and Scarlata S. J. Cell Sci. 121 Pt 9 (2008) 1363
38. Abankwa D., and Vogel H. J. Cell Sci. 120 Pt 16 (2007) 2953
39. Vogler O., Barcelo J.M., Ribas C., and Escriba P.V. Biochim. Biophys. Acta 1778 7-8 (2008) 1640
40. Murthy K.S., and Makhlouf G.M. J. Biol. Chem. 275 39 (2000) 30211
41. Tolkovsky A.M., and Levitzki A. Biochemistry 17 18 (1978) 3795
42. Houslay M.D., Dipple I., and Elliott K.R. Biochem. J. 186 3 (1980) 649
43. Oldham W.M., and Hamm H.E. Q. Rev. Biophys. 39 2 (2006) 117
44. Ayoub M.A., Maurel D., Binet V., Fink M., Prezeau L., Ansanay H., and Pin J.P. Mol. Pharmacol. 71 5 (2007) 1329
45. Jensen J.B., Lyssand J.S., Hague C., and Hille B. J. Gen. Physiol. 133 4 (2009) 347
46. Lohse M.J., Hein P., Hoffmann C., Nikolaev V.O., Vilardaga J.P., and Bunemann M. Br. J. Pharmacol. 153 Suppl. 1 (2008) S125
47. Hollins B., Kuravi S., Digby G.J., and Lambert N.A. Cell. Signal. 21 6 (2009) 1015
48. Schwinn D.A., Page S.O., Middleton J.P., Lorenz W., Liggett S.B., Yamamoto K., Lapetina E.G., Caron M.G., Lefkowitz R.J., and Cotecchia S. Mol. Pharmacol. 40 5 (1991) 619
49. Theroux T.L., Esbenshade T.A., Peavy R.D., and Minneman K.P. Mol. Pharmacol. 50 5 (1996) 1376
50. Price R.R., Morris D.P., Biswas G., Smith M.P., and Schwinn D.A. J. Biol. Chem. 277 11 (2002) 9570
51. Qin K., Sethi P.R., and Lambert N.A. FASEB J. 22 8 (2008) 2920
52. Stanasila L., Abuin L., Dey J., and Cotecchia S. Mol. Pharmacol. 74 3 (2008) 562
53. Clerk A., Cullingford T.E., Fuller S.J., Giraldo A., Markou T., Pikkarainen S., and Sugden P.H. J. Cell. Physiol. 212 2 (2007) 311
54. Kjelsberg M.A., Cotecchia S., Ostrowski J., Caron M.G., and Lefkowitz R.J. J. Biol. Chem. 267 3 (1992) 1430
55. Gether U., Ballesteros J.A., Seifert R., Sanders-Bush E., Weinstein H., and Kobilka B.K. J. Biol. Chem. 272 5 (1997) 2587