The α1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits

Journal of Biological Chemistry

Volumn 283, Issue 5, 2008, Pages 2973-2985

  Morris, Daniel P ^a,c   Lei, Beilei ^a   Wu, Yue Xuan ^a   Michelotti, Gregory A ^a   Schwinn, Debra A ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGON; DIFFRACTIVE OPTICAL ELEMENTS; ENERGY TRANSFER; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; MEMBRANES; PLASMAS; SURFACE ANALYSIS;

ADRENERGIC RECEPTORS; BASAL CONDITIONS; CELL SURFACES; CHOLERA TOXINS; CHOLESTEROL DEPLETIONS; CLATHRIN; DENSITY GRADIENTS; FLUORESCENCE RESONANCE ENERGY TRANSFER MEASUREMENTS; G PROTEINS; HETEROLOGOUS EXPRESSION SYSTEMS; LIPID RAFTS; LOW DENSITIES; PHENYLEPHRINE; PLASMA MEMBRANES; RECEPTOR STIMULATIONS; SURFACE RECEPTORS;

CELL MEMBRANES;

ALPHA 1A ADRENERGIC RECEPTOR; CELL RECEPTOR; CHOLERA TOXIN B SUBUNIT; CHOLESTEROL; CLATHRIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HEMAGGLUTININ; METHYL BETA CYCLODEXTRIN; PHENYLEPHRINE; ALPHA 1 ADRENERGIC RECEPTOR; BETA CYCLODEXTRIN DERIVATIVE; CHOLERA TOXIN; HYBRID PROTEIN; METHYL-BETA-CYCLODEXTRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; LIPID MEMBRANE; LIPID RAFT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN LOCALIZATION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL MEMBRANE; COATED PIT; DRUG EFFECT; GENETICS; HUMAN; METABOLISM;

ANIMALS; BETA-CYCLODEXTRINS; CELL LINE; CHOLERA TOXIN; CHOLESTEROL; COATED PITS, CELL-MEMBRANE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GTP-BINDING PROTEINS; HUMANS; MEMBRANE MICRODOMAINS; PHENYLEPHRINE; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 41449117717     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705795200     Document Type: Article

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