Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression

Toxicological Sciences

Volumn 110, Issue 1, 2009, Pages 68-83

  Nesnow, Stephen ^a   Ward, William ^a   Moore, Tanya ^a   Ren, Hongzu ^a   Hester, Susan D ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Conazoles; Human relevance; Phenobarbital; Propiconazole; Transcriptional analyses; Triadimefon; Tumorigenesis

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BCL2 RELATED PROTEIN A1; C REACTIVE PROTEIN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; FARNESOID X RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; PARATHYROID HORMONE RECEPTOR; PHENOBARBITAL; PHOSPHATIDATE PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROPICONAZOLE; PROTEIN BAD; PROTEIN CDC42; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; RETINOBLASTOMA PROTEIN; RETINOID X RECEPTOR; SMAD4 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TERCONAZOLE; TRANSCRIPTION FACTOR E2F3; TRIADIMEFON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GENETIC ASSOCIATION; HISTOPATHOLOGY; LIVER CELL CARCINOMA; LIVER HYPERTROPHY; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; TOXICOGENETICS; TRANSCRIPTION REGULATION;

ANIMALS; CARCINOGENS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL PROLIFERATION; FUNGICIDES, INDUSTRIAL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HYBRIDIZATION, GENETIC; LIVER; MALE; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SIZE; PHENOBARBITAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRIAZOLES;

MUS;

EID: 67649224671     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp076     Document Type: Article

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