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Volumn 72, Issue 7, 1998, Pages 429-438

Formation of 8-oxodeoxyguanosine in brain DNA of rats exposed to acrylonitrile

Author keywords

8 Hydroxydeoxyguanosine; 8 Oxodeoxyguanosine; Epigenetic mechanisms Methylnitrosourea; Oxidative DNA damage

Indexed keywords

ACRYLONITRILE;

EID: 0031811612     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050523     Document Type: Article
Times cited : (43)

References (65)
  • 1
    • 0019406020 scopus 로고
    • Acrylonitrile: In vivo metabolism in rats and mice
    • Ahmed AE, Patel K (1981) Acrylonitrile: In vivo metabolism in rats and mice. Drug Metab Dispos 9: 219-222
    • (1981) Drug Metab Dispos , vol.9 , pp. 219-222
    • Ahmed, A.E.1    Patel, K.2
  • 2
    • 0023434210 scopus 로고
    • An ab initio molecular orbital study on the characteristics of 8-hydroxyguanine
    • Aida M, Nishimura S (1987) An ab initio molecular orbital study on the characteristics of 8-hydroxyguanine. Mutat Res 192: 83-89
    • (1987) Mutat Res , vol.192 , pp. 83-89
    • Aida, M.1    Nishimura, S.2
  • 3
    • 0024460992 scopus 로고
    • Endogenous oxidative DNA damage, aging, and cancer
    • Ames BN (1989) Endogenous oxidative DNA damage, aging, and cancer. Free Radic Res Commun 7: 121-128
    • (1989) Free Radic Res Commun , vol.7 , pp. 121-128
    • Ames, B.N.1
  • 4
    • 0024415434 scopus 로고
    • Glutathione metabolism at the blood-cerebrospinal fluid barrier
    • Anderson ME, Underwood M, Bridges RJ, Meister A (1989) Glutathione metabolism at the blood-cerebrospinal fluid barrier. FASEB J 3: 2527-2531
    • (1989) FASEB J , vol.3 , pp. 2527-2531
    • Anderson, M.E.1    Underwood, M.2    Bridges, R.J.3    Meister, A.4
  • 5
  • 6
    • 41049100518 scopus 로고
    • A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase
    • Beers RF Jr, Sizer IW (1952) A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 195: 133-140
    • (1952) J Biol Chem , vol.195 , pp. 133-140
    • Beers Jr., R.F.1    Sizer, I.W.2
  • 7
    • 0022641697 scopus 로고
    • Primary brain tumors in Fischer 344 rats chronically exposed to acrylonitrile in their drinking water
    • Bigner DD, Bigner SH, Burger PC, Shellburne JD, Friedman HS (1986) Primary brain tumors in Fischer 344 rats chronically exposed to acrylonitrile in their drinking water. Food Chem Toxicol 24: 129-137
    • (1986) Food Chem Toxicol , vol.24 , pp. 129-137
    • Bigner, D.D.1    Bigner, S.H.2    Burger, P.C.3    Shellburne, J.D.4    Friedman, H.S.5
  • 11
    • 0026592966 scopus 로고
    • 8-Hydroxyguanine, an abundant form of oxidative DNa damage, causes G → T and a → C substitutions
    • Cheng KC, Cahill DS, Kasai H, Nishimura S, Loeb LA (1992) 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions. J Biol Chem 267: 166-172
    • (1992) J Biol Chem , vol.267 , pp. 166-172
    • Cheng, K.C.1    Cahill, D.S.2    Kasai, H.3    Nishimura, S.4    Loeb, L.A.5
  • 12
    • 0026735007 scopus 로고
    • Increased 8-oxodeoxyguanosine levels in lung DNa of A J mice and F344 rats treated with the tobacco-specific nitrosamine 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanonc
    • Chung FL, Xu Y (1992) Increased 8-oxodeoxyguanosine levels in lung DNA of A J mice and F344 rats treated with the tobacco-specific nitrosamine 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanonc. Carcinogenesis 13: 1269-1272
    • (1992) Carcinogenesis , vol.13 , pp. 1269-1272
    • Chung, F.L.1    Xu, Y.2
  • 13
    • 0026653104 scopus 로고
    • Pheno sensitization of DNA to subsequent oxidative damage in 8-hydroxyguanine assays
    • Claycamp HG (1992) Pheno sensitization of DNA to subsequent oxidative damage in 8-hydroxyguanine assays. Carcinogenesis 13: 1289-1292
    • (1992) Carcinogenesis , vol.13 , pp. 1289-1292
    • Claycamp, H.G.1
  • 14
    • 0029008428 scopus 로고
    • Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates
    • Commandeur JNM, Stijntjes GJ, Vermeiden NPE (1995) Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Pharmacol Rev 47: 271-330
    • (1995) Pharmacol Rev , vol.47 , pp. 271-330
    • Commandeur, J.N.M.1    Stijntjes, G.J.2    Vermeiden, N.P.E.3
  • 15
    • 0024841281 scopus 로고
    • Structural and conformational analyses of 8-hydroxy-2′~~-deoxyguanosine
    • Culp SJ, Cho BP, Kadlubar FF, Evans FE (1989) Structural and conformational analyses of 8-hydroxy-2′~~-deoxyguanosine. Chem Res Toxicol 2: 416-422
    • (1989) Chem Res Toxicol , vol.2 , pp. 416-422
    • Culp, S.J.1    Cho, B.P.2    Kadlubar, F.F.3    Evans, F.E.4
  • 16
    • 0027497437 scopus 로고
    • N-Nitrosodimethylamine. N-nitrosodiethylamine, and N-nitrosomorpholine fail to generate 8-hydroxy-2′-deoxyguanosine in liver DNA of male F344 rats
    • Dahlnaus M, Appel KE (1993) N-Nitrosodimethylamine. N-nitrosodiethylamine, and N-nitrosomorpholine fail to generate 8-hydroxy-2′-deoxyguanosine in liver DNA of male F344 rats. Mutat Res 285: 295-302
    • (1993) Mutat Res , vol.285 , pp. 295-302
    • Dahlnaus, M.1    Appel, K.E.2
  • 17
    • 0028987060 scopus 로고
    • In vivo accumulation of 8-hydroxy-2′-deoxyguanosine in DNA correlates with release of reactive oxygen species in Fanconi's anaemia families
    • Degan P, Bonassi S, DeCaterina M, Korkina LG, Pinto L, Scopacasa F, Zatterale A, Calzone R, Pagano G (1995) In vivo accumulation of 8-hydroxy-2′-deoxyguanosine in DNA correlates with release of reactive oxygen species in Fanconi's anaemia families. Carcinogenesis 16: 735-742
    • (1995) Carcinogenesis , vol.16 , pp. 735-742
    • Degan, P.1    Bonassi, S.2    DeCaterina, M.3    Korkina, L.G.4    Pinto, L.5    Scopacasa, F.6    Zatterale, A.7    Calzone, R.8    Pagano, G.9
  • 18
    • 0009663357 scopus 로고
    • A multiple comparisons procedure for comparing several treatments with a control
    • Dunnett CW (1955) A multiple comparisons procedure for comparing several treatments with a control. J Am Stat Assoc 50: 1096-1121
    • (1955) J Am Stat Assoc , vol.50 , pp. 1096-1121
    • Dunnett, C.W.1
  • 19
    • 0007663795 scopus 로고
    • Tests with the Chinese hamster V79 inhibition of metabolic cooperation assay
    • Elmore E, Korytynski A, Smith MP (1985) Tests with the Chinese hamster V79 inhibition of metabolic cooperation assay. Prog Mutat Res 5: 597-612
    • (1985) Prog Mutat Res , vol.5 , pp. 597-612
    • Elmore, E.1    Korytynski, A.2    Smith, M.P.3
  • 20
    • 0000060569 scopus 로고    scopus 로고
    • Proposed guidelines for carcinogen risk assessment notice
    • Environmental Protection Agency (1996) Proposed guidelines for carcinogen risk assessment notice. Federal Register 61: 17961-18011
    • (1996) Federal Register , vol.61 , pp. 17961-18011
  • 21
    • 0025127633 scopus 로고
    • Determination of aldehydie lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal
    • Esterbauer H, Cheeseman KH (1990) Determination of aldehydie lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol 186: 407-421
    • (1990) Methods Enzymol , vol.186 , pp. 407-421
    • Esterbauer, H.1    Cheeseman, K.H.2
  • 22
    • 0025045198 scopus 로고
    • The role of 8-hydroxyguanine in carcinogenesis
    • Floyd RA (1990a) The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 11: 1447-1450
    • (1990) Carcinogenesis , vol.11 , pp. 1447-1450
    • Floyd, R.A.1
  • 23
    • 0025314685 scopus 로고
    • Role of oxygen free radicals in carcinogenesis and brain ischemia
    • Floyd RA (1990b) Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 4: 2587-2597
    • (1990) FASEB J , vol.4 , pp. 2587-2597
    • Floyd, R.A.1
  • 24
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine
    • Fraga CG, Shigenaga MK, Park JP, Degen P, Ames BN (1990) Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine. Proc Natl Acad Sci USA 87: 4533-4537
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.P.3    Degen, P.4    Ames, B.N.5
  • 25
    • 0028982360 scopus 로고
    • 7,12-Dimethylbenz[a]anthracene induces oxidative DNA modification in vivo
    • Frenkel K , Wei L, Wei H (1995) 7,12-Dimethylbenz[a]anthracene induces oxidative DNA modification in vivo. Free Radic Biol Med 19: 373-380
    • (1995) Free Radic Biol Med , vol.19 , pp. 373-380
    • Frenkel, K.1    Wei, L.2    Wei, H.3
  • 26
    • 0000189906 scopus 로고
    • Relative nucleophilic reactivities of amino groups and mercaptide ions in addition reactions with unsaturated compounds
    • Friedman M, Cavins JF, Wall JS (1965) Relative nucleophilic reactivities of amino groups and mercaptide ions in addition reactions with unsaturated compounds. J Am Chem Soc 87: 3672-3682
    • (1965) J Am Chem Soc , vol.87 , pp. 3672-3682
    • Friedman, M.1    Cavins, J.F.2    Wall, J.S.3
  • 27
    • 0020585252 scopus 로고
    • Metabolism of acrylonitrile by isolated rat hepatocytes
    • Geiger LE, Hogy LL, Guengerich FP (1983) Metabolism of acrylonitrile by isolated rat hepatocytes. Cancer Res 43: 3080-3087
    • (1983) Cancer Res , vol.43 , pp. 3080-3087
    • Geiger, L.E.1    Hogy, L.L.2    Guengerich, F.P.3
  • 28
    • 0019825946 scopus 로고
    • In vitro metabolism of acrylonitrile to 2-cyanoethylcne oxide: Reaction with glutathione and irreversible binding to proteins and nucleic acids
    • Guengerich FP, Geiger LE, Hogy L, Wright PL (1981) In vitro metabolism of acrylonitrile to 2-cyanoethylcne oxide: reaction with glutathione and irreversible binding to proteins and nucleic acids. Cancer Res 41: 4925-4933
    • (1981) Cancer Res , vol.41 , pp. 4925-4933
    • Guengerich, F.P.1    Geiger, L.E.2    Hogy, L.3    Wright, P.L.4
  • 29
    • 0025972738 scopus 로고
    • DNA damage by oxygen-derived species: Its mechanism and measurement in mammalian systems
    • Halliwell B, Aruoma OI (1991) DNA damage by oxygen-derived species: its mechanism and measurement in mammalian systems. FEBS Lett 281: 9-19
    • (1991) FEBS Lett , vol.281 , pp. 9-19
    • Halliwell, B.1    Aruoma, O.I.2
  • 30
    • 0002903784 scopus 로고
    • Tumor incidences in Fischer 344 rats: NTP historical data
    • Boorman GA, Eustis SL, Elwell MR, Montgomery CA Jr, MacKenzie WF (eds) Academic Press, New York
    • Haseman JK, Arnold J, Eustis SL (1990) Tumor incidences in Fischer 344 rats: NTP historical data. In: Boorman GA, Eustis SL, Elwell MR, Montgomery CA Jr, MacKenzie WF (eds) Pathology of the Fischer rat: reference and atlas. Academic Press, New York, pp 555-564
    • (1990) Pathology of the Fischer Rat: Reference and Atlas , pp. 555-564
    • Haseman, J.K.1    Arnold, J.2    Eustis, S.L.3
  • 31
    • 0002654279 scopus 로고
    • Formation of 8-hydroxyguanine in DNA by aging and oxidative stress
    • Cutler RG, Packer L, Bertram J, Mori A (eds) Birkhäuser Verlag, Basel, Switzerland
    • Hirano T, Homma Y, Kasai H (1995) Formation of 8-hydroxyguanine in DNA by aging and oxidative stress. In: Cutler RG, Packer L, Bertram J, Mori A (eds) Oxidative stress and aging. Birkhäuser Verlag, Basel, Switzerland, pp 69-76
    • (1995) Oxidative Stress and Aging , pp. 69-76
    • Hirano, T.1    Homma, Y.2    Kasai, H.3
  • 32
    • 0022497049 scopus 로고
    • In vivo interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats
    • Hogy LL, Guengerich FP (1986) In vivo interaction of acrylonitrile and 2-cyanoethylene oxide with DNA in rats. Cancer Res 46 3932-3938
    • (1986) Cancer Res , vol.46 , pp. 3932-3938
    • Hogy, L.L.1    Guengerich, F.P.2
  • 33
    • 0029780851 scopus 로고    scopus 로고
    • The use of mechanistic data in the risk assessment of ten chemicals: An introduction to the chemical-specific reviews
    • International Expert Panel on Carcinogen Risk Assessment (1996) The use of mechanistic data in the risk assessment of ten chemicals: an introduction to the chemical-specific reviews. Pharmacol Ther 71: 1-5
    • (1996) Pharmacol Ther , vol.71 , pp. 1-5
  • 34
    • 14444284085 scopus 로고
    • IARC monographs on the evaluation of carcinogenic risks to humans
    • International Agency for Research on Cancer (1987a) IARC monographs on the evaluation of carcinogenic risks to humans. Genetic and related effects: an updating of selected IARC monographs from volumes 1 to 42, Suppl 6, pp 27-31
    • (1987) Genetic and Related Effects: An Updating of Selected IARC Monographs , vol.1-42 , Issue.6 SUPPL. , pp. 27-31
  • 35
    • 0038351753 scopus 로고
    • IARC monographs on the evaluation of carcinogenic risks to humans
    • International Agency for Research on Cancer (1987b) IARC monographs on the evaluation of carcinogenic risks to humans. Overall evaluations of carcinogenicity: an updating of IARC monographs from volumes 1 to 42, Suppl 7, pp 79-80
    • (1987) Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs , vol.1-42 , Issue.7 SUPPL. , pp. 79-80
  • 36
    • 0024451180 scopus 로고
    • Lipid peroxidation in acrylonitrile-treated rats, evidenced by elevated ethane production
    • Ivanov V, Rahier J, Lauwerys R (1989) Lipid peroxidation in acrylonitrile-treated rats, evidenced by elevated ethane production. J Appl Toxicol 9: 353-358
    • (1989) J Appl Toxicol , vol.9 , pp. 353-358
    • Ivanov, V.1    Rahier, J.2    Lauwerys, R.3
  • 37
    • 0023265078 scopus 로고
    • Peroxidation of brain lipids following cyanide intoxication in mice
    • Johnson JD, Conroy WG, Burris KD, Isom GE (1987) Peroxidation of brain lipids following cyanide intoxication in mice. Toxicology 46: 21-28
    • (1987) Toxicology , vol.46 , pp. 21-28
    • Johnson, J.D.1    Conroy, W.G.2    Burris, K.D.3    Isom, G.E.4
  • 38
    • 0029888579 scopus 로고    scopus 로고
    • Non-linear accumulation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidized DNa damage during aging
    • Kaneko T, Tahara S, Matsuo M (1996) Non-linear accumulation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidized DNA damage during aging. Mutat Res 316: 277-285
    • (1996) Mutat Res , vol.316 , pp. 277-285
    • Kaneko, T.1    Tahara, S.2    Matsuo, M.3
  • 39
    • 0025303448 scopus 로고
    • Evidence for carrier-mediated transport of glutathione across the blood-brain barrier in the rat
    • Kannan R, Kuhlenkamp JF, Jeandidier E, Trinh H, Ookhtens M, Kaplowitz N (1990) Evidence for carrier-mediated transport of glutathione across the blood-brain barrier in the rat. J Clin Invest 85: 2009-2013
    • (1990) J Clin Invest , vol.85 , pp. 2009-2013
    • Kannan, R.1    Kuhlenkamp, J.F.2    Jeandidier, E.3    Trinh, H.4    Ookhtens, M.5    Kaplowitz, N.6
  • 40
    • 0021769722 scopus 로고
    • Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents
    • Kasai H, Nishimura S (1984) Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Res 12: 2137-2145
    • (1984) Nucleic Acids Res , vol.12 , pp. 2137-2145
    • Kasai, H.1    Nishimura, S.2
  • 41
    • 0027408080 scopus 로고
    • Free radicals as mediators of tissue injury and disease
    • Kehrer JP (1993) Free radicals as mediators of tissue injury and disease. Crit Rev Toxicol 23: 21-48
    • (1993) Crit Rev Toxicol , vol.23 , pp. 21-48
    • Kehrer, J.P.1
  • 43
    • 0030043457 scopus 로고    scopus 로고
    • Measurement of 8-OHdG in DNA by HPLC ECD: The importance of DNA purity
    • Laws GM, Adams SP (1996) Measurement of 8-OHdG in DNA by HPLC ECD: the importance of DNA purity. Biotechniques 20: 36-38
    • (1996) Biotechniques , vol.20 , pp. 36-38
    • Laws, G.M.1    Adams, S.P.2
  • 44
    • 0018075342 scopus 로고
    • Effect of ischemic anoxia and barbiturate anesthesia on free radical oxidation of mitochondrial phospholipids
    • Majewska MD, Strosznajder J, Lazarewicz J (1978) Effect of ischemic anoxia and barbiturate anesthesia on free radical oxidation of mitochondrial phospholipids. Brain Res 158: 423-434
    • (1978) Brain Res , vol.158 , pp. 423-434
    • Majewska, M.D.1    Strosznajder, J.2    Lazarewicz, J.3
  • 45
    • 0028021753 scopus 로고
    • Selective 8-hydroxyguanine formation in pancreatic DNA due to a single intravenous administration of 4-hydroxyaminoquinoline 1-oxide in rats
    • Nakae D, Andoh N, Mizumoto Y, Endoh T, Shimoji N, Horiguchi K, Shiraiwa K, Tamura K, Denda A, Konishi Y (1994) Selective 8-hydroxyguanine formation in pancreatic DNA due to a single intravenous administration of 4-hydroxyaminoquinoline 1-oxide in rats. Cancer Lett 83: 97-103
    • (1994) Cancer Lett , vol.83 , pp. 97-103
    • Nakae, D.1    Andoh, N.2    Mizumoto, Y.3    Endoh, T.4    Shimoji, N.5    Horiguchi, K.6    Shiraiwa, K.7    Tamura, K.8    Denda, A.9    Konishi, Y.10
  • 46
    • 0003633755 scopus 로고
    • DHHS. National Institute of Health, Government Office Building, Washington, DC
    • NIH (1986) Guide for the care and use of laboratory animals. DHHS. National Institute of Health, Government Office Building, Washington, DC
    • (1986) Guide for the Care and Use of Laboratory Animals
  • 47
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70: 158-169
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 48
    • 0019847751 scopus 로고
    • Irreversible protein binding of acrylonitrile
    • Peter H, Bolt HM (1981) Irreversible protein binding of acrylonitrile. Xenobiotica 11: 51-56
    • (1981) Xenobiotica , vol.11 , pp. 51-56
    • Peter, H.1    Bolt, H.M.2
  • 49
    • 0027466198 scopus 로고
    • The effects of cyanide on brain mitochondrial cytochrome oxidase and respiratory activities
    • Pettersen JC, Cohen SD (1993) The effects of cyanide on brain mitochondrial cytochrome oxidase and respiratory activities. J Appl Toxicol 13: 9-14
    • (1993) J Appl Toxicol , vol.13 , pp. 9-14
    • Pettersen, J.C.1    Cohen, S.D.2
  • 52
    • 0029055175 scopus 로고
    • Oxidative processes and antioxidative defense mechanisms in the aging brain
    • Reiter RJ (1995) Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J 9: 526-533
    • (1995) FASEB J , vol.9 , pp. 526-533
    • Reiter, R.J.1
  • 53
    • 0029901755 scopus 로고    scopus 로고
    • Long-term stability of blood glutathione and cysteine in humans
    • Richie JP Jr, Abraham P, Leutzinger Y (1996) Long-term stability of blood glutathione and cysteine in humans. Clin Chem 42: 1100-1105
    • (1996) Clin Chem , vol.42 , pp. 1100-1105
    • Richie Jr., J.P.1    Abraham, P.2    Leutzinger, Y.3
  • 54
    • 0031157567 scopus 로고    scopus 로고
    • Quinolone antibiotic photodynamic production of 8-oxo-7, 8-dihydro-2′-deoxyguanosine in cultured liver epithelial cells
    • Rosen JE, Prahalad AK, Schluter G, Chen D, Williams GM (1997) Quinolone antibiotic photodynamic production of 8-oxo-7, 8-dihydro-2′-deoxyguanosine in cultured liver epithelial cells. Photochem Photobiol 65: 990-996.
    • (1997) Photochem Photobiol , vol.65 , pp. 990-996
    • Rosen, J.E.1    Prahalad, A.K.2    Schluter, G.3    Chen, D.4    Williams, G.M.5
  • 56
    • 0027299698 scopus 로고
    • 8-Aminoguanine: A base modification produced in rat liver nucleic acids by the hepatocarcinogen 2-nitropropane
    • Sodum RS, Nie G, Fiala ES (1993) 8-Aminoguanine: a base modification produced in rat liver nucleic acids by the hepatocarcinogen 2-nitropropane. Chem Res Toxicol 6: 269-276
    • (1993) Chem Res Toxicol , vol.6 , pp. 269-276
    • Sodum, R.S.1    Nie, G.2    Fiala, E.S.3
  • 57
    • 0024333729 scopus 로고
    • DNA adducts of propylene oxide and acrylonitrile epoxide: Hydrolytic deamination of 3-alkyl-dCyd to 3-alkyl-dUrd
    • Solomon JJ, Segal A (1989) DNA adducts of propylene oxide and acrylonitrile epoxide: hydrolytic deamination of 3-alkyl-dCyd to 3-alkyl-dUrd. Environ Health Perspect 81: 19-22
    • (1989) Environ Health Perspect , vol.81 , pp. 19-22
    • Solomon, J.J.1    Segal, A.2
  • 58
    • 0015256458 scopus 로고
    • The induction of tumors of the nervous system with intravenous methylnitrosourea
    • Swenberg JA, Koestner A, Wechsler W (1972) The induction of tumors of the nervous system with intravenous methylnitrosourea. Lab Invest 26: 74-85
    • (1972) Lab Invest , vol.26 , pp. 74-85
    • Swenberg, J.A.1    Koestner, A.2    Wechsler, W.3
  • 60
    • 0017762498 scopus 로고
    • Acrylonitrile and tissue glutathione: Differential effect of acute and chronic interaction
    • Szabo S, Bailey KA, Boor PJ, Jaeger RF (1977) Acrylonitrile and tissue glutathione: differential effect of acute and chronic interaction. Biochem Biophys Res Commun 79: 32-37
    • (1977) Biochem Biophys Res Commun , vol.79 , pp. 32-37
    • Szabo, S.1    Bailey, K.A.2    Boor, P.J.3    Jaeger, R.F.4
  • 61
    • 0029001483 scopus 로고
    • DNA adduct 8-hydroxyl-2′-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase
    • Turk PW, Laayoun A, Smith SS, Weitzman SA (1995) DNA adduct 8-hydroxyl-2′-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase. Carcinogenesis 16: 1253-1255
    • (1995) Carcinogenesis , vol.16 , pp. 1253-1255
    • Turk, P.W.1    Laayoun, A.2    Smith, S.S.3    Weitzman, S.A.4
  • 62
    • 0000772332 scopus 로고
    • Assays for inhibition of metabolic cooperation by a microassay method
    • Umeda M, Noda K, Tanaka K (1985) Assays for inhibition of metabolic cooperation by a microassay method. Prog Mutat Res 5: 619-622
    • (1985) Prog Mutat Res , vol.5 , pp. 619-622
    • Umeda, M.1    Noda, K.2    Tanaka, K.3
  • 63
    • 0004192590 scopus 로고
    • Definition of a human cancer hazard
    • Banbury report 25. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Williams GM (1987) Definition of a human cancer hazard. In: Nongenotoxic mechanisms in carcinogenesis. Banbury report 25. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp 367-380
    • (1987) Nongenotoxic Mechanisms in Carcinogenesis , pp. 367-380
    • Williams, G.M.1
  • 65
    • 0019816386 scopus 로고
    • Effects of intraperitoneally injected acrylonitrile on liver, kidney and brain
    • Zitting A, Tenhunen R, Savolainen H (1981) Effects of intraperitoneally injected acrylonitrile on liver, kidney and brain. Acta Pharmacol Toxicol 49: 412-415
    • (1981) Acta Pharmacol Toxicol , vol.49 , pp. 412-415
    • Zitting, A.1    Tenhunen, R.2    Savolainen, H.3


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