TEL-AML1 Corrupts Hematopoietic Stem Cells to Persist in the Bone Marrow and Initiate Leukemia

Cell Stem Cell

Volumn 5, Issue 1, 2009, Pages 43-53

  Schindler, Jeffrey W ^a,b   Van Buren, Denille ^a,b   Foudi, Adlen ^a,b   Krejci, Ondrej ^a,b   Qin, Jinzhong ^a,b   Orkin, Stuart H ^c,d,e,f   Hock, Hanno ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

CELLCYCLE; STEMCELL

Indexed keywords

TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR RUNX1;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CANCER SUSCEPTIBILITY; CELL COUNT; CELL CYCLE G0 PHASE; CELL RENEWAL; CONTROLLED STUDY; EMBRYO; FETUS; GENE EXPRESSION; GENE FUSION; GENE MUTATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALS; B-LYMPHOCYTES; BONE MARROW CELLS; CORE BINDING FACTOR ALPHA 2 SUBUNIT; CORE BINDING FACTORS; EMBRYONIC DEVELOPMENT; GENE TARGETING; HEMATOPOIETIC STEM CELLS; HEPATOCYTES; HUMANS; INTERLEUKIN-7; LEUKEMIA, MYELOID, ACUTE; MICE; MODELS, ANIMAL; ONCOGENE FUSION; ONCOGENE PROTEINS, FUSION; ONCOGENES;

MUS;

EID: 67649171660     PISSN: 19345909     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stem.2009.04.019     Document Type: Article

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