Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection

Clinical Cancer Research

Volumn 11, Issue 21, 2005, Pages 7720-7727

  Panzer Grümayer, E Renate ^a,b   Cazzaniga, Giovanni ^c   Van Der Velden, Vincent H J ^d   Del Giudice, Laura ^e   Peham, Martina ^a,b   Mann, Georg ^b   Eckert, Conny ^f   Schrauder, Andre ^g   Germano, Giuseppe ^e   Harbott, Jochen ^h   Basso, Giuseppe ^e   Biondi, Andrea ^c   Van Dongen, Jacques J M ^d   Gadner, Helmut ^a,b   Haas, Oskar A ^a,b  

^a CHILDREN'S CANCER RESEARCH INSTITUTE   (Austria)

^b ST ANNA CHILDREN S HOSPITAL   (Austria)

^c SAN GERARDO HOSPITAL   (Italy)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF PADOVA   (Italy)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER DIAGNOSIS; CANCER RECURRENCE; CANCER REGRESSION; CANCER RELAPSE; CHILD; CLONAL VARIATION; GENE FUSION; GENE REARRANGEMENT; GENOTYPE; HUMAN; IMMUNOGENETICS; LATENT PERIOD; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE RECEPTOR GENE; TEL AML1 GENE;

ADOLESCENT; AGE FACTORS; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; BONE MARROW CELLS; CHILD; CHILD, PRESCHOOL; CORE BINDING FACTOR ALPHA 2 SUBUNIT; GENE DELETION; GENE REARRANGEMENT; GENETIC TECHNIQUES; GENOTYPE; HUMANS; IMMUNE SYSTEM; IMMUNOGLOBULINS; INFANT; LEUKEMIA, LYMPHOCYTIC, ACUTE; ONCOGENE PROTEINS, FUSION; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL; RECURRENCE; REMISSION INDUCTION; TIME FACTORS; TRANSLOCATION, GENETIC;

EID: 27744484826     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-1239     Document Type: Article

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